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Anzahl der Einträge: 154.

Layer, Paul G. (2024)
In a century from agitated cells to human organoids.
In: Journal of neuroscience methods
doi: 10.1016/j.jneumeth.2024.110083
Artikel, Bibliographie

Luo, Xiaohe ; Lauwers, Marianne ; Layer, Paul G. ; Wen, Chunyi (2021)
Non-neuronal Role of Acetylcholinesterase in Bone Development and Degeneration.
In: Frontiers in cell and developmental biology, 8
doi: 10.3389/fcell.2020.620543
Artikel, Bibliographie

Frohns, Florian ; Frohns, Antonia ; Kramer, Johanna ; Meurer, Katharina ; Rohrer-Bley, Carla ; Solovei, Irina ; Hicks, David ; Layer, Paul G. ; Löbrich, Markus (2021)
Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans.
In: Cells, 2020, 9 (4)
doi: 10.26083/tuprints-00019030
Artikel, Zweitveröffentlichung, Verlagsversion

Frohns, Florian ; Frohns, Antonia ; Kramer, Johanna ; Meurer, Katharina ; Rohrer-Bley, Carla ; Solovei, Irina ; Hicks, David ; Layer, Paul G. ; Löbrich, Markus (2020)
Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans.
In: Cells, 9 (4)
doi: 10.3390/cells9040947
Artikel, Bibliographie

Spieker, Janine ; Frieß, Johannes L. ; Sperling, Laura ; Thangaraj, Gopenath ; Vogel-Höpker, A. ; Layer, Paul G. (2020)
Cholinergic control of bone development and beyond.
In: International immunopharmacology, 83
doi: 10.1016/j.intimp.2020.106405
Artikel, Bibliographie

Bachmann, Gesine ; Frohns, Florian ; Thangaraj, Gopenath ; Bausch, Alexander ; Layer, Paul G. (2019)
IPL Sublamination in Chicken Retinal Spheroids Is Initiated via Müller Cells and Cholinergic Differentiation, and Is Disrupted by NMDA Signaling.
In: Investigative ophthalmology & visual science, 60 (14)
doi: 10.1167/iovs.18-24952
Artikel, Bibliographie

Shirahama, Misaki ; Steinfeld, Ichie ; Karaiwa, Akari ; Taketani, Shigeru ; Vogel-Höpker, A. ; Layer, Paul G. ; Araki, Masasuke (2019)
Change in the developmental fate of the chick optic vesicle from the neural retina to the telencephalon.
In: Development, Growth & Differentiation, 61 (3)
doi: 10.1111/dgd.12599
Artikel, Bibliographie

Heselich, Anja ; Frieß, Johannes L. ; Ritter, Sylvia ; Benz, Naja P. ; Layer, Paul G. ; Thielemann, Christiane (2018)
High LET radiation shows no major cellular and functional effects on primary cardiomyocytes in vitro.
In: Life sciences in space research, 16
Artikel, Bibliographie

Thomsen, Andreas R. ; Aldrian, Christine ; Bronsert, Peter ; Thomann, Yi ; Nanko, Norbert ; Melin, Nicolas ; Rücker, Gerta ; Follo, Marie ; Grosu, Anca L. ; Niedermann, Gabriele ; Layer, Paul G. ; Heselich, Anja ; Lund, Per G. (2018)
A deep conical agarose microwell array for adhesion independent three-dimensional cell culture and dynamic volume measurement.
In: Lab on a chip, 18 (1)
Artikel, Bibliographie

König, Anke ; Zöller, Nadja ; Kippenberger, Stefan ; Bernd, August ; Kaufmann, Roland ; Layer, Paul G. ; Heselich, Anja (2017)
Non-thermal near-infrared exposure photobiomodulates cellular responses to ionizing radiation in human full thickness skin models.
In: Journal of photochemistry and photobiology. B, Biology, 178
Artikel, Bibliographie

Steinfeld, Jörg ; Steinfeld, Ichie ; Bausch, Alexander ; Coronato, Nicola ; Hampel, Meggi-Lee ; Depner, Heike ; Layer, Paul G. ; Vogel-Höpker, A. (2017)
BMP-induced reprogramming of the neural retina into retinal pigment epithelium requires Wnt signalling.
In: Biology open, 6 (7)
Artikel, Bibliographie

Spieker, Janine ; Mudersbach, Thomas ; Vogel-Höpker, A. ; Layer, Paul G. (2017)
Endochondral Ossification Is Accelerated in Cholinesterase-Deficient Mice and in Avian Mesenchymal Micromass Cultures.
In: PloS one, 2017, 12 (1)
doi: 10.1371/journal.pone.0170252
Artikel, Zweitveröffentlichung

König, Anke ; Heselich, Anja ; Zöller, N. ; Kaufmann, R. ; Kippenberger, S. ; Layer, Paul G. (2017)
Evaluation of the radiation-induced stress response in a human full thickness skin model.
In: Experimental dermatology, 26 (3)
Artikel, Bibliographie

Spieker, Janine ; Ackermann, Anica ; Salfelder, Anika ; Vogel-Höpker, A. ; Layer, Paul G. (2016)
Acetylcholinesterase Regulates Skeletal In Ovo Development of Chicken Limbs by ACh-Dependent and -Independent Mechanisms.
In: PloS one, 11 (8)
Artikel, Bibliographie

Mayer, Margot ; Kaiser, Nicole ; Layer, Paul G. ; Frohns, Florian (2016)
Cell Cycle Regulation and Apoptotic Responses of the Embryonic Chick Retina by Ionizing Radiation.
In: PloS one, 11 (5)
Artikel, Bibliographie

