2024

Kolobynina, Ksenia G. (2024)
Novel regulators of chromatin response to DNA damage.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00028085
Dissertation, Erstveröffentlichung, Verlagsversion

Milden-Appel, Manuela ; Paravicini, Markus ; Milden, Jannick P. ; Schüßler, Martin ; Jakoby, Rolf ; Cardoso, M. Cristina (2024)
Uptake of substances into living mammalian cells by microwave induced perturbation of the plasma membrane.
In: Scientific Reports, 14 (1)
doi: 10.1038/s41598-024-71401-7
Artikel, Bibliographie

Arroyo, Maria ; Casas-Delucchi, Corella S. ; Pabba, Maruthi K. ; Prorok, Paulina ; Pradhan, Sunil K. ; Rausch, Cathia ; Lehmkuhl, Anne ; Maiser, Andreas ; Buschbeck, Marcus ; Pasque, Vincent ; Bernstein, Emily ; Luck, Katja ; Cardoso, M. Cristina (2024)
Histone variant macroH2A1 regulates synchronous firing of replication origins in the inactive X chromosome.
In: Nucleic acids research, 52 (9)
doi: 10.1093/nar/gkae734
Artikel, Bibliographie

Ritter, C. ; Lee, J.-Y. ; Pham, M.-T. ; Pabba, M. K. ; Cardoso, M. Cristina ; Bartenschlager, R. ; Rohr, K. (2024)
Multi-detector fusion and Bayesian smoothing for tracking viral and chromatin structures.
In: Medical image analysis, 97
doi: 10.1016/j.media.2024.103227
Artikel, Bibliographie

Pabba, Maruthi K. ; Meyer, Janis ; Celikay, Kerem ; Schermelleh, Lothar ; Rohr, Karl ; Cardoso, M. Cristina (2024)
DNA choreography: correlating mobility and organization of DNA across different resolutions from loops to chromosomes.
In: Histochemistry and cell biology, 162 (2)
doi: 10.1007/s00418-024-02285-x
Artikel, Bibliographie

Pradhan, Sunil Kumar ; Lozoya, Teresa ; Prorok, Paulina ; Yuan, Yue ; Lehmkuhl, Anne ; Zhang, Peng ; Cardoso, M. Cristina (2024)
Developmental changes in genome replication progression in pluripotent versus differentiated human cells.
In: Genes, 15 (3)
doi: 10.3390/genes15030305
Artikel, Bibliographie

Schmidt, Annika ; Zhang, Hui ; Schmitt, Stephanie ; Rausch, Cathia ; Popp, Oliver ; Chen, Jiaxuan ; Cmarko, Dusan ; Butter, Falk ; Dittmar, Gunnar ; Lermyte, Frederik ; Cardoso, M. Cristina (2024)
The proteomic composition and organization of constitutive heterochromatin in mouse tissues.
In: Cells, 13 (2)
doi: 10.3390/cells13020139
Artikel, Bibliographie

Prorok, Paulina ; Wolf, Eva ; Cardoso, M. Cristina (2024)
Timeless-Tipin interactions with MCM and RPA mediate DNA replication stress response.
In: Frontiers in cell and developmental biology, 12
doi: 10.3389/fcell.2024.1346534
Artikel, Bibliographie

2023

Zhang, Hui ; Qin, Weihua ; Romero, Hector ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2023)
Heterochromatin organization and phase separation.
In: Nucleus (Austin, Tex.), 14 (1)
doi: 10.1080/19491034.2022.2159142
Artikel, Bibliographie

Quartieri, Martina (2023)
Developing a Protocol for In Vitro Characterization of Circulating Cancer Stem Cell-like Cells.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00026346
Dissertation, Erstveröffentlichung, Verlagsversion

Pabba, Maruthi Kumar ; Ritter, Christian ; Chagin, Vadim O. ; Meyer, Janis ; Celikay, Kerem ; Stear, Jeffrey H. ; Loerke, Dinah ; Kolobynina, Ksenia ; Prorok, Paulina ; Schmid, Alice Kristin ; Leonhardt, Heinrich ; Rohr, Karl ; Cardoso, M. Cristina (2023)
Replisome loading reduces chromatin motion independent of DNA synthesis.
In: eLife, 12
doi: 10.7554/eLife.87572
Artikel, Bibliographie

Mamberti, Stefania (2023)
Interplay of DNA replication, repair and chromatin: structure versus function.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023039
Dissertation, Erstveröffentlichung, Verlagsversion

Amiri, Anahid ; Dietz, Christian ; Rapp, Alexander ; Cardoso, M. Cristina ; Stark, Robert W. (2023)
The cyto-linker and scaffolding protein "plectin" mis-localization leads to softening of cancer cells.
In: Nanoscale, 15 (36)
doi: 10.1039/d3nr02226a
Artikel, Bibliographie

Arroyo, María ; Hastert, Florian D. ; Zhadan, Andreas ; Schelter, Florian ; Zimbelmann, Susanne ; Rausch, Cathia ; Ludwig, Anne K. ; Carell, Thomas ; Cardoso, M. Cristina (2023)
Author Correction: Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
In: Nature communications, 14 (1)
doi: 10.1038/s41467-023-36067-1
Artikel, Bibliographie

Pradhan, Sunil Kumar ; Cardoso, M. Cristina (2023)
Analysis of Cell Cycle and DNA Compaction Dependent Subnuclear Distribution of Histone Marks.
In: HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Auflage: 2nd Edition
doi: 10.1007/978-1-0716-2788-4_15
Buchkapitel, Bibliographie

Schmidt, Annika (2023)
Heterochromatin composition, organization and MeCP2 post-translational modifications.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00022961
Dissertation, Erstveröffentlichung, Verlagsversion

2022

Zhang, Hui ; Romero, Hector ; Schmidt, Annika ; Gagova, Katalina ; Qin, Weihua ; Bertulat, Bianca ; Lehmkuhl, Anne ; Milden, Manuela ; Eck, Malte ; Meckel, Tobias ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2022)
MeCP2-induced heterochromatin organization is driven by oligomerization-based liquid–liquid phase separation and restricted by DNA methylation.
In: Nucleus (Austin, Tex.), 13 (1)
doi: 10.1080/19491034.2021.2024691
Artikel, Bibliographie

Qin, Weihua ; Steinek, Clemens ; Kolobynina, Ksenia ; Forné, Ignasi ; Imhof, Axel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2022)
Probing protein ubiquitination in live cells.
In: Nucleic acids research, 50 (21)
doi: 10.1093/nar/gkac805
Artikel, Bibliographie

Arroyo, María ; Hastert, Florian D. ; Zhadan, Andreas ; Schelter, Florian ; Zimbelmann, Susanne ; Rausch, Cathia ; Ludwig, Anne K. ; Carell, Thomas ; Cardoso, M. Cristina (2022)
Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
In: Nature communications, 13 (1)
doi: 10.1038/s41467-022-32799-8
Artikel, Bibliographie

Schmidt, Annika ; Frei, Jana ; Poetsch, Ansgar ; Chittka, Alexandra ; Zhang, Hui ; Aßmann, Chris ; Lehmkuhl, Anne ; Bauer, Uta-Maria ; Nuber, Ulrike A. ; Cardoso, M. Cristina (2022)
MeCP2 heterochromatin organization is modulated by arginine methylation and serine phosphorylation.
In: Frontiers in cell and developmental biology, 10
doi: 10.3389/fcell.2022.941493
Artikel, Bibliographie

Kolobynina, Ksenia G. ; Rapp, Alexander ; Cardoso, M. Cristina (2022)
Chromatin Ubiquitination Guides DNA Double Strand Break Signaling and Repair.
In: Frontiers in cell and developmental biology, 10
doi: 10.3389/fcell.2022.928113
Artikel, Bibliographie

Mamberti, Stefania ; Pabba, Maruthi K. ; Rapp, Alexander ; Cardoso, M. Cristina ; Scholz, Michael (2022)
The Chromatin Architectural Protein CTCF Is Critical for Cell Survival upon Irradiation-Induced DNA Damage.
In: International journal of molecular sciences, 23 (7)
doi: 10.3390/ijms23073896
Artikel, Bibliographie

Török, Timea (2022)
Proteomic Investigation of Novel Nuclear JAK2 Pathways.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00014460
Dissertation, Erstveröffentlichung, Verlagsversion

Zhang, Hui (2022)
Phase Separation of the Methyl-CpG-Binding Domain (MBD) Protein Family Underlies Heterochromatin Organization.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00020494
Dissertation, Erstveröffentlichung, Verlagsversion

