Philippe, Grégoire Jean-Baptiste ; Huang, Yen-Hua ; Mittermeier, Anna ; Brown, Christopher J. ; Kaas, Quentin ; Ramlan, Siti Radhiah ; Wang, Conan K. ; Lane, David ; Loewer, Alexander ; Troeira Henriques, Sónia ; Craik, David J. (2024)
Delivery to, and reactivation of, the p53 Pathway in cancer cells using a grafted cyclotide conjugated with a cell-penetrating peptide.
In: Journal of medicinal chemistry, 67 (2)
doi: 10.1021/acs.jmedchem.3c01682
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Philippe, Grégoire J.-B. ; Mittermeier, Anna ; Lawrence, Nicole ; Huang, Yen-Hua ; Condon, Nicholas D. ; Loewer, Alexander ; Craik, David J. ; Henriques, Sónia T. (2021)
Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells.
In: ACS chemical biology, 16 (2)
doi: 10.1021/acschembio.0c00988
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Philippe, Grégoire J.-B. ; Gaspar, Diana ; Sheng, Caibin ; Huang, Yen-Hua ; Benfield, Aurélie H. ; Condon, Nicholas D. ; Weidmann, Joachim ; Lawrence, Nicole ; Loewer, Alexander ; Castanho, Miguel A. R. B. ; Craik, David J. ; Troeira Henriques, Sónia (2019)
Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix–Loop–Helix Peptides with Cell Penetrating and Tumor Suppressor Properties.
In: ACS Chemical Biology, 14 (9)
doi: 10.1021/acschembio.9b00593
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