Simoniello, Palma ; Wiedemann, Julia ; Zink, Joana ; Thoennes, Eva ; Stange, Maike ; Layer, Paul G. ; Kovacs, Maximilian ; Podda, Maurizio ; Durante, Marco ; Fournier, Claudia (2016)
Exposure to carbon ions triggers proinflammatory signals and changes in homeostasis and epidermal tissue organization to a similar extent as photons.
In: Frontiers in oncology, 5
doi: 10.3389/fonc.2015.00294
Artikel, Bibliographie

Thangaraj, Gopenath ; Manakov, Vadim ; Cucu, Aljona ; Fournier, Claudia ; Layer, Paul G. (2016)
Inflammatory effects of TNFα are counteracted by X-ray irradiation and AChE inhibition in mouse micromass cultures.
In: Chemico-biological interactions, 259 (Pt. B)
Artikel, Bibliographie

Frieß, Johannes L. ; Heselich, Anja ; Ritter, Sylvia ; Haber, Angelina ; Kaiser, Nicole ; Layer, Paul G. ; Thielemann, Christiane (2015)
Electrophysiologic and cellular characteristics of cardiomyocytes after X-ray irradiation.
In: Mutation research, 777
Artikel, Bibliographie

Thangaraj, Gopenath ; Christophel, Jeanette ; Bachmann, Gesine ; Greif, Alexander ; Layer, Paul G. (2015)
PEDF counteracts DL-α-aminoadipate toxicity and rescues gliotoxic damages in RPE-free chicken retinal explants.
In: Experimental eye research, 134
doi: 10.1016/j.exer.2015.02.010
Artikel, Bibliographie

Frieß, Johannes ; Heselich, Anja ; Ritter, Sylvia ; Layer, Paul G. ; Thielemann, Christiane (2014)
Electrophysiologic and molecular characteristics of cardiomyocytes after heavy ion irradiation in the frame of the ESA IBER-10 program.
In: Journal of radiation research, 55 (Suppl 1)
Artikel, Bibliographie

Frohns, Antonia ; Frohns, Florian ; Naumann, Steffen C. ; Layer, Paul G. ; Löbrich, Markus (2014)
Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin Organization.
In: Current biology : CB, 24 (10)
Artikel, Bibliographie

Bodur, Ebru ; Layer, Paul G. (2014)
PKC stimulation increases expression of cholinesterases in R28 cell line.
In: Turkish Journal of Biochemistry - Turk Biyokimya Dergisi, 39 (2)
Artikel, Bibliographie

Layer, Paul G. ; Klaczinski, Janine ; Salfelder, Anika ; Sperling, Laura E. ; Thangaraj, Gopenath ; Tuschl, Corina ; Vogel-Höpker, A. (2013)
Cholinesterases in development: AChE as a firewall to inhibit cell proliferation and support differentiation.
In: Chemico-biological interactions, 203 (1)
Artikel, Bibliographie

Layer, Paul G. ; Klaczinski, Janine ; Vogel-Höpker, A. ; Thangaraj, Gopenath (2013)
Developmental cholinergic mechanism : Do not forget the colinesterases!
In: Autonomic neuroscience : basic and clinical, 177
doi: 10.1016/j.autneu.2013.05.102
Artikel, Bibliographie

Steinfeld, Jörg ; Steinfeld, Ichie ; Coronato, Nicola ; Hampel, Meggi-Lee ; Layer, Paul G. ; Araki, Masasuke ; Vogel-Höpker, A. (2013)
RPE specification in the chick is mediated by surface ectoderm-derived BMP and Wnt signalling.
In: Development (Cambridge, England), 140 (24)
Artikel, Bibliographie

Vogel-Höpker, A. ; Sperling, Laura E. ; Layer, Paul G. (2012)
Co-opting functions of cholinesterases in neural, limb and stem cell development.
In: Protein and peptide letters, 19 (2)
Artikel, Bibliographie

Thangaraj, Gopenath ; Greif, Alexander ; Bachmann, Gesine ; Layer, Paul G. (2012)
Intricate paths of cells and networks becoming "Cholinergic" in the embryonic chicken retina.
In: The Journal of comparative neurology, 520 (14)
Artikel, Bibliographie

Sperling, Laura E. ; Klaczinski, Janine ; Schütz, Corina ; Rudolph, Lydia ; Layer, Paul G. (2012)
Mouse acetylcholinesterase enhances neurite outgrowth of rat r28 cells through interaction with laminin-1.
In: PloS one, 7 (5)
Artikel, Bibliographie

Heselich, Anja ; Frohns, Florian ; Frohns, Antonia ; Naumann, Steffen C. ; Layer, Paul G. (2012)
Near-infrared exposure changes cellular responses to ionizing radiation.
In: Photochemistry and photobiology, 88 (1)
Artikel, Bibliographie

Daus, Andreas W. ; Layer, Paul G. ; Thielemann, Christiane (2012)
A spheroid-based biosensor for the label-free detection of drug-induced field potential alterations.
In: Sensors and actuators B: Chemical, 165 (1)
Artikel, Bibliographie

Bodur, Ebru ; Layer, Paul G. (2011)
Counter-regulation of cholinesterases: differential activation of PKC and ERK signaling in retinal cells through BChE knockdown.
In: Biochimie, 93 (3)
Artikel, Bibliographie

Daus, Andreas W. ; Goldhammer, Michael ; Layer, Paul G. ; Thielemann, Christiane (2011)
Electromagnetic exposure of scaffold-free three-dimensional cell culture systems.
In: Bioelectromagnetics, 32 (5)
Artikel, Bibliographie

Berchtold, Doris ; Fesser, Stephanie ; Bachmann, Gesine ; Kaiser, Alexander ; Eilert, John-Christian ; Frohns, Florian ; Sadoni, Nicolas ; Muck, Joscha ; Kremmer, Elisabeth ; Eick, Dirk ; Layer, Paul G. ; Zink, Daniele (2011)
Nuclei of chicken neurons in tissues and three-dimensional cell cultures are organized into distinct radial zones.
In: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 19 (2)
Artikel, Bibliographie

