Milden-Appel, Manuela ; Paravicini, Markus ; Milden, Jannick P. ; Schüßler, Martin ; Jakoby, Rolf ; Cardoso, M. Cristina (2024)
Uptake of substances into living mammalian cells by microwave induced perturbation of the plasma membrane.
In: Scientific Reports, 14 (1)
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Arroyo, Maria ; Casas-Delucchi, Corella S. ; Pabba, Maruthi K. ; Prorok, Paulina ; Pradhan, Sunil K. ; Rausch, Cathia ; Lehmkuhl, Anne ; Maiser, Andreas ; Buschbeck, Marcus ; Pasque, Vincent ; Bernstein, Emily ; Luck, Katja ; Cardoso, M. Cristina (2024)
Histone variant macroH2A1 regulates synchronous firing of replication origins in the inactive X chromosome.
In: Nucleic acids research, 52 (9)
doi: 10.1093/nar/gkae734
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Ritter, C. ; Lee, J.-Y. ; Pham, M.-T. ; Pabba, M. K. ; Cardoso, M. Cristina ; Bartenschlager, R. ; Rohr, K. (2024)
Multi-detector fusion and Bayesian smoothing for tracking viral and chromatin structures.
In: Medical image analysis, 97
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Pabba, Maruthi K. ; Meyer, Janis ; Celikay, Kerem ; Schermelleh, Lothar ; Rohr, Karl ; Cardoso, M. Cristina (2024)
DNA choreography: correlating mobility and organization of DNA across different resolutions from loops to chromosomes.
In: Histochemistry and cell biology, 162 (2)
doi: 10.1007/s00418-024-02285-x
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Pradhan, Sunil Kumar ; Lozoya, Teresa ; Prorok, Paulina ; Yuan, Yue ; Lehmkuhl, Anne ; Zhang, Peng ; Cardoso, M. Cristina (2024)
Developmental changes in genome replication progression in pluripotent versus differentiated human cells.
In: Genes, 15 (3)
doi: 10.3390/genes15030305
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Schmidt, Annika ; Zhang, Hui ; Schmitt, Stephanie ; Rausch, Cathia ; Popp, Oliver ; Chen, Jiaxuan ; Cmarko, Dusan ; Butter, Falk ; Dittmar, Gunnar ; Lermyte, Frederik ; Cardoso, M. Cristina (2024)
The proteomic composition and organization of constitutive heterochromatin in mouse tissues.
In: Cells, 13 (2)
doi: 10.3390/cells13020139
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Prorok, Paulina ; Wolf, Eva ; Cardoso, M. Cristina (2024)
Timeless-Tipin interactions with MCM and RPA mediate DNA replication stress response.
In: Frontiers in cell and developmental biology, 12
doi: 10.3389/fcell.2024.1346534
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Zhang, Hui ; Qin, Weihua ; Romero, Hector ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2023)
Heterochromatin organization and phase separation.
In: Nucleus (Austin, Tex.), 14 (1)
doi: 10.1080/19491034.2022.2159142
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Pabba, Maruthi Kumar ; Ritter, Christian ; Chagin, Vadim O. ; Meyer, Janis ; Celikay, Kerem ; Stear, Jeffrey H. ; Loerke, Dinah ; Kolobynina, Ksenia ; Prorok, Paulina ; Schmid, Alice Kristin ; Leonhardt, Heinrich ; Rohr, Karl ; Cardoso, M. Cristina (2023)
Replisome loading reduces chromatin motion independent of DNA synthesis.
In: eLife, 12
doi: 10.7554/eLife.87572
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Amiri, Anahid ; Dietz, Christian ; Rapp, Alexander ; Cardoso, M. Cristina ; Stark, Robert W. (2023)
The cyto-linker and scaffolding protein "plectin" mis-localization leads to softening of cancer cells.
In: Nanoscale, 15 (36)
doi: 10.1039/d3nr02226a
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Arroyo, María ; Hastert, Florian D. ; Zhadan, Andreas ; Schelter, Florian ; Zimbelmann, Susanne ; Rausch, Cathia ; Ludwig, Anne K. ; Carell, Thomas ; Cardoso, M. Cristina (2023)
Author Correction: Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
In: Nature communications, 14 (1)
doi: 10.1038/s41467-023-36067-1
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Pradhan, Sunil Kumar ; Cardoso, M. Cristina (2023)
Analysis of Cell Cycle and DNA Compaction Dependent Subnuclear Distribution of Histone Marks.
In: HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Auflage: 2nd Edition
doi: 10.1007/978-1-0716-2788-4_15
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Zhang, Hui ; Romero, Hector ; Schmidt, Annika ; Gagova, Katalina ; Qin, Weihua ; Bertulat, Bianca ; Lehmkuhl, Anne ; Milden, Manuela ; Eck, Malte ; Meckel, Tobias ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2022)
MeCP2-induced heterochromatin organization is driven by oligomerization-based liquid–liquid phase separation and restricted by DNA methylation.
In: Nucleus (Austin, Tex.), 13 (1)
doi: 10.1080/19491034.2021.2024691
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Qin, Weihua ; Steinek, Clemens ; Kolobynina, Ksenia ; Forné, Ignasi ; Imhof, Axel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2022)
Probing protein ubiquitination in live cells.
In: Nucleic acids research, 50 (21)
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Arroyo, María ; Hastert, Florian D. ; Zhadan, Andreas ; Schelter, Florian ; Zimbelmann, Susanne ; Rausch, Cathia ; Ludwig, Anne K. ; Carell, Thomas ; Cardoso, M. Cristina (2022)
Isoform-specific and ubiquitination dependent recruitment of Tet1 to replicating heterochromatin modulates methylcytosine oxidation.
In: Nature communications, 13 (1)
doi: 10.1038/s41467-022-32799-8
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Schmidt, Annika ; Frei, Jana ; Poetsch, Ansgar ; Chittka, Alexandra ; Zhang, Hui ; Aßmann, Chris ; Lehmkuhl, Anne ; Bauer, Uta-Maria ; Nuber, Ulrike A. ; Cardoso, M. Cristina (2022)
MeCP2 heterochromatin organization is modulated by arginine methylation and serine phosphorylation.
In: Frontiers in cell and developmental biology, 10
doi: 10.3389/fcell.2022.941493
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Kolobynina, Ksenia G. ; Rapp, Alexander ; Cardoso, M. Cristina (2022)
Chromatin Ubiquitination Guides DNA Double Strand Break Signaling and Repair.
In: Frontiers in cell and developmental biology, 10
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Mamberti, Stefania ; Pabba, Maruthi K. ; Rapp, Alexander ; Cardoso, M. Cristina ; Scholz, Michael (2022)
The Chromatin Architectural Protein CTCF Is Critical for Cell Survival upon Irradiation-Induced DNA Damage.
In: International journal of molecular sciences, 23 (7)
doi: 10.3390/ijms23073896
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Rausch, Cathia ; Zhang, Peng ; Casas-Delucchi, Corella S. ; Daiß, Julia L. ; Engel, Christoph ; Coster, Gideon ; Hastert, Florian D. ; Weber, Patrick ; Cardoso, M. Cristina (2021)
Cytosine base modifications regulate DNA duplex stability and metabolism.
In: Nucleic acids research, 49 (22)
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Qin, Weihua ; Stengl, Andreas ; Ugur, Enes ; Leidescher, Susanne ; Ryan, Joel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
HP1β carries an acidic linker domain and requires H3K9me3 for phase separation.
In: Nucleus (Austin, Tex.), 12 (1)
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Duan, Ningjun ; Arroyo, Maria ; Deng, Wen ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
Visualization and characterization of RNA-protein interactions in living cells.
In: Nucleic acids research, 49 (18)
doi: 10.1093/nar/gkab614
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Qin, Weihua ; Ugur, Enes ; Mulholland, Christopher B. ; Bultmann, Sebastian ; Solovei, Irina ; Modic, Miha ; Smets, Martha ; Wierer, Michael ; Forné, Ignasi ; Imhof, Axel ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2021)
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency.
In: Nucleic acids research, 49 (13)
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Spilger, Roman ; Lee, Ji-Young ; Chagin, Vadim O. ; Schermelleh, Lothar ; Cardoso, M. Cristina ; Bartenschlager, Ralf ; Rohr, Karl (2021)
Deep probabilistic tracking of particles in fluorescence microscopy images.
In: Medical image analysis, 72
doi: 10.1016/j.media.2021.102128
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Gnan, Stefano ; Flyamer, Ilya M. ; Klein, Kyle N. ; Castelli, Eleonora ; Rapp, Alexander ; Maiser, Andreas ; Chen, Naiming ; Weber, Patrick ; Enervald, Elin ; Cardoso, M. Cristina ; Bickmore, Wendy A. ; Gilbert, David M. ; Buonomo, Sara C. B. (2021)
Nuclear organisation and replication timing are coupled through RIF1-PP1 interaction.