2021

Rausch, Cathia ; Zhang, Peng ; Casas-Delucchi, Corella S. ; Daiß, Julia L. ; Engel, Christoph ; Coster, Gideon ; Hastert, Florian D. ; Weber, Patrick ; Cardoso, M. Cristina (2021)
Cytosine base modifications regulate DNA duplex stability and metabolism.
In: Nucleic acids research, 49 (22)
doi: 10.1093/nar/gkab509
Artikel, Bibliographie

Qin, Weihua ; Stengl, Andreas ; Ugur, Enes ; Leidescher, Susanne ; Ryan, Joel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
HP1β carries an acidic linker domain and requires H3K9me3 for phase separation.
In: Nucleus (Austin, Tex.), 12 (1)
doi: 10.1080/19491034.2021.1889858
Artikel, Bibliographie

Duan, Ningjun ; Arroyo, Maria ; Deng, Wen ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
Visualization and characterization of RNA-protein interactions in living cells.
In: Nucleic acids research, 49 (18)
doi: 10.1093/nar/gkab614
Artikel, Bibliographie

Qin, Weihua ; Ugur, Enes ; Mulholland, Christopher B. ; Bultmann, Sebastian ; Solovei, Irina ; Modic, Miha ; Smets, Martha ; Wierer, Michael ; Forné, Ignasi ; Imhof, Axel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency.
In: Nucleic acids research, 49 (13)
doi: 10.1093/nar/gkab548
Artikel, Bibliographie

Spilger, Roman ; Lee, Ji-Young ; Chagin, Vadim O. ; Schermelleh, Lothar ; Cardoso, M. Cristina ; Bartenschlager, Ralf ; Rohr, Karl (2021)
Deep probabilistic tracking of particles in fluorescence microscopy images.
In: Medical image analysis, 72
doi: 10.1016/j.media.2021.102128
Artikel, Bibliographie

Gnan, Stefano ; Flyamer, Ilya M. ; Klein, Kyle N. ; Castelli, Eleonora ; Rapp, Alexander ; Maiser, Andreas ; Chen, Naiming ; Weber, Patrick ; Enervald, Elin ; Cardoso, M. Cristina ; Bickmore, Wendy A. ; Gilbert, David M. ; Buonomo, Sara C. B. (2021)
Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction.
In: Nature communications, 12 (1)
doi: 10.1038/s41467-021-22899-2
Artikel, Bibliographie

Levone, Brunno R. ; Lenzken, Silvia C. ; Antonaci, Marco ; Maiser, Andreas ; Rapp, Alexander ; Conte, Francesca ; Reber, Stefan ; Mechtersheimer, Jonas ; Ronchi, Antonella E. ; Mühlemann, Oliver ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Ruepp, Marc-David ; Barabino, Silvia M. L. (2021)
FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.
In: The Journal of cell biology, 220 (5)
doi: 10.1083/jcb.202008030
Artikel, Bibliographie

Schneider, Anselm F. L. ; Kithil, Marina ; Cardoso, M. Cristina ; Lehmann, Martin ; Hackenberger, Christian P. R. (2021)
Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives.
In: Nature chemistry, 13 (6)
doi: 10.1038/s41557-021-00661-x
Artikel, Bibliographie

Rausch, Cathia (2021)
Cytosine Base Modifications, DNA Metabolism and Development.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019518
Dissertation, Erstveröffentlichung, Verlagsversion

Prorok, Paulina ; Grin, Inga R. ; Matkarimov, Bakhyt T. ; Ishchenko, Alexander A. ; Laval, Jacques ; Zharkov, Dmitry O. ; Saparbaev, Murat (2021)
Evolutionary origins of DNA repair pathways: role of oxygen catastrophe in the emergence of DNA glycosylases.
In: Cells, 10 (7)
doi: 10.3390/cells10071591
Artikel, Bibliographie

2020

Rausch, Cathia ; Weber, Patrick ; Prorok, Paulina ; Hörl, David ; Maiser, Andreas ; Lehmkuhl, Anne ; Chagin, Vadim O. ; Casas-Delucchi, Corella S. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2020)
Developmental differences in genome replication program and origin activation.
In: Nucleic acids research, 48 (22)
doi: 10.1093/nar/gkaa1124
Artikel, Bibliographie

Cremer, Marion ; Brandstetter, Katharina ; Maiser, Andreas ; Rao, Suhas S. P. ; Schmid, Volker J. ; Guirao-Ortiz, Miguel ; Mitra, Namita ; Mamberti, Stefania ; Klein, Kyle N. ; Gilbert, David M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Aiden, Erez Lieberman ; Harz, Hartmann ; Cremer, Thomas (2020)
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
In: Nature communications, 11 (1)
doi: 10.1038/s41467-020-19876-6
Artikel, Bibliographie

Cremer, Marion ; Brandstetter, Katharina ; Maiser, Andreas ; Rao, Suhas S. P. ; Schmid, Volker J. ; Guirao-Ortiz, Miguel ; Mitra, Namita ; Mamberti, Stefania ; Klein, Kyle N. ; Gilbert, David M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Lieberman Aiden, Erez ; Harz, Hartmann ; Cremer, Thomas (2020)
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
In: Nature Communications, 11 (1)
doi: 10.1038/s41467-020-19876-6
Artikel, Bibliographie

Mamberti, Stefania ; Cardoso, M. Cristina (2020)
Are the processes of DNA replication and DNA repair reading a common structural chromatin unit?
In: Nucleus (Austin, Tex.), 11 (1)
doi: 10.1080/19491034.2020.1744415
Artikel, Bibliographie

Schwach, Jonathan ; Kolobynina, Ksenia ; Brandstetter, Katharina ; Gerlach, Marcus ; Ochtrop, Philipp ; Helma, Jonas ; Hackenberger, Christian P. R. ; Harz, Hartmann ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Stengl, Andreas (2020)
Site-Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy.
In: Chembiochem : a European journal of chemical biology
doi: 10.1002/cbic.202000727
Artikel, Bibliographie

Weichmann, Franziska ; Hett, Robert ; Schepers, Aloys ; Ito-Kureha, Taku ; Flatley, Andrew ; Slama, Kaouthar ; Hastert, Florian D. ; Angstman, Nicholas B. ; Cardoso, M. Cristina ; König, Julian ; Hüttelmaier, Stefan ; Dieterich, Christoph ; Canzar, Stefan ; Helm, Mark ; Heissmeyer, Vigo ; Feederle, Regina ; Meister, Gunter (2020)
Validation strategies for antibodies targeting modified ribonucleotides.
In: RNA, 26 (10)
doi: 10.1261/rna.076026.120
Artikel, Bibliographie

Pavez Lorie, Elizabeth ; Stricker, Nicola ; Plitta-Michalak, Beata ; Chen, I.-Peng ; Volkmer, Beate ; Greinert, Rüdiger ; Jauch, Anna ; Boukamp, Petra ; Rapp, Alexander (2020)
Characterisation of the novel spontaneously immortalized and invasively growing human skin keratinocyte line HaSKpw.
In: Scientific Reports, 10 (1)
doi: 10.1038/s41598-020-71315-0
Artikel, Bibliographie

Rausch, Cathia ; Hastert, Florian D. ; Cardoso, M. Cristina (2020)
DNA modification readers and writers and their interplay.
In: Journal of molecular biology, 432 (6)
doi: 10.1016/j.jmb.2019.12.018
Artikel, Bibliographie

Schneider, Markus ; Trummer, Carina ; Stengl, Andreas ; Zhang, Peng ; Szwagierczak, Aleksandra ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Bauer, Christina ; Antes, Iris (2020)
Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads.
In: PloS one, 15 (2)
doi: 10.1371/journal.pone.0229144
Artikel, Bibliographie

Napolitano, Giuliana ; Tagliaferri, Daniela ; Fusco, Salvatore ; Cirillo, Carmine ; De Martino, Ilaria ; Addeo, Martina ; Mazzone, Pellegrino ; Russo, Nicola Antonino ; Natale, Francesco ; Cardoso, M. Cristina ; De Luca, Luciana ; Lamorte, Daniela ; La Rocca, Francesco ; De Felice, Mario ; Falco, Geppino (2020)
A novel member of Prame family, Gm12794c, counteracts retinoic acid differentiation through the methyltransferase activity of PRC2.
In: Cell death and differentiation, 27 (1)
doi: 10.1038/s41418-019-0359-9
Artikel, Bibliographie

Schmidt, Annika ; Zhang, Hui ; Cardoso, M. Cristina (2020)
MeCP2 and Chromatin Compartmentalization.
In: Cells, 9 (4)
Artikel, Bibliographie

2019

Chagin, Vadim O. ; Reinhart, Britta ; Becker, Annette ; Mortusewicz, Oliver ; Jost, K. Laurence ; Rapp, Alexander ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2019)
Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair.
In: Nucleus (Austin, Tex.), 10 (1)
doi: 10.1080/19491034.2019.1688932
Artikel, Bibliographie

