B

Bernhard, Max ; Laube, Bodo (2022)
Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs.
In: Scientific Reports, 10
doi: 10.26083/tuprints-00021126
Article, Secondary publication, Publisher's Version

Bernhard, Max (2021)
Binding Proteins and Receptor Binding Domains as Sensor Elements for Biological and Artificial Nanopores.
Technische Universität
doi: 10.26083/tuprints-00018587
Ph.D. Thesis, Primary publication, Publisher's Version

Bernhard, Max ; Laube, Bodo (2020)
Thermophoretic analysis of ligand-specific conformational states of the inhibitory glycine receptor embedded in copolymer nanodiscs.
In: Scientific reports, 10 (1)
doi: 10.1038/s41598-020-73157-2
Article

Bernhard, Max ; Diefenbach, Mathias ; Biesalski, Markus ; Laube, Bodo (2020)
Electrical Sensing of Phosphonates by Functional Coupling of Phosphonate Binding Protein PhnD to Solid-State Nanopores.
In: ACS sensors, 5 (1)
doi: 10.1021/acssensors.9b02097
Article

Bledsoe, Douglas ; Vacca, Bryanna ; Laube, Bodo ; Klein, Bradley G. ; Costa, Blaise (2019)
Ligand binding domain interface: A tipping point for pharmacological agents binding with GluN1/2A subunit containing NMDA receptors.
In: European journal of pharmacology, 844
doi: 10.1016/j.ejphar.2018.12.023
Article

Brodski-Guerniero, Alla (2018)
Neural correlates of the use of prior knowledge in predictive coding.
Technische Universität
Ph.D. Thesis, Primary publication

Baltzer, Jan (2018)
Auswirkungen der Gerüstproteine Gephyrin und Collybistin auf die Funktionalität von inhibitorischen Rezeptoren.
Technische Universität
Ph.D. Thesis, Primary publication

Bernhard, Max ; Laube, Bodo (2017)
Functional Coupling of Bacterial Binding Protein with the Channel Pore of an Ionotropic Glutamate Receptor.
In: Biophysical journal, 112 (3)
Article

Bledsoe, Douglas ; Tamer, Ceyhun ; Mesic, Ivana ; Madry, Christian ; Klein, Bradley G. ; Laube, Bodo ; Costa, Blaise M. (2017)
Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity.
In: Frontiers in pharmacology, 8
Article

Barnes, William (2016)
Reversible Visual Hemineglect: the Role of Neural Oscillations in Primary Visual Cortex.
Technische Universität
Ph.D. Thesis, Primary publication

Bressel, Olaf Christian (2016)
Axonal wiring in the mouse olfactory system.
Technische Universität
Ph.D. Thesis, Primary publication

Betz, Heinrich ; Laube, Bodo (2006)
Glycine receptors: recent insights into their structural organization and functional diversity.
In: Journal of neurochemistry, 97 (6)
Article

Büttner, C. ; Sadtler, S. ; Leyendecker, A. ; Laube, Bodo ; Griffon, N. ; Betz, H. ; Schmalzing, G. (2001)
Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors.
In: The Journal of biological chemistry, 276 (46)
Article

Betz, H. ; Kuhse, J. ; Schmieden, V. ; Laube, Bodo ; Kirsch, J. ; Harvey, R. J. (1999)
Structure and functions of inhibitory and excitatory glycine receptors.
In: Annals of the New York Academy of Sciences, 868
Article

Betz, H. ; Kuhse, J. ; Fischer, M. ; Schmieden, V. ; Laube, Bodo ; Kuryatov, A. ; Langosch, D. ; Meyer, G. ; Bormann, J. ; Rundström, N. (1994)
Structure, diversity and synaptic localization of inhibitory glycine receptors.
In: Journal of physiology, Paris, 88 (4)
Article

C

Costa, Blaise Mathias ; Irvine, Mark W. ; Fang, Guangyu ; Eaves, Richard J. ; Mayo-Martin, Maria Belen ; Laube, Bodo ; Jane, David E. ; Monaghan, Daniel T. (2012)
Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid.
In: Neuropharmacology, 62 (4)
Article

D

Dutertre, Sébastien ; Drwal, Malgorzata ; Laube, Bodo ; Betz, Heinrich (2012)
Probing the pharmacological properties of distinct subunit interfaces within heteromeric glycine receptors reveals a functional ββ agonist binding site.
In: Journal of neurochemistry, 122 (1)
Article

Dutertre, S. ; Kuzmin, D. ; Laube, Bodo ; Betz, H.
ed.: Lajtha, A. (2009)
Inhibitory glycine receptors. Neural signal mechanism "Channels: structure, cellular function and disorder".
In: Handbook of Neurochemistry and Molecular Neurobiology
Book Section