In: Nature communications, 12 (1)
doi: 10.1038/s41467-021-22899-2
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Levone, Brunno R. ; Lenzken, Silvia C. ; Antonaci, Marco ; Maiser, Andreas ; Rapp, Alexander ; Conte, Francesca ; Reber, Stefan ; Mechtersheimer, Jonas ; Ronchi, Antonella E. ; Mühlemann, Oliver ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Ruepp, Marc-David ; Barabino, Silvia M. L. (2021)
FUS-dependent liquid-liquid phase separation is important for DNA repair initiation.
In: The Journal of cell biology, 220 (5)
doi: 10.1083/jcb.202008030
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Schneider, Anselm F. L. ; Kithil, Marina ; Cardoso, M. Cristina ; Lehmann, Martin ; Hackenberger, Christian P. R. (2021)
Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives.
In: Nature chemistry, 13 (6)
doi: 10.1038/s41557-021-00661-x
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Rausch, Cathia ; Weber, Patrick ; Prorok, Paulina ; Hörl, David ; Maiser, Andreas ; Lehmkuhl, Anne ; Chagin, Vadim O. ; Casas-Delucchi, Corella S. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2020)
Developmental differences in genome replication program and origin activation.
In: Nucleic acids research, 48 (22)
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Cremer, Marion ; Brandstetter, Katharina ; Maiser, Andreas ; Rao, Suhas S. P. ; Schmid, Volker J. ; Guirao-Ortiz, Miguel ; Mitra, Namita ; Mamberti, Stefania ; Klein, Kyle N. ; Gilbert, David M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Lieberman Aiden, Erez ; Harz, Hartmann ; Cremer, Thomas (2020)
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
In: Nature Communications, 11 (1)
doi: 10.1038/s41467-020-19876-6
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Cremer, Marion ; Brandstetter, Katharina ; Maiser, Andreas ; Rao, Suhas S. P. ; Schmid, Volker J. ; Guirao-Ortiz, Miguel ; Mitra, Namita ; Mamberti, Stefania ; Klein, Kyle N. ; Gilbert, David M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Aiden, Erez Lieberman ; Harz, Hartmann ; Cremer, Thomas (2020)
Cohesin depleted cells rebuild functional nuclear compartments after endomitosis.
In: Nature communications, 11 (1)
doi: 10.1038/s41467-020-19876-6
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Mamberti, Stefania ; Cardoso, M. Cristina (2020)
Are the processes of DNA replication and DNA repair reading a common structural chromatin unit?
In: Nucleus (Austin, Tex.), 11 (1)
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Schwach, Jonathan ; Kolobynina, Ksenia ; Brandstetter, Katharina ; Gerlach, Marcus ; Ochtrop, Philipp ; Helma, Jonas ; Hackenberger, Christian P. R. ; Harz, Hartmann ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Stengl, Andreas (2020)
Site-Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy.
In: Chembiochem : a European journal of chemical biology
doi: 10.1002/cbic.202000727
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Weichmann, Franziska ; Hett, Robert ; Schepers, Aloys ; Ito-Kureha, Taku ; Flatley, Andrew ; Slama, Kaouthar ; Hastert, Florian D. ; Angstman, Nicholas B. ; Cardoso, M. Cristina ; König, Julian ; Hüttelmaier, Stefan ; Dieterich, Christoph ; Canzar, Stefan ; Helm, Mark ; Heissmeyer, Vigo ; Feederle, Regina ; Meister, Gunter (2020)
Validation strategies for antibodies targeting modified ribonucleotides.
In: RNA, 26 (10)
doi: 10.1261/rna.076026.120
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Rausch, Cathia ; Hastert, Florian D. ; Cardoso, M. Cristina (2020)
DNA modification readers and writers and their interplay.
In: Journal of molecular biology, 432 (6)
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Schneider, Markus ; Trummer, Carina ; Stengl, Andreas ; Zhang, Peng ; Szwagierczak, Aleksandra ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Bauer, Christina ; Antes, Iris (2020)
Systematic analysis of the binding behaviour of UHRF1 towards different methyl- and carboxylcytosine modification patterns at CpG dyads.
In: PloS one, 15 (2)
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Napolitano, Giuliana ; Tagliaferri, Daniela ; Fusco, Salvatore ; Cirillo, Carmine ; De Martino, Ilaria ; Addeo, Martina ; Mazzone, Pellegrino ; Russo, Nicola Antonino ; Natale, Francesco ; Cardoso, M. Cristina ; De Luca, Luciana ; Lamorte, Daniela ; La Rocca, Francesco ; De Felice, Mario ; Falco, Geppino (2020)
A novel member of Prame family, Gm12794c, counteracts retinoic acid differentiation through the methyltransferase activity of PRC2.
In: Cell death and differentiation, 27 (1)
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Schmidt, Annika ; Zhang, Hui ; Cardoso, M. Cristina (2020)
MeCP2 and Chromatin Compartmentalization.
In: Cells, 9 (4)
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Chagin, Vadim O. ; Reinhart, Britta ; Becker, Annette ; Mortusewicz, Oliver ; Jost, K. Laurence ; Rapp, Alexander ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2019)
Processive DNA synthesis is associated with localized decompaction of constitutive heterochromatin at the sites of DNA replication and repair.
In: Nucleus (Austin, Tex.), 10 (1)
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Heinz, Kathrin S. ; Cardoso, M. Cristina (2019)
Targeted Manipulation/Repositioning of Subcellular Structures and Molecules.
In: Methods in molecular biology (Clifton, N.J.), 2038
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Kasper, Marc-André ; Glanz, Maria ; Stengl, Andreas ; Penkert, Martin ; Klenk, Simon ; Sauer, Tom ; Schumacher, Dominik ; Helma, Jonas ; Krause, Eberhard ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Hackenberger, Christian P. R. (2019)
Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations.
In: Angewandte Chemie International Edition, 58 (34)
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Zhang, Yi ; Bertulat, Bianca ; Tencer, Adam H. ; Ren, Xiaojun ; Wright, Gregory M. ; Black, Joshua ; Cardoso, M. Cristina ; Kutateladze, Tatiana G. (2019)
MORC3 Forms Nuclear Condensates through Phase Separation.
In: iScience, 17
doi: 10.1016/j.isci.2019.06.030
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Schmidt, Sönke ; Schubler, Martin ; Hessinger, Carolin ; Schuster, Christian ; Bertulat, Bianca ; Kithil, Marina ; Cardoso, M. Cristina ; Jakoby, Rolf (2019)
Microwave Induced Electroporation of Adherent Mammalian Cells at 18 GHz.
In: IEEE Access, 7
doi: 10.1109/ACCESS.2019.2923073
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Zhang, Yi ; Klein, Brianna J. ; Cox, Khan L. ; Bertulat, Bianca ; Tencer, Adam H. ; Holden, Michael R. ; Wright, Gregory M. ; Black, Joshua ; Cardoso, M. Cristina ; Poirier, Michael G. ; Kutateladze, Tatiana G. (2019)
Mechanism for autoinhibition and activation of the MORC3 ATPase.
In: Proceedings of the National Academy of Sciences of the United States of America, 116 (13)
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Heinz, Kathrin S. ; Rapp, Alexander ; Casas-Delucchi, Corella S. ; Lehmkuhl, Anne ; Romero-Fernández, Ismael ; Sánchez, Antonio ; Krämer, Oliver H. ; Marchal, J. Alberto ; Cardoso, M. Cristina (2019)
DNA replication dynamics of vole genome and its epigenetic regulation.
In: Epigenetics & chromatin, 12 (1)
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Weber, Patrick ; Rausch, Cathia ; Scholl, Annina ; Cardoso, M. Cristina (2019)
Repli-FISH (Fluorescence in Situ Hybridization): Application of 3D-(Immuno)-FISH for the Study of DNA Replication Timing of Genetic Repeat Elements.
In: OBM Genetics, 3 (1)
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Natale, Francesco ; Scholl, Annina ; Rapp, Alexander ; Yu, Wei ; Rausch, Cathia ; Cardoso, M. Cristina (2018)
DNA replication and repair kinetics of Alu, LINE-1 and satellite III genomic repetitive elements.
In: Epigenetics & chromatin, 11 (1)
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Heinz, Kathrin S. ; Casas-Delucchi, Corella S. ; Török, Timea ; Cmarko, Dusan ; Rapp, Alexander ; Raska, Ivan ; Cardoso, M. Cristina (2018)
Peripheral re-localization of constitutive heterochromatin advances its replication timing and impairs maintenance of silencing marks.
In: Nucleic acids research, 46 (12)
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Kind, Barbara ; Wolf, Christine ; Engel, Kerstin ; Rapp, Alexander ; Cardoso, M. Cristina ; Lee-Kirsch, Min Ae (2018)
