2023

Wedel, Saskia (2023)
Investigation of SAFit2 as a potential treatment option for nerve injury- and chemotherapy-induced neuropathic pain.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026434
Dissertation, Erstveröffentlichung, Verlagsversion

Sharifzadeh, Atiyehsadat (2023)
HCN4 pacemaker channels as potential therapeutic targets based on their novel structural properties.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024625
Dissertation, Erstveröffentlichung, Verlagsversion

Krumbach, Jan H. ; Bauer, Daniel ; Sharifzadeh, Atiyeh Sadat ; Saponaro, Andrea ; Lautenschläger, Rene ; Lange, Kristina ; Rauh, Oliver ; DiFrancesco, Dario ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2023)
Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.
In: The Journal of general physiology, 155 (10)
doi: 10.1085/jgp.202313364
Artikel, Bibliographie

Engel, Anja J. ; Paech, Steffen ; Langhans, Markus ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2023)
Combination of hydrophobicity and codon usage bias determines sorting of model K+ channel protein to either mitochondria or endoplasmic reticulum.
In: Traffic, 24 (11)
doi: 10.1111/tra.12915
Artikel, Bibliographie

Höler, Sebastian ; Degreif, Daniel ; Stix, Florentine ; Yang, Shang ; Gao, Shiqiang ; Nagel, Georg ; Moroni, Anna ; Thiel, Gerhard ; Bertl, Adam ; Rauh, Oliver (2023)
Tailoring baker's yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin.
In: PloS one, 18 (4)
doi: 10.1371/journal.pone.0280711
Artikel, Bibliographie

2022

Harrison, Neil L. ; Abbott, Geoffrey W. ; Gentzsch, Martina ; Aleksandrov, Andrei ; Moroni, Anna ; Thiel, Gerhard ; Grant, Stephen ; Nichols, Colin G. ; Lester, Henry A. ; Hartel, Andreas ; Shepard, Kenneth ; Garcia, David Cabrera ; Yazawa, Masayuki (2022)
How many SARS-CoV-2 "viroporins" are really ion channels?
In: Communications biology, 5 (1)
doi: 10.1038/s42003-022-03669-2
Artikel, Bibliographie

Tandl, Dominique ; Sponagel, Tim ; Alansary, Dalia ; Fuck, Sebastian ; Smit, Timo ; Hehlgans, Stephanie ; Jakob, Burkhard ; Fournier, Claudia ; Niemeyer, Barbara A. ; Rödel, Franz ; Roth, Bastian ; Moroni, Anna ; Thiel, Gerhard (2022)
X-ray irradiation triggers immune response in human T-lymphocytes via store-operated Ca2+ entry and NFAT activation.
In: The Journal of general physiology, 154 (5)
doi: 10.1085/jgp.202112865
Artikel, Bibliographie

Rauh, Oliver ; Opper, Jennifer ; Sturm, Maximilian ; Drexler, Nils ; Scheub, Deborah D. ; Hansen, Ulf-Peter ; Thiel, Gerhard ; Schroeder, Indra (2022)
Role of ion distribution and energy barriers for concerted motion of subunits in selectivity filter gating of a K+ channel.
In: Journal of molecular biology, 434 (9)
doi: 10.1016/j.jmb.2022.167522
Artikel, Bibliographie

Carvalho-de-Souza, Joao Luis ; Saponaro, Andrea ; Bassetto, C. A. Z. ; Rauh, Oliver ; Schroeder, Indra ; Franciolini, Fabio ; Catacuzzeno, Luigi ; Bezanilla, Francisco ; Thiel, Gerhard ; Moroni, Anna (2022)
Experimental challenges in ion channel research : uncovering basic principles of permeation and gating in potassium channels.
In: Advances in Physics: X, 7 (1)
doi: 10.1080/23746149.2021.1978317
Artikel, Bibliographie

Brocca, Lorenzo (2022)
Towards the engineering of a magneto sensitive potassium channel.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00020264
Dissertation, Erstveröffentlichung, Verlagsversion

Schulze, Tobias (2022)
Structure and function analysis of two channel forming membrane proteins of medical importance – The lysosomal Transmembrane Protein 175 and the Envelope Protein of SARS-CoV-2.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019792
Dissertation, Erstveröffentlichung, Verlagsversion

Bauer, Daniel ; Wissmann, Jan ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2022)
Weak Cation Selectivity in HCN Channels Results From K+-Mediated Release of Na+ From Selectivity Filter Binding Sites.
In: Function (Oxford, England), 3 (3)
doi: 10.1093/function/zqac019
Artikel, Bibliographie

Scheiper-Welling, Stefanie (2022)
Molecular genetic analyses in hereditary cardiac arrhythmia syndromes.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00022880
Dissertation, Erstveröffentlichung, Verlagsversion

Köhs, Lukas ; Kukovetz, Kerri ; Rauh, Oliver ; Koeppl, Heinz (2022)
Nonparametric Bayesian inference for meta-stable conformational dynamics.
In: Physical Biology, 19 (5)
doi: 10.1088/1478-3975/ac885e
Artikel, Bibliographie

2021

Saponaro, Andrea ; Thiel, Gerhard ; Moroni, Anna (2021)
Structural and functional approaches to studying cAMP regulation of HCN channels.
In: Biochemical Society transactions
doi: 10.1042/BST20210290
Artikel, Bibliographie

Gabriel, Tobias S. ; Hansen, Ulf-Peter ; Urban, Martin ; Drexler, Nils ; Winterstein, Tobias ; Rauh, Oliver ; Thiel, Gerhard ; Kast, Stefan M. ; Schroeder, Indra (2021)
Asymmetric Interplay Between K+ and Blocker and Atomistic Parameters From Physiological Experiments Quantify K+ Channel Blocker Release.
In: Frontiers in physiology, 12
doi: 10.3389/fphys.2021.737834
Artikel, Bibliographie

Conti Nibali, Stefano ; Di Rosa, Maria Carmela ; Rauh, Oliver ; Thiel, Gerhard ; Reina, Simona ; De Pinto, Vito (2021)
Cell-free electrophysiology of human VDACs incorporated into nanodiscs : an improved method.
In: Biophysical reports, 1 (1)
doi: 10.1016/j.bpr.2021.100002
Artikel, Bibliographie

Saponaro, Andrea ; Bauer, Daniel ; Giese, M. Hunter ; Swuec, Paolo ; Porro, Alessandro ; Gasparri, Federica ; Sharifzadeh, Atiyeh Sadat ; Chaves-Sanjuan, Antonio ; Alberio, Laura ; Parisi, Giacomo ; Cerutti, Gabriele ; Clarke, Oliver B. ; Hamacher, Kay ; Colecraft, Henry M. ; Mancia, Filippo ; Hendrickson, Wayne A. ; Siegelbaum, Steven A. ; DiFrancesco, Dario ; Bolognesi, Martino ; Thiel, Gerhard ; Santoro, Bina ; Moroni, Anna (2021)
Gating movements and ion permeation in HCN4 pacemaker channels.
In: Molecular cell, 81 (14)
doi: 10.1016/j.molcel.2021.05.033
Artikel, Bibliographie

Engel, Anja J. ; Kithil, Marina ; Langhans, Markus ; Rauh, Oliver ; Cartolano, Matea ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2021)
Codon Bias Can Determine Sorting of a Potassium Channel Protein.
In: Cells, 10 (5)
doi: 10.3390/cells10051128
Artikel, Bibliographie

Rauh, Oliver ; Kukovetz, Kerri ; Winterstein, Laura ; Introini, Bianca ; Thiel, Gerhard (2021)
Combining in vitro translation with nanodisc technology and functional reconstitution of channels in planar lipid bilayers.
In: Methods in enzymology, 652
doi: 10.1016/bs.mie.2021.02.003
Artikel, Bibliographie

Winterstein, Laura-Marie ; Kukovetz, Kerri ; Hansen, Ulf-Peter ; Schroeder, Indra ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2021)
Distinct lipid bilayer compositions have general and protein-specific effects on K+ channel function.
In: The Journal of general physiology, 153 (2)
doi: 10.1085/jgp.202012731
Artikel, Bibliographie

Schmidt, Michael ; Schroeder, Indra ; Bauer, Daniel ; Thiel, Gerhard ; Hamacher, Kay (2021)
Inferring functional units in ion channel pores via relative entropy.
In: European biophysics journal : EBJ, 50 (1)
doi: 10.1007/s00249-020-01480-7
Artikel, Bibliographie

Tandl, Dominique (2021)
X-ray irradiation triggers via ROS production a canonical Ca2+-dependent immune response in T-lymphocytes.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00015402
Dissertation, Erstveröffentlichung, Verlagsversion

Ott, Marcus W. ; Dietz, Christian ; Trosien, Simon ; Mehlhase, Sabrina ; Bitsch, Martin J. ; Nau, Maximilian ; Meckel, Tobias ; Geissler, Andreas ; Siegert, Gregor ; Huong, Jasmin ; Hertel, Brigitte ; Stark, Robert W. ; Biesalski, Markus (2021)
Co-curing of epoxy resins with aminated lignins: insights into the role of lignin homo crosslinking during lignin amination on the elastic properties.
In: Holzforschung, 75 (4)
doi: 10.1515/hf-2020-0060
Artikel, Bibliographie

Höler, Sebastian (2021)
Metabolic engineering and adaption of Saccharomyces cerevisiae for biotechnological applications.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019678
Dissertation, Erstveröffentlichung, Verlagsversion

2020

Scheiper-Welling, Stefanie ; Zuccolini, Paolo ; Rauh, Oliver ; Beckmann, Britt-Maria ; Geisen, Christof ; Moroni, Anna ; Thiel, Gerhard ; Kauferstein, Silke (2020)
Characterization of an N-terminal Na v 1.5 channel variant - a potential risk factor for arrhythmias and sudden death?
In: BMC medical genetics, 21 (1)
doi: 10.1186/s12881-020-01170-3
Artikel, Bibliographie

Engel, Anja J. ; Winterstein, Laura-Marie ; Kithil, Marina ; Langhans, Markus ; Moroni, Anna ; Thiel, Gerhard (2020)
Light-Regulated Transcription of a Mitochondrial-Targeted K+ Channel.
In: Cells, 9 (11)
doi: 10.3390/cells9112507
Artikel, Bibliographie

Kukovetz, Kerri ; Hertel, Brigitte ; Schvarcz, Christopher R. ; Saponaro, Andrea ; Manthey, Mirja ; Burk, Ulrike ; Greiner, Timo ; Steward, Grieg F. ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2020)
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
In: Viruses, 12 (10)
doi: 10.3390/v12101107
Artikel, Bibliographie

Kukovetz, Kerri (2020)
Systematic Analyses of structure/function variability of viral K+ channels for the development of synthetic channels.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011813
Dissertation, Erstveröffentlichung

Engel, Anja Jeannine (2020)
Potassium channel-based optogenetic tool development - Establishment and optimization of compartment-specific light-inducible silencing tools.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011782
Dissertation, Erstveröffentlichung

Porro, Alessandro ; Thiel, Gerhard ; Moroni, Anna ; Saponaro, Andrea (2020)
Cyclic AMP Regulation and Its Command in the Pacemaker Channel HCN4.
In: Frontiers in physiology, 11
doi: 10.3389/fphys.2020.00771
Artikel, Bibliographie