E

Endele, Sabine ; Rosenberger, Georg ; Geider, Kirsten ; Popp, Bernt ; Tamer, Ceyhun ; Stefanova, Irina ; Milh, Mathieu ; Kortüm, Fanny ; Fritsch, Angela ; Pientka, Friederike K. ; Hellenbroich, Yorck ; Kalscheuer, Vera M. ; Kohlhase, Jürgen ; Moog, Ute ; Rappold, Gudrun ; Rauch, Anita ; Ropers, Hans-Hilger ; Spiczak, Sarah von ; Tönnies, Holger ; Villeneuve, Nathalie ; Villard, Laurent ; Zabel, Bernhard ; Zenker, Martin ; Laube, Bodo ; Reis, André ; Wieczorek, Dagmar ; Maldergem, Lionel van ; Kutsche, Kerstin (2010)
Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes.
In: Nature genetics, 42 (11)
Article

F

Feng, Weijia (2013)
Gamma synchronization and spike timing.
TU Darmstadt
Ph.D. Thesis, Primary publication

Foucaud, Bernard ; Laube, Bodo ; Schemm, Rudolf ; Kreimeyer, Annett ; Goeldner, Maurice ; Betz, Heinrich (2003)
Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling.
In: The Journal of biological chemistry, 278 (26)
Article

G

Geider, Kirsten (2015)
Ionotropic glutamate receptor dysfunction in pediatric neurodevelopment.
TU Darmstadt
Ph.D. Thesis, Primary publication

Grudzinska, Joanna ; Schumann, Tanja ; Schemm, Rudolf ; Betz, Heinrich ; Laube, Bodo (2008)
Mutations within the agonist-binding site convert the homomeric alpha1 glycine receptor into a Zn2+-activated chloride channel.
In: Channels (Austin, Tex.), 2 (1)
Article

Grudzinska, Joanna ; Schemm, Rudolf ; Haeger, Svenja ; Nicke, Annette ; Schmalzing, Guenther ; Betz, Heinrich ; Laube, Bodo (2005)
The beta subunit determines the ligand binding properties of synaptic glycine receptors.
In: Neuron, 45 (5)
Article

Gomeza, Jesús ; Ohno, Koji ; Hülsmann, Swen ; Armsen, Wencke ; Eulenburg, Volker ; Richter, Diethelm W. ; Laube, Bodo ; Betz, Heinrich (2003)
Deletion of the mouse glycine transporter 2 results in a hyperekplexia phenotype and postnatal lethality.
In: Neuron, 40 (4)
Article

Garcia-Guzman, M. ; Soto, F. ; Laube, Bodo ; Stühmer, W. (1996)
Molecular cloning and functional expression of a novel rat heart P2X purinoceptor.
In: FEBS letters, 388 (2-3)
Article

H

Hoffmann, Stefanie (2023)
Characterization and establishment of advanced intestinal cell culture models and the evaluation of potential new biomarkers for the prediction of drug-induced intestinal toxicity.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023643
Ph.D. Thesis, Primary publication, Publisher's Version

Häupl, Katja (2020)
Kurz- und langfristige Auswirkungen strahleninduzierter DNS Doppelstrangbrüche auf das neuronale Netzwerk am in vitro und in vivo Mausmodell.
Technische Universität
doi: 10.25534/tuprints-00015393
Ph.D. Thesis, Primary publication, Publisher's Version

Häcker, Aline (2020)
Immunzytokine zur Steigerung der antitumoralen Aktivität von CAR-modifizierten Lymphozyten.
Technische Universität
doi: 10.25534/tuprints-00011550
Ph.D. Thesis, Primary publication

Haeger, Svenja ; Kuzmin, Dmitry ; Detro-Dassen, Silvia ; Lang, Niklas ; Kilb, Michael ; Tsetlin, Victor ; Betz, Heinrich ; Laube, Bodo ; Schmalzing, Günther (2010)
An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors.
In: Nature structural & molecular biology, 17 (1)
Article

Hirzel, Klaus ; Müller, Ulrike ; Latal, A.Tobias ; Hülsmann, Swen ; Grudzinska, Joanna ; Seeliger, Mathias W. ; Betz, Heinrich ; Laube, Bodo (2006)
Hyperekplexia phenotype of glycine receptor alpha1 subunit mutant mice identifies Zn(2+) as an essential endogenous modulator of glycinergic neurotransmission.
In: Neuron, 52 (4)
Article

Harvey, R. J. ; Schmieden, V. ; Holst, A. von ; Laube, Bodo ; Rohrer, H. ; Betz, H. (2000)
Glycine receptors containing the alpha4 subunit in the embryonic sympathetic nervous system, spinal cord and male genital ridge.
In: The European journal of neuroscience, 12 (3)
Article

