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Einträge mit Organisationseinheit "10 Fachbereich Biologie > Systems Biology of the Stress Response"

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Anzahl der Einträge auf dieser Ebene: 27.

B

Borcherds, Wade ; Theillet, François-Xavier ; Katzer, Andrea ; Finzel, Ana ; Mishall, Katie M. ; Powell, Anne T. ; Wu, Hongwei ; Manieri, Wanda ; Dieterich, Christoph ; Selenko, Philipp ; Loewer, Alexander ; Daughdrill, Gary W. :
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
In: Nature chemical biology, 10 (12) pp. 1000-2. ISSN 1552-4469
[Artikel], (2014)

Batchelor, Eric ; Loewer, Alexander ; Mock, Caroline ; Lahav, Galit :
Stimulus-dependent dynamics of p53 in single cells.
In: Molecular systems biology, 7 p. 488. ISSN 1744-4292
[Artikel], (2011)

Batchelor, Eric ; Loewer, Alexander ; Lahav, Galit :
The ups and downs of p53: understanding protein dynamics in single cells.
In: Nature reviews. Cancer, 9 (5) pp. 371-7. ISSN 1474-1768
[Artikel], (2009)

Batchelor, Eric ; Mock, Caroline S. ; Bhan, Irun ; Loewer, Alexander ; Lahav, Galit :
Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
In: Molecular cell, 30 (3) pp. 277-89. ISSN 1097-4164
[Artikel], (2008)

F

Finzel, Ana ; Grybowski, Andrea ; Strasen, Jette ; Cristiano, Elena ; Loewer, Alexander :
Hyper-activation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.
In: Molecular biology of the cell, 27 (15) pp. 2360-2367. ISSN 1939-4586
[Artikel], (2016)

G

González, Erik ; Rother, Marion ; Kerr, Markus C. ; Al-Zeer, Munir A. ; Abu-Lubad, Mohammad ; Kessler, Mirjana ; Brinkmann, Volker ; Loewer, Alexander ; Meyer, Thomas F. :
Chlamydia infection depends on a functional MDM2-p53 axis.
In: Nature communications, 5 p. 5201. ISSN 2041-1723
[Artikel], (2014)

K

Karanam, Ketki ; Loewer, Alexander ; Lahav, Galit :
Dynamics of the DNA damage response: insights from live-cell imaging.
In: Briefings in functional genomics, 12 (2) pp. 109-17. ISSN 2041-2657
[Artikel], (2013)

Karanam, Ketki ; Kafri, Ran ; Loewer, Alexander ; Lahav, Galit :
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.
In: Molecular cell, 47 (2) pp. 320-9. ISSN 1097-4164
[Artikel], (2012)

L

Loewer, Alexander ; Karanam, Ketki ; Mock, Caroline ; Lahav, Galit :
The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.
In: BMC biology, 11 p. 114. ISSN 1741-7007
[Artikel], (2013)

Loewer, Alexander ; Lahav, Galit :
We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells.
In: Current opinion in genetics & development, 21 (6) pp. 753-8. ISSN 1879-0380
[Artikel], (2011)

Loewer, Alexander ; Batchelor, Eric ; Gaglia, Giorgio ; Lahav, Galit :
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.
In: Cell, 142 (1) pp. 89-100. ISSN 1097-4172
[Artikel], (2010)

Loewer, Alexander ; Lahav, Galit :
Cellular conference call: external feedback affects cell-fate decisions.
In: Cell, 124 (6) pp. 1128-30. ISSN 0092-8674
[Artikel], (2006)

Loewer, Alexander ; Soba, Peter ; Beyreuther, Konrad ; Paro, Renato ; Merdes, Gunter :
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development.
In: EMBO reports, 5 (4) pp. 405-11. ISSN 1469-221X
[Artikel], (2004)

M

Mönke, Gregor ; Cristiano, Elena ; Finzel, Ana ; Friedrich, Dhana ; Herzel, Hanspeter ; Falcke, Martin ; Loewer, Alexander :
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
In: Scientific reports, 7 p. 46571. ISSN 2045-2322
[Artikel], (2017)

Memczak, Sebastian ; Jens, Marvin ; Elefsinioti, Antigoni ; Torti, Francesca ; Krueger, Janna ; Rybak, Agnieszka ; Maier, Luisa ; Mackowiak, Sebastian D. ; Gregersen, Lea H. ; Munschauer, Mathias ; Loewer, Alexander ; Ziebold, Ulrike ; Landthaler, Markus ; Kocks, Christine ; le Noble, Ferdinand ; Rajewsky, Nikolaus :
Circular RNAs are a large class of animal RNAs with regulatory potency.
In: Nature, 495 (7441) pp. 333-8. ISSN 1476-4687
[Artikel], (2013)