Murry, Carter R. ; Agarkova, Irina V. ; Ghosh, Jayadri S. ; Fitzgerald, Fiona C. ; Carlson, Roger M. ; Hertel, Brigitte ; Kukovetz, Kerri ; Rauh, Oliver ; Thiel, Gerhard ; Etten, James L. van (2020)
Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae.
In: Viruses, 12 (6)
doi: 10.3390/v12060678
Artikel, Bibliographie

Brunner, Janine D. ; Jakob, Roman P. ; Schulze, Tobias ; Neldner, Yvonne ; Moroni, Anna ; Thiel, Gerhard ; Maier, Timm ; Schenck, Stephan (2020)
Structural basis for ion selectivity in TMEM175 K+ channels.
In: eLife, 9
doi: 10.7554/eLife.53683
Artikel, Bibliographie

Jenewein, Tina ; Kanner, Scott A. ; Bauer, Daniel ; Hertel, Brigitte ; Colecraft, Henry M. ; Moroni, Anna ; Thiel, Gerhard ; Kauferstein, Silke (2020)
The mutation L69P in the PAS domain of the hERG potassium channel results in LQTS by trafficking deficiency.
In: Channels (Austin, Tex.), 14 (1)
doi: 10.1080/19336950.2020.1751522
Artikel, Bibliographie

Taiz, Lincoln ; Alkon, Daniel ; Draguhn, Andreas ; Murphy, Angus ; Blatt, Michael ; Thiel, Gerhard ; Robinson, David G (2020)
Reply to Trewavas et al. and Calvo and Trewavas.
In: Trends in plant science, 25 (3)
doi: 10.1016/j.tplants.2019.12.020
Artikel, Bibliographie

Kleuter, Marietheres ; Thiel, Gerhard ; Rauh, Oliver (2020)
Asymmetric Mutations in Selectivity Filter of K+ Channel Pore Generate C-type Inactivation.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.1030
Artikel, Bibliographie

Thiel, Gerhard ; Engel, Anja J. ; Kukovetz, Kerri ; Cortolano, Matea ; Höler, Sebastian ; Beltrame, Monica ; Moroni, Anna (2020)
A Modular Toolbox for Optogenetic Manipulation of K+Conductance.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2673
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2020)
Camp-Induced Conformational Changes in the C-Linker of HCN4.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2365
Artikel, Bibliographie

Laskowski, Michal ; Saponaro, Andrea ; Porro, Alessandro ; Zurbriggen, Matias ; Thiel, Gerhard ; Moroni, Anna (2020)
Lov-Nano as a New Tool for the Regulation of HCN Channels by Blue Light.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.1558
Artikel, Bibliographie

Porro, Alessandro ; Gasparri, Federica ; Cona, Filippo ; Thiel, Gerhard ; Thei, Federico ; Santoro, Bina ; Saponaro, Andrea ; Moroni, Anna (2020)
The Role of HCN Channel Helices D and E in the Modulation of Camp Affinity.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2350
Artikel, Bibliographie

Winterstein, Tobias (2020)
Quaternary ammonium cations are a useful tool to investigate viral potassium channels.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011324
Dissertation, Erstveröffentlichung

2019

Eckert, Denise ; Schulze, Tobias ; Stahl, Julian ; Rauh, Oliver ; Etten, James L. van ; Hertel, Brigitte ; Schroeder, Indra ; Moroni, Anna ; Thiel, Gerhard (2019)
A small viral potassium ion channel with an inherent inward rectification.
In: Channels (Austin, Tex.), 13 (1)
Artikel, Bibliographie

Porro, Alessandro ; Saponaro, Andrea ; Gasparri, Federica ; Bauer, Daniel ; Gross, Christine ; Pisoni, Matteo ; Abbandonato, Gerardo ; Hamacher, Kay ; Santoro, Bina ; Thiel, Gerhard ; Moroni, Anna (2019)
The HCN domain couples voltage gating and cAMP response in Hyperpolarization-activated Cyclic Nucleotide-gated channels.
In: eLife, 8
doi: 10.7554/eLife.49672
Artikel, Bibliographie

Bandmann, Vera ; Mirsanaye, Ann Schirin ; Schäfer, Johanna ; Thiel, Gerhard ; Holstein, Thomas ; Mikosch-Wersching, Melanie (2019)
Membrane capacitance recordings resolve dynamics and complexity of receptor-mediated endocytosis in Wnt signalling.
In: Scientific reports, 9 (1)
doi: 10.1038/s41598-019-49082-4
Artikel, Bibliographie

Taiz, Lincoln ; Alkon, Daniel ; Draguhn, Andreas ; Murphy, Angus ; Blatt, Michael ; Hawes, Chris ; Thiel, Gerhard ; Robinson, David G (2019)
Plants Neither Possess nor Require Consciousness.
In: Trends in plant science, 24 (8)
doi: 10.1016/j.tplants.2019.05.008
Artikel, Bibliographie

Hartel, Andreas J. W. ; Shekar, Siddharth ; Ong, Peijie ; Schroeder, Indra ; Thiel, Gerhard ; Shepard, Kenneth L. (2019)
High bandwidth approaches in nanopore and ion channel recordings - A tutorial review.
In: Analytica chimica acta, 1061
doi: 10.1016/j.aca.2019.01.034
Artikel, Bibliographie

Winterstein, Laura-Marie (2019)
Einflüsse verschiedener Membranen auf die viralen Kaliumkanäle KcvNTS, KcvS und Kmpv12T.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Khoury, Mario El ; Winterstein, Tobias ; Weber, Wadim ; Stein, Viktor ; Schlaak, Helmut F. ; Thiel, Gerhard (2019)
Photolithographic Fabrication of Micro Apertures in Dry Film Polymer Sheets for Channel Recordings in Planar Lipid Bilayers.
In: The Journal of membrane biology, 252 (2/3)
doi: 10.1007/s00232-019-00062-9
Artikel, Bibliographie

Degreif, Daniel ; Cucu, Bayram ; Budin, Itay ; Thiel, Gerhard ; Bertl, Adam (2019)
Lipid determinants of endocytosis and exocytosis in budding yeast.
In: Biochimica et biophysica acta. Molecular and cell biology of lipids, 1864 (7)
doi: 10.1016/j.bbalip.2019.03.007
Artikel, Bibliographie

Zuccolini, Paolo (2019)
Application of optogentetic principles for the modulation of the pacemaker current If.
Università degli Studi di Milano; Technische Universität Darmstadt
doi: 10.25534/tuprints-00009649
Dissertation, Erstveröffentlichung

Schönrock, Michael ; Thiel, Gerhard ; Laube, Bodo (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.
In: Communications biology, 2
doi: 10.1038/s42003-019-0320-y
Artikel, Bibliographie

Moroni, Anna ; Porro, Alessandro ; Saponaro, Andrea ; Pisoni, Matteo ; Gasparri, Federica ; Abbandonato, Gerardo ; Thiel, Gerhard ; Santoro, Bina (2019)
The Role of HCN Domain in Channel Gating.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.2146
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2019)
Chimeric HCN Channels for Studying Camp-Induced Conformational Changes in the C-Linker.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.1631
Artikel, Bibliographie

Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Laskowski, Michal ; Mesirca, Pietro ; Mangoni, Matteo ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2019)
Developing Synthetic Peptides to Regulate Native HCN Channels.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.1638
Artikel, Bibliographie

Thiel, Gerhard ; Kukovetz, Kerri ; Engel, Anja ; Moroni, Anna (2019)
Impact of Codon Usage and Prolyl Isomerization on K Channel Function.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.2148
Artikel, Bibliographie

Kithil, Marina (2019)
Die Sortierung von Membranproteinen: Der Einfluss der codon usage auf die Sortierung von Modell-Kaliumkanälen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Eckert, Denise (2019)
Analyse von zwei strukturell ähnlichen aber funktionell unterschiedlichen viralen K+-Kanälen: Strukturelle Ursache der inhärenten Einwärtsgleichrichtung.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

2018

Marini, Carla ; Porro, Alessandro ; Rastetter, Agnès ; Dalle, Carine ; Rivolta, Ilaria ; Bauer, Daniel ; Oegema, Renske ; Nava, Caroline ; Parrini, Elena ; Mei, Davide ; Mercer, Catherine ; Dhamija, Radhika ; Chambers, Chelsea ; Coubes, Christine ; Thévenon, Julien ; Kuentz, Paul ; Julia, Sophie ; Pasquier, Laurent ; Dubourg, Christèle ; Carré, Wilfrid ; Rosati, Anna ; Melani, Federico ; Pisano, Tiziana ; Giardino, Maria ; Innes, A. Micheil ; Alembik, Yves ; Scheidecker, Sophie ; Santos, Manuela ; Figueiroa, Sonia ; Garrido, Cristina ; Fusco, Carlo ; Frattini, Daniele ; Spagnoli, Carlotta ; Binda, Anna ; Granata, Tiziana ; Ragona, Francesca ; Freri, Elena ; Franceschetti, Silvana ; Canafoglia, Laura ; Castellotti, Barbara ; Gellera, Cinzia ; Milanesi, Raffaella ; Mancardi, Maria Margherita ; Clark, Damien R. ; Kok, Fernando ; Helbig, Katherine L. ; Ichikawa, Shoji ; Sadler, Laurie ; Neupauerová, Jana ; Laššuthova, Petra ; Šterbová, Katalin ; Laridon, Annick ; Brilstra, Eva ; Koeleman, Bobby ; Lemke, Johannes R. ; Zara, Federico ; Striano, Pasquale ; Soblet, Julie ; Smits, Guillaume ; Deconinck, Nicolas ; Barbuti, Andrea ; DiFrancesco, Dario ; LeGuern, Eric ; Guerrini, Renzo ; Santoro, Bina ; Hamacher, Kay ; Thiel, Gerhard ; Moroni, Anna ; DiFrancesco, Jacopo C. ; Depienne, Christel (2018)
HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond.
In: Brain : a journal of neurology, 141 (11)
Artikel, Bibliographie

Alberio, Laura ; Locarno, Andrea ; Saponaro, Andrea ; Romano, Edoardo ; Bercier, Valérie ; Albadri, Shahad ; Simeoni, Frederica ; Moleri, Silvia ; Pelucchi, Silvia ; Porro, Alessandro ; Marcello, Elena ; Barsotti, Noemi ; Kukovetz, Kerri ; Boender, Arjen J. ; Contestabile, Andrea ; Luo, Shizhen ; Moutal, Aubin ; Ji, Yingshi ; Romani, Giulia ; Beltrame, Monica ; Del Bene, Filippo ; Di Luca, Monica ; Khanna, Rajesh ; Colecraft, Henry M. ; Pasqualetti, Massimo ; Thiel, Gerhard ; Tonini, Raffaella ; Moroni, Anna (2018)
A light-gated potassium channel for sustained neuronal inhibition.
In: Nature methods, 15 (11)
Artikel, Bibliographie

Greiner, Timo ; Moroni, Anna ; Etten, James L. van ; Thiel, Gerhard (2018)
Genes for Membrane Transport Proteins: Not So Rare in Viruses.
In: Viruses, 10 (9)
doi: 10.3390/v10090456
Artikel, Bibliographie