Honer, M. ; Benke, D. ; Laube, Bodo ; Kuhse, J. ; Heckendorn, R. ; Allgeier, H. ; Angst, C. ; Monyer, H. ; Seeburg, P. H. ; Betz, H. ; Möhler, H. (1998)
Differentiation of glycine antagonist sites of N-methyl-D-aspartate receptor subtypes. Preferential interaction of CGP 61594 with NR1/2B receptors.
In: The Journal of biological chemistry, 273 (18)
Article

Hirai, H. ; Kirsch, J. ; Laube, Bodo ; Betz, H. ; Kuhse, J. (1996)
The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.
In: Proceedings of the National Academy of Sciences of the United States of America, 93 (12)
Article

I

Ivanovic, A. ; Reiländer, H. ; Laube, Bodo ; Kuhse, J. (1998)
Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit.
In: The Journal of biological chemistry, 273 (32)
Article

J

Joswig, Juliane (2022)
Direct effects of radon exposure on the neural system - a possible target for pain relief.
Technische Universität
doi: 10.26083/tuprints-00020271
Ph.D. Thesis, Primary publication, Publisher's Version

K

Klink, Axel (2021)
Impact of Low-Dose Ionizing Radiation on Cognitive Abilities in the Mouse : Assessment of Radiation Sensitivity during Pre- and Postnatal Brain Development.
Technische Universität
doi: 10.26083/tuprints-00017535
Ph.D. Thesis, Primary publication, Publisher's Version

Kaur, Rajvinder (2021)
DNA breaks regulate neuronal activity: NMDA-receptor and ionizing radiation-mediated DNA double-strand breaks govern activity regulating early-response gene expression.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019655
Ph.D. Thesis, Primary publication, Publisher's Version

Köhler, Tim (2019)
Auswirkungen elektromagnetischer Strahlung auf die elektrophysiologischen Eigenschaften neuronaler und kardialer Zellnetzwerke.
Technische Universität
Ph.D. Thesis, Primary publication

Kallenborn-Gerhardt, Wiebke ; Lu, Ruirui ; Lorenz, Jana ; Gao, Wei ; Weiland, Jessica ; Del Turco, Domenico ; Deller, Thomas ; Laube, Bodo ; Betz, Heinrich ; Geisslinger, Gerd ; Schmidtko, Achim (2012)
Prolonged zymosan-induced inflammatory pain hypersensitivity in mice lacking glycine receptor alpha2.
In: Behavioural brain research, 226 (1)
Article

Kondratskaya, Elena L. ; Betz, Heinrich ; Krishtal, Oleg A. ; Laube, Bodo (2005)
The beta subunit increases the ginkgolide B sensitivity of inhibitory glycine receptors.
In: Neuropharmacology, 49 (6)
Article

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. (1999)
Reactive affinity probes for the mapping of the glycine-binding site of the NMDA receptor NR1 subunit.
In: Journal of receptor and signal transduction research, 19 (1-4)
Article

Kreimeyer, A. ; Laube, Bodo ; Sturgess, M. ; Goeldner, M. ; Foucaud, B. (1999)
Evaluation and biological properties of reactive ligands for the mapping of the glycine site on the N-methyl-D-aspartate (NMDA) receptor.
In: Journal of medicinal chemistry, 42 (21)
Article

Kins, S. ; Kuhse, J. ; Laube, Bodo ; Betz, H. ; Kirsch, J. (1999)
Incorporation of a gephyrin-binding motif targets NMDA receptors to gephyrin-rich domains in HEK 293 cells.
In: The European journal of neuroscience, 11 (2)
Article

Kneussel, M. ; Brandstätter, J. H. ; Laube, Bodo ; Stahl, S. ; Müller, U. ; Betz, H. (1999)
Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 19 (21)
Article

Kuryatov, A. ; Laube, Bodo ; Betz, H. ; Kuhse, J. (1994)
Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins.
In: Neuron, 12 (6)
Article

Kuhse, J. ; Laube, Bodo ; Magalei, D. ; Betz, H. (1993)
Assembly of the inhibitory glycine receptor: identification of amino acid sequence motifs governing subunit stoichiometry.
In: Neuron, 11 (6)
Article

L

Langer, Kai ; Müller-Längle, Adriana ; Wempe, Jannik ; Laube, Bodo (2022)
Analysis of M4 Transmembrane Segments in NMDA Receptor Function: A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.
In: Frontiers in Pharmacology, 12
doi: 10.26083/tuprints-00020785
Article, Secondary publication, Publisher's Version

Langer, Kai (2021)
Analysis of M4 transmembrane domains in NMDA receptor function: a negative allosteric modulator site at the GluN1-M4 is determining the efficiency of neurosteroid modulation.
Technische Universität
doi: 10.26083/tuprints-00018595
Ph.D. Thesis, Primary publication, Publisher's Version