Amiri, Anahid ; Hastert, Florian D. ; Stühn, Lukas ; Dietz, Christian (2019)
Structural Analysis of Healthy and Cancerous Epithelial Breast Type Cells by Nanomechanical Spectroscopy Allows to Obtain Peculiarities of Skeleton and Junctions.
In: Nanoscale Advances
doi: 10.1039/C9NA00021F
Artikel, Bibliographie

Heinz, Kathrin S. ; Cardoso, M. Cristina (2019)
Targeted Manipulation/Repositioning of Subcellular Structures and Molecules.
In: Methods in molecular biology (Clifton, N.J.), 2038
doi: 10.1007/978-1-4939-9674-2_13
Artikel, Bibliographie

Kasper, Marc-André ; Glanz, Maria ; Stengl, Andreas ; Penkert, Martin ; Klenk, Simon ; Sauer, Tom ; Schumacher, Dominik ; Helma, Jonas ; Krause, Eberhard ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Hackenberger, Christian P. R. (2019)
Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations.
In: Angewandte Chemie International Edition, 58 (34)
doi: 10.1002/anie.201814715
Artikel, Bibliographie

Zhang, Yi ; Bertulat, Bianca ; Tencer, Adam H. ; Ren, Xiaojun ; Wright, Gregory M. ; Black, Joshua ; Cardoso, M. Cristina ; Kutateladze, Tatiana G. (2019)
MORC3 Forms Nuclear Condensates through Phase Separation.
In: iScience, 17
doi: 10.1016/j.isci.2019.06.030
Artikel, Bibliographie

Schmidt, Sönke ; Schubler, Martin ; Hessinger, Carolin ; Schuster, Christian ; Bertulat, Bianca ; Kithil, Marina ; Cardoso, M. Cristina ; Jakoby, Rolf (2019)
Microwave Induced Electroporation of Adherent Mammalian Cells at 18 GHz.
In: IEEE Access, 7
doi: 10.1109/ACCESS.2019.2923073
Artikel, Bibliographie

Zhang, Yi ; Klein, Brianna J. ; Cox, Khan L. ; Bertulat, Bianca ; Tencer, Adam H. ; Holden, Michael R. ; Wright, Gregory M. ; Black, Joshua ; Cardoso, M. Cristina ; Poirier, Michael G. ; Kutateladze, Tatiana G. (2019)
Mechanism for autoinhibition and activation of the MORC3 ATPase.
In: Proceedings of the National Academy of Sciences of the United States of America, 116 (13)
doi: 10.1073/pnas.1819524116
Artikel, Bibliographie

Heinz, Kathrin S. ; Rapp, Alexander ; Casas-Delucchi, Corella S. ; Lehmkuhl, Anne ; Romero-Fernández, Ismael ; Sánchez, Antonio ; Krämer, Oliver H. ; Marchal, J. Alberto ; Cardoso, M. Cristina (2019)
DNA replication dynamics of vole genome and its epigenetic regulation.
In: Epigenetics & chromatin, 12 (1)
Artikel, Bibliographie

Weber, Patrick ; Rausch, Cathia ; Scholl, Annina ; Cardoso, M. Cristina (2019)
Repli-FISH (Fluorescence in Situ Hybridization): Application of 3D-(Immuno)-FISH for the Study of DNA Replication Timing of Genetic Repeat Elements.
In: OBM Genetics, 3 (1)
doi: 10.21926/obm.genet.1901062
Artikel, Bibliographie

Hastert, Florian D. (2019)
Characterization of the cancer-associated short isoform of Tet1 in DNA replication.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Kurek, Katarzyna ; Plitta-Michalak, Beata ; Ratajczak, Ewelina (2019)
Reactive oxygen species as potential drivers of the seed aging process.
In: Plants, 8 (6)
doi: 10.3390/plants8060174
Artikel, Bibliographie

2018

Weber, Patrick (2018)
DNA replication dynamics in embryonic stem cells.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Natale, Francesco ; Scholl, Annina ; Rapp, Alexander ; Yu, Wei ; Rausch, Cathia ; Cardoso, M. Cristina (2018)
DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements.
In: Epigenetics & chromatin, 11 (1)
doi: 10.1186/s13072-018-0226-9
Artikel, Bibliographie

Heinz, Kathrin S. ; Casas-Delucchi, Corella S. ; Török, Timea ; Cmarko, Dusan ; Rapp, Alexander ; Raska, Ivan ; Cardoso, M. Cristina (2018)
Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks.
In: Nucleic acids research, 46 (12)
Artikel, Bibliographie

Kind, Barbara ; Wolf, Christine ; Engel, Kerstin ; Rapp, Alexander ; Cardoso, M. Cristina ; Lee-Kirsch, Min Ae (2018)
Single Cell Gel Electrophoresis for the Detection of Genomic Ribonucleotides.
In: Methods in molecular biology (Clifton, N.J.), 1672
Artikel, Bibliographie

Heinz, Kathrin (2018)
Effect of heterochromatin (com)position on DNA replication timing.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

2017

Herce, Henry D. ; Schumacher, Dominik ; Schneider, Anselm F. L. ; Ludwig, Anne K. ; Mann, Florian A. ; Fillies, Marion ; Kasper, Marc-André ; Reinke, Stefan ; Krause, Eberhard ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. (2017)
Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.
In: Nature chemistry, 9 (8)
Artikel, Bibliographie

Zhang, Peng ; Rausch, Cathia ; Hastert, Florian D. ; Boneva, Boyana ; Filatova, Alina ; Patil, Sujit J. ; Nuber, Ulrike A. ; Gao, Yu ; Zhao, Xinyu ; Cardoso, M. Cristina (2017)
Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
In: Nucleic acids research, 45 (12)
Artikel, Bibliographie

Natale, Francesco ; Rapp, Alexander ; Yu, Wei ; Maiser, Andreas ; Harz, Hartmann ; Scholl, Annina ; Grulich, Stephan ; Anton, Tobias ; Hörl, David ; Chen, Wei ; Durante, Marco ; Taucher-Scholz, Gisela ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
Identification of the elementary structural units of the DNA damage response.
In: Nature communications, 8
Artikel, Bibliographie

Erbeldinger, Nadine ; Rapp, Felicitas ; Ktitareva, Svetlana ; Wendel, Philipp ; Bothe, Anna S. ; Dettmering, Till ; Durante, Marco ; Friedrich, Thomas ; Bertulat, Bianca ; Meyer, Stephanie ; Cardoso, M. Cristina ; Hehlgans, Stephanie ; Rödel, Franz ; Fournier, Claudia (2017)
Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber.
In: Frontiers in immunology, 8
Artikel, Bibliographie

Zhang, Peng ; Ludwig, Anne K. ; Hastert, Florian D. ; Rausch, Cathia ; Lehmkuhl, Anne ; Hellmann, Ines ; Smets, Martha ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
L1 retrotransposition is activated by Ten-eleven-translocation protein 1 and repressed by methyl-CpG binding proteins.
In: Nucleus (Austin, Tex.), 8 (5)
Artikel, Bibliographie

Ludwig, A. K. (2017)
The Guardians of the Epigenome - Regulation and Role of Nucleotide Modifications.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Muster, Britta ; Rapp, Alexander ; Cardoso, M. Cristina (2017)
Systematic analysis of DNA damage induction and DNA repair pathway activation by continuous wave visible light laser micro-irradiation.
In: AIMS Genetics, 4 (1)
doi: 10.3934/genet.2017.1.47
Artikel, Bibliographie

Zhang, Peng ; Hastert, Florian D. ; Ludwig, Anne K. ; Breitwieser, Kai ; Hofstätter, Maria ; Cardoso, M. Cristina (2017)
DNA base flipping analytical pipeline, Biology Methods and Protocols.
In: Biology Methods and Protocols, 2 (1)
doi: 10.1093/biomethods/bpx010
Artikel, Bibliographie

Ludwig, Anne K. ; Zhang, Peng ; Hastert, Florian D. ; Meyer, Stephanie ; Rausch, Cathia ; Herce, Henry D. ; Müller, Udo ; Lehmkuhl, Anne ; Hellmann, Ines ; Trummer, Carina ; Storm, Christian ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise.
In: Nucleic acids research, 45 (5)
Artikel, Bibliographie

Reinhart, Marius ; Cardoso, M. Cristina (2017)
A journey through the microscopic ages of DNA replication.
In: Protoplasma, 254 (3)
Artikel, Bibliographie

Scholl, Annina (2017)
Interplay of DNA replication, repair and chromatin under radiation stress.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