Thangaraj, Gopenath ; Greif, Alexander ; Layer, Paul G. (2011)
Simple explant culture of the embryonic chicken retina with long-term preservation of photoreceptors.
In: Experimental eye research, 93 (4)
Artikel, Bibliographie

Landgraf, Dominic ; Barth, Mareike ; Layer, Paul G. ; Sperling, Laura E. (2010)
Acetylcholine as a possible signaling molecule in embryonic stem cells: studies on survival, proliferation and death.
In: Chemico-biological interactions, 187 (1-3)
Artikel, Bibliographie

Layer, Paul G. ; Araki, Masasuke ; Vogel-Höpker, A. (2010)
New concepts for reconstruction of retinal and pigment epithelial tissues.
In: Expert Review of Ophthalmology, 5 (4)
doi: 10.1586/eop.10.42
Artikel, Bibliographie

Layer, Paul G. (2009)
Wie Schlangen ihre Beine verloren : die Beziehung zwischen Evolutionstheorie und Entwicklungstheorie.
In: hoch3
Artikel, Bibliographie

Layer, Paul G. (2009)
Schlüssel zum Verständnis der Evolution : Evolutionary Theory und Developmental Biology werden kombiniert zu „EvoDevo“.
In: Darmstädter Echo, (Wissenschaftsseite)
Artikel, Bibliographie

Frohns, Florian ; Mager, Magnus ; Layer, Paul G. (2009)
Basic fibroblast growth factor increases the precursor pool of photoreceptors, but inhibits their differentiation and apoptosis in chicken retinal reaggregates.
In: The European journal of neuroscience, 29 (10)
Artikel, Bibliographie

Layer, Paul G. (2009)
Doppelkopf und Schrumpfbein : Evolutionsspiele im Embryo.
In: labor&more, (5)
Artikel, Bibliographie

Rajesh, Ramanna V. ; Layer, Paul G. ; Boopathy, Rathanam (2009)
High aryl acylamidase activity associated with cobra venom acetylcholinesterase: biological significance.
In: Biochimie, 91 (11-12)
Artikel, Bibliographie

Volpert, Katja N. ; Tombran-Tink, Joyce ; Barnstable, Colin ; Layer, Paul G. (2009)
PEDF and GDNF are key regulators of photoreceptor development and retinal neurogenesis in reaggregates from chick embryonic retina.
In: Journal of ocular biology, diseases, and informatics, 2 (1)
Artikel, Bibliographie

Rajesh, Ramanna V. ; Chitra, Loganathan ; Layer, Paul G. ; Boopathy, Rathanam (2009)
The aryl acylamidase activity is much more sensitive to Alzheimer drugs than the esterase activity of acetylcholinesterase in chicken embryonic brain.
In: Biochimie, 91 (9)
Artikel, Bibliographie

Layer, Paul G.
Hrsg.: Souvignier, Georg (2009)
Über Freiheiten des Menschen: mit dem Gehirn zur Welt- und dann zur Gotterkenntnis.
In: Gottesbilder : an der Grenze zwischen Naturwissenschaft und Theologie
Buchkapitel, Bibliographie

Layer, Paul G. (2008)
Vom Überlebenskampf von Rassen und Genen : Darwins Abstammungslehre weltanschaulich instrumentalisiert vom Dritten Reich bis heute : Vortrag in der Odenwald-Akademie in der Synagoge Michelstadt am 13.03.2008.
Michelstadt (13.03.2008)
Konferenzveröffentlichung, Bibliographie

Paraoanu, Laura E. ; Layer, Paul G. (2008)
Acetylcholinesterase in cell adhesion, neurite growth and network formation.
In: The FEBS journal, 275 (4)
Artikel, Bibliographie

Sperling, L. E. ; Steinert, G. ; Boutter, J. ; Landgraf, D. ; Hescheler, J. ; Pollet, D. ; Layer, Paul G. (2008)
Characterisation of cholinesterase expression during murine embryonic stem cell differentiation.
In: Chemico-biological interactions, 175 (1-3)
Artikel, Bibliographie

Rieke, Matthias ; Gottwald, Eric ; Weibezahn, Karl-Friedrich ; Layer, Paul G. (2008)
Tissue reconstruction in 3D-spheroids from rodent retina in a motion-free, bioreactor-based microstructure.
In: Lab on a chip, 8 (12)
Artikel, Bibliographie

Bytyqi, Afrim H. ; Bachmann, Gesine ; Rieke, Matthias ; Paraoanu, Laura E. ; Layer, Paul G. (2007)
Cell-by-cell reconstruction in reaggregates from neonatal gerbil retina begins from the inner retina and is promoted by retinal pigmented epithelium.
In: The European journal of neuroscience, 26 (6)
Artikel, Bibliographie

Paraoanu, Laura E. ; Steinert, Gunnar ; Koehler, Alexander ; Wessler, Ignaz ; Layer, Paul G. (2007)
Expression and possible functions of the cholinergic system in a murine embryonic stem cell line.
In: Life sciences, 80 (24-25)
Artikel, Bibliographie

Volpert, Katja N. ; Rothermel, Andrée ; Layer, Paul G. (2007)
GDNF stimulates rod photoreceptors and dopaminergic amacrine cells in chicken retinal reaggregates.
In: Investigative ophthalmology & visual science, 48 (11)
Artikel, Bibliographie

Boopathy, Rathanam ; Rajesh, Ramanna Valmiki ; Darvesh, Sultan ; Layer, Paul G. (2007)
Human serum cholinesterase from liver pathological samples exhibit highly elevated aryl acylamidase activity.
In: Clinica chimica acta; international journal of clinical chemistry, 380 (1-2)
Artikel, Bibliographie