Langer, Kai ; Müller-Längle, Adriana ; Wempe, Jannik ; Laube, Bodo (2021)
Analysis of M4 Transmembrane Segments in NMDA Receptor Function : A Negative Allosteric Modulatory Site at the GluN1 M4 is Determining the Efficiency of Neurosteroid Modulation.
In: Frontiers in pharmacology, 12
doi: 10.3389/fphar.2021.769046
Article

Lutz, Henrik (2019)
Identification and impact of Topoisomerase II β induced DNA double-strand breaks in Glioblastoma multiforme: NMDA-receptor signaling pathway as target structure.
Technische Universität
Ph.D. Thesis, Primary publication

Lutz, Henrik ; Nguyen, Thy ; Joswig, Juliane ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor Signaling Mediates cFos Expression via Top2β-Induced DSBs in Glioblastoma Cells.
In: Cancers, 11 (3)
doi: 10.3390/cancers11030306
Article, Secondary publication

Lu, Yiqing (2018)
The Neural Substrate of the Eureka Effect.
Technische Universität
Ph.D. Thesis, Primary publication

Lemke, Johannes R. ; Geider, Kirsten ; Helbig, Katherine L. ; Heyne, Henrike O. ; Schütz, Hannah ; Hentschel, Julia ; Courage, Carolina ; Depienne, Christel ; Nava, Caroline ; Heron, Delphine ; Møller, Rikke S. ; Hjalgrim, Helle ; Lal, Dennis ; Neubauer, Bernd A. ; Nürnberg, Peter ; Thiele, Holger ; Kurlemann, Gerhard ; Arnold, Georgianne L. ; Bhambhani, Vikas ; Bartholdi, Deborah ; Pedurupillay, Christeen Ramane J. ; Misceo, Doriana ; Frengen, Eirik ; Strømme, Petter ; Dlugos, Dennis J. ; Doherty, Emily S. ; Bijlsma, Emilia K. ; Ruivenkamp, Claudia A. ; Hoffer, Mariette J. V. ; Goldstein, Amy ; Rajan, Deepa S. ; Narayanan, Vinodh ; Ramsey, Keri ; Belnap, Newell ; Schrauwen, Isabelle ; Richholt, Ryan ; Koeleman, Bobby P. C. ; Sá, Joaquim ; Mendonça, Carla ; Kovel, Carolien de ; Weckhuysen, Sarah ; Hardies, Katia ; De Jonghe, Peter ; De Meirleir, Linda ; Milh, Mathieu ; Badens, Catherine ; Lebrun, Marine ; Busa, Tiffany ; Francannet, Christine ; Piton, Amélie ; Riesch, Erik ; Biskup, Saskia ; Vogt, Heinrich ; Dorn, Thomas ; Helbig, Ingo ; Michaud, Jacques L. ; Laube, Bodo ; Syrbe, Steffen (2016)
Delineating the GRIN1 phenotypic spectrum: A distinct genetic NMDA receptor encephalopathy.
In: Neurology, 86 (23)
Article

Lynagh, Timothy ; Beech, Robin N. ; Lalande, Maryline J. ; Keller, Kevin ; Cromer, Brett A. ; Wolstenholme, Adrian J. ; Laube, Bodo (2015)
Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels.
In: Scientific reports, 24 (5)
Article

Lynagh, Timothy ; Laube, Bodo (2014)
Opposing effects of the anesthetic propofol at pentameric ligand-gated ion channels mediated by a common site.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 (6)
Article

Lemke, Johannes R. ; Hendrickx, Rik ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Harvey, Robert J. ; James, Victoria M. ; Pepler, Alex ; Steiner, Isabelle ; Hörtnagel, Konstanze ; Neidhardt, John ; Ruf, Susanne ; Wolff, Markus ; Bartholdi, Deborah ; Caraballo, Roberto ; Platzer, Konrad ; Suls, Arvid ; De Jonghe, Peter ; Biskup, Saskia ; Weckhuysen, Sarah (2014)
GRIN2B mutations in West syndrome and intellectual disability with focal epilepsy.
In: Annals of neurology, 75 (1)
Article

Längle, Adriana (2014)
Ionotrope Glutamatrezeptoren als Targetstrukturen zur Modulation der Strahlenwirkung bei Glioblastomzellen.
TU Darmstadt
Ph.D. Thesis, Primary publication

Lynagh, Timothy ; Cromer, Brett A. ; Dufour, Vanessa ; Laube, Bodo (2014)
Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics.
In: International journal for parasitology. Drugs and drug resistance, 4 (3)
Article