2016

Reinhart, Marius Armin (2016)
Replicons: functional elementary units of genome architecture.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Zhang, Peng (2016)
The regulation of Ten-eleven translocation proteins (methylcytosine modifiers) by methyl-CpG binding domain proteins (methylcytosine readers).
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Becker, Annette ; Zhang, Peng ; Allmann, Lena ; Meilinger, Daniela ; Bertulat, Bianca ; Eck, Daniel ; Hofstaetter, Maria ; Bartolomei, Giody ; Hottiger, Michael ; Schreiber, Valerie ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2016)
Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.
In: The Journal of biological chemistry, 291 (10)
Artikel, Bibliographie

Chagin, V. O. ; Casas-Delucchi, C. S. ; Reinhart, M. ; Schermelleh, L. ; Markaki, Y. ; Maiser, A. ; Bolius, J. J. ; Bensimon, A. ; Fillies, M. ; Domaing, P. ; Rozanov, Y. M. ; Leonhardt, H. ; Cardoso, M. Cristina (2016)
4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
In: Nature communications, 7
Artikel, Bibliographie

Gracheva, Ekaterina ; Chitale, Shalaka ; Wilhelm, Thomas ; Rapp, Alexander ; Byrne, Jonathan ; Stadler, Jens ; Medina, Rebeca ; Cardoso, M. Cristina ; Richly, Holger (2016)
ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.
In: The Journal of cell biology, 213 (2)
Artikel, Bibliographie

Wolf, Christine ; Rapp, Alexander ; Berndt, Nicole ; Staroske, Wolfgang ; Schuster, Max ; Dobrick-Mattheuer, Manuela ; Kretschmer, Stefanie ; König, Nadja ; Kurth, Thomas ; Wieczorek, Dagmar ; Kast, Karin ; Cardoso, M. Cristina ; Günther, Claudia ; Lee-Kirsch, Min Ae (2016)
RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA.
In: Nature communications, 7
Artikel, Bibliographie

Ludwig, Anne K. ; Zhang, Peng ; Cardoso, M. Cristina (2016)
Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease.
In: Frontiers in genetics, 7
Artikel, Bibliographie

Martin, Robert M. ; Herce, Henry D. ; Ludwig, Anne K. ; Cardoso, M. Cristina (2016)
Visualization of the Nucleolus in Living Cells with Cell-Penetrating Fluorescent Peptides.
In: Methods in molecular biology (Clifton, N.J.), 1455
Artikel, Bibliographie

Löb, D. ; Lengert, N. ; Chagin, V. O. ; Reinhart, M. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina ; Drossel, B. (2016)
3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression.
In: Nature communications, 7
Artikel, Bibliographie

2015

Lengert, Laurin ; Lengert, Nicor ; Drossel, Barbara ; Cardoso, M. Cristina ; Muster, Britta ; Nowak, Danny ; Rapp, Alexander (2015)
Discrimination of Kinetic Models by a Combination of Microirradiation and Fluorescence Photobleaching.
In: Biophysical journal, 109 (8)
doi: 10.1016/j.bpj.2015.08.031
Artikel, Bibliographie

Rajan, Malini (2015)
Development of biomarkers and their application to the study of chromatin epistate effect on DNA damage and repair.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Yu, Wei (2015)
Genome-wide analysis of DNA damage and repair.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Nischan, Nicole ; Herce, Henry D. ; Natale, Francesco ; Bohlke, Nina ; Budisa, Nediljko ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. (2015)
Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability.
In: Angewandte Chemie (International ed. in English), 54 (6)
Artikel, Bibliographie

Kretschmer, Stefanie ; Wolf, Christine ; König, Nadja ; Staroske, Wolfgang ; Guck, Jochen ; Häusler, Martin ; Luksch, Hella ; Nguyen, Laura A. ; Kim, Baek ; Alexopoulou, Dimitra ; Dahl, Andreas ; Rapp, Alexander ; Cardoso, M. Cristina ; Shevchenko, Anna ; Lee-Kirsch, Min Ae (2015)
SAMHD1 prevents autoimmunity by maintaining genome stability.
In: Annals of the rheumatic diseases, 74 (3)
Artikel, Bibliographie

Helma, Jonas ; Cardoso, M. Cristina ; Muyldermans, Serge ; Leonhardt, Heinrich (2015)
Nanobodies and recombinant binders in cell biology.
In: The Journal of cell biology, 209 (5)
Artikel, Bibliographie

Romero-Fernández, I. ; Casas-Delucchi, C. S. ; Cano-Linares, M. ; Arroyo, M. ; Sánchez, A. ; Cardoso, M. Cristina ; Marchal, J. A. (2015)
Epigenetic modifications in sex heterochromatin of vole rodents.
In: Chromosoma, 124 (3)
Artikel, Bibliographie

Schumacher, Dominik ; Helma, Jonas ; Mann, Florian A. ; Pichler, Garwin ; Natale, Francesco ; Krause, Eberhard ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. ; Leonhardt, Heinrich (2015)
Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.
In: Angewandte Chemie (International ed. in English), 54 (46)
Artikel, Bibliographie

Jost, K. Laurence ; Bertulat, Bianca ; Rapp, Alexander ; Brero, Alessandro ; Hardt, Tanja ; Domaing, Petra ; Gösele, Claudia ; Schulz, Herbert ; Hübner, Norbert ; Cardoso, M. Cristina (2015)
Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood.
In: Epigenetics & chromatin, 8
Artikel, Bibliographie

Martin, Robert M. ; Ter-Avetisyan, Gohar ; Herce, Henry D. ; Ludwig, Anne K. ; Lättig-Tünnemann, Gisela ; Cardoso, M. Cristina (2015)
Principles of protein targeting to the nucleolus.
In: Nucleus (Austin, Tex.), 6 (4)
Artikel, Bibliographie

Rajan, Malini ; Mortusewicz, Oliver ; Rothbauer, Ulrich ; Hastert, Florian D. ; Schmidthals, Katrin ; Rapp, Alexander ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2015)
Generation of an alpaca-derived nanobody recognizing γ-H2AX.
In: FEBS open bio, 5
Artikel, Bibliographie

2014

Muster, Britta (2014)
DNA repair and chromatin.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Dornblut, Carsten ; Quinn, Nadine ; Monajambashi, Shamci ; Prendergast, Lisa ; van Vuuren, Chelly ; Münch, Sandra ; Deng, Wen ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Hoischen, Christian ; Diekmann, Stephan ; Sullivan, Kevin F. (2014)
A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.
In: Open biology, 4
Artikel, Bibliographie

Cazzalini, Ornella ; Sommatis, Sabrina ; Tillhon, Micol ; Dutto, Ilaria ; Bachi, Angela ; Rapp, Alexander ; Nardo, Tiziana ; Scovassi, A. Ivana ; Necchi, Daniela ; Cardoso, M. Cristina ; Stivala, Lucia A. ; Prosperi, Ennio (2014)
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.
In: Nucleic acids research, 42 (13)
Artikel, Bibliographie

Kind, Barbara ; Muster, Britta ; Staroske, Wolfgang ; Herce, Henry D. ; Sachse, René ; Rapp, Alexander ; Schmidt, Franziska ; Koss, Sarah ; Cardoso, M. Cristina ; Lee-Kirsch, Min Ae (2014)
Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutières syndrome.
In: Human molecular genetics, 23 (22)
Artikel, Bibliographie

Sansoni, Viola ; Casas-Delucchi, Corella S. ; Rajan, Malini ; Schmidt, Andreas ; Bönisch, Clemens ; Thomae, Andreas W. ; Staege, Martin S. ; Hake, Sandra B. ; Cardoso, M. Cristina ; Imhof, Axel (2014)
The histone variant H2A.Bbd is enriched at sites of DNA synthesis.
In: Nucleic acids research, 42 (10)
Artikel, Bibliographie

Song, Congdi ; Feodorova, Yana ; Guy, Jacky ; Peichl, Leo ; Jost, Katharina Laurence ; Kimura, Hiroshi ; Cardoso, M. Cristina ; Bird, Adrian ; Leonhardt, Heinrich ; Joffe, Boris ; Solovei, Irina (2014)
DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution.
In: Epigenetics & chromatin, 7
Artikel, Bibliographie

Herce, Henry D. ; Rajan, Malini ; Lättig-Tünnemann, Gisela ; Fillies, Marion ; Cardoso, M. Cristina (2014)
A novel cell permeable DNA replication and repair marker.
In: Nucleus (Austin, Tex.), 5 (6)
Artikel, Bibliographie