Single Cell Gel Electrophoresis for the Detection of Genomic Ribonucleotides.
In: Methods in molecular biology (Clifton, N.J.), 1672
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Herce, Henry D. ; Schumacher, Dominik ; Schneider, Anselm F. L. ; Ludwig, Anne K. ; Mann, Florian A. ; Fillies, Marion ; Kasper, Marc-André ; Reinke, Stefan ; Krause, Eberhard ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. (2017)
Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.
In: Nature chemistry, 9 (8)
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Zhang, Peng ; Rausch, Cathia ; Hastert, Florian D. ; Boneva, Boyana ; Filatova, Alina ; Patil, Sujit J. ; Nuber, Ulrike A. ; Gao, Yu ; Zhao, Xinyu ; Cardoso, M. Cristina (2017)
Methyl-CpG binding domain protein 1 regulates localization and activity of Tet1 in a CXXC3 domain-dependent manner.
In: Nucleic acids research, 45 (12)
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Natale, Francesco ; Rapp, Alexander ; Yu, Wei ; Maiser, Andreas ; Harz, Hartmann ; Scholl, Annina ; Grulich, Stephan ; Anton, Tobias ; Hörl, David ; Chen, Wei ; Durante, Marco ; Taucher-Scholz, Gisela ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
Identification of the elementary structural units of the DNA damage response.
In: Nature communications, 8
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Erbeldinger, Nadine ; Rapp, Felicitas ; Ktitareva, Svetlana ; Wendel, Philipp ; Bothe, Anna S. ; Dettmering, Till ; Durante, Marco ; Friedrich, Thomas ; Bertulat, Bianca ; Meyer, Stephanie ; Cardoso, M. Cristina ; Hehlgans, Stephanie ; Rödel, Franz ; Fournier, Claudia (2017)
Measuring Leukocyte Adhesion to (Primary) Endothelial Cells after Photon and Charged Particle Exposure with a Dedicated Laminar Flow Chamber.
In: Frontiers in immunology, 8
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Zhang, Peng ; Ludwig, Anne K. ; Hastert, Florian D. ; Rausch, Cathia ; Lehmkuhl, Anne ; Hellmann, Ines ; Smets, Martha ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
L1 retrotransposition is activated by Ten-eleven-translocation protein 1 and repressed by methyl-CpG binding proteins.
In: Nucleus (Austin, Tex.), 8 (5)
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Muster, Britta ; Rapp, Alexander ; Cardoso, M. Cristina (2017)
Systematic analysis of DNA damage induction and DNA repair pathway activation by continuous wave visible light laser micro-irradiation.
In: AIMS Genetics, 4 (1)
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Zhang, Peng ; Hastert, Florian D. ; Ludwig, Anne K. ; Breitwieser, Kai ; Hofstätter, Maria ; Cardoso, M. Cristina (2017)
DNA base flipping analytical pipeline, Biology Methods and Protocols.
In: Biology Methods and Protocols, 2 (1)
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Ludwig, Anne K. ; Zhang, Peng ; Hastert, Florian D. ; Meyer, Stephanie ; Rausch, Cathia ; Herce, Henry D. ; Müller, Udo ; Lehmkuhl, Anne ; Hellmann, Ines ; Trummer, Carina ; Storm, Christian ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2017)
Binding of MBD proteins to DNA blocks Tet1 function thereby modulating transcriptional noise.
In: Nucleic acids research, 45 (5)
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Reinhart, Marius ; Cardoso, M. Cristina (2017)
A journey through the microscopic ages of DNA replication.
In: Protoplasma, 254 (3)
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Löb, D. ; Lengert, N. ; Chagin, V. O. ; Reinhart, M. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina ; Drossel, B. (2016)
3D replicon distributions arise from stochastic initiation and domino-like DNA replication progression.
In: Nature communications, 7
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Chagin, V. O. ; Casas-Delucchi, C. S. ; Reinhart, M. ; Schermelleh, L. ; Markaki, Y. ; Maiser, A. ; Bolius, J. J. ; Bensimon, A. ; Fillies, M. ; Domaing, P. ; Rozanov, Y. M. ; Leonhardt, H. ; Cardoso, M. Cristina (2016)
4D Visualization of replication foci in mammalian cells corresponding to individual replicons.
In: Nature communications, 7
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Ludwig, Anne K. ; Zhang, Peng ; Cardoso, M. Cristina (2016)
Modifiers and Readers of DNA Modifications and Their Impact on Genome Structure, Expression, and Stability in Disease.
In: Frontiers in genetics, 7
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Becker, Annette ; Zhang, Peng ; Allmann, Lena ; Meilinger, Daniela ; Bertulat, Bianca ; Eck, Daniel ; Hofstaetter, Maria ; Bartolomei, Giody ; Hottiger, Michael ; Schreiber, Valerie ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2016)
Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.
In: The Journal of biological chemistry, 291 (10)
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Wolf, Christine ; Rapp, Alexander ; Berndt, Nicole ; Staroske, Wolfgang ; Schuster, Max ; Dobrick-Mattheuer, Manuela ; Kretschmer, Stefanie ; König, Nadja ; Kurth, Thomas ; Wieczorek, Dagmar ; Kast, Karin ; Cardoso, M. Cristina ; Günther, Claudia ; Lee-Kirsch, Min Ae (2016)
RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA.
In: Nature communications, 7
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Martin, Robert M. ; Herce, Henry D. ; Ludwig, Anne K. ; Cardoso, M. Cristina (2016)
Visualization of the Nucleolus in Living Cells with Cell-Penetrating Fluorescent Peptides.
In: Methods in molecular biology (Clifton, N.J.), 1455
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Gracheva, Ekaterina ; Chitale, Shalaka ; Wilhelm, Thomas ; Rapp, Alexander ; Byrne, Jonathan ; Stadler, Jens ; Medina, Rebeca ; Cardoso, M. Cristina ; Richly, Holger (2016)
ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair.
In: The Journal of cell biology, 213 (2)
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Lengert, Laurin ; Lengert, Nicor ; Drossel, Barbara ; Cardoso, M. Cristina ; Muster, Britta ; Nowak, Danny ; Rapp, Alexander (2015)
Discrimination of Kinetic Models by a Combination of Microirradiation and Fluorescence Photobleaching.
In: Biophysical journal, 109 (8)
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Nischan, Nicole ; Herce, Henry D. ; Natale, Francesco ; Bohlke, Nina ; Budisa, Nediljko ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. (2015)
Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability.
In: Angewandte Chemie (International ed. in English), 54 (6)
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Romero-Fernández, I. ; Casas-Delucchi, C. S. ; Cano-Linares, M. ; Arroyo, M. ; Sánchez, A. ; Cardoso, M. Cristina ; Marchal, J. A. (2015)
Epigenetic modifications in sex heterochromatin of vole rodents.
In: Chromosoma, 124 (3)
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Jost, K. Laurence ; Bertulat, Bianca ; Rapp, Alexander ; Brero, Alessandro ; Hardt, Tanja ; Domaing, Petra ; Gösele, Claudia ; Schulz, Herbert ; Hübner, Norbert ; Cardoso, M. Cristina (2015)
Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood.
In: Epigenetics & chromatin, 8
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Rajan, Malini ; Mortusewicz, Oliver ; Rothbauer, Ulrich ; Hastert, Florian D. ; Schmidthals, Katrin ; Rapp, Alexander ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2015)
Generation of an alpaca-derived nanobody recognizing γ-H2AX.
In: FEBS open bio, 5
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Helma, Jonas ; Cardoso, M. Cristina ; Muyldermans, Serge ; Leonhardt, Heinrich (2015)
Nanobodies and recombinant binders in cell biology.
In: The Journal of cell biology, 209 (5)
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Martin, Robert M. ; Ter-Avetisyan, Gohar ; Herce, Henry D. ; Ludwig, Anne K. ; Lättig-Tünnemann, Gisela ; Cardoso, M. Cristina (2015)
Principles of protein targeting to the nucleolus.
In: Nucleus (Austin, Tex.), 6 (4)
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Kretschmer, Stefanie ; Wolf, Christine ; König, Nadja ; Staroske, Wolfgang ; Guck, Jochen ; Häusler, Martin ; Luksch, Hella ; Nguyen, Laura A. ; Kim, Baek ; Alexopoulou, Dimitra ; Dahl, Andreas ; Rapp, Alexander ; Cardoso, M. Cristina ; Shevchenko, Anna ; Lee-Kirsch, Min Ae (2015)
SAMHD1 prevents autoimmunity by maintaining genome stability.
In: Annals of the rheumatic diseases, 74 (3)
Artikel, Bibliographie