Paraoanu, Laura E. ; Mocko, J. B. ; Becker-Roeck, Michaela ; Smidek-Huhn, Jutta ; Layer, Paul G. (2006)
Exposure to diazinon alters in vitro retinogenesis : retinospheroid morphology, development of chicken retinal cell types and gene expression.
In: Toxicological sciences, 89
Artikel, Bibliographie

Paraoanu, Laura E. ; Christ, Elmar ; Becker-Roeck, Michaela ; Layer, Paul G. (2006)
Expression patterns of neurexin-1 and neuroligins in brain and retina of the chick embryo.
In: Neuroscience letters, 3
Artikel, Bibliographie

Rothermel, Andree ; Burghardt, Mirjam ; Volpert, Katja ; Robitzki, Andrea ; Layer, Paul G. ; Lantzsch, Christina (2006)
Knock-down of GFR-alpha-4 expression by RNA interference affects the development of retinal cell types in three-dimensional histotypic retinal spheres.
In: Investigative ophthalmology & visual science, 47 (6)
Artikel, Bibliographie

Layer, Paul G. (2006)
Leichtes Bauen in der Natur.
In: Thema Forschung
Artikel, Bibliographie

Manoharan, Indumathi ; Wieseler, Stacy ; Layer, Paul G. ; Lockridge, Oksana ; Boopathy, Rathanam (2006)
Naturally occurring mutation Leu307Pro of human butyrylcholinesterase in the Vysya community of India.
In: Pharmacogenetics and genomics, 16 (7)
Artikel, Bibliographie

Paraoanu, Laura E. ; Steinert, G. ; Klaczinski, J. ; Becker-Roeck, Michaela ; Bytyqi, Afrim H. ; Layer, Paul G. (2006)
On functions of cholinesterases during embryonic development.
In: Journal of molecular neuroscience, 30 (1-2)
Artikel, Bibliographie

Rothermel, Andree ; Biedermann, Thomas ; Weigel, Winnie ; Kurz, Randy ; Rüffer, Markus ; Layer, Paul G. ; Robitzki, Andrea (2005)
Artificial design of three-dimensional retina-like tissue from dissociated cells of the mammalian retina by rotation-mediated cell aggregation.
In: Tissue engineering, 11 (11-12)
Artikel, Bibliographie

Paraoanu, Laura E. ; Weiss, B. ; Layer, Paul G. (2005)
Cytochrome-c oxidase is one of several genes elevated in marginal retina of the chick embryo.
In: Neuroscience, 132
Artikel, Bibliographie

Allebrandt, Karla V. ; Rajesh, Valmiki ; Layer, Paul G. (2005)
Expression of acetylcholinesterase (AChE) and aryl acylamidase (AAA) during early zebrafish embryogenesis.
In: Chemico-biological interactions, 157-158
Artikel, Bibliographie

Aluigi, M. G. ; Angelini, C. ; Falugi, C. ; Fossa, R. ; Genever, P. ; Gallus, L. ; Layer, Paul G. ; Prestipino, G. ; Rakonczay, Z. ; Sgro, M. ; Thielecke, H. ; Trombino, S. (2005)
Interaction between organophosphate compounds and cholinergic functions during development.
In: Chemico-biological interactions, 1
Artikel, Bibliographie

Bytyqi, Afrim H. ; Layer, Paul G. (2005)
Lamina formation in the Mongolian gerbil retina (Meriones unguiculatus).
In: Anatomy & embryology, 209 (3)
Artikel, Bibliographie

Layer, Paul G.
Hrsg.: Rossmann, Torsten ; Tropea, Cameron (2005)
Mit Stammzellen und Tissue Engineering zu Netzhautimplantaten.
In: Bionik : aktuelle Forschungsergebnisse in Natur-, Ingenieur- und Geisteswissenschaft
Buchkapitel, Bibliographie

Paraoanu, Laura E. ; Layer, Paul G. (2005)
Mouse AChE binds in vivo to domain IV of laminin-1beta.
In: Chemico-biological interactions, 157-158
Artikel, Bibliographie

Layer, Paul G. ; Allebrandt, Karla V. ; Andermann, P. ; Bodur, E. ; Boopathy, Rathanam ; Bytyqi, Afrim H. ; Paraoanu, Laura E. (2005)
On the multifunctionally of cholinesterases.
In: Chemico-biological interactions, 157 (15)
Artikel, Bibliographie

Jacob, V. ; Rothermel, Andree ; Wolf, Peter ; Layer, Paul G. (2005)
Rhodopsin, violet and blue opsin expressions in the chick are highly dependent on tissue and serum conditions.
In: Cells tissues organs, 180 (3)
Artikel, Bibliographie

Layer, Paul G. (2005)
Vernünftiges und vernünftig Vermutetes zu Gehirn, Geist und Gott.
In: Gott - Geist - Gehirn : religiöse Erfahrungen im Lichte der neuesten Hirnforschung
Buchkapitel, Bibliographie

Boopathy, Rathanam ; Layer, Paul G. (2004)
Aryl acylamidase activity on acetylcholinesterase is high during early chicken brain development.
In: The protein journal, 23 (5)
Artikel, Bibliographie

Dabouras, Vasili ; Rothermel, Andrée ; Reiniger-Mack, Alexandra ; Wien, Sascha L. ; Layer, Paul G. ; Robitzki, Andrea (2004)
Exogenous application of glucose induces aging in rat cerebral oligodendrocytes as revealed by alteration in telomere length.
In: Neuroscience letters, 368 (1)
Artikel, Bibliographie

Seydewitz, Vera ; Rothermel, Andrée ; Fuhrmann, Sabine ; Schneider, Anikó ; De Grip, Willem J. ; Layer, Paul G. ; Hofmann, Hans-Dieter (2004)
Expression of CNTF receptor-alpha in chick violet-sensitive cones with unique morphologic properties.
In: Investigative ophthalmology & visual science, 45 (2)
Artikel, Bibliographie