Groß, Christine ; Saponaro, Andrea ; Santoro, Bina ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2018)
Mechanical transduction of cytoplasmic-to-transmembrane-domain movements in a hyperpolarization-activated cyclic nucleotide-gated cation channel.
In: The Journal of biological chemistry, 293 (33)
doi: 10.1074/jbc.RA118.002139
Artikel, Bibliographie

Rondelli, V. ; Favero, E. del ; Brocca, P. ; Fragneto, G. ; Trapp, M. ; Mauri, L. ; Ciampa, M. G. ; Romani, G. ; Braun, C. J. ; Winterstein, L. ; Schroeder, Indra ; Thiel, Gerhard ; Moroni, Anna ; Cantu', L. (2018)
Directional K+ channel insertion in a single phospholipid bilayer: Neutron reflectometry and electrophysiology in the joint exploration of a model membrane functional platform.
In: Biochimica et biophysica acta, 1862 (8)
Artikel, Bibliographie

Rauh, O. ; Hansen, U. P. ; Scheub, D. D. ; Thiel, Gerhard ; Schroeder, Indra (2018)
Site-specific ion occupation in the selectivity filter causes voltage-dependent gating in a viral K+ channel.
In: Scientific reports, 8 (1)
Artikel, Bibliographie

Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Donadoni, Chiara ; Introini, Bianca ; Mesirca, Pietro ; Mangoni, Matteo Elia ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2018)
A synthetic peptide that prevents cAMP regulation in mammalian Hyperpolarization-activated Cyclic Nucleotide-regulated (HCN) channels.
In: eLife, 7
Artikel, Bibliographie

Rödel, Franz ; Voos, Patrick ; Fuck, Sebastian ; Weipert, Fabian ; Babel, Laura ; Tandl, Dominique ; Meckel, Tobias ; Fournier, Claudia ; Moroni, Anna ; Thiel, Gerhard (2018)
Ionizing radiation induces morphological changes and immunological modulation of Jurkat cells and naive T cells.
In: Strahlentherapie und Onkologie, 194
Artikel, Bibliographie

Rauh, Oliver (2018)
Molecular explanations for gating in simple model K+ channels.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Winterstein, Laura-Marie ; Kukovetz, Kerri ; Rauh, Oliver ; Turman, Daniel L. ; Braun, Christian ; Moroni, Anna ; Schroeder, Indra ; Thiel, Gerhard (2018)
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers.
In: The Journal of general physiology, 150 (4)
Artikel, Bibliographie

Smeazzetto, Serena ; Tadini-Buoninsegni, Francesco ; Thiel, Gerhard ; Moncelli, Maria Rosa (2018)
Selectivity of the phospholamban ion channel investigated by single channel measurements.
In: Journal of Electroanalytical Chemistry, 812
doi: 10.1016/j.jelechem.2018.01.028
Artikel, Bibliographie

Jenewein, Tina ; Neumann, Thomas ; Erkapic, Damir ; Kuniss, Malte ; Verhoff, Marcel A. ; Thiel, Gerhard ; Kauferstein, Silke (2018)
Influence of genetic modifiers on sudden cardiac death cases.
In: International journal of legal medicine, 132 (2)
Artikel, Bibliographie

Kukovetz, Kerri ; Engel, Anja ; Gutsfeld, Sebastian ; Kithil, Marina ; Rauh, Oliver ; Moroni, Anna ; Thiel, Gerhard (2018)
Codon Usage Influences Gating of Small K+ Channels.
In: Biophysical journal, 114 (3)
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Donadoni, Chiara ; Santoro, Bina ; Thiel, Gerhard ; Moroni, Anna (2018)
Assigning Function to the D and E Helices of HCN CNBD.
In: Biophysical journal, 114 (3)
Artikel, Bibliographie

Hartel, Andreas J. W. ; Ong, Peijie ; Schroeder, Indra ; Giese, M. Hunter ; Shekar, Siddharth ; Clarke, Oliver B. ; Zalk, Ran ; Marks, Andrew R. ; Hendrickson, Wayne A. ; Shepard, Kenneth L. (2018)
Single-channel recordings of RyR1 at microsecond resolution in CMOS-suspended membranes.
In: Proceedings of the National Academy of Sciences, 115 (8)
doi: 10.1073/pnas.1712313115
Artikel, Bibliographie

Voos, Patrick ; Fuck, Sebastian ; Weipert, Fabian ; Babel, Laura ; Tandl, Dominique ; Meckel, Tobias ; Hehlgans, Stephanie ; Fournier, Claudia ; Moroni, Anna ; Rödel, Franz ; Thiel, Gerhard (2018)
Ionizing Radiation Induces Morphological Changes and Immunological Modulation of Jurkat Cells.
In: Frontiers in Immunology, 9
doi: 10.3389/fimmu.2018.00922
Artikel, Bibliographie

2017

Rauh, O. ; Hansen, U. P. ; Mach, S. ; Hartel, A. J. W. ; Shepard, K. L. ; Thiel, Gerhard ; Schroeder, Indra (2017)
Extended beta distributions open the access to fast gating in bilayer experiments: assigning the voltage-dependent gating to the selectivity filter.
In: FEBS letters, 591 (23)
Artikel, Bibliographie

Cucu, Bayram ; Degreif, Daniel ; Bertl, Adam ; Thiel, Gerhard (2017)
Vesicle fusion and fission in plants and yeast.
In: Cell calcium, 67
Artikel, Bibliographie

Scheiper, Stefanie ; Hertel, Brigitte ; Beckmann, Britt-Maria ; Kääb, Stefan ; Thiel, Gerhard ; Kauferstein, Silke (2017)
Characterization of a novel KCNJ2 sequence variant detected in Andersen-Tawil syndrome patients.
In: BMC medical genetics, 18 (1)
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Chaves-Sanjuan, Antonio ; Nardini, Marco ; Rauh, Oliver ; Thiel, Gerhard ; Moroni, Anna (2017)
Fusicoccin Activates KAT1 Channels by Stabilizing their Interaction with 14-3-3- Proteins.
In: The Plant cell, 29 (10)
Artikel, Bibliographie

Voos, Patrick ; Yazar, Mehtap ; Lautenschläger, René ; Rauh, Oliver ; Moroni, Anna ; Thiel, Gerhard (2017)
The small neurotoxin apamin blocks not only small conductance Ca(2+) activated K(+) channels (SK type) but also the voltage dependent Kv1.3 channel.
In: European biophysics journal : EBJ, 46 (6)
Artikel, Bibliographie

Fuck, Sebastian (2017)
Kurz- und Langzeiteffekte ionisierender Strahlung auf die T-Zelllinie Jurkat.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Rauh, Oliver ; Urban, Martin ; Henkes, Leonhard M. ; Winterstein, Tobias ; Greiner, Timo ; Etten, James L. van ; Moroni, Anna ; Kast, Stefan M. ; Thiel, Gerhard ; Schroeder, Indra (2017)
Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K(+) Channels.
In: Journal of the American Chemical Society, 139 (22)
Artikel, Bibliographie

Jenewein, Tina (2017)
Characterization of sequence variants in the cardiac ion channel genes KCNH2 and SCN5A.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Schoenrock, Michael ; Poci, Alina ; Thiel, Gerhard ; Laube, Bodo (2017)
Design of a Glutamate-Activated Potassium Channel upon Fusion of the Ligand-Binding Domain of the Mammalian AMPA Receptor Glua1 to the Channel Pore of the Viral ATCV-1 KCV K+ Channel.
In: Biophysical journal, 112 (3)
Artikel, Bibliographie

Alberio, Laura S. ; Defranceschi, Giordano ; Simeoni, Frederica ; Zuccolini, Paolo ; Thiel, Gerhard ; Moroni, Anna (2017)
Improving Trafficking and Kinetics of a Synthetic Light-Gated Potassium Channel.
In: Biophysical journal, 112 (3)
doi: 10.1016/j.bpj.2016.11.954
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Sanjuan, Antonio C. ; Donadoni, Chiara ; Nardini, Marco ; Thiel, Gerhard ; Moroni, Anna (2017)
Exploring New Pharmacological Perspectives of Fusicoccin, A Stabilizer of 14-3-3-Target Protein Complex.
In: Biophysical journal, 112 (3)
Artikel, Bibliographie

Weißgraeber, Stephanie ; Saponaro, Andrea ; Thiel, Gerhard ; Hamacher, Kay (2017)
A reduced mechanical model for cAMP-modulated gating in HCN channels.
In: Scientific reports, 7
Artikel, Bibliographie

Baumeister, Dirk ; Hertel, Brigitte ; Schroeder, Indra ; Gazzarrini, Sabrina ; Kast, Stefan M. ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2017)
Conversion of an instantaneous activating K(+) channel into a slow activating inward rectifier.
In: FEBS letters, 591 (2)
Artikel, Bibliographie

Cosentino, Cristian ; Alberio, Laura ; Thiel, Gerhard ; Moroni, Anna (2017)
Yeast-Based Screening System for the Selection of Functional Light-Driven K(+) Channels.
In: Methods in molecular biology (Clifton, N.J.), 1596
Artikel, Bibliographie

Cucu, Aljona ; Shreder, Kateryna ; Kraft, Daniela ; Rühle, Paul Friedrich ; Klein, Gerhart ; Thiel, Gerhard ; Frey, Benjamin ; Gaipl, Udo S. ; Fournier, Claudia (2017)
Decrease of Markers Related to Bone Erosion in Serum of Patients with Musculoskeletal Disorders after Serial Low-Dose Radon Spa Therapy.
In: Frontiers in immunology, 8
doi: 10.3389/fimmu.2017.00882
Artikel, Bibliographie

Rauh, Oliver ; Hansen, Ulf-Peter ; Mach, Sebastian ; Hartel, Andreas J. W. ; Shepard, Kenneth L. ; Thiel, Gerhard ; Schroeder, Indra (2017)
Extended beta distributions open the access to fast gating in bilayer experiments-assigning the voltage-dependent gating to the selectivity filter.
In: FEBS Letters, 591 (23)
doi: 10.1002/1873-3468.12898
Artikel, Bibliographie

2016

Smeazzetto, S. ; Tadini-Buoninsegni, F. ; Thiel, Gerhard ; Berti, D. ; Montis, C. (2016)
Phospholamban spontaneously reconstitutes into giant unilamellar vesicles where it generates a cation selective channel.
In: Physical chemistry chemical physics : PCCP, 18 (3)
doi: 10.1039/c5cp05893g
Artikel, Bibliographie

Lee, Seung-Woo ; Lee, Eun-Hee ; Thiel, Gerhard ; Etten, James L. van ; Saraf, Ravi F. (2016)
Noninvasive Measurement of Electrical Events Associated with a Single Chlorovirus Infection of a Microalgal Cell.
In: ACS nano, 10 (5)
Artikel, Bibliographie

Zhang, Ying ; Schäffer, Thea ; Wölfle, Tina ; Fitzke, Edith ; Thiel, Gerhard ; Rospert, Sabine (2016)
Cotranslational intersection between the SRP and GET targeting pathways to the ER of Saccharomyces cerevisiae.
In: Molecular and cellular biology, 36 (18)
Artikel, Bibliographie

