TU Darmstadt / ULB / TUbiblio

Einträge mit Organisationseinheit "10 Fachbereich Biologie > Neurophysiologie und neurosensorische Systeme"

Exportieren als [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Gruppiere nach: Autor(en) | Publikationsjahr | Typ des Eintrags | Sprache | Keine Gruppierung
Es werden nur Einträge angezeigt, bei denen keine untergeordnete Organisationseinheit ausgewählt wurde. Anzahl: 117.

Artikel

Bernhard, Max ; Laube, Bodo (2022)
Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs.
In: Scientific Reports, 2022, 10
doi: 10.26083/tuprints-00021126
Artikel, Zweitveröffentlichung, Verlagsversion

Langer, Kai ; Müller-Längle, Adriana ; Wempe, Jannik ; Laube, Bodo (2022)
Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.
In: Frontiers in Pharmacology, 2022, 12
doi: 10.26083/tuprints-00020785
Artikel, Zweitveröffentlichung, Verlagsversion

Kleineidam, Luca ; Wolfsgruber, Steffen ; Weyrauch, Anne-Sophie ; Zulka, Linn E. ; Forstmeier, Simon ; Roeske, Sandra ; Bussche, Hendrik van den ; Kaduszkiewicz, Hanna ; Wiese, Birgitt ; Weyerer, Siegfried ; Werle, Jochen ; Fuchs, Angela ; Pentzek, Michael ; Brettschneider, Christian ; König, Hans-Helmut ; Weeg, Dagmar ; Bickel, Horst ; Luppa, Melanie ; Rodriguez, Francisca S. ; Freiesleben, Silka Dawn ; Erdogan, Selin ; Unterfeld, Chantal ; Peters, Oliver ; Spruth, Eike J. ; Altenstein, Slawek ; Lohse, Andrea ; Priller, Josef ; Fliessbach, Klaus ; Kobeleva, Xenia ; Schneider, Anja ; Bartels, Claudia ; Schott, Björn H. ; Wiltfang, Jens ; Maier, Franziska ; Glanz, Wenzel ; Incesoy, Enise I. ; Butryn, Michaela ; Düzel, Emrah ; Buerger, Katharina ; Janowitz, Daniel ; Ewers, Michael ; Rauchmann, Boris-Stephan ; Perneczky, Robert ; Kilimann, Ingo ; Görß, Doreen ; Teipel, Stefan ; Laske, Christoph ; Munk, Matthias H. J. ; Spottke, Annika ; Roy, Nina ; Brosseron, Frederic ; Heneka, Michael T. ; Ramirez, Alfredo ; Yakupov, Renat ; Scherer, Martin ; Maier, Wolfgang ; Jessen, Frank ; Riedel-Heller, Steffi G. ; Wagner, Michael (2022)
Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.
In: Frontiers in Psychology, 13
doi: 10.3389/fpsyg.2022.957308
Artikel, Bibliographie

Langer, Kai ; Müller-Längle, Adriana ; Wempe, Jannik ; Laube, Bodo (2021)
Analysis of M4 Transmembrane Segments in NMDA Receptor Function : A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.
In: Frontiers in pharmacology, 12
doi: 10.3389/fphar.2021.769046
Artikel, Bibliographie

Bernhard, Max ; Laube, Bodo (2020)
Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs.
In: Scientific reports, 10 (1)
doi: 10.1038/s41598-020-73157-2
Artikel, Bibliographie

Bernhard, Max ; Diefenbach, Mathias ; Biesalski, Markus ; Laube, Bodo (2020)
Electrical Sensing of Phosphonates by Functional Coupling of Phosphonate Binding Protein PhnD to Solid-State Nanopores.
In: ACS sensors, 5 (1)
doi: 10.1021/acssensors.9b02097
Artikel, Bibliographie

Müller-Längle, Adriana ; Lutz, Henrik ; Hehlgans, Stephanie ; Rödel, Franz ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells-A Potential Target for Adjuvant Radiotherapy.
In: Cancers, 11 (4)
doi: 10.3390/cancers11040503
Artikel, Bibliographie

Lutz, Henrik ; Nguyen, Thy ; Joswig, Juliane ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor Signaling Mediates cFos Expression via Top2β-Induced DSBs in Glioblastoma Cells.
In: Cancers, 2019, 11 (3)
doi: 10.3390/cancers11030306
Artikel, Zweitveröffentlichung

Schönrock, Michael ; Thiel, Gerhard ; Laube, Bodo (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.
In: Communications biology, 2
doi: 10.1038/s42003-019-0320-y
Artikel, Bibliographie