Lynagh, Timothy ; Kunz, Alexander ; Laube, Bodo (2013)
Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activation.
In: ACS chemical neuroscience, 4 (11)
Article

Lemke, Johannes R. ; Lal, Dennis ; Reinthaler, Eva M. ; Steiner, Isabelle ; Nothnagel, Michael ; Alber, Michael ; Geider, Kirsten ; Laube, Bodo ; Schwake, Michael ; Finsterwalder, Katrin ; Franke, Andre ; Schilhabel, Markus ; Jähn, Johanna A. ; Muhle, Hiltrud ; Boor, Rainer ; Paesschen, Wim van ; Caraballo, Roberto ; Fejerman, Natalio ; Weckhuysen, Sarah ; De Jonghe, Peter ; Larsen, Jan ; Møller, Rikke S. ; Hjalgrim, Helle ; Addis, Laura ; Tang, Shan ; Hughes, Elaine ; Pal, Deb K. ; Veri, Kadi ; Vaher, Ulvi ; Talvik, Tiina ; Dimova, Petia ; Guerrero López, Rosa ; Serratosa, José M. ; Linnankivi, Tarja ; Lehesjoki, Anna-Elina ; Ruf, Susanne ; Wolff, Markus ; Buerki, Sarah ; Wohlrab, Gabriele ; Kroell, Judith ; Datta, Alexandre N. ; Fiedler, Barbara ; Kurlemann, Gerhard ; Kluger, Gerhard ; Hahn, Andreas ; Haberlandt, D. Edda ; Kutzer, Christina ; Sperner, Jürgen ; Becker, Felicitas ; Weber, Yvonne G. ; Feucht, Martha ; Steinböck, Hannelore ; Neophythou, Birgit ; Ronen, Gabriel M. ; Gruber-Sedlmayr, Ursula ; Geldner, Julia ; Harvey, Robert J. ; Hoffmann, Per ; Herms, Stefan ; Altmüller, Janine ; Toliat, Mohammad R. ; Thiele, Holger ; Nürnberg, Peter ; Wilhelm, Christian ; Stephani, Ulrich ; Helbig, Ingo ; Lerche, Holger ; Zimprich, Fritz ; Neubauer, Bernd A. ; Biskup, Saskia ; Spiczak, Sarah von (2013)
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Nature genetics, 45 (9)
Article

Laube, Bodo ; Betz, Heinrich (2009)
Die duale Rolle des Neurotransmitters Glyzin im zentralen Nervensystem.
In: Jahrbuch 2009 der Max-Planck-Gesellschaft
Article

Laube, Bodo (2007)
Dr. Jekyll & Mr. Hyde - das janusköpfige Zink.
In: BIOforum, 30 (3)
Article

Laube, Bodo ; Schemm, Rudolf ; Betz, Heinrich (2004)
Molecular determinants of ligand discrimination in the glutamate-binding pocket of the NMDA receptor.
In: Neuropharmacology, 47 (7)
Article

Laube, Bodo ; Betz, H.
ed.: Lennarz, William (2004)
Glycine receptors.
In: Encyclopedia of Biological Chemistry
Book Section

Laube, Bodo ; Maksay, Gábor ; Schemm, Rudolf ; Betz, Heinrich (2002)
Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?
In: Trends in pharmacological sciences, 23 (11)
Article

Laube, Bodo (2002)
Potentiation of inhibitory glycinergic neurotransmission by Zn2+: a synergistic interplay between presynaptic P2X2 and postsynaptic glycine receptors.
In: The European journal of neuroscience, 16 (6)
Article

Laube, Bodo ; Kuhse, J. ; Betz, H. (2000)
Kinetic and mutational analysis of Zn2+ modulation of recombinant human inhibitory glycine receptors.
In: The Journal of physiology, (2)
doi: 10.1111/j.1469-7793.2000.t01-1-00215.x
Article

Laube, Bodo ; Betz, H. (1999)
Purification and heterologous expression of inhibitory glycine receptors.
In: Methods in enzymology, 294
Article

Laube, Bodo ; Kuhse, J. ; Betz, H. (1998)
Evidence for a tetrameric structure of recombinant NMDA receptors.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 18 (8)
Article

Laube, Bodo ; Hirai, H. ; Sturgess, M. ; Betz, H. ; Kuhse, J. (1997)
Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit.
In: Neuron, 18 (3)
Article

Laube, Bodo ; Langosch, D. ; Betz, H. ; Schmieden, V. (1995)
Hyperekplexia mutations of the glycine receptor unmask the inhibitory subsite for beta-amino-acids.
In: Neuroreport, 6 (6)
Article

Laube, Bodo ; Kuhse, J. ; Rundström, N. ; Kirsch, J. ; Schmieden, V. ; Betz, H. (1995)
Modulation by zinc ions of native rat and recombinant human inhibitory glycine receptors.
In: The Journal of physiology, 483
Article