Biel, Stephanie ; Aquila, Marco ; Hertel, Brigitte ; Berthold, Anne ; Neumann, Thomas ; DiFrancesco, Dario ; Moroni, Anna ; Thiel, Gerhard ; Kauferstein, Silke (2016)
Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function.
In: Pflugers Archiv : European journal of physiology, 468 (10)
Artikel, Bibliographie

Greiner, Timo ; Bolduan, Sebastian ; Hertel, Brigitte ; Groß, Christine ; Hamacher, Kay ; Schubert, Ulrich ; Moroni, Anna ; Thiel, Gerhard (2016)
Ion Channel Activity of Vpu Proteins Is Conserved throughout Evolution of HIV-1 and SIV.
In: Viruses, 8 (12)
Artikel, Bibliographie

Hansen, Ulf-Peter ; Rauh, Oliver ; Schroeder, Indra (2016)
A simple recipe for setting up the flux equations of cyclic and linear reaction schemes of ion transport with a high number of states: The arrow scheme.
In: Channels, 10 (2)
doi: 10.1080/19336950.2015.1120391
Artikel, Bibliographie

2015

Roth, Bastian ; Gibhardt, Christine S. ; Becker, Patrick ; Gebhardt, Manuela ; Knoop, Jan ; Fournier, Claudia ; Moroni, Anna ; Thiel, Gerhard (2015)
Low-dose photon irradiation alters cell differentiation via activation of hIK channels.
In: Pflugers Archiv : European journal of physiology, 467 (8)
Artikel, Bibliographie

Chappuis, Charlotte von ; Meckel, Tobias ; Moroni, Anna ; Thiel, Gerhard (2015)
The sorting of a small potassium channel in mammalian cells can be shifted between mitochondria and plasma membrane.
In: Cell calcium, 58 (1)
Artikel, Bibliographie

Carrillo, Lucia ; Cucu, Bayram ; Bandmann, Vera ; Homann, Ulrike ; Hertel, Brigitte ; Hillmer, Stefan ; Thiel, Gerhard ; Bertl, Adam (2015)
High-resolution membrane capacitance measurements for studying endocytosis and exocytosis in yeast.
In: Traffic (Copenhagen, Denmark), 16 (7)
Artikel, Bibliographie

DiFrancesco, Mattia Lorenzo ; Gazzarrini, Sabrina ; Arrigoni, Cristina ; Romani, Giulia ; Thiel, Gerhard ; Moroni, Anna (2015)
Engineering a ca++-sensitive (bio)sensor from the pore-module of a potassium channel.
In: Sensors (Basel, Switzerland), 15 (3)
Artikel, Bibliographie

Thiel, Gerhard ; Greiner, Timo ; Dunigan, David D. ; Moroni, Anna ; Etten, James L. van (2015)
Large dsDNA chloroviruses encode diverse membrane transport proteins.
In: Virology, 479
Artikel, Bibliographie

Bertozzi, Carolyn R. ; Stockwell, Brent R. ; Kubicek, Stefan ; Dickinson, Bryan C. ; Chang, Christopher J. ; Schultz, Carsten ; Silver, Pamela A. ; Gestwicki, Jason E. ; Chiosis, Gabriella ; Chattopadhyay, Amitabha ; Butcher, Rebecca A. ; Park, Seung Bum ; Shoichet, Brian K. ; Flitsch, Sabine L. ; Zhang, Jin ; Liu, David R. ; Ohnishi, Yasuo ; Weerapana, Eranthie ; Williams, Allison H. ; He, Chuan ; Moroni, Anna ; Thiel, Gerhard ; Chang, Young-Tae ; Waldmann, Herbert ; Bogyo, Matthew ; Oddershede, Lene B. ; Christopoulos, Arthur ; Imperiali, Barbara ; Ehrlich, Hermann ; Chen, Xing ; Prescher, Jennifer A. (2015)
Voices of chemical biology.
In: Nature chemical biology, 11 (6)
Artikel, Bibliographie

Cosentino, Cristian ; Alberio, Laura ; Gazzarrini, Sabrina ; Aquila, Marco ; Romano, Edoardo ; Cermenati, Solei ; Zuccolini, Paolo ; Petersen, Jan ; Beltrame, Monica ; Etten, James L. van ; Christie, John M. ; Thiel, Gerhard ; Moroni, Anna (2015)
Optogenetics. Engineering of a light-gated potassium channel.
In: Science (New York, N.Y.), 348 (6235)
Artikel, Bibliographie

Gibhardt, Christine S. ; Roth, Bastian ; Schroeder, Indra ; Fuck, Sebastian ; Becker, Patrick ; Jakob, Burkhard ; Fournier, Claudia ; Moroni, Anna ; Thiel, Gerhard (2015)
X-ray irradiation activates K(+) channels via H2O2 signaling.
In: Scientific reports, 5
Artikel, Bibliographie

Hoffgaard, Franziska ; Kast, S. M. ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2015)
Tectonics of a K(+) channel: The importance of the N-terminus for channel gating.
In: Biochimica et biophysica acta, 1848 (12)
Artikel, Bibliographie

Cucu, Bayram ; Carillo, Lucia ; Degreif, Daniel ; Kohl, Max ; Thiel, Gerhard ; Bertl, Adam (2015)
The role of Clc1p and Chc1p in endocytosis/exocytosis in yeast.
In: Yeast, 32
Artikel, Bibliographie

Schroeder, Indra (2015)
How to resolve microsecond current fluctuations in single ion channels: The power of beta distributions.
In: Channels, 9 (5)
doi: 10.1080/19336950.2015.1083660
Artikel, Bibliographie

2014

Haus, Patricia (2014)
Histondeacetylase 8: Interaktionen und Lokalisation.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Gibhardt, Christine S. (2014)
Radiation induced activation of potassium-channels: The role of ROS and calcium.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Lolicato, Marco ; Bucchi, Annalisa ; Arrigoni, Cristina ; Zucca, Stefano ; Nardini, Marco ; Schroeder, Indra ; Simmons, Katie ; Aquila, Marco ; DiFrancesco, Dario ; Bolognesi, Martino ; Schwede, Frank ; Kashin, Dmitry ; Fishwick, Colin W. G. ; Johnson, A. Peter ; Thiel, Gerhard ; Moroni, Anna (2014)
Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness.
In: Nature chemical biology, 10 (6)
doi: 10.1038/nchembio.1521
Artikel, Bibliographie

Braun, Christian Julian (2014)
Structure/function correlates and protein/lipid interaction of the viral potassium channel KcvNTS.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Bose, Ranjan ; Thiel, Gerhard ; Hamacher, Kay (2014)
Clustering of Giant Virus-DNA Based on Variations in Local Entropy.
In: Viruses, 6 (6)
Artikel, Bibliographie

Braun, Christian J. ; Baer, Tom ; Moroni, Anna ; Thiel, Gerhard (2014)
Pseudo painting/air bubble technique for planar lipid bilayers.
In: Journal of neuroscience methods, 233
Artikel, Bibliographie

Difrancesco, Mattia L. ; Hansen, Ulf-Peter ; Thiel, Gerhard ; Moroni, Anna ; Schroeder, Indra (2014)
Effect of Cytosolic pH on Inward Currents Reveals Structural Characteristics of the Proton Transport Cycle in the Influenza A Protein M2 in Cell-Free Membrane Patches of Xenopus oocytes.
In: PloS one, 9 (9)
Artikel, Bibliographie

Saponaro, Andrea ; Pauleta, Sofia R. ; Cantini, Francesca ; Matzapetakis, Manolis ; Hammann, Christian ; Donadoni, Chiara ; Hu, Lei ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2014)
Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function.
In: Proceedings of the National Academy of Sciences of the United States of America, 11 (40)
Artikel, Bibliographie

Agarkova, Irina ; Hertel, Brigitte ; Zhang, Xinzheng ; Lane, Les ; Tchourbanov, Alexander ; Dunigan, David D. ; Thiel, Gerhard ; Rossmann, Michael G. ; Etten, James L. van (2014)
Dynamic attachment of Chlorovirus PBCV-1 to Chlorella variabilis.
In: Virology, (466-467)
Artikel, Bibliographie

Siotto, Fenja ; Martin, Corinna ; Rauh, Oliver ; Etten, James L. van ; Schroeder, Indra ; Moroni, Anna ; Thiel, Gerhard (2014)
Viruses infecting marine picoplancton encode functional potassium ion channels.
In: Virology, 466-467
Artikel, Bibliographie

2013

Roth, Bastian (2013)
Exposure to sparsely and densely ionizing irradiation results in an immediate activation of K+ channels in A549 cells and in human peripheral blood lymphocytes.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Chappuis, Charlotte von (2013)
Sortierung von Membranproteinen: Einfluss N-terminaler Signale am Beispiel kleiner viraler Kalium-Kanäle.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Smeazzetto, Serena ; Saponaro, Andrea ; Young, Howard S. ; Moncelli, Maria Rosa ; Thiel, Gerhard (2013)
Structure-Function Relation of Phospholamban: Modulation of Channel Activity as a Potential Regulator of SERCA Activity.
In: PloS one, 8 (1)
Artikel, Bibliographie

Cosentino, Cristian ; Di Silvestre, Dario ; Fischer-Schliebs, Elke ; Homann, Ulrike ; De Palma, Antonella ; Comunian, Claudio ; Mauri, Pier Luigi ; Thiel, Gerhard (2013)
Proteomic analysis of Mesembryanthemum crystallinum leaf microsomal fractions finds an imbalance in V-ATPase stoichiometry during the salt-induced transition from C3 to CAM.
In: The Biochemical journal, 450 (2)
Artikel, Bibliographie

Arrigoni, Cristina ; Schroeder, Indra ; Romani, Giulia ; Etten, James L. van ; Thiel, Gerhard ; Moroni, Anna (2013)
The voltage-sensing domain of a phosphatase gates the pore of a potassium channel.
In: The Journal of general physiology, 141 (3)
Artikel, Bibliographie

Schroeder, Indra ; Thiel, Gerhard ; Hansen, Ulf-Peter (2013)
Ca2+ block and flickering both contribute to the negative slope of the IV curve in BK channels.
In: The Journal of general physiology, 141 (4)
Artikel, Bibliographie

Thiel, Gerhard ; Moroni, Anna ; Blanc, Guillaume ; Vanetten, James L. (2013)
Potassium Ion Channels: Could They Have Evolved From Viruses?
In: Plant physiology, 162 (3)
Artikel, Bibliographie

Schroeder, Indra ; Gazzarrini, Sabrina ; Ferrara, Giuseppina ; Thiel, Gerhard ; Hansen, Ulf-Peter ; Moroni, Anna (2013)
Creation of a reactive oxygen species-insensitive Kcv channel.
In: Biochemistry, 52 (18)
Artikel, Bibliographie

Braun, Christian ; Lachnit, Christine ; Becker, Patrick ; Henkes, Leonhard M. ; Arrigoni, Cristina ; Kast, Stefan M. ; Moroni, Anna ; Thiel, Gerhard ; Schroeder, Indra (2013)
Viral potassium channels as a robust model system for studies of membrane-protein interaction.
In: Biochimica et biophysica acta, 1838 (4)
Artikel, Bibliographie