Merdes, Gunter ; Soba, Peter ; Loewer, Alexander ; Bilic, Michaela V. ; Beyreuther, Konrad ; Paro, Renato :
Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila.
In: The EMBO journal, 23 (20) pp. 4082-95. ISSN 0261-4189
[Artikel], (2004)

O

Orth, James D. ; Loewer, Alexander ; Lahav, Galit ; Mitchison, Timothy J. :
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.
In: Molecular biology of the cell, 23 (4) pp. 567-76. ISSN 1939-4586
[Artikel], (2012)

P

Paek, Andrew L. ; Liu, Julia C. ; Loewer, Alexander ; Forrester, William C. ; Lahav, Galit :
Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing.
In: Cell, 165 (3) pp. 631-42. ISSN 1097-4172
[Artikel], (2016)

Purvis, Jeremy E. ; Karhohs, Kyle W. ; Mock, Caroline ; Batchelor, Eric ; Loewer, Alexander ; Lahav, Galit :
p53 dynamics control cell fate.
In: Science (New York, N.Y.), 336 (6087) pp. 1440-4. ISSN 1095-9203
[Artikel], (2012)

Peshkin, L. ; Goni, J. ; Loewer, Alexander ; Kolluri, R. S. ; Lahav, Galit ; Wall, D. :
Morphology from texture in cytometry.
In: IJTS, 16 (s10) pp. 41-55.
[Artikel], (2009)

R

Rusu, Patricia ; Jansen, Anna ; Soba, Peter ; Kirsch, Joachim ; Loewer, Alexander ; Merdes, Gunter ; Kuan, Yung-Hui ; Jung, Anita ; Beyreuther, Konrad ; Kjaerulff, Ole ; Kins, Stefan :
Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity.
In: The European journal of neuroscience, 25 (4) pp. 1079-86. ISSN 0953-816X
[Artikel], (2007)

S

Schrenk-Siemens, Katrin ; Wende, Hagen ; Prato, Vincenzo ; Song, Kun ; Rostock, Charlotte ; Loewer, Alexander ; Utikal, Jochen ; Lewin, Gary R. ; Lechner, Stefan G. ; Siemens, Jan :
PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors.
In: Nature neuroscience, 18 (1) pp. 10-6. ISSN 1546-1726
[Artikel], (2015)

Schueler, Markus ; Munschauer, Mathias ; Gregersen, Lea Haarup ; Finzel, Ana ; Loewer, Alexander ; Chen, Wei ; Landthaler, Markus ; Dieterich, Christoph :
Differential protein occupancy profiling of the mRNA transcriptome.
In: Genome biology, 15 (1) R15. ISSN 1474-760X
[Artikel], (2014)

Stempfle, Denise ; Kanwar, Ritu ; Loewer, Alexander ; Fortini, Mark E. ; Merdes, Gunter :
In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.
In: Molecular and cellular biology, 30 (13) pp. 3165-75. ISSN 1098-5549
[Artikel], (2010)

Soba, Peter ; Eggert, Simone ; Wagner, Katja ; Zentgraf, Hanswalter ; Siehl, Katjuscha ; Kreger, Sylvia ; Loewer, Alexander ; Langer, Andreas ; Merdes, Gunter ; Paro, Renato ; Masters, Colin L. ; Müller, Ulrike ; Kins, Stefan ; Beyreuther, Konrad :
Cell interactions are promoted by transdimerization of APP family members, arranged as homo- or heterocomplexes in synaptic membranes.
In: The EMBO journal, 25 (3) p. 653. ISSN 0261-4189
[Artikel], (2006)

T

Toettcher, Jared E. ; Mock, Caroline ; Batchelor, Eric ; Loewer, Alexander ; Lahav, Galit :
A synthetic-natural hybrid oscillator in human cells.
In: Proceedings of the National Academy of Sciences of the United States of America, 107 (39) pp. 17047-52. ISSN 1091-6490
[Artikel], (2010)

Toettcher, Jared E. ; Loewer, Alexander ; Ostheimer, Gerard J. ; Yaffe, Michael B. ; Tidor, Bruce ; Lahav, Galit :
Distinct mechanisms act in concert to mediate cell cycle arrest.
In: Proceedings of the National Academy of Sciences of the United States of America, 106 (3) pp. 785-90. ISSN 1091-6490
[Artikel], (2009)

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