Wieneke, Ralph ; Laboria, Noemi ; Rajan, Malini ; Kollmannsperger, Alina ; Natale, Francesco ; Cardoso, M. Cristina ; Tampé, Robert (2014)
Live-cell targeting of His-tagged proteins by multivalent N-nitrilotriacetic acid carrier complexes.
In: Journal of the American Chemical Society, 136 (40)
Artikel, Bibliographie

Herce, Henry D. ; Garcia, Angel E. ; Cardoso, M. Cristina (2014)
Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules.
In: Journal of the American Chemical Society, 136 (50)
Artikel, Bibliographie

Smirnov, E. ; Borkovec, J. ; Kováčik, L. ; Svidenská, S. ; Schröfel, A. ; Skalníková, M. ; Švindrych, Z. ; Křížek, P. ; Ovesný, M. ; Hagen, G. M. ; Juda, P. ; Michalová, K. ; Cardoso, M. Cristina ; Cmarko, D. ; Raška, I. (2014)
Separation of replication and transcription domains in nucleoli.
In: Journal of structural biology, 188 (3)
Artikel, Bibliographie

2013

Hörner, Sebastian ; Fabritz, Sebastian ; Herce, Henry D. ; Avrutina, Olga ; Dietz, Christian ; Stark, Robert W. ; Cardoso, M. Cristina ; Kolmar, Harald (2013)
Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells.
In: Organic & biomolecular chemistry, 11 (14)
Artikel, Bibliographie

Herce, H. D. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina (2013)
New image colocalization coefficient for fluorescence microscopy to quantify (bio-)molecular interactions.
In: Journal of microscopy, 249 (3)
Artikel, Bibliographie

Becker, Annette ; Allmann, Lena ; Hofstätter, Maria ; Casà, Valentina ; Weber, Patrick ; Lehmkuhl, Anne ; Herce, Henry D. ; Cardoso, M. Cristina (2013)
Direct Homo- and Hetero-Interactions of MeCP2 and MBD2.
In: PloS one, 8 (1)
Artikel, Bibliographie

Reinhart, Marius ; Casas-Delucchi, Corella S. ; Cardoso, M. Cristina (2013)
Spatiotemporal visualization of DNA replication dynamics.
In: Methods in molecular biology (Clifton, N.J.), 1042
Artikel, Bibliographie

Herce, Henry D. ; Deng, Wen ; Helma, Jonas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2013)
Visualization and targeted disruption of protein interactions in living cells.
In: Nature communications, 4
Artikel, Bibliographie

Brink, Maartje C. ; Piebes, Diewertje G. E. ; Groote, Marloes L. de ; Luijsterburg, Martijn S. ; Casas-Delucchi, Corella S. ; Driel, Roeland van ; Rots, Marianne G. ; Cardoso, M. Cristina ; Verschure, Pernette J. (2013)
A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.
In: PloS on, 8 (7)
Artikel, Bibliographie

2012

Casas-Delucchi, Corella S. ; Bemmel, Joke G. van ; Haase, Sebastian ; Herce, Henry D. ; Nowak, Danny ; Meilinger, Daniela ; Stear, Jeffrey H. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2012)
Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin.
In: Nucleic acids research, 40 (1)
Artikel, Bibliographie

Cardoso, M. Cristina ; Schneider, Katrin ; Martin, Robert M. ; Leonhardt, Heinrich (2012)
Structure, function and dynamics of nuclear subcompartments.
In: Current opinion in cell biology, 24 (1)
Artikel, Bibliographie

Vasiliou, Sylvia A. ; Ali, Fahad R. ; Haddley, Kate ; Cardoso, M. Cristina ; Bubb, Vivien J. ; Quinn, John P. (2012)
The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro.
In: Addiction biology, 17 (1)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Becker, Annette ; Bolius, Janine J. ; Cardoso, M. Cristina (2012)
Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization.
In: Nucleic acids research, 40 (22)
Artikel, Bibliographie

Jost, K. Laurence ; Bertulat, Bianca ; Cardoso, M. Cristina (2012)
Heterochromatin and gene positioning: inside, outside, any side?
In: Chromosoma, 121 (6)
Artikel, Bibliographie

Bertulat, Bianca ; De Bonis, Maria Luigia ; Della Ragione, Floriana ; Lehmkuhl, Anne ; Milden, Manuela ; Storm, Christian ; Jost, K. Laurence ; Scala, Simona ; Hendrich, Brian ; D'Esposito, Maurizio ; Cardoso, M. Cristina (2012)
MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line.
In: PloS one, 7 (10)
Artikel, Bibliographie

Greinert, R. ; Volkmer, B. ; Henning, S. ; Breitbart, E. W. ; Greulich, K. O. ; Cardoso, M. Cristina ; Rapp, Alexander (2012)
UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.
In: Nucleic acids research, 40 (20)
Artikel, Bibliographie

Eskat, Anja ; Deng, Wen ; Hofmeister, Antje ; Rudolphi, Sven ; Emmerth, Stephan ; Hellwig, Daniela ; Ulbricht, Tobias ; Döring, Volker ; Bancroft, James M. ; McAinsh, Andrew D. ; Cardoso, M. Cristina ; Meraldi, Patrick ; Hoischen, Christian ; Leonhardt, Heinrich ; Diekmann, Stephan (2012)
Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.
In: PloS one, 7 (9)
Artikel, Bibliographie

2011

Jost, K. Laurence (2011)
Relevance of heterochromatin topology in genome silencing during (retro) differentiation.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Stear, Jeffrey H. ; Loerke, Dinah ; Chagin, Vadim ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
DNA replication machinery clamps down on chromatin mobility.
In: European biophysics journal with biophysics letters, 40
Artikel, Bibliographie

Lättig-Tünnemann, G. ; Prinz, M. ; Hoffmann, D. ; Behlke, J. ; Palm-Apergi, C. ; Herce, H. D. ; Cardoso, M. Cristina (2011)
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
In: Nature communications, 2
doi: 10.1038/ncomms1459
Artikel, Bibliographie

Jost, K. Laurence ; Haase, Sebastian ; Smeets, Daniel ; Schrode, Nadine ; Schmiedel, Jörn M. ; Bertulat, Bianca ; Herzel, Hanspeter ; Cremer, Marion ; Cardoso, M. Cristina (2011)
3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming.
In: Nucleic acids research, 39 (17)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Brero, Alessandro ; Rahn, Hans-Peter ; Solovei, Irina ; Wutz, Anton ; Cremer, Thomas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
Histone acetylation controls the inactive X chromosome replication dynamics.
In: Nature communications, 2
Artikel, Bibliographie

Masata, M. ; Juda, P. ; Raska, O. ; Cardoso, M. Cristina ; Rask, I. (2011)
A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
In: Folia Biol (Praha), 57
Artikel, Bibliographie

Frauer, C. ; Hoffmann, T. ; Bultmann, S. ; Casa, V. ; Cardoso, M. Cristina ; Antes, I. ; Leonhart, H. (2011)
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
In: PLoS One, 6
doi: 10.1371/journal.pone.0021306
Artikel, Bibliographie

Agarwal, N. ; Becker, A. ; Jost, K. L. ; Haase, S. ; Thakur, B. K. ; Brero, A. ; Hardt, T. ; Kudo, S. ; Leonhart, H. ; Cardoso, M. Cristina (2011)
MeCP2 Rett mutations affect large scale chromatin organization.
In: Human molecular genetics, 20 (21)
doi: 10.1093/hmg/ddr346.
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Cardoso, M. Cristina (2011)
Epigenetic control of DNA replication dynamics in mammals.
In: Nucleus (Austin, Tex.), 2 (5)
Artikel, Bibliographie

Jost, K. Laurence ; Rottach, Andrea ; Milden, Manuela ; Bertulat, Bianca ; Becker, Annette ; Wolf, Patricia ; Sandoval, Juan ; Petazzi, Paolo ; Huertas, Dori ; Esteller, Manel ; Kremmer, Elisabeth ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies.
In: PloS one, 6 (11)
Artikel, Bibliographie

2010

Martin, Robert M. ; Cardoso, M. Cristina (2010)
Chromatin condensation modulates access and binding of nuclear proteins.
In: The FASEB journal, 24 (4)
doi: 10.1096/fj.08-128959
Artikel, Bibliographie

Baddeley, D. ; Chagin, V. O. ; Schermelleh, L. ; Martin, S. ; Pombo, A. ; Carlton, P. M. ; Gahl, A. ; Domaing, P. ; Birk, U. ; Leonhardt, H. ; Cremer, C. ; Cardoso, M. Cristina (2010)
Measurement of replication structures at the nanometer scale using super-resolution light microscopy.
In: Nucleic acids research, 38 (2)
doi: 10.1093/nar/gkp901
Artikel, Bibliographie