Guthmann, Thomas (2013)
The outer transmembrane domain of the Kesv channel determines its intracellular localization.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Kol, Stefan ; Braun, Christian ; Thiel, Gerhard ; Doyle, Declan A. ; Sundström, Michael ; Gourdon, Pontus ; Nissen, Poul (2013)
Heterologous expression and purification of an active human TRPV3 ion channel.
In: The FEBS journal, 280 (23)
Artikel, Bibliographie

Romani, Giulia ; Piotrowski, Adrianna ; Hillmer, Stefan ; Gurnon, James ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Hertel, Brigitte (2013)
A virus-encoded potassium ion channel is a structural protein in the chlorovirus Paramecium bursaria chlorella virus 1 virion.
In: The Journal of general virology, 94 (Pt 11)
Artikel, Bibliographie

Braun, Christian ; Schroeder, Indra ; Henkes, Leonhard M. ; Arrigoni, Cristina ; Kast, Stefan M. ; Moroni, Anna ; Thiel, Gerhard (2013)
Minimal viral K plus channels as robust model systems for understanding structure/function correlations.
In: European biophysics journal : EBJ, 42 (Suppl. 1)
Artikel, Bibliographie

2012

Wulfmeyer, Timo ; Polzer, Christian ; Hiepler, Gregor ; Hamacher, Kay ; Shoeman, Robert ; Dunigan, David D. ; Etten, James L. van ; Lolicato, Marco ; Moroni, Anna ; Thiel, Gerhard ; Meckel, Tobias (2012)
Structural Organization of DNA in Chlorella Viruses.
In: PLoS ONE, 7 (2)
doi: 10.1371/journal.pone.0030133
Artikel, Bibliographie

Hamacher, Kay ; Greiner, Timo ; Ogata, Hiroyuki ; Etten, James L. van ; Gebhardt, Manuela ; Villarreal, Luis P. ; Cosentino, Cristian ; Moroni, Anna ; Thiel, Gerhard (2012)
Phycodnavirus potassium ion channel proteins question the virus molecular piracy hypothesis.
In: PloS one, 7 (6)
Artikel, Bibliographie

Gebhardt, Manuela ; Henkes, Leonhard M. ; Tayefeh, Sascha ; Hertel, Brigitte ; Greiner, Timo ; Etten, James L. van ; Baumeister, Dirk ; Cosentino, Cristian ; Moroni, Anna ; Kast, Stefan M. ; Thiel, Gerhard (2012)
Relevance of Lysine Snorkeling in the Outer Transmembrane Domain of Small Viral Potassium Ion Channels.
In: Biochemistry, 51 (28)
Artikel, Bibliographie

Sutter, Jens-Uwe ; Denecke, Jürgen ; Thiel, Gerhard (2012)
Synthesis of vesicle cargo determines amplitude of Ca(2+)-sensitive exocytosis.
In: Cell calcium, 52 (3-4)
Artikel, Bibliographie

2011

Bandmann, Vera (2011)
Mechanismen und Kinetik von Exocytose und Endocytose in Pflanzen- und in Hefezellen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Meckel, Tobias ; Semrau, Stefan ; Schmidt, Thomas ; Schaaf, Marcel J. M. (2011)
Robust assessment of protein complex formation in vivo via single-molecule intensity distributions of autofluorescent proteins.
In: Journal of Biomedical Optics, 16 (7)
doi: 10.1117/1.3600002
Artikel, Bibliographie

Gebhardt, Manuela ; Hoffgaard, Franziska ; Hamacher, Kay ; Kast, S. M. ; Moroni, Anna ; Thiel, Gerhard (2011)
Membrane Anchoring and Interaction between Transmembrane Domains are Crucial for K+ Channel Function.
In: The Journal of biological chemistry, 286 (13)
Artikel, Bibliographie

Bolduan, Sebastian ; Votteler, Jörg ; Lodermeyer, Veronika ; Greiner, Timo ; Koppensteiner, Herwig ; Schindler, Michael ; Thiel, Gerhard ; Schubert, Ulrich (2011)
Ion channel activity of HIV-1 Vpu is dispensable for counteraction of CD317.
In: Virology, 416 (1-2)
Artikel, Bibliographie

Thiel, Gerhard ; Baumeister, Dirk ; Schroeder, Indra ; Kast, Stefan M. ; Etten, James L. van ; Moroni, Anna (2011)
Minimal art: or why small viral K(+) channels are good tools for understanding basic structure and function relations.
In: Biochimica et biophysica acta, 1808 (2)
Artikel, Bibliographie

Greiner, Timo ; Ramos, José ; Alvarez, Maria C. ; Gurnon, James R. ; Kang, Ming ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2011)
A Functional HAK/KUP/KT-like Potassium Transporter Encoded by Chlorella Viruses.
In: The Plant journal : for cell and molecular biology, 68 (6)
Artikel, Bibliographie

Kast, Stefan M. ; Kloss, Thomas ; Tayefeh, Sascha ; Thiel, Gerhard (2011)
A minimalist model for ion partitioning and competition in a K+ channel selectivity filter.
In: The Journal of general physiology, 138 (3)
Artikel, Bibliographie

Lolicato, Marco ; Nardini, Marco ; Gazzarrini, Sabrina ; Möller, Stefan ; Bertinetti, Daniela ; Herberg, Friedrich W. ; Bolognesi, Martino ; Martin, Holger ; Fasolini, Marina ; Bertrand, Jay A. ; Arrigoni, Cristina ; Thiel, Gerhard ; Moroni, Anna (2011)
Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels.
In: The Journal of biological chemistry, 286 (52)
Artikel, Bibliographie

2010

Baumeister, Dirk (2010)
Struktur-Funktions-Beziehung viraler Kaliumkanäle : Einfluss der Transmembrandomänen auf die Funktion und Sortierung von Kaliumkanälen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Schwaßmann, Helena J. (2010)
Analyse von Atmungskettenkomplexen aus Organellen von Chlamydomonas reinhardtii und Rattus norvegicus.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Sander, Petra (2010)
Frequency distribution of telomere maintenance mechanisms in soft tissue sarcoma.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Cosentino, C. ; Fischer-Schliebs, E. ; Bertl, A. ; Thiel, Gerhard ; Homann, Ulrike (2010)
Na+/H+ antiporters are differentially regulated in response to NaCl stress in leaves and roots of Mesembryanthemum crystallinum.
In: The New phytologist, 186 (3)
doi: 10.1111/j.1469-8137.2010.03208.x
Artikel, Bibliographie

Liu, Dongfang ; Meckel, Tobias ; Long, Eric O. (2010)
Distinct role of rab27a in granule movement at the plasma membrane and in the cytosol of NK cells.
In: PloS one, 5 (9)
Artikel, Bibliographie

Xu, Xuehua ; Meckel, Tobias ; Brzostowski, Joseph A. ; Yan, Jianshe ; Meier-Schellersheim, Martin ; Jin, Tian (2010)
Coupling mechanism of a GPCR and a heterotrimeric G protein during chemoattractant gradient sensing in Dictyostelium.
In: Science signaling, 3 (141)
Artikel, Bibliographie

Lindhout, Beatrice I. ; Meckel, Tobias ; Zaal, Engelbertus J. van der (2010)
Zinc finger-mediated live cell imaging in Arabidopsis roots.
In: Methods in molecular biology (Clifton, N.J.), 649
Artikel, Bibliographie

Liu, Wanli ; Meckel, Tobias ; Tolar, Pavel ; Sohn, Hae Won ; Pierce, Susan K. (2010)
Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling.
In: Immunity, 32 (6)
Artikel, Bibliographie

Liu, Wanli ; Meckel, Tobias ; Tolar, Pavel ; Sohn, Hae Won ; Pierce, Susan K. (2010)
Antigen affinity discrimination is an intrinsic function of the B cell receptor.
In: The Journal of experimental medicine, 207 (5)
Artikel, Bibliographie

Gall, Lars ; Stan, Razvan C. ; Kress, Alice ; Hertel, Brigitte ; Thiel, Gerhard ; Meckel, Tobias (2010)
Fluorescent detection of fluid phase endocytosis allows for in vivo estimation of endocytic vesicle sizes in plant cells with sub-diffraction accuracy.
In: Traffic (Copenhagen, Denmark), 11 (4)
Artikel, Bibliographie

Liu, Wanli ; Won Sohn, Hae ; Tolar, Pavel ; Meckel, Tobias ; Pierce, Susan K. (2010)
Antigen-induced oligomerization of the B cell receptor is an early target of Fc gamma RIIB inhibition.
In: Journal of immunology (Baltimore, Md. : 1950), 184 (4)
Artikel, Bibliographie

Thiel, Gerhard ; Moroni, Anna ; Dunigan, David ; Etten, James L. van (2010)
Initial Events Associated with Virus PBCV-1 Infection of Chlorella NC64A.
In: Progress in botany. Fortschritte der Botanik, 71 (3)
Artikel, Bibliographie

Bonza, Maria Cristina ; Martin, Holger ; Kang, Ming ; Lewis, Gentry ; Greiner, Timo ; Giacometti, Sonia ; Etten, James L. van ; De Michelis, Maria Ida ; Thiel, Gerhard ; Moroni, Anna (2010)
A functional calcium-transporting ATPase encoded by chlorella viruses.
In: The Journal of general virology, 91 (Pt 10)
Artikel, Bibliographie

Henkel, Michael ; Mitzner, David ; Henklein, Peter ; Meyer-Almes, Franz-Josef ; Moroni, Anna ; Difrancesco, Mattia L. ; Henkes, Leonhard M. ; Kreim, Michael ; Kast, Stefan M. ; Schubert, Ulrich ; Thiel, Gerhard (2010)
The proapoptotic influenza A virus protein PB1-F2 forms a nonselective ion channel.
In: PloS one, 5 (6)
Artikel, Bibliographie

Fischer, Wolfgang B. ; Thiel, Gerhard ; Fink, Rainer H. A. (2010)
Viral membrane proteins.
In: European biophysics journal : EBJ, 39 (7)
Artikel, Bibliographie

Hertel, Brigitte ; Tayefeh, Sascha ; Kloss, Thomas ; Hewing, Jennifer ; Gebhardt, Manuela ; Baumeister, Dirk ; Moroni, Anna ; Thiel, Gerhard ; Kast, Stefan M. (2010)
Salt bridges in the miniature viral channel Kcv are important for function.
In: European biophysics journal : EBJ, 39 (7)
Artikel, Bibliographie

Lüttge, Ulrich ; Kluge, Manfred ; Thiel, Gerhard (2010)
Botanik : die umfassende Biologie der Pflanzen.
Buch, Bibliographie

2009

Brzostowski, Joseph A. ; Meckel, Tobias ; Hong, Jiang ; Chen, Alice ; Jin, Tian (2009)
Imaging protein-protein interactions by Förster resonance energy transfer (FRET) microscopy in live cells.
In: Current Protocols in Protein Science, 56 (1)
doi: 10.1002/0471140864.ps1905s56
Artikel, Bibliographie

Schaaf, Marcel J. M. ; Koopmans, Wiepke J. A. ; Meckel, Tobias ; Noort, John van ; Snaar-Jagalska, B. Ewa ; Schmidt, Thomas S. ; Spaink, Herman P. (2009)
Single-molecule microscopy reveals membrane microdomain organization of cells in a living vertebrate.
In: Biophysical journal, 97 (4)
Artikel, Bibliographie