Bytyqi, Afrim H. ; Lockridge, Oksana ; Duysen, Ellen ; Wang, Yuxia ; Wolfrum, Uwe ; Layer, Paul G. (2004)
Impaired formation of the inner retina in an AChE knockout mouse results in degeneration of all photoreceptors.
In: The European journal of neuroscience, 20 (11)
Artikel, Bibliographie

Paraoanu, Laura E. ; Layer, Paul G. (2004)
Mouse acetylcholinesterase interacts in yeast with the extracellular matrix component laminin-1beta.
In: FEBS letters, 576 (1-2)
Artikel, Bibliographie

Rothermel, Andrée ; Volpert, Katja ; Schlichting, Ralf ; Huhn, Jutta ; Stotz-Reimers, Meike ; Robitzki, Andrea A. ; Layer, Paul G. (2004)
Spatial and temporal expression patterns of GDNF family receptor alpha4 in the developing chicken retina.
In: Gene expression patterns : GEP, 4 (1)
Artikel, Bibliographie

Layer, Paul G.
Hrsg.: Bender, Wolfgang ; Schmidt, Jan C. (2003)
Der biomedizinische Fortschritt.
In: Zukunftsorientierte Wissenschaft : prospektive Wissenschafts- und Technikbewertung
Buchkapitel, Bibliographie

Rothermel, Andrée ; Layer, Paul G. (2003)
GDNF regulates chicken rod photoreceptor development and survival in reaggregated histotypic retinal spheres.
In: Investigative ophthalmology & visual science, 44 (5)
Artikel, Bibliographie

Naruoka, Hidenori ; Kojima, Ryosuke ; Ohmasa, Motoko ; Layer, Paul G. ; Saito, Takehiko (2003)
Transient muscarinic calcium mobilisation in transdifferentiating as in reaggregating embyronic chick retinae.
In: Developmental brain research, 143 (2)
Artikel, Bibliographie

Layer, Paul G.
Hrsg.: Schmidt, Jan C. (2003)
Zu Evolution und Entwicklung von Hirn und Bewußtsein oder: von Zellen, neuronalen Netzen und quälender Qualia.
In: Der entthronte Mensch : Anfragen der Neurowissenschaften an unser Menschenbild
Buchkapitel, Bibliographie

Willbold, Elmar ; Huhn, Jutta ; Korf, Horst-Werner ; Voisin, Pierre ; Layer, Paul G. (2002)
Light-dark and circadian melatonin rhythms are established de novo in re-aggregates of the embryonic chicken retina.
In: Developmental neuroscience, 24 (6)
Artikel, Bibliographie

Anselmet, Alain ; Mayat, Ebrahim ; Wietek, Stefan ; Layer, Paul G. ; Payrastre, Bernard ; Massoulié, Jean (2002)
Non-antisense cellular responses to oligonucleotides.
In: FEBS letters, 510 (3)
Artikel, Bibliographie

Layer, Paul G. ; Robitzki, Andrea ; Rothermel, Andrée ; Willbold, Elmar (2002)
Of layers and spheres: the reaggregate approach in tissue engineering.
In: Trends in neurosciences, 25 (3)
Artikel, Bibliographie

Layer, Paul G. ; Robitzki, Andrea (2002)
Von Stammzellen zu Gewebemodellen und Biosensoren in Medizin und Umwelttechnik.
In: Bionik : biologisch-technische Systeme. (Thema Forschung), (2)
Artikel, Bibliographie

Keller, Markus ; Robitzki, Andrea ; Layer, Paul G. (2001)
Anticholinesterase treatment of chicken retinal cells increases acetylcholinesterase protein independently of protein kinase C.
In: Neuroscience letters, 309 (1)
Artikel, Bibliographie

Willbold, Elmar ; Rothermel, A. ; Huhn, J. ; Reinicke, M. ; Layer, Paul G. (2001)
Cerebellar glia cells induce a correct laminar organization in chicken retinal reaggregates.
In: Cells tissues organs, 169 (2)
Artikel, Bibliographie

Robitzki, Andrea ; Mack, A. ; Layer, Paul G. (2001)
Die in vitro Netzhaut als Modell des zentralen Nervensystems: Entwicklung neuer Diagnostik- und Therapieformen für neurodegenerative Erkrankungen.
In: BIOforum, 24
Artikel, Bibliographie

Layer, Paul G. ; Rothermel, A. ; Willbold, E. (2001)
From stem cells towards neural layers: a lesson from re-aggregated embryonic retinal cells.
In: NeuroReport, 12
Artikel, Bibliographie

Keller, Markus ; Robitzki, Andrea ; Layer, Paul G. (2001)
Heterologous expression of acetylcholinesterase affects proliferation and glial cytoskeleton of adherent chicken retinal cells.
In: Cell and tissue research, 306
Artikel, Bibliographie

Willbold, E. ; Rothermel, A. ; Huhn, J. ; Stelck, S. ; Layer, Paul G. (2001)
Inhibition of alpha(1-6)-linked fucose decreases inner retinal cells and increases photoreceptors in chicken retinal reaggregates.
In: Developmental neuroscience, 23 (6)
Artikel, Bibliographie

Rothermel, Andrée ; Layer, Paul G. (2001)
Photoreceptor plasticity in reaggregates of embryonic chick retina: rods depend on proximal cones and on tissue organization.
In: European journal of neuroscience, 13 (5)
Artikel, Bibliographie

Willbold, E. ; Rothermel, A. ; Tomlinson, S. ; Layer, Paul G. (2000)
Müller glia cells reorganize reaggregating chicken retinal cells into correctly laminated in vitro retinae.
In: Glia, 29 (1)
Artikel, Bibliographie