Kirchhofer, A. ; Helma, J. ; Schmidthals, K. ; Frauer, C. ; Cui, S. ; Karcher, A. ; Pellis, M. ; Muyldermans, S. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina ; Leonhardt, H. ; Hopfner, K. P. ; Rothbauer, U. (2010)
Modulation of protein properties in living cells using nanobodies.
In: Nature structural & molecular biology, 17 (1)
doi: 10.1038/nsmb.1727
Artikel, Bibliographie

Chagin, V. O. ; Stear, J. H. ; Cardoso, M. Cristina (2010)
Organization of DNA Replication.
In: Cold Spring Harb Perspect Biol., 2
doi: 10.1101/cshperspect.a000737
Artikel, Bibliographie

Zhu, Y. ; Wu, Z. ; Cardoso, M. Cristina ; Parris, D. S. (2010)
Processing of Lagging-Strand Intermediates In Vitro by Herpes Simplex Virus Type 1 DNA Polymerase.
In: Journal of Virology, 84 (15)
doi: 10.1128/JVI.01875-09
Artikel, Bibliographie

2009

Ersoy, Ilker ; Bunyak, Filiz ; Chagin, Vadim ; Cardoso, M. Cristina ; Palaniappan, Kannappan (2009)
Segmentation and Classification of Cell Cycle Phases in Fluorescence Imaging.
In: Lecture notes in computer science, 5762
Artikel, Bibliographie

Ter-Avetisyan, Gohar ; Tünnemann, Gisela ; Nowak, Danny ; Nitschke, Matthias ; Herrmann, Andreas ; Drab, Marek ; Cardoso, M. Cristina (2009)
Cell entry of arginine-rich peptides is independent of endocytosis.
In: The Journal of biological chemistry, 284 (6)
Artikel, Bibliographie

Liska, Frantisek ; Gosele, Claudia ; Rivkin, Eugene ; Tres, Laura ; Cardoso, M. Cristina ; Domaing, Petra ; Krejcí, Eliska ; Snajdr, Pavel ; Lee-Kirsch, Min Ae ; Rooij, Dirk G. de ; Kren, Vladimír ; Krenová, Drahomíra ; Kierszenbaum, Abraham L. ; Hubner, Norbert (2009)
Rat hd mutation reveals an essential role of centrobin in spermatid head shaping and assembly of the head-tail coupling apparatus.
In: Biology of reproduction, 81 (6)
Artikel, Bibliographie

Ciobanasu, Corina ; Harms, Enno ; Tünnemann, Gisela ; Cardoso, M. Cristina ; Kubitscheck, Ulrich (2009)
Cell-penetrating HIV1 TAT peptides float on model lipid bilayers.
In: Biochemistry, 48 (22)
Artikel, Bibliographie

Tünnemann, G. ; Cardoso, M. Cristina (2009)
Cell-Penetrating Peptides Uptake, Toxicity, and Applications.
In: Membrane-Active Peptides: methods and results on structure and function.- Ed. M. Castanho
Buchkapitel, Bibliographie

Grigaravicius, P. ; Rapp, A. ; Greulich, K. O. (2009)
A direct view by immunofluorescent comet assay (IFCA) of DNA damage induced by nicking and cutting enzymes, ionizing 137Cs radiation, UV-A laser microbeam irradiation and the radiomimetic drug bleomycin.
In: Mutagenesis, 24 (2)
doi: 10.1093/mutage/gen071
Artikel, Bibliographie

Zainol, M. ; Stoute, J. ; Almeida, G. M. ; Rapp, A. ; Bowman, K. J. ; Jones, G. D. D. (2009)
Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair.
In: Nucleic acids research, 37 (22)
doi: 10.1093/nar/gkp826
Artikel, Bibliographie

2008

Zolghadr, Kourosh ; Mortusewicz, Oliver ; Rothbauer, Ulrich ; Kleinhans, Regina ; Goehler, Heike ; Wanker, Erich E. ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2008)
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells.
In: Molecular & cellular proteomics : MCP, 7 (11)
Artikel, Bibliographie

Mortusewicz, Oliver ; Roth, Wera ; Li, Na ; Cardoso, M. Cristina ; Meisterernst, Michael ; Leonhardt, Heinrich (2008)
Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites.
In: The Journal of cell biology, 183 (5)
Artikel, Bibliographie

Rottach, Andrea ; Kremmer, Elisabeth ; Nowak, Danny ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins.
In: Hybridoma, 27 (5)
Artikel, Bibliographie

Mortusewicz, Oliver ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites.
In: Journal of cellular biochemistry, 104 (5)
Artikel, Bibliographie

Görisch, Sabine M. ; Sporbert, Anje ; Stear, Jeffrey H. ; Grunewald, Ingrid ; Nowak, Danny ; Warbrick, Emma ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis.
In: Cell cycle (Georgetown, Tex.), 7 (13)
Artikel, Bibliographie

Nitschke, Matthias ; Korte, Thomas ; Tielesch, Claudia ; Ter-Avetisyan, Gohar ; Tünnemann, Gisela ; Cardoso, M. Cristina ; Veit, Michael ; Herrmann, Andreas (2008)
Equine arteritis virus is delivered to an acidic compartment of host cells via clathrin-dependent endocytosis.
In: Virology, 377 (2)
Artikel, Bibliographie

Rottach, Andrea ; Kremmer, Elisabeth ; Nowak, Danny ; Boisguerin, Prisca ; Volkmer, Rudolf ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Rothbauer, Ulrich (2008)
Generation and characterization of a rat monoclonal antibody specific for PCNA.
In: Hybridoma, 27 (2)
Artikel, Bibliographie

Schermelleh, Lothar ; Carlton, Peter M. ; Haase, Sebastian ; Shao, Lin ; Winoto, Lukman ; Kner, Peter ; Burke, Brian ; Cardoso, M. Cristina ; Agard, David A. ; Gustafsson, Mats G. L. ; Leonhardt, Heinrich ; Sedat, John W. (2008)
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy.
In: Science, 320 (5881)
Artikel, Bibliographie

Grünwald, David ; Martin, Robert M. ; Buschmann, Volker ; Bazett-Jones, David P. ; Leonhardt, Heinrich ; Kubitscheck, Ulrich ; Cardoso, M. Cristina (2008)
Probing intranuclear environments at the single-molecule level.
In: Biophysical journal, 94 (7)
Artikel, Bibliographie

Gupta, Shashank ; Höpner, Sabine ; Rupp, Bernd ; Günther, Sebastian ; Dickhaut, Katharina ; Agarwal, Noopur ; Cardoso, M. Cristina ; Kühne, Ronald ; Wiesmüller, Karl-Heinz ; Jung, Günther ; Falk, Kirsten ; Rötzschke, Olaf (2008)
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
In: PloS one, 3 (3)
Artikel, Bibliographie

Rothbauer, Ulrich ; Zolghadr, Kourosh ; Muyldermans, Serge ; Schepers, Aloys ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2008)
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins.
In: Molecular & cellular proteomics : MCP, 7 (2)
Artikel, Bibliographie

Shumaker, Dale K. ; Solimando, Liliana ; Sengupta, Kaushik ; Shimi, Takeshi ; Adam, Stephen A. ; Grunwald, Antje ; Strelkov, Sergei V. ; Aebi, Ueli ; Cardoso, M. Cristina ; Goldman, Robert D. (2008)
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication.
In: The Journal of cell biology, 181 (2)
Artikel, Bibliographie

Tünnemann, Gisela ; Ter-Avetisyan, Gohar ; Martin, Robert M. ; Stöckl, Martin ; Herrmann, Andreas ; Cardoso, M. Cristina (2008)
Live-cell analysis of cell penetration ability and toxicity of oligo-arginines.
In: Journal of peptide science : an official publication of the European Peptide Society, 14 (4)
Artikel, Bibliographie

2007

Agarwal, Noopur ; Hardt, Tanja ; Brero, Alessandro ; Nowak, Danny ; Rothbauer, Ulrich ; Becker, Annette ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation.
In: Nucleic acids research, 35 (16)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
Distribution of DNA replication proteins in Drosophila cells.
In: BMC cell biology, 8
Artikel, Bibliographie

Martin, Robert M. ; Tünnemann, Gisela ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
Nucleolar marker for living cells.
In: Histochemistry and cell biology, 127 (3)
Artikel, Bibliographie

Martin, Robert M. ; Görisch, Sabine M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
An unexpected link between energy metabolism, calcium, chromatin condensation and cell cycle.
In: Cell cycle (Georgetown, Tex.), 6 (19)
Artikel, Bibliographie

Schermelleh, Lothar ; Haemmer, Andrea ; Spada, Fabio ; Rösing, Nicole ; Meilinger, Daniela ; Rothbauer, Ulrich ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2007)
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.
In: Nucleic acids research, 35 (13)
Artikel, Bibliographie