Liu, Dongfang ; Bryceson, Yenan T. ; Meckel, Tobias ; Vasiliver-Shamis, Gaia ; Dustin, Michael L. ; Long, Eric O. (2009)
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.
In: Immunity, 31 (1)
Artikel, Bibliographie

Chatelain, Franck C. ; Gazzarrini, Sabrina ; Fujiwara, Yuichiro ; Arrigoni, Cristina ; Domigan, Courtney ; Ferrara, Giuseppina ; Pantoja, Carlos ; Thiel, Gerhard ; Moroni, Anna ; Minor, Daniel L. (2009)
Selection of inhibitor-resistant viral potassium channels identifies a selectivity filter site that affects barium and amantadine block.
In: PloS one, 4 (10)
Artikel, Bibliographie

Abenavoli, Alessandra ; DiFrancesco, Mattia Lorenzo ; Schroeder, Indra ; Epimashko, Svetlana ; Gazzarrini, Sabrina ; Hansen, Ulf Peter ; Thiel, Gerhard ; Moroni, Anna (2009)
Fast and slow gating are inherent properties of the pore module of the K+ channel Kcv.
In: The Journal of general physiology, 134 (3)
Artikel, Bibliographie

Greiner, Timo ; Frohns, Florian ; Kang, Ming ; Etten, James L. van ; Käsmann, Anja ; Moroni, Anna ; Hertel, Brigitte ; Thiel, Gerhard (2009)
Chlorella viruses prevent multiple infections by depolarizing the host membrane.
In: The Journal of general virology, 90 (Pt 8)
Artikel, Bibliographie

Gazzarrini, Sabrina ; Kang, Ming ; Abenavoli, Alessandra ; Romani, Giulia ; Olivari, Claudio ; Gaslini, Daniele ; Ferrara, Giuseppina ; Etten, James L. van ; Kreim, Michael ; Kast, Stefan M. ; Thiel, Gerhard ; Moroni, Anna (2009)
Chlorella virus ATCV-1 encodes a functional potassium channel of 82 amino acids.
In: The Biochemical journal, 420 (2)
Artikel, Bibliographie

Tayefeh, Sascha ; Kloss, Thomas ; Kreim, Michael ; Gebhardt, Manuela ; Baumeister, Dirk ; Hertel, Brigitte ; Richter, Christian ; Schwalbe, Harald ; Moroni, Anna ; Thiel, Gerhard ; Kast, Stefan M. (2009)
Model development for the viral Kcv potassium channel.
In: Biophysical journal, 96 (2)
Artikel, Bibliographie

Thiel, Gerhard ; Kreft, Marko ; Zorec, Robert (2009)
Rhythmic kinetics of single fusion and fission in a plant cell protoplast.
In: Annals of the New York Academy of Sciences, 1152
Artikel, Bibliographie

Bonza, M. C. ; Fusca, T. ; Homann, Ulrike ; Thiel, Gerhard ; De Michelis, M. I. (2009)
Intracellular localisation of PPI1 (proton pump interactor, isoform 1), a regulatory protein of the plasma membrane H(+)-ATPase of Arabidopsis thaliana.
In: Plant biology (Stuttgart, Germany), 11 (6)
Artikel, Bibliographie

Tolar, Pavel ; Meckel, Tobias (2009)
Imaging B-cell receptor signaling by single-molecule techniques.
In: Methods in molecular biology (Clifton, N.J.), 571
Artikel, Bibliographie

2008

Agarkova, Irina ; Dunigan, David ; Gurnon, James ; Greiner, Timo ; Barres, Julia ; Thiel, Gerhard ; Etten, James L. van (2008)
Chlorovirus-mediated membrane depolarization of Chlorella alters secondary active transport of solutes.
In: Journal of virology, 82 (24)
Artikel, Bibliographie

Du, Guanghua ; Fischer, Bernd E. ; Voss, Kay-O. ; Becker, Gudrun ; Taucher-Scholz, Gisela ; Kraft, Gerhard ; Thiel, Gerhard (2008)
The absence of an early calcium response to heavy-ion radiation in Mammalian cells.
In: Radiation research, 170 (3)
Artikel, Bibliographie

Balss, Jörg ; Papatheodorou, Panagiotis ; Mehmel, Mario ; Baumeister, Dirk ; Hertel, Brigitte ; Delaroque, Nicolas ; Chatelain, Franck C. ; Minor, Daniel L. ; Etten, James L. van ; Rassow, Joachim ; Moroni, Anna ; Thiel, Gerhard (2008)
Transmembrane domain length of viral K+ channels is a signal for mitochondria targeting.
In: Proceedings of the National Academy of Sciences of the United States of America, 105 (34)
Artikel, Bibliographie

2007

Pagliuca, C. ; Goetze, T. A. ; Wagner, R. ; Thiel, Gerhard ; Moroni, Anna ; Parcej, D. (2007)
Molecular properties of Kcv, a viral-encoded K+ channel.
In: Biochemistry, 46
Artikel, Bibliographie

Meckel, Tobias ; Gall, L. ; Semrau, S. ; Homann, Ulrike ; Thiel, Gerhard (2007)
Guard cells elongate : relationship of volume and surface area during stomatal movement.
In: Biophysical journal, 92
Artikel, Bibliographie

Elter, Astrid ; Hartel, Andreas ; Sieben, Christian ; Hertel, Brigitte ; Fischer-Schliebs, Elke ; Lüttge, Ulrich ; Moroni, Anna ; Thiel, Gerhard (2007)
A plant homolog of animal CLICs generates an ion conductance in heterologous systems.
In: Journal of biological chemistry, 282
Artikel, Bibliographie

Neupaertl, M. ; Meyer, C. ; Woll, I. ; Frohns, Florian ; Kang, Ming ; Etten, James L. van ; Kramer, Detlef ; Hertel, Brigitte ; Moroni, Anna ; Thiel, Gerhard (2007)
Chlorella viruses evoke a rapid release of K+ from host cells during early phase of infection.
In: Virology, 372
Artikel, Bibliographie

Sottocornola, B. ; Gazzarrini, Sabrina ; Olivari, C. ; Romani, G. ; Valbuzzi, P. ; Thiel, Gerhard ; Moroni, Anna (2007)
14-3-3 proteins regulate the K+ channel KAT1 by a dual mode.
In: Plant biology, 10
Artikel, Bibliographie

Tayefeh, Sascha ; Kloss, T. ; Thiel, Gerhard ; Hertel, Brigitte ; Moroni, Anna ; Kast, Stefan Michael (2007)
Molecular dynamics simulation of the cytosolic mouth in Kcv-type potassium channels.
In: Biochemistry, 46
Artikel, Bibliographie

Alpi, A. ; Amrhein, N. ; Bertl, A. ; Blatt, M. R. ; Blumwald, E. ; Cervone, F. ; Dainty, J. ; De Michelis, M. I. ; Epstein, E. ; Galston, A. W. ; Goldsmith, M. H. M. ; Hawes, C. ; Hellwig, R. ; Hetherington, A. ; Hofte, H. ; Juergens, G. ; Leaver, C. J. ; Moroni, A. ; Murphy, A. ; Oparka, K. ; Perata, P. ; Quader, H. ; Rauscher, T. ; Ritzenthaler, C. ; Rivetta, A. ; Robinson, D. G. ; Sanders, D. ; Scheres, B. ; Schumacher, K. ; Sentenac, H. ; Slayman, C. L. ; Soave, C. ; Somerville, C. ; Taiz, L. ; Thiel, Gerhard ; Wagner, R. (2007)
Plant neurobiology: no brain, no gain?
In: Trends in plant science, 12 (4)
doi: 10.1016/j.tplants.2007.03.002
Artikel, Bibliographie

Lindhout, Beatrice I. ; Fransz, Paul ; Tessadori, Federico ; Meckel, Tobias ; Hooykaas, Paul J. J. ; Zaal, Engelbertus J. van der (2007)
Live cell imaging of repetitive DNA sequences via GFP-tagged polydactyl zinc finger proteins.
In: Nucleic acids research, 35 (16)
Artikel, Bibliographie

Homann, Ulrike ; Meckel, Tobias ; Hewing, Jennifer ; Hütt, Marc-Thorsten ; Hurst, Annette C. (2007)
Distinct fluorescent pattern of KAT1::GFP in the plasma membrane of Vicia faba guard cells.
In: European journal of cell biology, 86 (8)
Artikel, Bibliographie

Holtzer, L. ; Meckel, Tobias ; Schmidt, T. (2007)
Nanometric 3D-tracking of individual quantum dots in cells.
In: Appl. Phys. Lett., 90 (5)
Artikel, Bibliographie

Sutter, Jens-Uwe ; Sieben, Christian ; Hartel, Andreas ; Eisenach, Cornelia ; Thiel, Gerhard ; Blatt, Michael R. (2007)
Abscisic acid triggers the endocytosis of the arabidopsis KAT1 K+ channel and its recycling to the plasma membrane.
In: Current biology : CB, 17 (16)
Artikel, Bibliographie

2006

Moroni, Anna ; Thiel, Gerhard (2006)
Flip-flopping salt bridges gate an ion channel.
In: Nature chemical biology, 2
Artikel, Bibliographie

Gazzarrini, Sabrina ; Kang, Ming ; Epimashko, Svetlana ; Etten, James L. van ; Dainty, J. ; Thiel, Gerhard ; Moroni, Anna (2006)
Chlorella virus MT325 encodes water and potassium channels that interact synergistically.
In: Proceedings of the National Academy of the United States of America, 103
Artikel, Bibliographie

Braun, M. ; Foissner, I. ; Lühring, H. ; Schubert, H. ; Thiel, Gerhard (2006)
Characeae : still a valid model system to examine fundamental principles in plants.
In: Progress in botany, 68
Artikel, Bibliographie

Epimashko, Svetlana ; Fischer-Schliebs, Elke ; Christian, A.-L. ; Thiel, Gerhard ; Lüttge, Ulrich (2006)
Na+/H+-transporter, H+-pumps and an aquaporin in light and heavy tonoplast membranes from organic acid and NaCl accumulating vacuoles of the annual facultative CAM plant and halophyte Mesembryanthemum crystallinum L.
In: Planta, 224
Artikel, Bibliographie

Frohns, Florian ; Käsmann, Anja ; Kramer, Detlef ; Schäfer, Britta ; Mehmel, Mario ; Kang, Ming ; Etten, James L. van ; Gazzarrini, Sabrina ; Moroni, Anna ; Thiel, Gerhard (2006)
Potassium ion channels of Chlorella viruses cause rapid depolarization of host cell during infection.
In: Journal of virology, 80
Artikel, Bibliographie

Sottocornola, B. ; Visconti, S. ; Orsi, S. ; Gazzarrini, Sabrina ; Giacometti, S. ; Olivari, C. ; Camoni, L. ; Aducci, P. ; Mauro Marra, M. ; Thiel, Gerhard (2006)
The potassium channel KAT1 is activated by plant and animal 14-3-3 proteins.
In: The journal of biological chemistry, 281
Artikel, Bibliographie

Mikosch, Melanie ; Hurst, Annette ; Hertel, Brigitte ; Homann, Ulrike ; Thiel, Gerhard (2006)
Di-acidic motif is required for efficient transport of the K+ channel KAT1 to the plasma membrane.
In: Plant Physiology, 142
Artikel, Bibliographie