Bledsoe, Douglas ; Vacca, Bryanna ; Laube, Bodo ; Klein, Bradley G. ; Costa, Blaise (2019)
Ligand binding domain interface: A tipping point for pharmacological agents binding with GluN1/2A subunit containing NMDA receptors.
In: European journal of pharmacology, 844
doi: 10.1016/j.ejphar.2018.12.023
Artikel, Bibliographie

Schönrock, Michael ; Thiel, Gerhard ; Laube, Bodo (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.
In: Communications Biology, 2019, 2 (1)
doi: 10.1038/s42003-019-0320-y
Artikel, Zweitveröffentlichung

Müller-Längle, Adriana ; Lutz, Henrik ; Hehlgans, Stephanie ; Rödel, Franz ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells — A Potential Target for Adjuvant Radiotherapy.
In: Cancers, 2019, 11 (4)
doi: 10.3390/cancers11040503
Artikel, Zweitveröffentlichung

Richter, Max C. ; Ludewig, Susann ; Winschel, Alex ; Abel, Tobias ; Bold, Charlotte ; Salzburger, Leonie R. ; Klein, Susanne ; Han, Kang ; Weyer, Sascha W. ; Fritz, Ann-Kristina ; Laube, Bodo ; Wolfer, David P. ; Buchholz, Christian J. ; Korte, Martin ; Müller, Ulrike C. (2018)
Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.
In: The EMBO journal, 37 (11)
doi: 10.15252/embj.201798335
Artikel, Bibliographie

Platzer, Konrad ; Yuan, Hongjie ; Schütz, Hannah ; Winschel, Alexander ; Chen, Wenjuan ; Hu, Chun ; Kusumoto, Hirofumi ; Heyne, Henrike O. ; Helbig, Katherine L. ; Tang, Sha ; Willing, Marcia C. ; Tinkle, Brad T. ; Adams, Darius J. ; Depienne, Christel ; Keren, Boris ; Mignot, Cyril ; Frengen, Eirik ; Strømme, Petter ; Biskup, Saskia ; Döcker, Dennis ; Strom, Tim M. ; Mefford, Heather C. ; Myers, Candace T. ; Muir, Alison M. ; LaCroix, Amy ; Sadleir, Lynette ; Scheffer, Ingrid E. ; Brilstra, Eva ; Haelst, Mieke M. van ; Smagt, Jasper J. van der ; Bok, Levinus A. ; Møller, Rikke S. ; Jensen, Uffe B. ; Millichap, John J. ; Berg, Anne T. ; Goldberg, Ethan M. ; De Bie, Isabelle ; Fox, Stephanie ; Major, Philippe ; Jones, Julie R. ; Zackai, Elaine H. ; Abou Jamra, Rami ; Rolfs, Arndt ; Leventer, Richard J. ; Lawson, John A. ; Roscioli, Tony ; Jansen, Floor E. ; Ranza, Emmanuelle ; Korff, Christian M. ; Lehesjoki, Anna-Elina ; Courage, Carolina ; Linnankivi, Tarja ; Smith, Douglas R. ; Stanley, Christine ; Mintz, Mark ; McKnight, Dianalee ; Decker, Amy ; Tan, Wen-Hann ; Tarnopolsky, Mark A. ; Brady, Lauren I. ; Wolff, Markus ; Dondit, Lutz ; Pedro, Helio F. ; Parisotto, Sarah E. ; Jones, Kelly L. ; Patel, Anup D. ; Franz, David N. ; Vanzo, Rena ; Marco, Elysa ; Ranells, Judith D. ; Di Donato, Nataliya ; Dobyns, William B. ; Laube, Bodo ; Traynelis, Stephen F. ; Lemke, Johannes R. (2017)
GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects.
In: Journal of medical genetics, 54 (7)
Artikel, Bibliographie

Schoenrock, Michael ; Poci, Alina ; Thiel, Gerhard ; Laube, Bodo (2017)
Design of a Glutamate-Activated Potassium Channel upon Fusion of the Ligand-Binding Domain of the Mammalian AMPA Receptor Glua1 to the Channel Pore of the Viral ATCV-1 KCV K+ Channel.
In: Biophysical journal, 112 (3)
Artikel, Bibliographie

Bernhard, Max ; Laube, Bodo (2017)
Functional Coupling of Bacterial Binding Protein with the Channel Pore of an Ionotropic Glutamate Receptor.
In: Biophysical journal, 112 (3)
Artikel, Bibliographie

Bledsoe, Douglas ; Tamer, Ceyhun ; Mesic, Ivana ; Madry, Christian ; Klein, Bradley G. ; Laube, Bodo ; Costa, Blaise M. (2017)
Positive modulatory interactions of NMDA receptor GluN1/2B ligand binding domains attenuate antagonists activity.
In: Frontiers in Pharmacology, 8
doi: 10.3389/fphar.2017.00229
Artikel, Bibliographie