Schumacher, Dominik ; Helma, Jonas ; Mann, Florian A. ; Pichler, Garwin ; Natale, Francesco ; Krause, Eberhard ; Cardoso, M. Cristina ; Hackenberger, Christian P. R. ; Leonhardt, Heinrich (2015)
Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.
In: Angewandte Chemie (International ed. in English), 54 (46)
Artikel, Bibliographie

Kind, Barbara ; Muster, Britta ; Staroske, Wolfgang ; Herce, Henry D. ; Sachse, René ; Rapp, Alexander ; Schmidt, Franziska ; Koss, Sarah ; Cardoso, M. Cristina ; Lee-Kirsch, Min Ae (2014)
Altered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutières syndrome.
In: Human molecular genetics, 23 (22)
Artikel, Bibliographie

Cazzalini, Ornella ; Sommatis, Sabrina ; Tillhon, Micol ; Dutto, Ilaria ; Bachi, Angela ; Rapp, Alexander ; Nardo, Tiziana ; Scovassi, A. Ivana ; Necchi, Daniela ; Cardoso, M. Cristina ; Stivala, Lucia A. ; Prosperi, Ennio (2014)
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.
In: Nucleic acids research, 42 (13)
Artikel, Bibliographie

Dornblut, Carsten ; Quinn, Nadine ; Monajambashi, Shamci ; Prendergast, Lisa ; van Vuuren, Chelly ; Münch, Sandra ; Deng, Wen ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Hoischen, Christian ; Diekmann, Stephan ; Sullivan, Kevin F. (2014)
A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.
In: Open biology, 4
Artikel, Bibliographie

Song, Congdi ; Feodorova, Yana ; Guy, Jacky ; Peichl, Leo ; Jost, Katharina Laurence ; Kimura, Hiroshi ; Cardoso, M. Cristina ; Bird, Adrian ; Leonhardt, Heinrich ; Joffe, Boris ; Solovei, Irina (2014)
DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution.
In: Epigenetics & chromatin, 7
Artikel, Bibliographie

Herce, Henry D. ; Garcia, Angel E. ; Cardoso, M. Cristina (2014)
Fundamental molecular mechanism for the cellular uptake of guanidinium-rich molecules.
In: Journal of the American Chemical Society, 136 (50)
Artikel, Bibliographie

Wieneke, Ralph ; Laboria, Noemi ; Rajan, Malini ; Kollmannsperger, Alina ; Natale, Francesco ; Cardoso, M. Cristina ; Tampé, Robert (2014)
Live-cell targeting of His-tagged proteins by multivalent N-nitrilotriacetic acid carrier complexes.
In: Journal of the American Chemical Society, 136 (40)
Artikel, Bibliographie

Smirnov, E. ; Borkovec, J. ; Kováčik, L. ; Svidenská, S. ; Schröfel, A. ; Skalníková, M. ; Švindrych, Z. ; Křížek, P. ; Ovesný, M. ; Hagen, G. M. ; Juda, P. ; Michalová, K. ; Cardoso, M. Cristina ; Cmarko, D. ; Raška, I. (2014)
Separation of replication and transcription domains in nucleoli.
In: Journal of structural biology, 188 (3)
Artikel, Bibliographie

Sansoni, Viola ; Casas-Delucchi, Corella S. ; Rajan, Malini ; Schmidt, Andreas ; Bönisch, Clemens ; Thomae, Andreas W. ; Staege, Martin S. ; Hake, Sandra B. ; Cardoso, M. Cristina ; Imhof, Axel (2014)
The histone variant H2A.Bbd is enriched at sites of DNA synthesis.
In: Nucleic acids research, 42 (10)
Artikel, Bibliographie

Herce, Henry D. ; Rajan, Malini ; Lättig-Tünnemann, Gisela ; Fillies, Marion ; Cardoso, M. Cristina (2014)
A novel cell permeable DNA replication and repair marker.
In: Nucleus (Austin, Tex.), 5 (6)
Artikel, Bibliographie

Hörner, Sebastian ; Fabritz, Sebastian ; Herce, Henry D. ; Avrutina, Olga ; Dietz, Christian ; Stark, Robert W. ; Cardoso, M. Cristina ; Kolmar, Harald (2013)
Cube-octameric silsesquioxane-mediated cargo peptide delivery into living cancer cells.
In: Organic & biomolecular chemistry, 11 (14)
Artikel, Bibliographie