Hertel, Brigitte ; Tayefeh, Sascha ; Mehmel, Mario ; Kast, Stefan Michael ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2006)
Elongation of outer transmembrane domain alters function of miniature K+ channel Kcv.
In: Journal of membrane biology, 210
Artikel, Bibliographie

Gazzarrini, Sabrina ; Abenavoli, Alessandra ; Gradmann, Dietrich ; Thiel, Gerhard ; Moroni, Anna (2006)
Electrokinetics of miniature K+ channel: open-state V sensitivity and inhibition by K+ driving force.
In: The Journal of membrane biology, 214 (1)
Artikel, Bibliographie

2005

Hertel, Brigitte ; Horvath, Ferenc ; Wodala, Barnabas ; Hurst, Annette Christine ; Moroni, Anna ; Thiel, Gerhard (2005)
KAT1 inactivates at sub-millimolar concentrations of external potassium.
In: Journal of experimental botany, 56
Artikel, Bibliographie

Baudenbacher, F. ; Fong, L. E. ; Thiel, Gerhard ; Wacke, M. ; Jazbinsek, V. ; Holzer, J. R. ; Stampfl, A. ; Trontelj, Z. (2005)
Intracellular axial current in Chara corallina reflects the altered kinetics of ions in cytoplasm under the influence of light.
In: Biophysical journal, 88
Artikel, Bibliographie

Meckel, Tobias ; Hurst, Annette Christine ; Thiel, Gerhard ; Homann, Ulrike (2005)
Guard cells undergo constitutive and pressure driven membrane turnover.
In: Protoplasma, 226
Artikel, Bibliographie

2004

Meckel, Tobias (2004)
Endocytosis against the high turgor of guard cells.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Hurst, Annette Christine ; Thiel, Gerhard ; Homann, Ulrike (2004)
Vesicle traffic and plasma membrane transport.
In: Membrane transport in plants / ed. by Michael R. Blatt.- Oxford [u.a.] : Blackwell [u.a.], 2004.- XX, 372 S.- (Annual plant reviews ; 15).- ISBN 1-405-11803-2.- S. 279-293
Artikel, Bibliographie

Epimashko, Svetlana ; Meckel, Tobias ; Fischer-Schliebs, Elke ; Lüttge, Ulrich ; Thiel, Gerhard (2004)
Two functionally different vacuoles for static and dynamic purposes in one plant mesophyll leaf cell.
In: Plant journal, 37 (2)
Artikel, Bibliographie

Hurst, Annette Christine ; Meckel, Tobias ; Tayefeh, Sascha ; Thiel, Gerhard ; Homann, Ulrike (2004)
Trafficking of the plant potassium inward rectifier KAT1 in guard cell protoplasts of Vicia faba.
In: Plant journal, 37 (3)
Artikel, Bibliographie

Meckel, Tobias ; Hurst, Annette Christine ; Thiel, Gerhard ; Homann, Ulrike (2004)
Endocytosis against high turgor : intact guard cells of Vicia faba constitutively endocytose fluorescently labelled plasma membrane and GFP tagged K+-channel KAT1.
In: Plant journal, 39
Artikel, Bibliographie

Kang, Ming ; Graves, M. ; Mehmel, Mario ; Moroni, Anna ; Gazzarrini, Sabrina ; Thiel, Gerhard ; Gurnon, J. ; Etten, James L. van (2004)
Genetic diversity in chlorella viruses flanking kcv, a gene that encodes a potassium ion channel protein.
In: Virology, 326
Artikel, Bibliographie

Kang, Ming ; Moroni, Anna ; Gazzarrini, Sabrina ; DiFrancesco, D. ; Thiel, Gerhard ; Severino, M. ; Etten, James L. van (2004)
Small potassium ion channel protein encoded by chlorella viruses.
In: Proc. Natl. Acad. Sci. U.S.A., 101
Artikel, Bibliographie

Gazzarrini, Sabrina ; Kang, Ming ; Etten, James L. van ; Di Francesco, D. ; Thiel, Gerhard ; Moroni, Anna (2004)
Long-distance interactions within the K+ channel pore highlightened by molecular diversity of viral proteins.
In: Journal of biological chemistry, 279
Artikel, Bibliographie

Moroni, Anna ; Baruscotti, M. ; Thiel, Gerhard
Hrsg.: Bassani, G. (2004)
Ion transport in biological membranes.
In: Encyclopedia of condensed matter physics
Buchkapitel, Bibliographie

Thiel, Gerhard ; Moroni, Anna
Hrsg.: Rossmann, Torsten ; Tropea, Cameron (2004)
Ion channels as functional components in sensors of biomedical information.
In: Bionik : aktuelle Forschungsergebnisse in Natur-, Ingenieur- und Geisteswissenschaft
Buchkapitel, Bibliographie

Schröder, I. ; Huth, T. ; Suitchmezian, V. ; Jarosik, J. ; Schnell, S. ; Hansen, U. P. (2004)
Distributions-per-level: a means of testing level detectors and models of patch-clamp data.
In: The Journal of Membrane Biology, 197 (1)
Artikel, Bibliographie

2003

Hafke, Jens Bodo ; Hafke, Y. ; Smith, J. A. C. ; Lüttge, Ulrich ; Thiel, Gerhard (2003)
Vacuolar malate uptake is mediated by an anion-selective inward rectifier.
In: The plant journal, 35
Artikel, Bibliographie

Mehmel, Mario ; Rothermel, Maike ; Meckel, Tobias ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2003)
Possible function for virus encoded K+ channel Kcv in the replication of chlorella virus PBCV-1.
In: FEBS letters, 552 (1)
Artikel, Bibliographie

Hurst, Annette Christine ; Meckel, Tobias ; Homann, Ulrike ; Thiel, Gerhard (2003)
Unerwartet viel Dynamik : Exo- und Endocytose in Pflanzenzellen.
In: Zellbiologie aktuell, 29 (2)
Artikel, Bibliographie

Gazzarrini, Sabrina ; Severino, Maria ; Lombardi, Mara ; Morandi, Marzia ; DiFrancesco, Dario ; Etten, James L. van ; Thiel, Gerhard ; Moroni, Anna (2003)
The viral potassium channel Kcv: structural and functional features.
In: FEBS letters, 552 (1)
Artikel, Bibliographie

Wacke, M. ; Hütt, M.-T. ; Thiel, Gerhard (2003)
Patterns of membrane excitation in Chara cells in response to periodic stimulation.
In: Nova Acta, (332)
Artikel, Bibliographie

Blatt, M. R. ; Thiel, Gerhard
Hrsg.: Robinson, D. G. (2003)
Molecular components and mechanisms of exocytosis in plants.
In: The Golgi apparatus and the plant secretory pathway
Buchkapitel, Bibliographie

Moroni, Anna ; Etten, James L. van ; Thiel, Gerhard
Hrsg.: Fischer, W. (2003)
Structure and function of a viral encoded K+ channel.
In: Viral membrane proteins : structure, function and drug design
Buchkapitel, Bibliographie

Wacke, M. ; Thiel, Gerhard ; Hütt, Marc-Thorsten (2003)
Ca2+ dynamics during membrane excitation of green alga Chara: model simulations and experimental data.
In: The Journal of membrane biology, 191 (3)
Artikel, Bibliographie

2002

Moroni, Anna ; Viscomi, C. ; Sangiorgio, V. ; Pagliuca, C. ; Meckel, Tobias ; Horvath, F. ; Gazzarrini, Sabrina ; Valbuzzi, P. ; Etten, James L. van ; DiFrancesco, D. ; Thiel, Gerhard (2002)
The short N-terminus is required for functional expression of the virus encoded miniature K+-channel Kcv.
In: FEBS letters, 530 (1-3)
Artikel, Bibliographie

Homann, Ulrike ; Thiel, Gerhard (2002)
The number of K+ channels in the plasma membrane of guard cell protoplasts changes in parallel with the surface area.
In: Proceedings of the National Academy of Sciences of the United States of America, 99
Artikel, Bibliographie

Horvath, F. ; Erdei, L. ; Wodala, B. ; Homann, Ulrike ; Thiel, Gerhard (2002)
K+ outward rectifying channels as targets of phosphatase inhibitor deltamethrin in Vicia faba guard cells.
In: Journal of plant physiology, 159
Artikel, Bibliographie

Thiel, Gerhard ; Wacke, M. ; Foissner, I. (2002)
Ca2+ mobilization from internal stores in electrical membrane excitation in Chara.
In: Progress in botany, 64
Artikel, Bibliographie

Gazzarrini, S. ; Etten, James L. van ; DiFrancesco, D. ; Thiel, Gerhard ; Moroni, Anna (2002)
Voltage-dependence of virus-encoded miniature K+ channel Kcv.
In: The Journal of membrane biology, 187 (1)
Artikel, Bibliographie

Horvarth, F. ; Erdei, L. ; Wodala, B. ; Homann, Ulrike ; Thiel, Gerhard (2002)
Deltametrin rescues rundown of K+ outward rectifiying channels in Vicia faba guard cells.
In: Acta Biol. Szegediensis, (46)
Artikel, Bibliographie

2001

Hafke, Jens Bodo ; Neff, R. ; Hütt, M.-T. ; Lüttge, U. ; Thiel, Gerhard (2001)
Day-to-night variations of cytoplasmic pH in a Crassulacean acid metabolism plant.
In: Protoplasma, 216
Artikel, Bibliographie

Wacke, M. ; Thiel, Gerhard (2001)
Electrically triggered all-or-none Ca2+-liberation during action potential in the giant alga Chara.
In: Journal of general physiology, 118
Artikel, Bibliographie

Bick, I. ; Thiel, Gerhard ; Homann, Ulrike (2001)
Cytochalasin D attenuates the desensitisation of pressure-stimulated vesicle fusion in guard cell protoplasts.
In: European journal of cell biology, 80
Artikel, Bibliographie

Thiel, Gerhard ; Sutter, J. U. ; Homann, Ulrike
Hrsg.: Hawes, C. ; Satiat-Jeunemaitre, B. (2001)
Monitoring exo- and endocytosis in real time with electrophysiological methods.
In: Practical approach series
Buchkapitel, Bibliographie

2000

Moroni, Anna ; Gazzarrini, S. ; Cerana, R. ; Colombo, R. ; Sutter, J. U. ; DiFrancesco, D. ; Gradmann, D. ; Thiel, Gerhard (2000)
Mutation in pore domain uncovers cation- and voltage-sensitive recovery from inactivation in KAT1 channel.
In: Biophysical journal, 78 (4)
Artikel, Bibliographie

Plugge, B. ; Gazzarrini, S. ; Nelson, M. ; Cerana, R. ; Etten, James L. van ; Derst, C. ; DiFrancesco, D. ; Moroni, Anna ; Thiel, Gerhard (2000)
A potassium channel protein encoded by chlorella virus PBCV-1.
In: Science (New York, N.Y.), 287 (5458)
Artikel, Bibliographie

Kubitscheck, U. ; Homann, Ulrike ; Thiel, Gerhard (2000)
Osmotically evoked shrinking of guard-cell protoplasts causes vesicular retrieval of plasma membrane into the cytoplasm.
In: Planta, 210 (3)
Artikel, Bibliographie

