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A journey through the microscopic ages of DNA replication.

Reinhart, Marius ; Cardoso, M. Cristina (2017)
A journey through the microscopic ages of DNA replication.
In: Protoplasma, 254 (3)
Artikel, Bibliographie

Kurzbeschreibung (Abstract)

Scientific discoveries and technological advancements are inseparable but not always take place in a coherent chronological manner. In the next, we will provide a seemingly unconnected and serendipitous series of scientific facts that, in the whole, converged to unveil DNA and its duplication. We will not cover here the many and fundamental contributions from microbial genetics and in vitro biochemistry. Rather, in this journey, we will emphasize the interplay between microscopy development culminating on super resolution fluorescence microscopy (i.e., nanoscopy) and digital image analysis and its impact on our understanding of DNA duplication. We will interlace the journey with landmark concepts and experiments that have brought the cellular DNA replication field to its present state.

Typ des Eintrags: Artikel
Erschienen: 2017
Autor(en): Reinhart, Marius ; Cardoso, M. Cristina
Art des Eintrags: Bibliographie
Titel: A journey through the microscopic ages of DNA replication.
Sprache: Englisch
Publikationsjahr: 2017
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Protoplasma
Jahrgang/Volume einer Zeitschrift: 254
(Heft-)Nummer: 3
Kurzbeschreibung (Abstract):

Scientific discoveries and technological advancements are inseparable but not always take place in a coherent chronological manner. In the next, we will provide a seemingly unconnected and serendipitous series of scientific facts that, in the whole, converged to unveil DNA and its duplication. We will not cover here the many and fundamental contributions from microbial genetics and in vitro biochemistry. Rather, in this journey, we will emphasize the interplay between microscopy development culminating on super resolution fluorescence microscopy (i.e., nanoscopy) and digital image analysis and its impact on our understanding of DNA duplication. We will interlace the journey with landmark concepts and experiments that have brought the cellular DNA replication field to its present state.

ID-Nummer: pmid:27943022
Fachbereich(e)/-gebiet(e): 10 Fachbereich Biologie
10 Fachbereich Biologie > Cell Biology and Epigenetics
Hinterlegungsdatum: 04 Jan 2017 11:16
Letzte Änderung: 09 Mai 2017 07:30
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