Robitzki, A. ; Döll, F. ; Richter-Landsberg, C. ; Layer, Paul G. (2000)
Regulation of the rat oligodendroglia cell line OLN-93 by antisense transfection of butyrylcholinesterase.
In: Glia, 31 (3)
Artikel, Bibliographie

Weitnauer, E. ; Ebert, C. ; Hucho, F. ; Robitzki, A. ; Weise, C. ; Layer, Paul G. (1999)
Butyrylcholinesterase is complexed with transferrin in chicken serum.
In: Journal of protein chemistry, 18 (2)
Artikel, Bibliographie

Layer, Paul G. ; Robitzki, Andrea (1999)
Die Netzhaut als Hirnmodell : von der Zellkultur zur biomedizinischen Technik.
In: Thema Forschung, (2)
Artikel, Bibliographie

Stelck, S. ; Robitzki, A. ; Willbold, E. ; Layer, Paul G. (1999)
Fucose in alpha(1-6)-linkage regulates proliferation and histogenesis in reaggregated retinal spheroids of the chick embryo.
In: Glycobiology, 9 (11)
Artikel, Bibliographie

Weitnauer, E. ; Robitzki, A. ; Layer, Paul G. (1998)
Aryl acylamidase activity exhibited by butyrylcholinesterase is higher in chick than in horse, but much lower than in fetal calf serum.
In: Neuroscience letters, 254 (3)
Artikel, Bibliographie

Robitzki, A. ; Mack, A. ; Hoppe, U. ; Chatonnet, A. ; Layer, Paul G. (1998)
Butyrylcholinesterase antisense transfection increases apoptosis in differentiating retinal reaggregates of the chick embryo.
In: Journal of neurochemistry, 71 (4)
Artikel, Bibliographie

Layer, Paul G. ; Rothermel, A. ; Willbold, E. (1998)
Inductive effects of the retinal pigmented epithelium (RPE) on histogenesis of the avian retina as revealed by retinospheroid technology.
In: Seminars in cell & developmental biology, 9 (3)
Artikel, Bibliographie

Willbold, E. ; Layer, Paul G. (1998)
Müller glia cells and their possible roles during retina differentiation in vivo and in vitro.
In: Histology and histopathology, 13 (2)
Artikel, Bibliographie

Reiss, Y. ; Layer, Paul G. ; Kröger, S. (1997)
Butyrylcholinesterase-positive cells of the developing chicken retina that are non-cholinergic and GABA-positive.
In: Brain research. Developmental brain research, 100 (1)
Artikel, Bibliographie

Layer, Paul G. ; Berger, J. ; Kinkl, N. (1997)
Cholinesterases precede "ON-OFF" channel dichotomy in the embryonic chick retina before onset of synaptogenesis.
In: Cell and tissue research, 288 (3)
Artikel, Bibliographie

Willbold, E. ; Reinicke, M. ; Layer, Paul G. (1997)
Müller cell differentiation and column formation in chicken retinospheroids.
In: Journal of brain research, 36 (2)
Artikel, Bibliographie

Rothermel, A. ; Willbold, E. ; Degrip, W. J. ; Layer, Paul G. (1997)
Pigmented epithelium induces complete retinal reconstitution from dispersed embryonic chick retinae in reaggregation culture.
In: Proceedings. Biological sciences / The Royal Society, 264 (1386)
Artikel, Bibliographie

Layer, Paul G. ; Rothermel, A. ; Hering, H. ; Wolf, B. ; deGrip, W. J. ; Hicks, D. ; Willbold, E. (1997)
Pigmented epithelium sustains cell proliferation and decreases expression of opsins and acetylcholinesterase in reaggregated chicken retinospheroids.
In: The European journal of neuroscience, 9 (9)
Artikel, Bibliographie

Schober, A. ; Minichiello, L. ; Keller, M. ; Huber, K. ; Layer, Paul G. ; Roig-López, J. L. ; García-Arrarás, J. E. ; Klein, R. ; Unsicker, K. (1997)
Reduced acetylcholinesterase (AChE) activity in adrenal medulla and loss of sympathetic preganglionic neurons in TrkA-deficient, but not TrkB-deficient, mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 17 (3)
Artikel, Bibliographie

Robitzki, A. ; Mack, A. ; Hoppe, U. ; Chatonnet, A. ; Layer, Paul G. (1997)
Regulation of cholinesterase gene expression affects neuronal differentiation as revealed by transfection studies on reaggregating embryonic chicken retinal cells.
In: The European journal of neuroscience, 9 (11)
Artikel, Bibliographie

Robitzki, A. ; Mack, A. ; Chatonnet, A. ; Layer, Paul G. (1997)
Transfection of reaggregating embryonic chicken retinal cells with an antisense 5'-DNA butyrylcholinesterase expression vector inhibits proliferation and alters morphogenesis.
In: Journal of neurochemistry, 69 (2)
Artikel, Bibliographie

Reiss, Y. ; Kröger, S. ; Grassi, J. ; Tsim, K. W. ; Willbold, E. ; Layer, Paul G. (1996)
Extracellular and asymmetric forms of acetylcholinesterase are expressed on cholinergic and noncholinergic terminal neuropil of the developing chick retina.
In: Cell and tissue research, 286 (1)
Artikel, Bibliographie

Willbold, Elmar ; Mansky, P. ; Layer, Paul G. (1996)
Lateral and radial growth uncoupled in reaggregated retinospheroids of embryonic avian retina.
In: International journal of developmental biology, 40 (6)
Artikel, Bibliographie

Layer, Paul G. (1996)
Non-classical actions of cholinesterases: role in cellular differentiation, tumorigenesis and Alzheimer's disease.
In: Neurochemistry international, 28 (5-6)
Artikel, Bibliographie

Weiss, Bettina ; Del Turco, D. ; Layer, Paul G. (1996)
Proliferating and differentiating Schwann cell cultures from embryonic chick sciatic nerve maintained for months in vitro without antimitotics or growth factors.
In: European journal of cell biology 70, 70 (2)
Artikel, Bibliographie