Thiel, Gerhard ; Sutter, J. U. ; Homann, Ulrike (2000)
Ca2+-sensitive and Ca2+-insensitive exocytosis in maize coleoptile protoplasts.
In: Pflügers Archiv : European journal of physiology, 439 (3 Supp)
Artikel, Bibliographie

Weise, R. ; Kreft, M. ; Zorec, R. ; Homann, Ulrike ; Thiel, Gerhard (2000)
Transient and permanent fusion of vesicles in Zea mays coleoptile protoplasts measured in the cell-attached configuration.
In: The Journal of membrane biology, 174 (1)
Artikel, Bibliographie

Jazbinsek, V. ; Thiel, Gerhard ; Müller, W. ; Wübbeler, G. ; Trontelj, Z. (2000)
Magnetic detection of injury-induced ionic currents in bean plants.
In: European biophysics journal : EBJ, 29 (7)
Artikel, Bibliographie

Sutter, J. U. ; Homann, Ulrike ; Thiel, Gerhard (2000)
Ca(2)+-stimulated exocytosis in maize coleoptile cells.
In: The Plant cell, 12 (7)
Artikel, Bibliographie

Slibar, M. ; Trontelj, Z. ; Jazbinsek, V. ; Thiel, Gerhard ; Müller, W. (2000)
Magnetic field and electric potential of excited plant cell Chara corallina : calculation and comparison with experiment.
In: Biomag., (96)
Artikel, Bibliographie

Brüdern, A. ; Thiel, Gerhard (2000)
Effect of wall digesting enzymes on physiological state of maize coleoptile cells.
In: Protoplasma, (209)
Artikel, Bibliographie

1999

Homann, Ulrike ; Thiel, Gerhard (1999)
Unitary exocytotic and endocytotic events in guard-cell protoplasts during osmotically driven volume changes.
In: FEBS letters, 460 (3)
Artikel, Bibliographie

Philippar, K. ; Fuchs, I. ; Luthen, H. ; Hoth, S. ; Bauer, C . S. ; Haga, K. ; Thiel, Gerhard ; Ljung, K. ; Sandberg, G. ; Bottger, M. ; Becker, D. ; Hedrich, R. (1999)
Auxin-induced K+ channel expression represents an essential step in coleoptile growth and gravitropism.
In: Proceedings of the National Academy of Sciences of the United States of America, 96 (21)
Artikel, Bibliographie

Biskup, B. ; Gradmann, D. ; Thiel, Gerhard (1999)
Calcium release from InsP3-sensitive internal stores initiates action potential in Chara.
In: FEBS letters, 453 (1-2)
Artikel, Bibliographie

Thiel, Gerhard ; Weise, R. (1999)
Auxin augments K+ inward rectifier in coleoptiles.
In: Planta, 208
Artikel, Bibliographie

White, P. J. ; Biskup, B. ; Elzenga, T. M. ; Homann, Ulrike ; Maathuis, F. J. ; Thiel, Gerhard ; Wissing, F. (1999)
Advanced patch-clamp techniques and single channel analysis.
In: Journal of experimental botany, 50
Artikel, Bibliographie

1998

Moroni, Anna ; Bardella, L. ; Thiel, Gerhard (1998)
The impermeant ion methylammonium blocks K+ and NH4+ currents through KAT1 channel differently: evidence for ion interaction in channel permeation.
In: The Journal of membrane biology, 163 (1)
Artikel, Bibliographie

Thiel, Gerhard ; Dityatev, A. E. (1998)
Transient activity of excitatory Cl- channels in Chara: evidence for quantal release of a gating factor.
In: The Journal of membrane biology, 163 (3)
Artikel, Bibliographie

Thiel, Gerhard ; Battey, N. (1998)
Exocytosis in plants.
In: Plant molecular biology, 38 (1-2)
Artikel, Bibliographie

Plieth, C. ; Sattelmacher, B. ; Hansen, U.-P. ; Thiel, Gerhard (1998)
The action potential in Chara-Ca2+ release from internal stores visualized by Mn2+-induced quenching of fura-dextran.
In: The Plant Journal, 13
Artikel, Bibliographie

Thiel, Gerhard ; Kreft, M. ; Zorec, R. (1998)
Unitary exocytotic and endocytotic events in Zea mays L. coleoptile protoplasts.
In: The Plant Journal, 13
Artikel, Bibliographie

1997

Thiel, Gerhard ; Homann, Ulrike ; Plieth, C. (1997)
Ion channel activity during the action potential in Chara: new insights with new techniques.
In: Journal of experimental botany, 48 (Special issue)
doi: 10.1093/jxb/48.Special_Issue.609
Artikel, Bibliographie

Thiel, Gerhard ; Wolf, A. (1997)
Operation of K+-channels in stomatal movement.
In: Trends in plant science, 2
Artikel, Bibliographie

Thiel, Gerhard ; Brüdern, A. ; Moroni, Anna (1997)
Protein synthesis and Golgi-mediated vesicle traffic is not required to maintain a polarized membrane voltage in the presence of auxin.
In: Protoplasma, 197
Artikel, Bibliographie

1996

Thiel, Gerhard ; Brüdern, A. ; Gradmann, D. (1996)
Small inward rectifying K+ channels in coleoptiles: inhibition by external Ca2+ and function in cell elongation.
In: The Journal of membrane biology, 149 (1)
Artikel, Bibliographie

Trontelj, Z. ; Jazbinsek, V. ; Silbar, M. ; Thiel, Gerhard ; Müller, W. (1996)
Calculated and measured magnetic field and electrical potential of stimulated Chara corallina single cell.
In: Progress in biophysics and molecular biology, 65
Artikel, Bibliographie

1995

Thiel, Gerhard (1995)
Dynamics of chloride and potassium currents during the action potential in Chara studied with action potential clamp.
In: Eur. Biopyhs. J., 24
Artikel, Bibliographie

1994

Homann, Ulrike ; Thiel, Gerhard (1994)
Cl- and K+ channel currents during the action potential in Chara. Simultaneous recording of membrane voltage and patch currents.
In: The Journal of membrane biology, 141 (3)
Artikel, Bibliographie

Blatt, M. R. ; Thiel, Gerhard (1994)
K+ channels of stomatal guard cells: bimodal control of the K+ inward-rectifier evoked by auxin.
In: The Plant journal : for cell and molecular biology, 5 (1)
Artikel, Bibliographie

Thiel, Gerhard (1994)
Redox-state in vacuole and cytoplasm of giant characean algae.
In: Protoplasma
Artikel, Bibliographie

Thiel, Gerhard ; Blatt, M. R. (1994)
Phosphatase antagonist okadaic acid inhibits steady state K+ currents in Vicia faba guard cells.
In: The Plant Journal, 5
Artikel, Bibliographie

Thiel, Gerhard ; Rupnik, M. ; Zorec, R. (1994)
Raising the cytosolic Ca2+ concentration increases membrane capacitance of maize coleoptile protoplasts : evidence for Ca2+ stimulates exocytosis.
In: Planta, 195
Artikel, Bibliographie

Thiel, Gerhard ; Gradmann, D. (1994)
Electrophysiology of stomata.
In: Progress in botany, 55
Artikel, Bibliographie

1993

Gradmann, D. ; Blatt, M. R. ; Thiel, Gerhard (1993)
Electrocoupling of ion transporters in plants.
In: The Journal of membrane biology, 136 (3)
Artikel, Bibliographie

Thiel, Gerhard ; Homann, Ulrike ; Gradmann, D. (1993)
Microscopic elements of electrical excitation in Chara: transient activity of Cl- channels in the plasma membrane.
In: The Journal of membrane biology, 134 (1)
Artikel, Bibliographie

White, P. J. ; Smahel, M. ; Thiel, Gerhard (1993)
Characterization of ion channels from Acetabularia plasma membrane in planar lipid bilayers.
In: The Journal of membrane biology, 133 (2)
Artikel, Bibliographie

Thiel, Gerhard ; Blatt, M. R. ; Fricker, M. D. ; White, I. R. ; Millner, P. (1993)
Modulation of K+ channels in Vicia stomatal guard cells by peptide homologs to the auxin-binding protein C terminus.
In: Proceedings of the National Academy of Sciences of the United States of America, 90 (24)
Artikel, Bibliographie

Blatt, M. R. ; Thiel, Gerhard (1993)
Hormonal control of ion channel gating.
In: Annual review of plant and molecular physiology, 44
Artikel, Bibliographie

1992

Thiel, Gerhard ; MacRobbie, E. A. ; Blatt, M. R. (1992)
Membrane transport in stomatal guard cells: the importance of voltage control.
In: The Journal of membrane biology, 126 (1)
Artikel, Bibliographie

1991

Thiel, Gerhard (1991)
p-CMBS modifies extrafacial sulfhydryl groups at the Chara plasma membrane : activation of Ca2+ influx and inhibition of two different K+ currents.
In: Botanica Acta, 104
Artikel, Bibliographie

Thiel, Gerhard ; Blatt, M. R. (1991)
The mechanisms of ion permeation through K+ channels of stomatal guard cells : voltage-dependent block by Na+.
In: Journal of plant physiology, 138
Artikel, Bibliographie

1990

Thiel, Gerhard ; MacRobbie, E. A. ; Hanke, D. E. (1990)
Raising the intracellular level of inositol 1,4,5-trisphosphate changes plasma membrane ion transport in characean algae.
In: The EMBO journal, 9 (6)
Artikel, Bibliographie

Blatt, M. R. ; Thiel, Gerhard ; Trentham, D. R. (1990)
Reversible inactivation of K+ channels of Vicia stomatal guard cells following the photolysis of caged inositol 1,4,5-trisphosphate.
In: Nature, 346 (6286)
Artikel, Bibliographie

Thiel, Gerhard ; Kirst, G. O. (1990)
Extracellular hexacyanoferrate III inhibits cytoplasmic streaming in the alga Lamprothamnium papulosum.
In: New Phytologist, 115
Artikel, Bibliographie

Thiel, Gerhard ; Tester, M. (1990)
Ferri- and ferrocyanide salts change the current/voltage relations of Chara corallina : no correlation with the transmembrane redox system.
In: Journal of experimental botany, 41
Artikel, Bibliographie

1988

Lynch, J. ; Thiel, Gerhard ; Läuchli, A. (1988)
Effects of salinity on the extensibility and Ca availability in the expanding region of growing barley leaves.
In: Botanica Acta, 101
Artikel, Bibliographie

Thiel, Gerhard ; Kirst, G. O. (1988)
Transmembrane ferricyanide reduction and membrane properties in the euryhaline charophyte Lamprothamnium papulosum.
In: Journal of experimental botany, 39
Artikel, Bibliographie

Thiel, Gerhard ; Lynch, J. ; Läuchli, A. (1988)
Short-term effects of salinity stress on the turgor and elongation of growing barley leaves.
In: Journal of plant physiology, 132
Artikel, Bibliographie

1986

Lass, B. ; Thiel, Gerhard ; Ullrich-Eberius, C. I. (1986)
Electron transport across the plasmalemma of Lemna gibba G1.
In: Planta, (169)
Artikel, Bibliographie

1973

Brinckmann, Enno (1973)
Zur Messung des Membranpotentials und dessen lichtabhängigen Änderungen an Blattzellen höherer Landpflanzen.
Technische Universität Darmstadt
Dissertation, Bibliographie