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Cellular conference call: external feedback affects cell-fate decisions.

Loewer, Alexander and Lahav, Galit (2006):
Cellular conference call: external feedback affects cell-fate decisions.
In: Cell, 124 (6), pp. 1128-30. ISSN 0092-8674,
[Article]

Abstract

Cells often need to respond to multiple opposing signals simultaneously. In this issue of Cell, it is shown that challenging cells with multiple extracellular signals induces an external feedback that involves the release of and response to additional secreted factors with antagonistic functions. These results suggest that an individual cell's decision to die or survive is not wholly independent but depends, at least in part, on feedback from its neighbors.

Item Type: Article
Erschienen: 2006
Creators: Loewer, Alexander and Lahav, Galit
Title: Cellular conference call: external feedback affects cell-fate decisions.
Language: English
Abstract:

Cells often need to respond to multiple opposing signals simultaneously. In this issue of Cell, it is shown that challenging cells with multiple extracellular signals induces an external feedback that involves the release of and response to additional secreted factors with antagonistic functions. These results suggest that an individual cell's decision to die or survive is not wholly independent but depends, at least in part, on feedback from its neighbors.

Journal or Publication Title: Cell
Journal volume: 124
Number: 6
Divisions: 10 Department of Biology
10 Department of Biology > Systems Biology of the Stress Response
Date Deposited: 02 Sep 2015 09:00
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