Layer, Paul G. ; Ebert, C. ; Treskatis, S. ; Weikert, T. ; Willbold, Elmar
Hrsg.: Quinn, D. M. (1995)
Glycosylated inactive forms of chicken butyrylcholinesterases and their possible functions.
In: Enzymes of the cholinesterase family
Buchkapitel, Bibliographie

Willbold, Elmar ; Reinicke, Michael ; Lance-Jones, Cynthia ; Lagenaur, Carl ; Lemmon, Vance ; Layer, Paul G. (1995)
Müller glia stabilizes cell columns during retinal development: lateral migration but not neuropil growth is inhibited in mixed chick-quail retinospheroids.
In: European journal of neuroscience, 7
Artikel, Bibliographie

Layer, Paul G. (1995)
Nonclassical roles of cholinesterases in the embryonic brain and possible links to Alzheimer disease.
In: Alzheimer disease and associated disorders, 9 (Suppl. 2)
Artikel, Bibliographie

Layer, Paul G. ; Willbold, Elmar (1995)
Novel functions of cholinesterases in development, physiology and disease.
In: Progress in histochemistry and cytochemistry, 29 (3)
Artikel, Bibliographie

Willbold, E. ; Layer, Paul G. (1994)
Butyrylcholinesterase regulates laminar retinogenesis of the chick embryo in vitro.
In: European journal of cell biology, 64 (1)
Artikel, Bibliographie

Alber, R. ; Sporns, O. ; Weikert, T. ; Willbold, E. ; Layer, Paul G. (1994)
Cholinesterases and peanut agglutinin binding related to cell proliferation and axonal growth in embryonic chick limbs.
In: Anatomy and embryology, 190 (5)
Artikel, Bibliographie

Layer, Paul G. ; Willbold, E. (1994)
Cholinesterases in avian neurogenesis.
In: International review of cytology, 151
Artikel, Bibliographie

Weikert, T. ; Ebert, C. ; Rasched, I. ; Layer, Paul G. (1994)
Novel inactive and distinctively glycosylated forms of butyrylcholinesterase from chicken serum.
In: Journal of neurochemistry, 63 (1)
Artikel, Bibliographie

Weikert, T. ; Rathjen, F. G. ; Layer, Paul G. (1994)
Use of ELISA to G4 antigen to quantitate neurite outgrowth in the chick both in vivo and in vitro.
In: Journal of neurochemistry, 62 (4)
Artikel, Bibliographie

Weikert, T. ; Layer, Paul G. (1994)
The carbohydrate epitope HNK-1 is present on all inactive, but not on all active forms of chicken butyrylcholinesterase.
In: Neuroscience letters, 176 (1)
Artikel, Bibliographie

Layer, Paul G. ; Weikert, T. ; Alber, R. (1993)
Cholinesterases regulate neurite growth of chick nerve cells in vitro by means of a non-enzymatic mechanism.
In: Cell and tissue research, 273 (2)
Artikel, Bibliographie

Layer, Paul G. ; Willbold, E. (1993)
Histogenesis of the avian retina in reaggregation culture: from dissociated cells to laminar neuronal networks.
In: International review of cytology, 146
Artikel, Bibliographie

Treskatis, S. ; Ebert, C. ; Layer, Paul G. (1992)
Butyrylcholinesterase from chicken brain is smaller than that from serum: its purification, glycosylation, and membrane association.
In: Journal of neurochemistry, 58 (6)
Artikel, Bibliographie

Layer, Paul G. ; Weikert, T. ; Willbold, E. (1992)
Chicken retinospheroids as developmental and pharmacological in vitro models: acetylcholinesterase is regulated by its own and by butyrylcholinesterase activity.
In: Cell and tissue research, 268 (3)
Artikel, Bibliographie

Willbold, E. ; Layer, Paul G. (1992)
Formation of neuroblastic layers in chicken retinospheroids: the fibre layer of Chievitz secludes AChE-positive cells from mitotic cells.
In: Cell and tissue research, 268 (3)
Artikel, Bibliographie

Willbold, Elmar ; Layer, Paul G. (1992)
A Hidden Retinal Regenerative Capacity from the Chick Ciliary Margin is Reactivated In Vitro, that is Accompanied by Down-regulation of Butyrylcholinesterase.
In: The European journal of neuroscience, 4 (3)
Artikel, Bibliographie

Layer, Paul G. (1991)
Cholinesterases during development of the avian nervous system.
In: Cellular and molecular neurobiology, 11 (1)
Artikel, Bibliographie

Layer, Paul G. ; Kaulich, S. (1991)
Cranial nerve growth in birds is preceded by cholinesterase expression during neural crest cell migration and the formation of an HNK-1 scaffold.
In: Cell and tissue research, 265 (3)
Artikel, Bibliographie

Wolburg, H. ; Willbold, E. ; Layer, Paul G. (1991)
Müller glia endfeet, a basal lamina and the polarity of retinal layers form properly in vitro only in the presence of marginal pigmented epithelium.
In: Cell and tissue research, 264 (3)
Artikel, Bibliographie

Layer, Paul G. (1990)
Cholinesterases preceding major tracts in vertebrate neurogenesis.
In: BioEssays : news and reviews in molecular, cellular and developmental biology, 12 (9)
Artikel, Bibliographie

Layer, Paul G. (1990)
Cholinesterases reveal early patterns of neurogenesis in the chick.
In: Acta histochemica. Supplementband, 38
Artikel, Bibliographie

Weikert, T. ; Rathjen, F. G. ; Layer, Paul G. (1990)
Developmental maps of acetylcholinesterase and G4-antigen of the early chicken brain: long-distance tracts originate from AChE-producing cell bodies.
In: Journal of neurobiology, 21 (3)
Artikel, Bibliographie