Mesic, Ivana ; Madry, Christian ; Geider, Kirsten ; Bernhard, Max ; Betz, Heinrich ; Laube, Bodo (2016)
The N-terminal domain of the GluN3A subunit determines the efficacy of glycine-activated NMDA receptors.
In: Neuropharmacology, 105
Artikel, Bibliographie

Lemke, Johannes R. ; Geider, Kirsten ; Helbig, Katherine L. ; Heyne, Henrike O. ; Schütz, Hannah ; Hentschel, Julia ; Courage, Carolina ; Depienne, Christel ; Nava, Caroline ; Heron, Delphine ; Møller, Rikke S. ; Hjalgrim, Helle ; Lal, Dennis ; Neubauer, Bernd A. ; Nürnberg, Peter ; Thiele, Holger ; Kurlemann, Gerhard ; Arnold, Georgianne L. ; Bhambhani, Vikas ; Bartholdi, Deborah ; Pedurupillay, Christeen Ramane J. ; Misceo, Doriana ; Frengen, Eirik ; Strømme, Petter ; Dlugos, Dennis J. ; Doherty, Emily S. ; Bijlsma, Emilia K. ; Ruivenkamp, Claudia A. ; Hoffer, Mariette J. V. ; Goldstein, Amy ; Rajan, Deepa S. ; Narayanan, Vinodh ; Ramsey, Keri ; Belnap, Newell ; Schrauwen, Isabelle ; Richholt, Ryan ; Koeleman, Bobby P. C. ; Sá, Joaquim ; Mendonça, Carla ; Kovel, Carolien de ; Weckhuysen, Sarah ; Hardies, Katia ; De Jonghe, Peter ; De Meirleir, Linda ; Milh, Mathieu ; Badens, Catherine ; Lebrun, Marine ; Busa, Tiffany ; Francannet, Christine ; Piton, Amélie ; Riesch, Erik ; Biskup, Saskia ; Vogt, Heinrich ; Dorn, Thomas ; Helbig, Ingo ; Michaud, Jacques L. ; Laube, Bodo ; Syrbe, Steffen (2016)
Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy.
In: Neurology, 86 (23)
Artikel, Bibliographie

Lynagh, Timothy ; Beech, Robin N. ; Lalande, Maryline J. ; Keller, Kevin ; Cromer, Brett A. ; Wolstenholme, Adrian J. ; Laube, Bodo (2015)
Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels.
In: Scientific reports, 24 (5)
Artikel, Bibliographie

Lynagh, Timothy ; Laube, Bodo (2014)
Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 (6)
Artikel, Bibliographie

Lemke, Johannes R. ; Hendrickx, Rik ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Harvey, Robert J. ; James, Victoria M. ; Pepler, Alex ; Steiner, Isabelle ; Hörtnagel, Konstanze ; Neidhardt, John ; Ruf, Susanne ; Wolff, Markus ; Bartholdi, Deborah ; Caraballo, Roberto ; Platzer, Konrad ; Suls, Arvid ; De Jonghe, Peter ; Biskup, Saskia ; Weckhuysen, Sarah (2014)
GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.
In: Annals of neurology, 75 (1)
Artikel, Bibliographie

Lynagh, Timothy ; Cromer, Brett A. ; Dufour, Vanessa ; Laube, Bodo (2014)
Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics.
In: International journal for parasitology. Drugs and drug resistance, 4 (3)
Artikel, Bibliographie

Spiczak, Sarah von ; Lal, D. ; Reinthaler, E. M. ; Steiner, I. ; Nothnagel, M. ; Laube, Bodo ; Schwake, M. ; Hoffmann, P. ; Herms, S. ; Altmüller, J. ; Toliat, M. R. ; Thiele, H. ; Nürnberg, P. ; Wilhelm, C. ; Stephani, U. ; Helbig, I. ; Lerche, H. ; Zimprich, F. ; Neubauer, B. A. ; Biskup, S. ; Lemke, J. R. (2013)
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Epilepsia, 54
Artikel, Bibliographie

Lynagh, Timothy ; Kunz, Alexander ; Laube, Bodo (2013)
Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation.
In: ACS chemical neuroscience, 4 (11)
Artikel, Bibliographie