Langosch, D. ; Laube, Bodo ; Rundström, N. ; Schmieden, V. ; Bormann, J. ; Betz, H. (1994)
Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia.
In: The EMBO journal, 13 (18)
Article

Laube, Bodo ; Kuryatov, A. ; Kuhse, J. ; Betz, H. (1993)
Glycine-glutamate interactions at the NMDA receptor: role of cysteine residues.
In: FEBS letters, 335 (3)
Article

M

Müller-Längle, Adriana ; Lutz, Henrik ; Hehlgans, Stephanie ; Rödel, Franz ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells-A Potential Target for Adjuvant Radiotherapy.
In: Cancers, 11 (4)
doi: 10.3390/cancers11040503
Article

Müller-Längle, Adriana ; Lutz, Henrik ; Hehlgans, Stephanie ; Rödel, Franz ; Rau, Kerstin ; Laube, Bodo (2019)
NMDA Receptor-Mediated Signaling Pathways Enhance Radiation Resistance, Survival and Migration in Glioblastoma Cells — A Potential Target for Adjuvant Radiotherapy.
In: Cancers, 11 (4)
doi: 10.3390/cancers11040503
Article, Secondary publication

Müller, Miriam (2017)
Visual hemineglect and lesion-induced changes of top-down activity in the primary visual cortex.
Technische Universität
Ph.D. Thesis, Primary publication

Mesic, Ivana ; Madry, Christian ; Geider, Kirsten ; Bernhard, Max ; Betz, Heinrich ; Laube, Bodo (2016)
The N-terminal domain of the GluN3A subunit determines the efficacy of glycine-activated NMDA receptors.
In: Neuropharmacology, 105
Article

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo (2010)
Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca-Dependent Outward Rectification.
In: Frontiers in molecular neuroscience, 3
Article

Maksay, Gábor ; Laube, Bodo ; Schemm, Rudolf ; Grudzinska, Joanna ; Drwal, Malgorzata ; Betz, Heinrich (2009)
Different binding modes of tropeines mediating inhibition and potentiation of alpha1 glycine receptors.
In: Journal of neurochemistry, 109 (6)
Article

Madry, Christian ; Betz, Heinrich ; Geiger, Jörg R. P. ; Laube, Bodo (2008)
Supralinear potentiation of NR1/NR3A excitatory glycine receptors by Zn2+ and NR1 antagonist.
In: Proceedings of the National Academy of Sciences of the United States of America, 105 (34)
Article

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo ; Nemes, Péter (2008)
Hyperekplexia mutation R271L of alpha1 glycine receptors potentiates allosteric interactions of nortropeines, propofol and glycine with [3H]strychnine binding.
In: Neurochemistry international, 52 (1-2)
Article

Madry, Christian ; Mesic, Ivana ; Betz, Heinrich ; Laube, Bodo (2007)
The N-terminal domains of both NR1 and NR2 subunits determine allosteric Zn2+ inhibition and glycine affinity of N-methyl-D-aspartate receptors.
In: Molecular pharmacology, 72 (6)
Article

Madry, Christian ; Mesic, Ivana ; Bartholomäus, Ingo ; Nicke, Annette ; Betz, Heinrich ; Laube, Bodo (2007)
Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function.
In: Biochemical and biophysical research communications, 354 (1)
Article

Maier, Wolfgang ; Schemm, Rudolf ; Grewer, Christof ; Laube, Bodo (2007)
Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.
In: The Journal of biological chemistry, 282 (3)
Article

Maier, Wolfgang ; Corrie, John E. T. ; Papageorgiou, George ; Laube, Bodo ; Grewer, Christof (2005)
Comparative analysis of inhibitory effects of caged ligands for the NMDA receptor.
In: Journal of neuroscience methods, 142 (1)
Article

Maksay, Gábor ; Bíró, Tímea ; Laube, Bodo (2002)
Hyperekplexia mutation of glycine receptors: decreased gating efficacy with altered binding thermodynamics.
In: Biochemical pharmacology, 64 (2)
Article

Maksay, G. ; Laube, Bodo ; Betz, H. (2001)
Subunit-specific modulation of glycine receptors by neurosteroids.
In: Neuropharmacology, 41 (3)
Article

Maksay, G. ; Laube, Bodo ; Betz, H. (1999)
Selective blocking effects of tropisetron and atropine on recombinant glycine receptors.
In: Journal of neurochemistry, 73 (2)
Article

Müller, M. ; Laube, Bodo ; Burda, H. ; Bruns, V. (1992)
Structure and function of the cochlea in the African mole rat (Cryptomys hottentotus): evidence for a low frequency acoustic fovea.
In: Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 171 (4)
Article