Liu, L. ; Jiang, L. Z. ; Layer, Paul G. (1990)
[Effect of pigmented epithelium from different developmental stages of chick embryo on cell growth of retinal explants].
In: Shi yan sheng wu xue bao, 23 (1)
Artikel, Bibliographie

Layer, Paul G. ; Alber, R. (1990)
Patterning of chick brain vesicles as revealed by peanut agglutinin and cholinesterases.
In: Development (Cambridge, England), 109 (3)
Artikel, Bibliographie

Layer, Paul G. ; Alber, R. ; Mansky, P. ; Vollmer, G. ; Willbold, E. (1990)
Regeneration of a chimeric retina from single cells in vitro: cell-lineage-dependent formation of radial cell columns by segregated chick and quail cells.
In: Cell and tissue research, 259 (2)
Artikel, Bibliographie

Layer, Paul G. ; Makovitzky, J. (1990)
The laminar development of the embryonic chicken retina in vitro as detected by "topo-optical reactions".
In: Acta histochemica. Supplementband, 40
Artikel, Bibliographie

Layer, Paul G. ; Willbold, E. (1989)
Embryonic chicken retinal cells can regenerate all cell layers in vitro, but ciliary pigmented cells induce their correct polarity.
In: Cell and tissue research, 258 (2)
Artikel, Bibliographie

Layer, Paul G. ; Rommel, S. ; Bülthoff, H. ; Hengstenberg, R. (1988)
Independent spatial waves of biochemical differentiation along the surface of chicken brain as revealed by the sequential expression of acetylcholinesterase.
In: Cell and tissue research, 251 (3)
Artikel, Bibliographie

Liu, L. ; Cheng, S. H. ; Jiang, L. Z. ; Hansmann, G. ; Layer, Paul G. (1988)
The pigmented epithelium sustains cell growth and tissue differentiation of chicken retinal explants in vitro.
In: Experimental eye research, 46 (5)
Artikel, Bibliographie

Vollmer, G. ; Layer, Paul G. (1987)
Cholinesterases and cell proliferation in "nonstratified" and "stratified" cell aggregates from chicken retina and tectum.
In: Cell and tissue research, 250 (3)
Artikel, Bibliographie

Layer, Paul G. ; Alber, R. ; Sporns, O. (1987)
Quantitative development and molecular forms of acetyl- and butyrylcholinesterase during morphogenesis and synaptogenesis of chick brain and retina.
In: Journal of neurochemistry, 49 (1)
Artikel, Bibliographie

Layer, Paul G. ; Sporns, O. (1987)
Spatiotemporal relationship of embryonic cholinesterases with cell proliferation in chicken brain and eye.
In: Proceedings of the National Academy of Sciences of the United States of America, 84 (1)
Artikel, Bibliographie

Liu, L. ; Halfter, W. ; Layer, Paul G. (1986)
Inhibition of cell proliferation by cytosine-arabinoside and its interference with spatial and temporal differentiation patterns in the chick retina.
In: Cell and tissue research, 244 (3)
Artikel, Bibliographie

Vollmer, G. ; Layer, Paul G. (1986)
Lucifer Yellow stains a subpopulation of chicken retinoblasts preferentially 3 h after their last round of DNA synthesis.
In: Brain research, 392 (1-2)
Artikel, Bibliographie

Vollmer, G. ; Layer, Paul G. (1986)
Reaggregation of chick retinal and mixtures of retinal and pigment epithelial cells: the degree of laminar organization is dependent on age.
In: Neuroscience letters, 63 (1)
Artikel, Bibliographie

Vollmer, G. ; Layer, Paul G. (1986)
An in vitro model of proliferation and differentiation of the chick retina: coaggregates of retinal and pigment epithelial cells.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 6 (7)
Artikel, Bibliographie

Vollmer, G. ; Layer, Paul G. ; Gierer, A. (1984)
Reaggregation of embryonic chick retina cells: pigment epithelial cells induce a high order of stratification.
In: Neuroscience letters, 48 (2)
Artikel, Bibliographie

Liu, L. ; Layer, Paul G. (1984)
Spatio-temporal patterns of differentiation of whole heads of the embryonic chick as revealed by binding of a FITC-coupled peanut-agglutinin (FITC-PNA).
In: Brain research, 314 (2)
Artikel, Bibliographie

Layer, Paul G. ; Kotz, S. (1983)
Asymmetrical developmental pattern of uptake of Lucifer Yellow into amacrine cells in the embryonic chick retina.
In: Neuroscience, 9 (4)
Artikel, Bibliographie

Layer, Paul G. ; Shooter, E. M. (1983)
Binding and degradation of nerve growth factor by PC12 pheochromocytoma cells.
In: The Journal of biological chemistry, 258 (5)
Artikel, Bibliographie

Liu, L. ; Layer, Paul G. ; Gierer, A. (1983)
Binding of FITC-coupled peanut-agglutinin (FITC-PNA) to embryonic chicken retinas reveals developmental spatio-temporal patterns.
In: Brain research, 284 (2-3)
Artikel, Bibliographie

Layer, Paul G. (1983)
Comparative localization of acetylcholinesterase and pseudocholinesterase during morphogenesis of the chicken brain.
In: Proceedings of the National Academy of Sciences of the United States of America, 80 (20)
Artikel, Bibliographie

Layer, Paul G. ; Vollmer, G. ; Kotz, S. (1983)
Selective uptake of Lucifer Yellow into different cell populations of the developing chicken retina.
In: Neuroscience letters, 35 (3)
Artikel, Bibliographie

Layer, Paul G. ; Vollmer, G. (1982)
Lucifer yellow stains displaced amacrine cells of the chicken retina during embryonic development.
In: Neuroscience letters, 31 (2)
Artikel, Bibliographie

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