Lemke, Johannes R. ; Lal, Dennis ; Reinthaler, Eva M. ; Steiner, Isabelle ; Nothnagel, Michael ; Alber, Michael ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Finsterwalder, Katrin ; Franke, Andre ; Schilhabel, Markus ; Jähn, Johanna A. ; Muhle, Hiltrud ; Boor, Rainer ; Paesschen, Wim van ; Caraballo, Roberto ; Fejerman, Natalio ; Weckhuysen, Sarah ; De Jonghe, Peter ; Larsen, Jan ; Møller, Rikke S. ; Hjalgrim, Helle ; Addis, Laura ; Tang, Shan ; Hughes, Elaine ; Pal, Deb K. ; Veri, Kadi ; Vaher, Ulvi ; Talvik, Tiina ; Dimova, Petia ; Guerrero López, Rosa ; Serratosa, José M. ; Linnankivi, Tarja ; Lehesjoki, Anna-Elina ; Ruf, Susanne ; Wolff, Markus ; Buerki, Sarah ; Wohlrab, Gabriele ; Kroell, Judith ; Datta, Alexandre N. ; Fiedler, Barbara ; Kurlemann, Gerhard ; Kluger, Gerhard ; Hahn, Andreas ; Haberlandt, D. Edda ; Kutzer, Christina ; Sperner, Jürgen ; Becker, Felicitas ; Weber, Yvonne G. ; Feucht, Martha ; Steinböck, Hannelore ; Neophythou, Birgit ; Ronen, Gabriel M. ; Gruber-Sedlmayr, Ursula ; Geldner, Julia ; Harvey, Robert J. ; Hoffmann, Per ; Herms, Stefan ; Altmüller, Janine ; Toliat, Mohammad R. ; Thiele, Holger ; Nürnberg, Peter ; Wilhelm, Christian ; Stephani, Ulrich ; Helbig, Ingo ; Lerche, Holger ; Zimprich, Fritz ; Neubauer, Bernd A. ; Biskup, Saskia ; Spiczak, Sarah von (2013)
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Nature genetics, 45 (9)
Artikel, Bibliographie

Kallenborn-Gerhardt, Wiebke ; Lu, Ruirui ; Lorenz, Jana ; Gao, Wei ; Weiland, Jessica ; Del Turco, Domenico ; Deller, Thomas ; Laube, Bodo ; Betz, Heinrich ; Geisslinger, Gerd ; Schmidtko, Achim (2012)
Prolonged zymosan-induced inflammatory pain hypersensitivity in mice lacking glycine receptor alpha2.
In: Behavioural brain research, 226 (1)
Artikel, Bibliographie

Dutertre, Sébastien ; Drwal, Malgorzata ; Laube, Bodo ; Betz, Heinrich (2012)
Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist binding site.
In: Journal of neurochemistry, 122 (1)
Artikel, Bibliographie

Costa, Blaise Mathias ; Irvine, Mark W. ; Fang, Guangyu ; Eaves, Richard J. ; Mayo-Martin, Maria Belen ; Laube, Bodo ; Jane, David E. ; Monaghan, Daniel T. (2012)
Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid.
In: Neuropharmacology, 62 (4)
Artikel, Bibliographie

Pult, Frauke ; Fallah, Ghada ; Braam, Ursula ; Detro-Dassen, Silvia ; Niculescu, Cristina ; Laube, Bodo ; Schmalzing, Günther (2011)
Robust post-translocational N-glycosylation at the extreme C-terminus of membrane and secreted proteins in Xenopus laevis oocytes and HEK293 cells.
In: Glycobiology, 21 (9)
Artikel, Bibliographie

Endele, Sabine ; Rosenberger, Georg ; Geider, Kirsten ; Popp, Bernt ; Tamer, Ceyhun ; Stefanova, Irina ; Milh, Mathieu ; Kortüm, Fanny ; Fritsch, Angela ; Pientka, Friederike K. ; Hellenbroich, Yorck ; Kalscheuer, Vera M. ; Kohlhase, Jürgen ; Moog, Ute ; Rappold, Gudrun ; Rauch, Anita ; Ropers, Hans-Hilger ; Spiczak, Sarah von ; Tönnies, Holger ; Villeneuve, Nathalie ; Villard, Laurent ; Zabel, Bernhard ; Zenker, Martin ; Laube, Bodo ; Reis, André ; Wieczorek, Dagmar ; Maldergem, Lionel van ; Kutsche, Kerstin (2010)
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
In: Nature genetics, 42 (11)
Artikel, Bibliographie

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo (2010)
Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification.
In: Frontiers in molecular neuroscience, 3
Artikel, Bibliographie

Haeger, Svenja ; Kuzmin, Dmitry ; Detro-Dassen, Silvia ; Lang, Niklas ; Kilb, Michael ; Tsetlin, Victor ; Betz, Heinrich ; Laube, Bodo ; Schmalzing, Günther (2010)
An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors.
In: Nature structural & molecular biology, 17 (1)
Artikel, Bibliographie

