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A high affinity switch for cAMP in the HCN pacemaker channels.
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Combining in vitro translation with nanodisc technology and functional reconstitution of channels in planar lipid bilayers.
In: Methods in enzymology, 652
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In: Biophysical Journal, 118 (3)
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Chimeric HCN Channels for Studying Camp-Induced Conformational Changes in the C-Linker.
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Saponaro, Andrea ; Cantini, Francesca ; Porro, Alessandro ; Bucchi, Annalisa ; DiFrancesco, Dario ; Maione, Vincenzo ; Donadoni, Chiara ; Introini, Bianca ; Mesirca, Pietro ; Mangoni, Matteo Elia ; Thiel, Gerhard ; Banci, Lucia ; Santoro, Bina ; Moroni, Anna (2018)
A synthetic peptide that prevents cAMP regulation in mammalian Hyperpolarization-activated Cyclic Nucleotide-regulated (HCN) channels.
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