Tünnemann, Gisela ; Karczewski, Peter ; Haase, Hannelore ; Cardoso, M. Cristina ; Morano, Ingo (2007)
Modulation of muscle contraction by a cell-permeable peptide.
In: Journal of molecular medicine, 85 (12)
Artikel, Bibliographie

Vietinghoff, Sibylle von ; Tünnemann, Gisela ; Eulenberg, Claudia ; Wellner, Maren ; Cristina Cardoso, M. ; Luft, Friedrich C. ; Kettritz, Ralph (2007)
NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils.
In: Blood, 109 (10)
Artikel, Bibliographie

2006

Brero, A. ; Leonhardt, H. ; Cardoso, M. Cristina (2006)
Replication and translation of epigenetic information.
In: Current topics in microbiology and immunology, 301
Artikel, Bibliographie

Grünwald, David ; Hoekstra, Andreas ; Dange, Thomas ; Buschmann, Volker ; Kubitscheck, Ulrich (2006)
Direct observation of single protein molecules in aqueous solution.
In: Chemphyschem : a European journal of chemical physics and physical chemistry, 7 (4)
Artikel, Bibliographie

Haase, Hannelore ; Dobbernack, Gisela ; Tünnemann, Gisela ; Karczewski, Peter ; Cardoso, M. Cristina ; Petzhold, Daria ; Schlegel, Wolfgang-Peter ; Lutter, Steffen ; Pierschalek, Petra ; Behlke, Joachim ; Morano, Ingo (2006)
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (7)
Artikel, Bibliographie

Mortusewicz, Oliver ; Rothbauer, Ulrich ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2006)
Differential recruitment of DNA Ligase I and III to DNA repair sites.
In: Nucleic acids research, 34 (12)
Artikel, Bibliographie

Rothbauer, Ulrich ; Zolghadr, Kourosh ; Tillib, Sergei ; Nowak, Danny ; Schermelleh, Lothar ; Gahl, Anja ; Backmann, Natalija ; Conrath, Katja ; Muyldermans, Serge ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2006)
Targeting and tracing antigens in live cells with fluorescent nanobodies.
In: Nature methods, 3 (11)
Artikel, Bibliographie

Perucca, Paola ; Cazzalini, Ornella ; Mortusewicz, Oliver ; Necchi, Daniela ; Savio, Monica ; Nardo, Tiziana ; Stivala, Lucia A. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Prosperi, Ennio (2006)
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen.
In: Journal of cell science, 119 (Pt 8)
Artikel, Bibliographie

Tünnemann, Gisela ; Martin, Robert M. ; Haupt, Simone ; Patsch, Christoph ; Edenhofer, Frank ; Cardoso, M. Cristina (2006)
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (11)
Artikel, Bibliographie

Weidtkamp-Peters, Stefanie ; Rahn, Hans-Peter ; Cardoso, M. Cristina ; Hemmerich, Peter (2006)
Replication of centromeric heterochromatin in mouse fibroblasts takes place in early, middle, and late S phase.
In: Histochemistry and cell biology, 125 (1-2)
Artikel, Bibliographie

2005

Brero, Alessandro ; Easwaran, Hariharan P. ; Nowak, Danny ; Grunewald, Ingrid ; Cremer, Thomas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation.
In: The Journal of cell biology, 169 (5)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
Cell cycle markers for live cell analyses.
In: Cell cycle (Georgetown, Tex.), 4 (3)
Artikel, Bibliographie

Görisch, Sabine M. ; Wachsmuth, Malte ; Tóth, Katalin Fejes ; Lichter, Peter ; Rippe, Karsten (2005)
Histone acetylation increases chromatin accessibility.
In: Journal of cell science, 118 (Pt 24)
Artikel, Bibliographie

Görisch, Sabine M. ; Lichter, Peter ; Rippe, Karsten (2005)
Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments.
In: Histochemistry and cell biology, 123 (3)
Artikel, Bibliographie

Grünwald, D. ; Cardoso, M. Cristina ; Leonhardt, H. ; Buschmann, V. (2005)
Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS).
In: Current pharmaceutical biotechnology, 6 (5)
Artikel, Bibliographie

Grohmann, Maik ; Spada, Fabio ; Schermelleh, Lothar ; Alenina, Natalia ; Bader, Michael ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming.
In: BMC developmental biology, 5
Artikel, Bibliographie

Jambor de Sousa, Ulrike L. ; Koss, Michael D. ; Fillies, Marion ; Gahl, Anja ; Scheeder, Martin R L. ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Geary, Nori ; Langhans, Wolfgang ; Leonhardt, Monika (2005)
CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells.
In: Biochemical and biophysical research communications, 338 (2)
Artikel, Bibliographie

Martin, Robert M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
DNA labeling in living cells.
In: Cytometry. Part A, 67 (1)
Artikel, Bibliographie

Mortusewicz, Oliver ; Schermelleh, Lothar ; Walter, Joachim ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Recruitment of DNA methyltransferase I to DNA repair sites.
In: Proceedings of the National Academy of Sciences of the United States of America, 102 (25)
Artikel, Bibliographie

Richter, Karsten ; Reichenzeller, Michaela ; Görisch, Sabine M. ; Schmidt, Ute ; Scheuermann, Markus O. ; Herrmann, Harald ; Lichter, Peter (2005)
Characterization of a nuclear compartment shared by nuclear bodies applying ectopic protein expression and correlative light and electron microscopy.
In: Experimental cell research, 303 (1)
Artikel, Bibliographie

Sporbert, Anje ; Domaing, Petra ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins.
In: Nucleic acids research, 33 (11)
Artikel, Bibliographie

Schermelleh, Lothar ; Spada, Fabio ; Easwaran, Hariharan P. ; Zolghadr, Kourosh ; Margot, Jean B. ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Trapped in action: direct visualization of DNA methyltransferase activity in living cells.
In: Nature methods, 2 (10)
Artikel, Bibliographie

2004

Angus, Steven P. ; Mayhew, Christopher N. ; Solomon, David A. ; Braden, Wesley A. ; Markey, Michael P. ; Okuno, Yukiko ; Cardoso, M. Cristina ; Gilbert, David M. ; Knudsen, Erik S. (2004)
RB reversibly inhibits DNA replication via two temporally distinct mechanisms.
In: Molecular and cellular biology, 24 (12)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Schermelleh, Lothar ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2004)
Replication-independent chromatin loading of Dnmt1 during G2 and M phases.
In: EMBO reports, 5 (12)
Artikel, Bibliographie

Sadoni, Nicolas ; Cardoso, M. Cristina ; Stelzer, Ernst H. K. ; Leonhardt, Heinrich ; Zink, Daniele (2004)
Stable chromosomal units determine the spatial and temporal organization of DNA replication.
In: Journal of cell science, 117 (Pt 22)
Artikel, Bibliographie

Solomon, David A. ; Cardoso, M. Cristina ; Knudsen, Erik S. (2004)
Dynamic targeting of the replication machinery to sites of DNA damage.
In: The Journal of cell biology, 166 (4)
Artikel, Bibliographie

Gaudet, F. ; Rideout, W. M. 3rd. ; Meissner, A. ; Dausman, J. ; Leonhardt, H. ; Jaenisch, R. (2004)
Dnmt1 Expression in Pre- and Postimplantation Embryogenesis and the Maintenance of IAP Silencing.
In: Mol. Cell Biol., 24
Artikel, Bibliographie

2003

Choi, Mira ; Rolle, Susanne ; Wellner, Maren ; Cardoso, M. Cristina ; Scheidereit, Claus ; Luft, Friedrich C. ; Kettritz, Ralph (2003)
Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
In: Blood, 102 (6)
Artikel, Bibliographie

Eden, Amir ; Gaudet, François ; Waghmare, Alpana ; Jaenisch, Rudolf (2003)
Chromosomal instability and tumors promoted by DNA hypomethylation.
In: Science (New York, N.Y.), 300 (5618)
Artikel, Bibliographie

Gaudet, François ; Hodgson, J. Graeme ; Eden, Amir ; Jackson-Grusby, Laurie ; Dausman, Jessica ; Gray, Joe W. ; Leonhardt, Heinrich ; Jaenisch, Rudolf (2003)
Induction of tumors in mice by genomic hypomethylation.
In: Science (New York, N.Y.), 300 (5618)
Artikel, Bibliographie

Görisch, Sabine M. ; Richter, Karsten ; Scheuermann, Markus O. ; Herrmann, Harald ; Lichter, Peter (2003)
Diffusion-limited compartmentalization of mammalian cell nuclei assessed by microinjected macromolecules.
In: Experimental cell research, 289 (2)
Artikel, Bibliographie