Maksay, Gábor ; Laube, Bodo ; Schemm, Rudolf ; Grudzinska, Joanna ; Drwal, Malgorzata ; Betz, Heinrich (2009)
Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.
In: Journal of neurochemistry, 109 (6)
Artikel, Bibliographie

Schumann, Tanja ; Grudzinska, Joanna ; Kuzmin, Dmitry ; Betz, Heinrich ; Laube, Bodo (2009)
Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator.
In: Neuropharmacology, 56 (1)
Artikel, Bibliographie

Laube, Bodo ; Betz, Heinrich (2009)
Die duale Rolle des Neurotransmitters Glyzin im zentralen Nervensystem.
In: Jahrbuch 2009 der Max-Planck-Gesellschaft
Artikel, Bibliographie

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo (2008)
Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist.
In: Proceedings of the National Academy of Sciences of the United States of America, 105 (34)
Artikel, Bibliographie

Grudzinska, Joanna ; Schumann, Tanja ; Schemm, Rudolf ; Betz, Heinrich ; Laube, Bodo (2008)
Mutations within the agonist-binding site convert the homomeric alpha1 glycine receptor into a Zn2+-activated chloride channel.
In: Channels (Austin, Tex.), 2 (1)
Artikel, Bibliographie

Schüler, Thomas ; Mesic, Ivana ; Madry, Christian ; Bartholomäus, Ingo ; Laube, Bodo (2008)
Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.
In: The Journal of biological chemistry, 283 (1)
Artikel, Bibliographie

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo ; Nemes, Péter (2008)
Hyperekplexia mutation R271L of alpha1 glycine receptors potentiates allosteric interactions of nortropeines, propofol and glycine with [3H]strychnine binding.
In: Neurochemistry international, 52 (1-2)
Artikel, Bibliographie

Madry, Christian ; Mesic, Ivana ; Betz, Heinrich ; Laube, Bodo (2007)
The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.
In: Molecular pharmacology, 72 (6)
Artikel, Bibliographie

Papadopoulos, Theofilos ; Korte, Martin ; Eulenburg, Volker ; Kubota, Hisahiko ; Retiounskaia, Marina ; Harvey, Robert J. ; Harvey, Kirsten ; O'Sullivan, Gregory A. ; Laube, Bodo ; Hülsmann, Swen ; Geiger, Jörg R. P. ; Betz, Heinrich (2007)
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice.
In: The EMBO journal, 26 (17)
Artikel, Bibliographie

Madry, Christian ; Mesic, Ivana ; Bartholomäus, Ingo ; Nicke, Annette ; Betz, Heinrich ; Laube, Bodo (2007)
Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function.
In: Biochemical and biophysical research communications, 354 (1)
Artikel, Bibliographie

Maier, Wolfgang ; Schemm, Rudolf ; Grewer, Christof ; Laube, Bodo (2007)
Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.
In: The Journal of biological chemistry, 282 (3)
Artikel, Bibliographie

Laube, Bodo (2007)
Dr. Jekyll & Mr. Hyde - das janusköpfige Zink.
In: BIOforum, 30 (3)
Artikel, Bibliographie

Betz, Heinrich ; Laube, Bodo (2006)
Glycine receptors: recent insights into their structural organization and functional diversity.
In: Journal of neurochemistry, 97 (6)
Artikel, Bibliographie

Hirzel, Klaus ; Müller, Ulrike ; Latal, A.Tobias ; Hülsmann, Swen ; Grudzinska, Joanna ; Seeliger, Mathias W. ; Betz, Heinrich ; Laube, Bodo (2006)
Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission.
In: Neuron, 52 (4)
Artikel, Bibliographie

Kondratskaya, Elena L. ; Betz, Heinrich ; Krishtal, Oleg A. ; Laube, Bodo (2005)
The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors.
In: Neuropharmacology, 49 (6)
Artikel, Bibliographie

Grudzinska, Joanna ; Schemm, Rudolf ; Haeger, Svenja ; Nicke, Annette ; Schmalzing, Guenther ; Betz, Heinrich ; Laube, Bodo (2005)
The beta subunit determines the ligand binding properties of synaptic glycine receptors.
In: Neuron, 45 (5)
Artikel, Bibliographie

Maier, Wolfgang ; Corrie, John E. T. ; Papageorgiou, George ; Laube, Bodo ; Grewer, Christof (2005)
Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor.
In: Journal of neuroscience methods, 142 (1)
Artikel, Bibliographie

Laube, Bodo ; Schemm, Rudolf ; Betz, Heinrich (2004)
Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor.
In: Neuropharmacology, 47 (7)
Artikel, Bibliographie

