TU Darmstadt / ULB / TUbiblio

Genes for Membrane Transport Proteins: Not So Rare in Viruses.

Greiner, Timo and Moroni, Anna and Van Etten, James L. and Thiel, Gerhard (2018):
Genes for Membrane Transport Proteins: Not So Rare in Viruses.
In: Viruses, pp. E456, 10, (9), ISSN 1999-4915,
DOI: 10.3390/v10090456,
[Article]

Abstract

Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses. In particular, the evolutionary origin of some of the viral genes is obscure, where other viral proteins have homologs in prokaryotic and eukaryotic organisms. We searched virus genomes in databases looking for transmembrane proteins with possible transport function. This effort led to the detection of 18 different types of putative membrane transport proteins indicating that they are not a rarity in viral genomes. The most abundant proteins are K⁺ channels. Their predicted structures vary between different viruses. With a few exceptions, the viral proteins differed significantly from homologs in their current hosts. In some cases the data provide evidence for a recent gene transfer between host and virus, but in other cases the evidence indicates a more complex evolutionary history.

Item Type: Article
Erschienen: 2018
Creators: Greiner, Timo and Moroni, Anna and Van Etten, James L. and Thiel, Gerhard
Title: Genes for Membrane Transport Proteins: Not So Rare in Viruses.
Language: English
Abstract:

Some viruses have genes encoding proteins with membrane transport functions. It is unknown if these types of proteins are rare or are common in viruses. In particular, the evolutionary origin of some of the viral genes is obscure, where other viral proteins have homologs in prokaryotic and eukaryotic organisms. We searched virus genomes in databases looking for transmembrane proteins with possible transport function. This effort led to the detection of 18 different types of putative membrane transport proteins indicating that they are not a rarity in viral genomes. The most abundant proteins are K⁺ channels. Their predicted structures vary between different viruses. With a few exceptions, the viral proteins differed significantly from homologs in their current hosts. In some cases the data provide evidence for a recent gene transfer between host and virus, but in other cases the evidence indicates a more complex evolutionary history.

Journal or Publication Title: Viruses
Volume: 10
Number: 9
Divisions: 10 Department of Biology
10 Department of Biology > Plant Membrane Biophysics
Date Deposited: 04 Sep 2018 06:21
DOI: 10.3390/v10090456
Identification Number: pmid:30149667
Export:
Suche nach Titel in: TUfind oder in Google

Optionen (nur für Redakteure)

View Item View Item