N

Nikolic, Z. ; Laube, Bodo ; Weber, R. G. ; Lichter, P. ; Kioschis, P. ; Poustka, A. ; Mülhardt, C. ; Becker, C. M. (1998)
The human glycine receptor subunit alpha3. Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts.
In: The Journal of biological chemistry, 273 (31)
Article

O

O'Shea, Sean Michael ; Becker, Lore ; Weiher, Hans ; Betz, Heinrich ; Laube, Bodo (2004)
Propofol restores the function of "hyperekplexic" mutant glycine receptors in Xenopus oocytes and mice.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 24 (9)
Article

Ortinau, Stefanie ; Laube, Bodo ; Zimmermann, Herbert (2003)
ATP inhibits NMDA receptors after heterologous expression and in cultured hippocampal neurons and attenuates NMDA-mediated neurotoxicity.
In: The Journal of neuroscience : the official journal of the Society for Neuroscience, 23 (12)
Article

P

Pflug, Anja (2020)
Hemispheric differences in the control of finger tapping.
Technische Universität
doi: 10.25534/tuprints-00011420
Ph.D. Thesis, Primary publication

Paasch, Georg-Friedrich (2018)
Investigating the Predictive Code of Predictive Coding Theory via Face Identity Expectation in a Learning Task.
Technische Universität
Ph.D. Thesis, Primary publication

Platzer, Konrad ; Yuan, Hongjie ; Schütz, Hannah ; Winschel, Alexander ; Chen, Wenjuan ; Hu, Chun ; Kusumoto, Hirofumi ; Heyne, Henrike O. ; Helbig, Katherine L. ; Tang, Sha ; Willing, Marcia C. ; Tinkle, Brad T. ; Adams, Darius J. ; Depienne, Christel ; Keren, Boris ; Mignot, Cyril ; Frengen, Eirik ; Strømme, Petter ; Biskup, Saskia ; Döcker, Dennis ; Strom, Tim M. ; Mefford, Heather C. ; Myers, Candace T. ; Muir, Alison M. ; LaCroix, Amy ; Sadleir, Lynette ; Scheffer, Ingrid E. ; Brilstra, Eva ; Haelst, Mieke M. van ; Smagt, Jasper J. van der ; Bok, Levinus A. ; Møller, Rikke S. ; Jensen, Uffe B. ; Millichap, John J. ; Berg, Anne T. ; Goldberg, Ethan M. ; De Bie, Isabelle ; Fox, Stephanie ; Major, Philippe ; Jones, Julie R. ; Zackai, Elaine H. ; Abou Jamra, Rami ; Rolfs, Arndt ; Leventer, Richard J. ; Lawson, John A. ; Roscioli, Tony ; Jansen, Floor E. ; Ranza, Emmanuelle ; Korff, Christian M. ; Lehesjoki, Anna-Elina ; Courage, Carolina ; Linnankivi, Tarja ; Smith, Douglas R. ; Stanley, Christine ; Mintz, Mark ; McKnight, Dianalee ; Decker, Amy ; Tan, Wen-Hann ; Tarnopolsky, Mark A. ; Brady, Lauren I. ; Wolff, Markus ; Dondit, Lutz ; Pedro, Helio F. ; Parisotto, Sarah E. ; Jones, Kelly L. ; Patel, Anup D. ; Franz, David N. ; Vanzo, Rena ; Marco, Elysa ; Ranells, Judith D. ; Di Donato, Nataliya ; Dobyns, William B. ; Laube, Bodo ; Traynelis, Stephen F. ; Lemke, Johannes R. (2017)
GRIN2B encephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects.
In: Journal of medical genetics, 54 (7)
Article

Pult, Frauke ; Fallah, Ghada ; Braam, Ursula ; Detro-Dassen, Silvia ; Niculescu, Cristina ; Laube, Bodo ; Schmalzing, Günther (2011)
Robust post-translocational N-glycosylation at the extreme C-terminus of membrane and secreted proteins in Xenopus laevis oocytes and HEK293 cells.
In: Glycobiology, 21 (9)
Article

Papadopoulos, Theofilos ; Korte, Martin ; Eulenburg, Volker ; Kubota, Hisahiko ; Retiounskaia, Marina ; Harvey, Robert J. ; Harvey, Kirsten ; O'Sullivan, Gregory A. ; Laube, Bodo ; Hülsmann, Swen ; Geiger, Jörg R. P. ; Betz, Heinrich (2007)
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice.
In: The EMBO journal, 26 (17)
Article

Perret, P. ; Laube, Bodo ; Schemm, R. ; Betz, H. ; Goeldner, M. ; Foucaud, B. (2002)
Affinity labeling of cysteine-mutants evidences contact residues in modeled receptor binding sites.
In: Journal of receptor and signal transduction research, 22 (1-4)
Article