O'Shea, Sean Michael ; Becker, Lore ; Weiher, Hans ; Betz, Heinrich ; Laube, Bodo (2004)
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 24 (9)
Artikel, Bibliographie

Gomeza, Jesús ; Ohno, Koji ; Hülsmann, Swen ; Armsen, Wencke ; Eulenburg, Volker ; Richter, Diethelm W. ; Laube, Bodo ; Betz, Heinrich (2003)
Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
In: Neuron, 40 (4)
Artikel, Bibliographie

Ortinau, Stefanie ; Laube, Bodo ; Zimmermann, Herbert (2003)
ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 (12)
Artikel, Bibliographie

Foucaud, Bernard ; Laube, Bodo ; Schemm, Rudolf ; Kreimeyer, Annett ; Goeldner, Maurice ; Betz, Heinrich (2003)
Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling.
In: The Journal of biological chemistry, 278 (26)
Artikel, Bibliographie

Sadtler, Sven ; Laube, Bodo ; Lashub, Alhassan ; Nicke, Annette ; Betz, Heinrich ; Schmalzing, Günther (2003)
A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit.
In: The Journal of biological chemistry, 278 (19)
Artikel, Bibliographie

Perret, P. ; Laube, Bodo ; Schemm, R. ; Betz, H. ; Goeldner, M. ; Foucaud, B. (2002)
Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites.
In: Journal of receptor and signal transduction research, 22 (1-4)
Artikel, Bibliographie

Laube, Bodo ; Maksay, Gábor ; Schemm, Rudolf ; Betz, Heinrich (2002)
Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?
In: Trends in pharmacological sciences, 23 (11)
Artikel, Bibliographie

Laube, Bodo (2002)
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
In: The European journal of neuroscience, 16 (6)
Artikel, Bibliographie

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo (2002)
Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics.
In: Biochemical pharmacology, 64 (2)
Artikel, Bibliographie

Maksay, G. ; Laube, Bodo ; Betz, H. (2001)
Subunit-specific modulation of glycine receptors by neurosteroids.
In: Neuropharmacology, 41 (3)
Artikel, Bibliographie

Büttner, C. ; Sadtler, S. ; Leyendecker, A. ; Laube, Bodo ; Griffon, N. ; Betz, H. ; Schmalzing, G. (2001)
Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors.
In: The Journal of biological chemistry, 276 (46)
Artikel, Bibliographie

Wittekindt, B. ; Malany, S. ; Schemm, R. ; Otvos, L. ; Maccecchini, M. L. ; Laube, Bodo ; Betz, H. (2001)
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition.
In: Neuropharmacology, 41 (6)
Artikel, Bibliographie

Laube, Bodo ; Kuhse, J. ; Betz, H. (2000)
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
In: The Journal of physiology, (2)
doi: 10.1111/j.1469-7793.2000.t01-1-00215.x
Artikel, Bibliographie

Harvey, R. J. ; Schmieden, V. ; Holst, A. von ; Laube, Bodo ; Rohrer, H. ; Betz, H. (2000)
Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge.
In: The European journal of neuroscience, 12 (3)
Artikel, Bibliographie

Wittekindt, B. ; Betz, H. ; Laube, Bodo (2000)
Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by a HIV-1 glycoprotein 120 derived peptide.
In: Neuroscience letters, 280 (2)
Artikel, Bibliographie

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. (1999)
Reactive affinity probes for the mapping of the glycine-binding site of the NMDA receptor NR1 subunit.
In: Journal of receptor and signal transduction research, 19 (1-4)
Artikel, Bibliographie

Maksay, G. ; Laube, Bodo ; Betz, H. (1999)
Selective blocking effects of tropisetron and atropine on recombinant glycine receptors.
In: Journal of neurochemistry, 73 (2)
Artikel, Bibliographie

Laube, Bodo ; Betz, H. (1999)
Purification and heterologous expression of inhibitory glycine receptors.
In: Methods in enzymology, 294
Artikel, Bibliographie

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. (1999)
Evaluation and biological properties of reactive ligands for the mapping of the glycine site on the N-methyl-D-aspartate (NMDA) receptor.
In: Journal of medicinal chemistry, 42 (21)
Artikel, Bibliographie

Betz, H. ; Kuhse, J. ; Schmieden, V. ; Laube, Bodo ; Kirsch, J. ; Harvey, R. J. (1999)
Structure and functions of inhibitory and excitatory glycine receptors.
In: Annals of the New York Academy of Sciences, 868
Artikel, Bibliographie

