DiFrancesco, Mattia Lorenzo ; Gazzarrini, Sabrina ; Arrigoni, Cristina ; Romani, Giulia ; Thiel, Gerhard ; Moroni, Anna (2015)
Engineering a ca++-sensitive (bio)sensor from the pore-module of a potassium channel.
In: Sensors (Basel, Switzerland), 15 (3)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Signals recorded at the cell membrane are meaningful indicators of the physiological vs. pathological state of a cell and will become useful diagnostic elements in nanomedicine. In this project we present a coherent strategy for the design and fabrication of a bio-nano-sensor that monitors changes in intracellular cell calcium concentration and allows an easy read out by converting the calcium signal into an electrical current in the range of microampere that can be easily measured by conventional cell electrophysiology apparatus.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2015 |
| Autor(en): | DiFrancesco, Mattia Lorenzo ; Gazzarrini, Sabrina ; Arrigoni, Cristina ; Romani, Giulia ; Thiel, Gerhard ; Moroni, Anna |
| Art des Eintrags: | Bibliographie |
| Titel: | Engineering a ca++-sensitive (bio)sensor from the pore-module of a potassium channel. |
| Sprache: | Englisch |
| Publikationsjahr: | 2015 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Sensors (Basel, Switzerland) |
| Jahrgang/Volume einer Zeitschrift: | 15 |
| (Heft-)Nummer: | 3 |
| Kurzbeschreibung (Abstract): | Signals recorded at the cell membrane are meaningful indicators of the physiological vs. pathological state of a cell and will become useful diagnostic elements in nanomedicine. In this project we present a coherent strategy for the design and fabrication of a bio-nano-sensor that monitors changes in intracellular cell calcium concentration and allows an easy read out by converting the calcium signal into an electrical current in the range of microampere that can be easily measured by conventional cell electrophysiology apparatus. |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Plant Membrane Biophyscis (am 20.12.23 umbenannt in Biologie der Algen und Protozoen) |
| Hinterlegungsdatum: | 10 Mär 2015 09:24 |
| Letzte Änderung: | 10 Mär 2015 09:24 |
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