Becker, Annette ; Allmann, Lena ; Hofstätter, Maria ; Casà, Valentina ; Weber, Patrick ; Lehmkuhl, Anne ; Herce, Henry D. ; Cardoso, M. Cristina (2013)
Direct Homo- and Hetero-Interactions of MeCP2 and MBD2.
In: PloS one, 8 (1)
Artikel, Bibliographie

Herce, H. D. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina (2013)
New image colocalization coefficient for fluorescence microscopy to quantify (bio-)molecular interactions.
In: Journal of microscopy, 249 (3)
Artikel, Bibliographie

Reinhart, Marius ; Casas-Delucchi, Corella S. ; Cardoso, M. Cristina (2013)
Spatiotemporal visualization of DNA replication dynamics.
In: Methods in molecular biology (Clifton, N.J.), 1042
Artikel, Bibliographie

Herce, Henry D. ; Deng, Wen ; Helma, Jonas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2013)
Visualization and targeted disruption of protein interactions in living cells.
In: Nature communications, 4
Artikel, Bibliographie

Brink, Maartje C. ; Piebes, Diewertje G. E. ; Groote, Marloes L. de ; Luijsterburg, Martijn S. ; Casas-Delucchi, Corella S. ; Driel, Roeland van ; Rots, Marianne G. ; Cardoso, M. Cristina ; Verschure, Pernette J. (2013)
A role for MeCP2 in switching gene activity via chromatin unfolding and HP1γ displacement.
In: PloS on, 8 (7)
Artikel, Bibliographie

Jost, K. Laurence ; Bertulat, Bianca ; Cardoso, M. Cristina (2012)
Heterochromatin and gene positioning: inside, outside, any side?
In: Chromosoma, 121 (6)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Bemmel, Joke G. van ; Haase, Sebastian ; Herce, Henry D. ; Nowak, Danny ; Meilinger, Daniela ; Stear, Jeffrey H. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2012)
Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin.
In: Nucleic acids research, 40 (1)
Artikel, Bibliographie

Bertulat, Bianca ; De Bonis, Maria Luigia ; Della Ragione, Floriana ; Lehmkuhl, Anne ; Milden, Manuela ; Storm, Christian ; Jost, K. Laurence ; Scala, Simona ; Hendrich, Brian ; D'Esposito, Maurizio ; Cardoso, M. Cristina (2012)
MeCP2 Dependent Heterochromatin Reorganization during Neural Differentiation of a Novel Mecp2-Deficient Embryonic Stem Cell Reporter Line.
In: PloS one, 7 (10)
Artikel, Bibliographie

Vasiliou, Sylvia A. ; Ali, Fahad R. ; Haddley, Kate ; Cardoso, M. Cristina ; Bubb, Vivien J. ; Quinn, John P. (2012)
The SLC6A4 VNTR genotype determines transcription factor binding and epigenetic variation of this gene in response to cocaine in vitro.
In: Addiction biology, 17 (1)
Artikel, Bibliographie

Eskat, Anja ; Deng, Wen ; Hofmeister, Antje ; Rudolphi, Sven ; Emmerth, Stephan ; Hellwig, Daniela ; Ulbricht, Tobias ; Döring, Volker ; Bancroft, James M. ; McAinsh, Andrew D. ; Cardoso, M. Cristina ; Meraldi, Patrick ; Hoischen, Christian ; Leonhardt, Heinrich ; Diekmann, Stephan (2012)
Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.
In: PloS one, 7 (9)
Artikel, Bibliographie

Cardoso, M. Cristina ; Schneider, Katrin ; Martin, Robert M. ; Leonhardt, Heinrich (2012)
Structure, function and dynamics of nuclear subcompartments.
In: Current opinion in cell biology, 24 (1)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Becker, Annette ; Bolius, Janine J. ; Cardoso, M. Cristina (2012)
Targeted manipulation of heterochromatin rescues MeCP2 Rett mutants and re-establishes higher order chromatin organization.
In: Nucleic acids research, 40 (22)
Artikel, Bibliographie

Greinert, R. ; Volkmer, B. ; Henning, S. ; Breitbart, E. W. ; Greulich, K. O. ; Cardoso, M. Cristina ; Rapp, Alexander (2012)
UVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.
In: Nucleic acids research, 40 (20)
Artikel, Bibliographie

Stear, Jeffrey H. ; Loerke, Dinah ; Chagin, Vadim ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
DNA replication machinery clamps down on chromatin mobility.
In: European biophysics journal with biophysics letters, 40
Artikel, Bibliographie

Lättig-Tünnemann, G. ; Prinz, M. ; Hoffmann, D. ; Behlke, J. ; Palm-Apergi, C. ; Herce, H. D. ; Cardoso, M. Cristina (2011)
Backbone rigidity and static presentation of guanidinium groups increases cellular uptake of arginine-rich cell-penetrating peptides.
In: Nature communications, 2
doi: 10.1038/ncomms1459
Artikel, Bibliographie

Jost, K. Laurence ; Haase, Sebastian ; Smeets, Daniel ; Schrode, Nadine ; Schmiedel, Jörn M. ; Bertulat, Bianca ; Herzel, Hanspeter ; Cremer, Marion ; Cardoso, M. Cristina (2011)
3D-Image analysis platform monitoring relocation of pluripotency genes during reprogramming.
In: Nucleic acids research, 39 (17)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Cardoso, M. Cristina (2011)
Epigenetic control of DNA replication dynamics in mammals.
In: Nucleus (Austin, Tex.), 2 (5)
Artikel, Bibliographie

Jost, K. Laurence ; Rottach, Andrea ; Milden, Manuela ; Bertulat, Bianca ; Becker, Annette ; Wolf, Patricia ; Sandoval, Juan ; Petazzi, Paolo ; Huertas, Dori ; Esteller, Manel ; Kremmer, Elisabeth ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
Generation and Characterization of Rat and Mouse Monoclonal Antibodies Specific for MeCP2 and Their Use in X-Inactivation Studies.
In: PloS one, 6 (11)
Artikel, Bibliographie

Casas-Delucchi, Corella S. ; Brero, Alessandro ; Rahn, Hans-Peter ; Solovei, Irina ; Wutz, Anton ; Cremer, Thomas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2011)
Histone acetylation controls the inactive X chromosome replication dynamics.
In: Nature communications, 2
Artikel, Bibliographie

Agarwal, N. ; Becker, A. ; Jost, K. L. ; Haase, S. ; Thakur, B. K. ; Brero, A. ; Hardt, T. ; Kudo, S. ; Leonhart, H. ; Cardoso, M. Cristina (2011)
MeCP2 Rett mutations affect large scale chromatin organization.
In: Human molecular genetics, 20 (21)
doi: 10.1093/hmg/ddr346.
Artikel, Bibliographie

Frauer, C. ; Hoffmann, T. ; Bultmann, S. ; Casa, V. ; Cardoso, M. Cristina ; Antes, I. ; Leonhart, H. (2011)
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain.
In: PLoS One, 6
doi: 10.1371/journal.pone.0021306
Artikel, Bibliographie

Masata, M. ; Juda, P. ; Raska, O. ; Cardoso, M. Cristina ; Rask, I. (2011)
A fraction of MCM 2 proteins remain associated with replication foci during a major part of S phase.
In: Folia Biol (Praha), 57
Artikel, Bibliographie

Martin, Robert M. ; Cardoso, M. Cristina (2010)
Chromatin condensation modulates access and binding of nuclear proteins.
In: The FASEB journal, 24 (4)
doi: 10.1096/fj.08-128959
Artikel, Bibliographie

Baddeley, D. ; Chagin, V. O. ; Schermelleh, L. ; Martin, S. ; Pombo, A. ; Carlton, P. M. ; Gahl, A. ; Domaing, P. ; Birk, U. ; Leonhardt, H. ; Cremer, C. ; Cardoso, M. Cristina (2010)
Measurement of replication structures at the nanometer scale using super-resolution light microscopy.
In: Nucleic acids research, 38 (2)
doi: 10.1093/nar/gkp901
Artikel, Bibliographie