Kins, S. ; Kuhse, J. ; Laube, Bodo ; Betz, H. ; Kirsch, J. (1999)
Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK 293 cells.
In: The European journal of neuroscience, 11 (2)
Artikel, Bibliographie

Kneussel, M. ; Brandstätter, J. H. ; Laube, Bodo ; Stahl, S. ; Müller, U. ; Betz, H. (1999)
Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 19 (21)
Artikel, Bibliographie

Honer, M. ; Benke, D. ; Laube, Bodo ; Kuhse, J. ; Heckendorn, R. ; Allgeier, H. ; Angst, C. ; Monyer, H. ; Seeburg, P. H. ; Betz, H. ; Möhler, H. (1998)
Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors.
In: The Journal of biological chemistry, 273 (18)
Artikel, Bibliographie

Ivanovic, A. ; Reiländer, H. ; Laube, Bodo ; Kuhse, J. (1998)
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
In: The Journal of biological chemistry, 273 (32)
Artikel, Bibliographie

Nikolic, Z. ; Laube, Bodo ; Weber, R. G. ; Lichter, P. ; Kioschis, P. ; Poustka, A. ; Mülhardt, C. ; Becker, C. M. (1998)
The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts.
In: The Journal of biological chemistry, 273 (31)
Artikel, Bibliographie

Laube, Bodo ; Kuhse, J. ; Betz, H. (1998)
Evidence for a tetrameric structure of recombinant NMDA receptors.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 18 (8)
Artikel, Bibliographie

Laube, Bodo ; Hirai, H. ; Sturgess, M. ; Betz, H. ; Kuhse, J. (1997)
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
In: Neuron, 18 (3)
Artikel, Bibliographie

Hirai, H. ; Kirsch, J. ; Laube, Bodo ; Betz, H. ; Kuhse, J. (1996)
The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.
In: Proceedings of the National Academy of Sciences of the United States of America, 93 (12)
Artikel, Bibliographie

Garcia-Guzman, M. ; Soto, F. ; Laube, Bodo ; Stühmer, W. (1996)
Molecular cloning and functional expression of a novel rat heart P2X purinoceptor.
In: FEBS letters, 388 (2-3)
Artikel, Bibliographie

Laube, Bodo ; Langosch, D. ; Betz, H. ; Schmieden, V. (1995)
Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for beta-amino-acids.
In: Neuroreport, 6 (6)
Artikel, Bibliographie

Laube, Bodo ; Kuhse, J. ; Rundström, N. ; Kirsch, J. ; Schmieden, V. ; Betz, H. (1995)
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors.
In: The Journal of physiology, 483
Artikel, Bibliographie

Kuryatov, A. ; Laube, Bodo ; Betz, H. ; Kuhse, J. (1994)
Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins.
In: Neuron, 12 (6)
Artikel, Bibliographie

Langosch, D. ; Laube, Bodo ; Rundström, N. ; Schmieden, V. ; Bormann, J. ; Betz, H. (1994)
Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia.
In: The EMBO journal, 13 (18)
Artikel, Bibliographie

Betz, H. ; Kuhse, J. ; Fischer, M. ; Schmieden, V. ; Laube, Bodo ; Kuryatov, A. ; Langosch, D. ; Meyer, G. ; Bormann, J. ; Rundström, N. (1994)
Structure, diversity and synaptic localization of inhibitory glycine receptors.
In: Journal of physiology, Paris, 88 (4)
Artikel, Bibliographie

Laube, Bodo ; Kuryatov, A. ; Kuhse, J. ; Betz, H. (1993)
Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues.
In: FEBS letters, 335 (3)
Artikel, Bibliographie

Kuhse, J. ; Laube, Bodo ; Magalei, D. ; Betz, H. (1993)
Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry.
In: Neuron, 11 (6)
Artikel, Bibliographie

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Betz, H. ; Schmitt, B. (1993)
Glutamate receptors of Drosophila melanogaster. Primary structure of a putative NMDA receptor protein expressed in the head of the adult fly.
In: FEBS letters, 324 (2)
Artikel, Bibliographie

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Schloss, P. ; Schmitt, B. ; Betz, H. (1992)
Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system.
In: Proceedings of the National Academy of Sciences of the United States of America, 89 (21)
Artikel, Bibliographie

Müller, M. ; Laube, Bodo ; Burda, H. ; Bruns, V. (1992)
Structure and function of the cochlea in the African mole rat (Cryptomys hottentotus): evidence for a low frequency acoustic fovea.
In: Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 171 (4)
Artikel, Bibliographie

Buchkapitel

Dutertre, S. ; Kuzmin, D. ; Laube, Bodo ; Betz, H.
Hrsg.: Lajtha, A. (2009)
Inhibitory glycine receptors. Neural signal mechanism "Channels: structure, cellular function and disorder".
In: Handbook of Neurochemistry and Molecular Neurobiology
Buchkapitel, Bibliographie

