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Initial Events Associated with Virus PBCV-1 Infection of Chlorella NC64A.

Thiel, Gerhard and Moroni, Anna and Dunigan, David and Van Etten, James L. (2010):
Initial Events Associated with Virus PBCV-1 Infection of Chlorella NC64A.
In: Progress in botany. Fortschritte der Botanik, pp. 169-183, 71, (3), ISSN 0340-4773,
[Article]

Abstract

Chlorella viruses (or chloroviruses) are very large, plaque-forming viruses. The viruses are multilayered structures containing a large double-stranded DNA genome, a lipid bilayered membrane, and an outer icosahedral capsid shell. The viruses replicate in certain isolates of the coccal green alga, Chlorella. Sequence analysis of the 330-kbp genome of Paramecium bursaria Chlorella virus 1 (PBCV-1), the prototype of the virus family Phycodnaviridae, reveals <365 protein-encoding genes and 11 tRNA genes. Products of about 40% of these genes resemble proteins of known function, including many that are unexpected for a virus. Among these is a virus-encoded protein, called Kcv, which forms a functional K(+) channel. This chapter focuses on the initial steps in virus infection and provides a plausible role for the function of the viral K(+) channel in lowering the turgor pressure of the host. This step appears to be a prerequisite for delivery of the viral genome into the host.

Item Type: Article
Erschienen: 2010
Creators: Thiel, Gerhard and Moroni, Anna and Dunigan, David and Van Etten, James L.
Title: Initial Events Associated with Virus PBCV-1 Infection of Chlorella NC64A.
Language: English
Abstract:

Chlorella viruses (or chloroviruses) are very large, plaque-forming viruses. The viruses are multilayered structures containing a large double-stranded DNA genome, a lipid bilayered membrane, and an outer icosahedral capsid shell. The viruses replicate in certain isolates of the coccal green alga, Chlorella. Sequence analysis of the 330-kbp genome of Paramecium bursaria Chlorella virus 1 (PBCV-1), the prototype of the virus family Phycodnaviridae, reveals <365 protein-encoding genes and 11 tRNA genes. Products of about 40% of these genes resemble proteins of known function, including many that are unexpected for a virus. Among these is a virus-encoded protein, called Kcv, which forms a functional K(+) channel. This chapter focuses on the initial steps in virus infection and provides a plausible role for the function of the viral K(+) channel in lowering the turgor pressure of the host. This step appears to be a prerequisite for delivery of the viral genome into the host.

Journal or Publication Title: Progress in botany. Fortschritte der Botanik
Volume: 71
Number: 3
Divisions: 10 Department of Biology > Plant Membrane Biophysics
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10 Department of Biology
Date Deposited: 21 Jun 2011 11:54
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