Kirchhofer, A. ; Helma, J. ; Schmidthals, K. ; Frauer, C. ; Cui, S. ; Karcher, A. ; Pellis, M. ; Muyldermans, S. ; Casas-Delucchi, C. S. ; Cardoso, M. Cristina ; Leonhardt, H. ; Hopfner, K. P. ; Rothbauer, U. (2010)
Modulation of protein properties in living cells using nanobodies.
In: Nature structural & molecular biology, 17 (1)
doi: 10.1038/nsmb.1727
Artikel, Bibliographie

Chagin, V. O. ; Stear, J. H. ; Cardoso, M. Cristina (2010)
Organization of DNA Replication.
In: Cold Spring Harb Perspect Biol., 2
doi: 10.1101/cshperspect.a000737
Artikel, Bibliographie

Zhu, Y. ; Wu, Z. ; Cardoso, M. Cristina ; Parris, D. S. (2010)
Processing of Lagging-Strand Intermediates In Vitro by Herpes Simplex Virus Type 1 DNA Polymerase.
In: Journal of Virology, 84 (15)
doi: 10.1128/JVI.01875-09
Artikel, Bibliographie

Ter-Avetisyan, Gohar ; Tünnemann, Gisela ; Nowak, Danny ; Nitschke, Matthias ; Herrmann, Andreas ; Drab, Marek ; Cardoso, M. Cristina (2009)
Cell entry of arginine-rich peptides is independent of endocytosis.
In: The Journal of biological chemistry, 284 (6)
Artikel, Bibliographie

Tünnemann, G. ; Cardoso, M. Cristina (2009)
Cell-Penetrating Peptides Uptake, Toxicity, and Applications.
In: Membrane-Active Peptides: methods and results on structure and function.- Ed. M. Castanho
Buchkapitel, Bibliographie

Ciobanasu, Corina ; Harms, Enno ; Tünnemann, Gisela ; Cardoso, M. Cristina ; Kubitscheck, Ulrich (2009)
Cell-penetrating HIV1 TAT peptides float on model lipid bilayers.
In: Biochemistry, 48 (22)
Artikel, Bibliographie

Liska, Frantisek ; Gosele, Claudia ; Rivkin, Eugene ; Tres, Laura ; Cardoso, M. Cristina ; Domaing, Petra ; Krejcí, Eliska ; Snajdr, Pavel ; Lee-Kirsch, Min Ae ; Rooij, Dirk G. de ; Kren, Vladimír ; Krenová, Drahomíra ; Kierszenbaum, Abraham L. ; Hubner, Norbert (2009)
Rat hd mutation reveals an essential role of centrobin in spermatid head shaping and assembly of the head-tail coupling apparatus.
In: Biology of reproduction, 81 (6)
Artikel, Bibliographie

Ersoy, Ilker ; Bunyak, Filiz ; Chagin, Vadim ; Cardoso, M. Cristina ; Palaniappan, Kannappan (2009)
Segmentation and Classification of Cell Cycle Phases in Fluorescence Imaging.
In: Lecture notes in computer science, 5762
Artikel, Bibliographie

Gupta, Shashank ; Höpner, Sabine ; Rupp, Bernd ; Günther, Sebastian ; Dickhaut, Katharina ; Agarwal, Noopur ; Cardoso, M. Cristina ; Kühne, Ronald ; Wiesmüller, Karl-Heinz ; Jung, Günther ; Falk, Kirsten ; Rötzschke, Olaf (2008)
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules.
In: PloS one, 3 (3)
Artikel, Bibliographie

Nitschke, Matthias ; Korte, Thomas ; Tielesch, Claudia ; Ter-Avetisyan, Gohar ; Tünnemann, Gisela ; Cardoso, M. Cristina ; Veit, Michael ; Herrmann, Andreas (2008)
Equine arteritis virus is delivered to an acidic compartment of host cells via clathrin-dependent endocytosis.
In: Virology, 377 (2)
Artikel, Bibliographie

Rottach, Andrea ; Kremmer, Elisabeth ; Nowak, Danny ; Boisguerin, Prisca ; Volkmer, Rudolf ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Rothbauer, Ulrich (2008)
Generation and characterization of a rat monoclonal antibody specific for PCNA.
In: Hybridoma, 27 (2)
Artikel, Bibliographie

Rottach, Andrea ; Kremmer, Elisabeth ; Nowak, Danny ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins.
In: Hybridoma, 27 (5)
Artikel, Bibliographie

Tünnemann, Gisela ; Ter-Avetisyan, Gohar ; Martin, Robert M. ; Stöckl, Martin ; Herrmann, Andreas ; Cardoso, M. Cristina (2008)
Live-cell analysis of cell penetration ability and toxicity of oligo-arginines.
In: Journal of peptide science : an official publication of the European Peptide Society, 14 (4)
Artikel, Bibliographie

Grünwald, David ; Martin, Robert M. ; Buschmann, Volker ; Bazett-Jones, David P. ; Leonhardt, Heinrich ; Kubitscheck, Ulrich ; Cardoso, M. Cristina (2008)
Probing intranuclear environments at the single-molecule level.
In: Biophysical journal, 94 (7)
Artikel, Bibliographie

Mortusewicz, Oliver ; Roth, Wera ; Li, Na ; Cardoso, M. Cristina ; Meisterernst, Michael ; Leonhardt, Heinrich (2008)
Recruitment of RNA polymerase II cofactor PC4 to DNA damage sites.
In: The Journal of cell biology, 183 (5)
Artikel, Bibliographie

Mortusewicz, Oliver ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Spatiotemporal dynamics of regulatory protein recruitment at DNA damage sites.
In: Journal of cellular biochemistry, 104 (5)
Artikel, Bibliographie

Schermelleh, Lothar ; Carlton, Peter M. ; Haase, Sebastian ; Shao, Lin ; Winoto, Lukman ; Kner, Peter ; Burke, Brian ; Cardoso, M. Cristina ; Agard, David A. ; Gustafsson, Mats G. L. ; Leonhardt, Heinrich ; Sedat, John W. (2008)
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy.
In: Science, 320 (5881)
Artikel, Bibliographie

Görisch, Sabine M. ; Sporbert, Anje ; Stear, Jeffrey H. ; Grunewald, Ingrid ; Nowak, Danny ; Warbrick, Emma ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2008)
Uncoupling the replication machinery: replication fork progression in the absence of processive DNA synthesis.
In: Cell cycle (Georgetown, Tex.), 7 (13)
Artikel, Bibliographie

Zolghadr, Kourosh ; Mortusewicz, Oliver ; Rothbauer, Ulrich ; Kleinhans, Regina ; Goehler, Heike ; Wanker, Erich E. ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2008)
A fluorescent two-hybrid assay for direct visualization of protein interactions in living cells.
In: Molecular & cellular proteomics : MCP, 7 (11)
Artikel, Bibliographie

Shumaker, Dale K. ; Solimando, Liliana ; Sengupta, Kaushik ; Shimi, Takeshi ; Adam, Stephen A. ; Grunwald, Antje ; Strelkov, Sergei V. ; Aebi, Ueli ; Cardoso, M. Cristina ; Goldman, Robert D. (2008)
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication.
In: The Journal of cell biology, 181 (2)
Artikel, Bibliographie

Rothbauer, Ulrich ; Zolghadr, Kourosh ; Muyldermans, Serge ; Schepers, Aloys ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2008)
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins.
In: Molecular & cellular proteomics : MCP, 7 (2)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
Distribution of DNA replication proteins in Drosophila cells.
In: BMC cell biology, 8
Artikel, Bibliographie