Laube, Bodo ; Betz, H.
Hrsg.: Lennarz, William (2004)
Glycine receptors.
In: Encyclopedia of Biological Chemistry
Buchkapitel, Bibliographie

Dissertation

Pinzuti, Edoardo (2023)
Measuring spectrally resolved information processing in neural data.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00024780
Dissertation, Erstveröffentlichung, Verlagsversion

Hoffmann, Stefanie (2023)
Characterization and establishment of advanced intestinal cell culture models and the evaluation of potential new biomarkers for the prediction of drug-induced intestinal toxicity.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023643
Dissertation, Erstveröffentlichung, Verlagsversion

Joswig, Juliane (2022)
Direct effects of radon exposure on the neural system - a possible target for pain relief.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00020271
Dissertation, Erstveröffentlichung, Verlagsversion

Klink, Axel (2021)
Impact of Low-Dose Ionizing Radiation on Cognitive Abilities in the Mouse : Assessment of Radiation Sensitivity during Pre- and Postnatal Brain Development.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00017535
Dissertation, Erstveröffentlichung, Verlagsversion

Langer, Kai (2021)
Analysis of M4 transmembrane domains in NMDA receptor function: a negative allosteric modulator site at the GluN1-M4 is determining the efficiency of neurosteroid modulation.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00018595
Dissertation, Erstveröffentlichung, Verlagsversion

Bernhard, Max (2021)
Binding Proteins and Receptor Binding Domains as Sensor Elements for Biological and Artificial Nanopores.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00018587
Dissertation, Erstveröffentlichung, Verlagsversion

Kaur, Rajvinder (2021)
DNA breaks regulate neuronal activity: NMDA-receptor and ionizing radiation-mediated DNA double-strand breaks govern activity regulating early-response gene expression.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019655
Dissertation, Erstveröffentlichung, Verlagsversion

Häupl, Katja (2020)
Kurz- und langfristige Auswirkungen strahleninduzierter DNS Doppelstrangbrüche auf das neuronale Netzwerk am in vitro und in vivo Mausmodell.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00015393
Dissertation, Erstveröffentlichung, Verlagsversion

Pflug, Anja (2020)
Hemispheric differences in the control of finger tapping.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011420
Dissertation, Erstveröffentlichung

Häcker, Aline (2020)
Immunzytokine zur Steigerung der antitumoralen Aktivität von CAR-modifizierten Lymphozyten.
Technische Universität Darmstadt
doi: 10.25534/tuprints-00011550
Dissertation, Erstveröffentlichung

Lutz, Henrik (2019)
Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Schönrock, Michael (2019)
Modular design of ionotropic glutamate receptors: Coupling of a viral K+-channel with a glutamate-binding domain.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Köhler, Tim (2019)
Auswirkungen elektromagnetischer Strahlung auf die elektrophysiologischen Eigenschaften neuronaler und kardialer Zellnetzwerke.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Paasch, Georg-Friedrich (2018)
Investigating the Predictive Code of Predictive Coding Theory via Face Identity Expectation in a Learning Task.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Brodski-Guerniero, Alla (2018)
Neural correlates of the use of prior knowledge in predictive coding.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Rau, Kerstin (2018)
Impact of ionising radiation on adult neurogenesis: physiological and cellular effects of low and moderate doses of ionising radiation in neural differentiation distinguished by differentiation phase.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Baltzer, Jan (2018)
Auswirkungen der Gerüstproteine Gephyrin und Collybistin auf die Funktionalität von inhibitorischen Rezeptoren.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Lu, Yiqing (2018)
The Neural Substrate of the Eureka Effect.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Müller, Miriam (2017)
Visual hemineglect and lesion-induced changes of top-down activity in the primary visual cortex.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Barnes, William (2016)
Reversible Visual Hemineglect: the Role of Neural Oscillations in Primary Visual Cortex.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Bressel, Olaf Christian (2016)
Axonal wiring in the mouse olfactory system.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Geider, Kirsten (2015)
Ionotropic glutamate receptor dysfunction in pediatric neurodevelopment.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Längle, Adriana (2014)
Ionotrope Glutamatrezeptoren als Targetstrukturen zur Modulation der Strahlenwirkung bei Glioblastomzellen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Feng, Weijia (2013)
Gamma synchronization and spike timing.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Tamer, Ceyhun (2012)
Role of Interdomain and Intersubunit Contacts for NMDA Receptor Function.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Diese Liste wurde am Thu Mar 28 02:04:50 2024 CET generiert.