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Friedrich, Dhana ; Friedel, Laura ; Finzel, Ana ; Herrmann, Andreas ; Preibisch, Stephan ; Loewer, Alexander (2019)
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
In: Molecular systems biology, 15 (12)
doi: 10.15252/msb.20199068
Artikel, Bibliographie
Mönke, Gregor ; Cristiano, Elena ; Finzel, Ana ; Friedrich, Dhana ; Herzel, Hanspeter ; Falcke, Martin ; Loewer, Alexander (2017)
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
In: Scientific Reports, 7
doi: 10.1038/srep46571
Artikel, Bibliographie
Finzel, Ana ; Grybowski, Andrea ; Strasen, Jette ; Cristiano, Elena ; Loewer, Alexander (2016)
Hyper-activation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.
In: Molecular biology of the cell, 27 (15)
Artikel, Bibliographie
Borcherds, Wade ; Theillet, François-Xavier ; Katzer, Andrea ; Finzel, Ana ; Mishall, Katie M. ; Powell, Anne T. ; Wu, Hongwei ; Manieri, Wanda ; Dieterich, Christoph ; Selenko, Philipp ; Loewer, Alexander ; Daughdrill, Gary W. (2014)
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
In: Nature chemical biology, 10 (12)
Artikel, Bibliographie
Schueler, Markus ; Munschauer, Mathias ; Gregersen, Lea Haarup ; Finzel, Ana ; Loewer, Alexander ; Chen, Wei ; Landthaler, Markus ; Dieterich, Christoph (2014)
Differential protein occupancy profiling of the mRNA transcriptome.
In: Genome biology, 15 (1)
Artikel, Bibliographie