Schermelleh, Lothar ; Haemmer, Andrea ; Spada, Fabio ; Rösing, Nicole ; Meilinger, Daniela ; Rothbauer, Ulrich ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2007)
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation.
In: Nucleic acids research, 35 (13)
Artikel, Bibliographie

Agarwal, Noopur ; Hardt, Tanja ; Brero, Alessandro ; Nowak, Danny ; Rothbauer, Ulrich ; Becker, Annette ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
MeCP2 interacts with HP1 and modulates its heterochromatin association during myogenic differentiation.
In: Nucleic acids research, 35 (16)
Artikel, Bibliographie

Tünnemann, Gisela ; Karczewski, Peter ; Haase, Hannelore ; Cardoso, M. Cristina ; Morano, Ingo (2007)
Modulation of muscle contraction by a cell-permeable peptide.
In: Journal of molecular medicine, 85 (12)
Artikel, Bibliographie

Martin, Robert M. ; Tünnemann, Gisela ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
Nucleolar marker for living cells.
In: Histochemistry and cell biology, 127 (3)
Artikel, Bibliographie

Martin, Robert M. ; Görisch, Sabine M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2007)
An unexpected link between energy metabolism, calcium, chromatin condensation and cell cycle.
In: Cell cycle (Georgetown, Tex.), 6 (19)
Artikel, Bibliographie

Tünnemann, Gisela ; Martin, Robert M. ; Haupt, Simone ; Patsch, Christoph ; Edenhofer, Frank ; Cardoso, M. Cristina (2006)
Cargo-dependent mode of uptake and bioavailability of TAT-containing proteins and peptides in living cells.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (11)
Artikel, Bibliographie

Mortusewicz, Oliver ; Rothbauer, Ulrich ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2006)
Differential recruitment of DNA Ligase I and III to DNA repair sites.
In: Nucleic acids research, 34 (12)
Artikel, Bibliographie

Haase, Hannelore ; Dobbernack, Gisela ; Tünnemann, Gisela ; Karczewski, Peter ; Cardoso, M. Cristina ; Petzhold, Daria ; Schlegel, Wolfgang-Peter ; Lutter, Steffen ; Pierschalek, Petra ; Behlke, Joachim ; Morano, Ingo (2006)
Minigenes encoding N-terminal domains of human cardiac myosin light chain-1 improve heart function of transgenic rats.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20 (7)
Artikel, Bibliographie

Brero, A. ; Leonhardt, H. ; Cardoso, M. Cristina (2006)
Replication and translation of epigenetic information.
In: Current topics in microbiology and immunology, 301
Artikel, Bibliographie

Weidtkamp-Peters, Stefanie ; Rahn, Hans-Peter ; Cardoso, M. Cristina ; Hemmerich, Peter (2006)
Replication of centromeric heterochromatin in mouse fibroblasts takes place in early, middle, and late S phase.
In: Histochemistry and cell biology, 125 (1-2)
Artikel, Bibliographie

Perucca, Paola ; Cazzalini, Ornella ; Mortusewicz, Oliver ; Necchi, Daniela ; Savio, Monica ; Nardo, Tiziana ; Stivala, Lucia A. ; Leonhardt, Heinrich ; Cardoso, M. Cristina ; Prosperi, Ennio (2006)
Spatiotemporal dynamics of p21CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen.
In: Journal of cell science, 119 (Pt 8)
Artikel, Bibliographie

Rothbauer, Ulrich ; Zolghadr, Kourosh ; Tillib, Sergei ; Nowak, Danny ; Schermelleh, Lothar ; Gahl, Anja ; Backmann, Natalija ; Conrath, Katja ; Muyldermans, Serge ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2006)
Targeting and tracing antigens in live cells with fluorescent nanobodies.
In: Nature methods, 3 (11)
Artikel, Bibliographie

Jambor de Sousa, Ulrike L. ; Koss, Michael D. ; Fillies, Marion ; Gahl, Anja ; Scheeder, Martin R L. ; Cardoso, M. Cristina ; Leonhardt, Heinrich ; Geary, Nori ; Langhans, Wolfgang ; Leonhardt, Monika (2005)
CPT1alpha over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells.
In: Biochemical and biophysical research communications, 338 (2)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
Cell cycle markers for live cell analyses.
In: Cell cycle (Georgetown, Tex.), 4 (3)
Artikel, Bibliographie

Martin, Robert M. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
DNA labeling in living cells.
In: Cytometry. Part A, 67 (1)
Artikel, Bibliographie

Grünwald, D. ; Cardoso, M. Cristina ; Leonhardt, H. ; Buschmann, V. (2005)
Diffusion and binding properties investigated by Fluorescence Correlation Spectroscopy (FCS).
In: Current pharmaceutical biotechnology, 6 (5)
Artikel, Bibliographie

Brero, Alessandro ; Easwaran, Hariharan P. ; Nowak, Danny ; Grunewald, Ingrid ; Cremer, Thomas ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
Methyl CpG-binding proteins induce large-scale chromatin reorganization during terminal differentiation.
In: The Journal of cell biology, 169 (5)
Artikel, Bibliographie

Sporbert, Anje ; Domaing, Petra ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2005)
PCNA acts as a stationary loading platform for transiently interacting Okazaki fragment maturation proteins.
In: Nucleic acids research, 33 (11)
Artikel, Bibliographie

Mortusewicz, Oliver ; Schermelleh, Lothar ; Walter, Joachim ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Recruitment of DNA methyltransferase I to DNA repair sites.
In: Proceedings of the National Academy of Sciences of the United States of America, 102 (25)
Artikel, Bibliographie

Grohmann, Maik ; Spada, Fabio ; Schermelleh, Lothar ; Alenina, Natalia ; Bader, Michael ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Restricted mobility of Dnmt1 in preimplantation embryos: implications for epigenetic reprogramming.
In: BMC developmental biology, 5
Artikel, Bibliographie

Schermelleh, Lothar ; Spada, Fabio ; Easwaran, Hariharan P. ; Zolghadr, Kourosh ; Margot, Jean B. ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2005)
Trapped in action: direct visualization of DNA methyltransferase activity in living cells.
In: Nature methods, 2 (10)
Artikel, Bibliographie

Solomon, David A. ; Cardoso, M. Cristina ; Knudsen, Erik S. (2004)
Dynamic targeting of the replication machinery to sites of DNA damage.
In: The Journal of cell biology, 166 (4)
Artikel, Bibliographie

Angus, Steven P. ; Mayhew, Christopher N. ; Solomon, David A. ; Braden, Wesley A. ; Markey, Michael P. ; Okuno, Yukiko ; Cardoso, M. Cristina ; Gilbert, David M. ; Knudsen, Erik S. (2004)
RB reversibly inhibits DNA replication via two temporally distinct mechanisms.
In: Molecular and cellular biology, 24 (12)
Artikel, Bibliographie

Easwaran, Hariharan P. ; Schermelleh, Lothar ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2004)
Replication-independent chromatin loading of Dnmt1 during G2 and M phases.
In: EMBO reports, 5 (12)
Artikel, Bibliographie

Sadoni, Nicolas ; Cardoso, M. Cristina ; Stelzer, Ernst H. K. ; Leonhardt, Heinrich ; Zink, Daniele (2004)
Stable chromosomal units determine the spatial and temporal organization of DNA replication.
In: Journal of cell science, 117 (Pt 22)
Artikel, Bibliographie