Margot, Jean B. ; Ehrenhofer-Murray, Ann E. ; Leonhardt, Heinrich (2003)
Interactions within the mammalian DNA methyltransferase family.
In: BMC molecular biology, 4
Artikel, Bibliographie

Cardoso, M. Cristina (2003)
Law and order in the nucleus.
In: Zellbiologie aktuell, 29 (3)
Artikel, Bibliographie

2002

Biniszkiewicz, Detlev ; Gribnau, Joost ; Ramsahoye, Bernard ; Gaudet, François ; Eggan, Kevin ; Humpherys, David ; Mastrangelo, Mary-Ann ; Jun, Zhan ; Walter, Jörn ; Jaenisch, Rudolf (2002)
Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.
In: Molecular and cellular biology, 22 (7)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, Heinrich (2002)
Protein transduction: a novel tool for tissue regeneration.
In: Biological chemistry, 383 (10)
Artikel, Bibliographie

Derer, Wolfgang ; Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2002)
A novel approach to induce cell cycle reentry in terminally differentiated muscle cells.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 16 (1)
Artikel, Bibliographie

Quensel, Christina ; Krämer, Jochen ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2002)
Smoothelin contains a novel actin cytoskeleton localization sequence with similarity to troponin T.
In: Journal of cellular biochemistry, 85 (2)
Artikel, Bibliographie

Sporbert, Anje ; Gahl, Anja ; Ankerhold, Richard ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2002)
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
In: Molecular cell, 10 (6)
Artikel, Bibliographie

2001

Krämer, Jochen ; Quensel, Christina ; Meding, J. ; Cardoso, M. Cristina ; Leonhardt, H. (2001)
Identification and characterization of novel smoothelin isoforms in vascular smooth muscle.
In: Journal of vascular research, 38 (2)
Artikel, Bibliographie

Margot, J. B. ; Cardoso, M. Cristina ; Leonhardt, H. (2001)
Mammalian DNA methyltransferases show different subnuclear distributions.
In: Journal of cellular biochemistry, 83 (3)
Artikel, Bibliographie

2000

Aguirre-Arteta, A. M. ; Grunewald, I. ; Cardoso, M. Cristina ; Leonhardt, H. (2000)
Expression of an alternative Dnmt1 isoform during muscle differentiation.
In: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 11 (10)
Artikel, Bibliographie

Leonhardt, H. ; Cardoso, M. Cristina (2000)
DNA methylation, nuclear structure, gene expression and cancer.
In: Journal of cellular biochemistry, 79 (S35)
Artikel, Bibliographie

Leonhardt, H. ; Rahn, H. P. ; Weinzierl, P. ; Sporbert, A. ; Cremer, T. ; Zink, D. ; Cardoso, M. Cristina (2000)
Dynamics of DNA replication factories in living cells.
In: The Journal of cell biology, 149 (2)
Artikel, Bibliographie

Leonhardt, H. ; Sporbert, A. ; Cardoso, M. Cristina (2000)
Targeting regulatory factors to intranuclear replication sites.
In: Critical reviews in eukaryotic gene expression, 10 (2)
Artikel, Bibliographie

Margot, J. B. ; Aguirre-Arteta, A. M. ; Di Giacco, B. V. ; Pradhan, S. ; Roberts, R. J. ; Cardoso, M. Cristina ; Leonhardt, H. (2000)
Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure.
In: Journal of molecular biology, 297 (2)
Artikel, Bibliographie

1999

Cardoso, M. Cristina ; Sporbert, A. ; Leonhardt, H. (1999)
Structure and function in the nucleus: subnuclear trafficking of DNA replication factors.
In: Journal of cellular biochemistry, 75 (S32)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. (1999)
DNA methyltransferase is actively retained in the cytoplasm during early development.
In: The Journal of cell biology, 147 (1)
Artikel, Bibliographie

Derer, W ; Easwaran, H. P. ; Knopf, C. W. ; Leonhardt, H. ; Cardoso, M. Cristina (1999)
Direct protein transfer to terminally differentiated muscle cells.
In: Journal of molecular medicine, 77 (8)
Artikel, Bibliographie

Engel, F. B. ; Hauck, L. ; Cardoso, M. Cristina ; Leonhardt, H. ; Dietz, R. ; Harsdorf, R. von (1999)
A mammalian myocardial cell-free system to study cell cycle reentry in terminally differentiated cardiomyocytes.
In: Circulation research, 85 (3)
Artikel, Bibliographie

Krämer, J. ; Aguirre-Arteta, A. M. ; Thiel, C. ; Gross, C. M. ; Dietz, R. ; Cardoso, M. Cristina ; Leonhardt, H. (1999)
A novel isoform of the smooth muscle cell differentiation marker smoothelin.
In: Journal of molecular medicine, 77 (2)
Artikel, Bibliographie

Leonhardt, H. ; Rahn, H. P. ; Cardoso, M. Cristina (1999)
Functional links between nuclear structure, gene expression, DNA replication, and methylation.
In: Critical reviews in eukaryotic gene expression, 9 (3-4)
Artikel, Bibliographie

Lee-Kirsch, M. A. ; Gaudet, F. ; Cardoso, M. Cristina ; Lindpaintner, K. (1999)
Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing.
In: Circulation research, 84 (2)
Artikel, Bibliographie

Harsdorf, R. von ; Hauck, L. ; Mehrhof, F. ; Wegenka, U. ; Cardoso, M. Cristina ; Dietz, R. (1999)
E2F-1 overexpression in cardiomyocytes induces downregulation of p21CIP1 and p27KIP1 and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I.
In: Circulation research, 85 (2)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H.
Hrsg.: Stein, G. ; Baserga, R. ; Denhardt, D. ; Giordano, A. (1999)
Differentiation, development and programmed cell death.
In: The Molecular Basis of Cell Cycle and Growth Control
Buchkapitel, Bibliographie

1998

Leonhardt, H. ; Rahn, H. P. ; Cardoso, M. Cristina (1998)
Intranuclear targeting of DNA replication factors.
In: Journal of cellular biochemistry, 72 (S30-31)
Artikel, Bibliographie

Gaudet, F. ; Talbot, D. ; Leonhardt, H. ; Jaenisch, R. (1998)
A short DNA methyltransferase isoform restores methylation in vivo.
In: The Journal of biological chemistry, 273 (49)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. (1998)
Protein targeting to subnuclear higher order structures: a new level of regulation and coordination of nuclear processes.
In: Journal of cellular biochemistry, 70 (2)
Artikel, Bibliographie

1997

Cardoso, M. Cristina ; Joseph, C. ; Rahn, H. P. ; Reusch, R. ; Nadal-Ginard, B. ; Leonhardt, H. (1997)
Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo.
In: The Journal of cell biology, 139 (3)
Artikel, Bibliographie

1996

Tucker, K. L. ; Talbot, D. ; Lee-Kirsch, M. A. ; Leonhardt, H. ; Jaenisch, R. (1996)
Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene.
In: Proceedings of the National Academy of Sciences of the United States of America, 93 (23)
Artikel, Bibliographie

Leonhardt, H. ; Cardoso, M. Cristina (1996)
Targeting and association of proteins with functional domains in the nucleus: the insoluble solution.
In: International review of cytology, 162 (Part B)
doi: 10.1016/S0074-7696(08)62620-0
Artikel, Bibliographie

1995

Cardoso, M. Cristina ; Leonhardt, H.
Hrsg.: Pagano, M. (1995)
Immunofluorescence techniques in cell cycle studies.
In: Cell Cycle: Materials and Methods
Buchkapitel, Bibliographie

1993

Leonhardt, H. ; Bestor, T. H. (1993)
Structure, function and regulation of mammalian DNA methyltransferase.
In: EXS, 64
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. ; Nadal-Ginard, B. (1993)
Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication.
In: Cell, 74 (6)
Artikel, Bibliographie

McDermott, J. C. ; Cardoso, M. Cristina ; Yu, Y. T. ; Andres, V. ; Leifer, D. ; Krainc, D. ; Lipton, S. A. ; Nadal-Ginard, B. (1993)
hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.
In: Molecular and cellular biology, 13 (4)
Artikel, Bibliographie

1992

Leonhardt, H. ; Page, A. W. ; Weier, H. U. ; Bestor, T. H. (1992)
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei.
In: Cell, 71 (5)
Artikel, Bibliographie

1991

Czank, A. ; Häuselmann, R. ; Page, A. W. ; Leonhardt, H. ; Bestor, T. H. ; Schaffner, W. ; Hergersberg, M. (1991)
Expression in mammalian cells of a cloned gene encoding murine DNA methyltransferase.
In: Gene, 109 (2)
Artikel, Bibliographie