R

Richter, Max C. ; Ludewig, Susann ; Winschel, Alex ; Abel, Tobias ; Bold, Charlotte ; Salzburger, Leonie R. ; Klein, Susanne ; Han, Kang ; Weyer, Sascha W. ; Fritz, Ann-Kristina ; Laube, Bodo ; Wolfer, David P. ; Buchholz, Christian J. ; Korte, Martin ; Müller, Ulrike C. (2018)
Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.
In: The EMBO journal, 37 (11)
doi: 10.15252/embj.201798335
Article

Rau, Kerstin (2018)
Impact of ionising radiation on adult neurogenesis: physiological and cellular effects of low and moderate doses of ionising radiation in neural differentiation distinguished by differentiation phase.
Technische Universität
Ph.D. Thesis, Primary publication

S

Schönrock, Michael ; Thiel, Gerhard ; Laube, Bodo (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.
In: Communications biology, 2
doi: 10.1038/s42003-019-0320-y
Article

Schönrock, Michael (2019)
Modular design of ionotropic glutamate receptors: Coupling of a viral K+-channel with a glutamate-binding domain.
Technische Universität
Ph.D. Thesis, Primary publication

Schönrock, Michael ; Thiel, Gerhard ; Laube, Bodo (2019)
Coupling of a viral K+-channel with a glutamate-binding-domain highlights the modular design of ionotropic glutamate-receptors.
In: Communications Biology, 2 (1)
doi: 10.1038/s42003-019-0320-y
Article, Secondary publication

Schoenrock, Michael ; Poci, Alina ; Thiel, Gerhard ; Laube, Bodo (2017)
Design of a Glutamate-Activated Potassium Channel upon Fusion of the Ligand-Binding Domain of the Mammalian AMPA Receptor Glua1 to the Channel Pore of the Viral ATCV-1 KCV K+ Channel.
In: Biophysical journal, 112 (3)
Article

Spiczak, Sarah von ; Lal, D. ; Reinthaler, E. M. ; Steiner, I. ; Nothnagel, M. ; Laube, Bodo ; Schwake, M. ; Hoffmann, P. ; Herms, S. ; Altmüller, J. ; Toliat, M. R. ; Thiele, H. ; Nürnberg, P. ; Wilhelm, C. ; Stephani, U. ; Helbig, I. ; Lerche, H. ; Zimprich, F. ; Neubauer, B. A. ; Biskup, S. ; Lemke, J. R. (2013)
Mutations in GRIN2A cause idiopathic focal epilepsy with rolandic spikes.
In: Epilepsia, 54
Article

Schumann, Tanja ; Grudzinska, Joanna ; Kuzmin, Dmitry ; Betz, Heinrich ; Laube, Bodo (2009)
Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator.
In: Neuropharmacology, 56 (1)
Article

Schüler, Thomas ; Mesic, Ivana ; Madry, Christian ; Bartholomäus, Ingo ; Laube, Bodo (2008)
Formation of NR1/NR2 and NR1/NR3 heterodimers constitutes the initial step in N-methyl-D-aspartate receptor assembly.
In: The Journal of biological chemistry, 283 (1)
Article

Sadtler, Sven ; Laube, Bodo ; Lashub, Alhassan ; Nicke, Annette ; Betz, Heinrich ; Schmalzing, Günther (2003)
A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit.
In: The Journal of biological chemistry, 278 (19)
Article

T

Tamer, Ceyhun (2012)
Role of Interdomain and Intersubunit Contacts for NMDA Receptor Function.
TU Darmstadt
Ph.D. Thesis, Primary publication

U

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Betz, H. ; Schmitt, B. (1993)
Glutamate receptors of Drosophila melanogaster. Primary structure of a putative NMDA receptor protein expressed in the head of the adult fly.
In: FEBS letters, 324 (2)
Article

Ultsch, A. ; Schuster, C. M. ; Laube, Bodo ; Schloss, P. ; Schmitt, B. ; Betz, H. (1992)
Glutamate receptors of Drosophila melanogaster: cloning of a kainate-selective subunit expressed in the central nervous system.
In: Proceedings of the National Academy of Sciences of the United States of America, 89 (21)
Article

W

Wittekindt, B. ; Malany, S. ; Schemm, R. ; Otvos, L. ; Maccecchini, M. L. ; Laube, Bodo ; Betz, H. (2001)
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition.
In: Neuropharmacology, 41 (6)
Article

Wittekindt, B. ; Betz, H. ; Laube, Bodo (2000)
Subunit-dependent inhibition of recombinant rodent N-methyl-D-aspartate receptors by a HIV-1 glycoprotein 120 derived peptide.
In: Neuroscience letters, 280 (2)
Article