Choi, Mira ; Rolle, Susanne ; Wellner, Maren ; Cardoso, M. Cristina ; Scheidereit, Claus ; Luft, Friedrich C. ; Kettritz, Ralph (2003)
Inhibition of NF-kappaB by a TAT-NEMO-binding domain peptide accelerates constitutive apoptosis and abrogates LPS-delayed neutrophil apoptosis.
In: Blood, 102 (6)
Artikel, Bibliographie

Cardoso, M. Cristina (2003)
Law and order in the nucleus.
In: Zellbiologie aktuell, 29 (3)
Artikel, Bibliographie

Sporbert, Anje ; Gahl, Anja ; Ankerhold, Richard ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2002)
DNA polymerase clamp shows little turnover at established replication sites but sequential de novo assembly at adjacent origin clusters.
In: Molecular cell, 10 (6)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, Heinrich (2002)
Protein transduction: a novel tool for tissue regeneration.
In: Biological chemistry, 383 (10)
Artikel, Bibliographie

Quensel, Christina ; Krämer, Jochen ; Cardoso, M. Cristina ; Leonhardt, Heinrich (2002)
Smoothelin contains a novel actin cytoskeleton localization sequence with similarity to troponin T.
In: Journal of cellular biochemistry, 85 (2)
Artikel, Bibliographie

Derer, Wolfgang ; Easwaran, Hariharan P. ; Leonhardt, Heinrich ; Cardoso, M. Cristina (2002)
A novel approach to induce cell cycle reentry in terminally differentiated muscle cells.
In: The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 16 (1)
Artikel, Bibliographie

Krämer, Jochen ; Quensel, Christina ; Meding, J. ; Cardoso, M. Cristina ; Leonhardt, H. (2001)
Identification and characterization of novel smoothelin isoforms in vascular smooth muscle.
In: Journal of vascular research, 38 (2)
Artikel, Bibliographie

Margot, J. B. ; Cardoso, M. Cristina ; Leonhardt, H. (2001)
Mammalian DNA methyltransferases show different subnuclear distributions.
In: Journal of cellular biochemistry, 83 (3)
Artikel, Bibliographie

Leonhardt, H. ; Cardoso, M. Cristina (2000)
DNA methylation, nuclear structure, gene expression and cancer.
In: Journal of cellular biochemistry, 79 (S35)
Artikel, Bibliographie

Leonhardt, H. ; Rahn, H. P. ; Weinzierl, P. ; Sporbert, A. ; Cremer, T. ; Zink, D. ; Cardoso, M. Cristina (2000)
Dynamics of DNA replication factories in living cells.
In: The Journal of cell biology, 149 (2)
Artikel, Bibliographie

Aguirre-Arteta, A. M. ; Grunewald, I. ; Cardoso, M. Cristina ; Leonhardt, H. (2000)
Expression of an alternative Dnmt1 isoform during muscle differentiation.
In: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 11 (10)
Artikel, Bibliographie

Margot, J. B. ; Aguirre-Arteta, A. M. ; Di Giacco, B. V. ; Pradhan, S. ; Roberts, R. J. ; Cardoso, M. Cristina ; Leonhardt, H. (2000)
Structure and function of the mouse DNA methyltransferase gene: Dnmt1 shows a tripartite structure.
In: Journal of molecular biology, 297 (2)
Artikel, Bibliographie

Leonhardt, H. ; Sporbert, A. ; Cardoso, M. Cristina (2000)
Targeting regulatory factors to intranuclear replication sites.
In: Critical reviews in eukaryotic gene expression, 10 (2)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. (1999)
DNA methyltransferase is actively retained in the cytoplasm during early development.
In: The Journal of cell biology, 147 (1)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H.
Hrsg.: Stein, G. ; Baserga, R. ; Denhardt, D. ; Giordano, A. (1999)
Differentiation, development and programmed cell death.
In: The Molecular Basis of Cell Cycle and Growth Control
Buchkapitel, Bibliographie

Derer, W ; Easwaran, H. P. ; Knopf, C. W. ; Leonhardt, H. ; Cardoso, M. Cristina (1999)
Direct protein transfer to terminally differentiated muscle cells.
In: Journal of molecular medicine, 77 (8)
Artikel, Bibliographie

Lee-Kirsch, M. A. ; Gaudet, F. ; Cardoso, M. Cristina ; Lindpaintner, K. (1999)
Distinct renin isoforms generated by tissue-specific transcription initiation and alternative splicing.
In: Circulation research, 84 (2)
Artikel, Bibliographie

Harsdorf, R. von ; Hauck, L. ; Mehrhof, F. ; Wegenka, U. ; Cardoso, M. Cristina ; Dietz, R. (1999)
E2F-1 overexpression in cardiomyocytes induces downregulation of p21CIP1 and p27KIP1 and release of active cyclin-dependent kinases in the presence of insulin-like growth factor I.
In: Circulation research, 85 (2)
Artikel, Bibliographie

Leonhardt, H. ; Rahn, H. P. ; Cardoso, M. Cristina (1999)
Functional links between nuclear structure, gene expression, DNA replication, and methylation.
In: Critical reviews in eukaryotic gene expression, 9 (3-4)
Artikel, Bibliographie

Cardoso, M. Cristina ; Sporbert, A. ; Leonhardt, H. (1999)
Structure and function in the nucleus: subnuclear trafficking of DNA replication factors.
In: Journal of cellular biochemistry, 75 (S32)
Artikel, Bibliographie

Engel, F. B. ; Hauck, L. ; Cardoso, M. Cristina ; Leonhardt, H. ; Dietz, R. ; Harsdorf, R. von (1999)
A mammalian myocardial cell-free system to study cell cycle reentry in terminally differentiated cardiomyocytes.
In: Circulation research, 85 (3)
Artikel, Bibliographie

Krämer, J. ; Aguirre-Arteta, A. M. ; Thiel, C. ; Gross, C. M. ; Dietz, R. ; Cardoso, M. Cristina ; Leonhardt, H. (1999)
A novel isoform of the smooth muscle cell differentiation marker smoothelin.
In: Journal of molecular medicine, 77 (2)
Artikel, Bibliographie

Leonhardt, H. ; Rahn, H. P. ; Cardoso, M. Cristina (1998)
Intranuclear targeting of DNA replication factors.
In: Journal of cellular biochemistry, 72 (S30-31)
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. (1998)
Protein targeting to subnuclear higher order structures: a new level of regulation and coordination of nuclear processes.
In: Journal of cellular biochemistry, 70 (2)
Artikel, Bibliographie

Cardoso, M. Cristina ; Joseph, C. ; Rahn, H. P. ; Reusch, R. ; Nadal-Ginard, B. ; Leonhardt, H. (1997)
Mapping and use of a sequence that targets DNA ligase I to sites of DNA replication in vivo.
In: The Journal of cell biology, 139 (3)
Artikel, Bibliographie

Leonhardt, H. ; Cardoso, M. Cristina (1996)
Targeting and association of proteins with functional domains in the nucleus: the insoluble solution.
In: International review of cytology, 162 (Part B)
doi: 10.1016/S0074-7696(08)62620-0
Artikel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H.
Hrsg.: Pagano, M. (1995)
Immunofluorescence techniques in cell cycle studies.
In: Cell Cycle: Materials and Methods
Buchkapitel, Bibliographie

Cardoso, M. Cristina ; Leonhardt, H. ; Nadal-Ginard, B. (1993)
Reversal of terminal differentiation and control of DNA replication: cyclin A and Cdk2 specifically localize at subnuclear sites of DNA replication.
In: Cell, 74 (6)
Artikel, Bibliographie

McDermott, J. C. ; Cardoso, M. Cristina ; Yu, Y. T. ; Andres, V. ; Leifer, D. ; Krainc, D. ; Lipton, S. A. ; Nadal-Ginard, B. (1993)
hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.
In: Molecular and cellular biology, 13 (4)
Artikel, Bibliographie