TU Darmstadt / ULB / TUbiblio

Items in division

Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Creators | Date | Item Type | Language | No Grouping
Jump to: B | C | E | F | G | J | K | L | M | O | P | R | S | T
Number of items at this level (without sub-levels): 43.


Benary, Manuela and Bohn, Stefan and Lüthen, Mareen and Nolis, Ilias K. and Blüthgen, Nils and Loewer, Alexander (2020):
Disentangling Pro-mitotic Signaling during Cell Cycle Progression using Time-Resolved Single-Cell Imaging.
In: Cell reports, 31 (2), p. 107514. ISSN 2211-1247,
DOI: 10.1016/j.celrep.2020.03.078,

Batchelor, Eric and Loewer, Alexander (2017):
Recent progress and open challenges in modeling p53 dynamics in single cells.
In: Current opinion in systems biology, 3, pp. 54-59. ISSN 2452-3100,

Borcherds, Wade and Theillet, François-Xavier and Katzer, Andrea and Finzel, Ana and Mishall, Katie M. and Powell, Anne T. and Wu, Hongwei and Manieri, Wanda and Dieterich, Christoph and Selenko, Philipp and Loewer, Alexander and Daughdrill, Gary W. (2014):
Disorder and residual helicity alter p53-Mdm2 binding affinity and signaling in cells.
In: Nature chemical biology, 10 (12), pp. 1000-2. ISSN 1552-4469,

Batchelor, Eric and Loewer, Alexander and Mock, Caroline and Lahav, Galit (2011):
Stimulus-dependent dynamics of p53 in single cells.
In: Molecular systems biology, 7, p. 488. ISSN 1744-4292,

Batchelor, Eric and Loewer, Alexander and Lahav, Galit (2009):
The ups and downs of p53: understanding protein dynamics in single cells.
In: Nature reviews. Cancer, 9 (5), pp. 371-7. ISSN 1474-1768,

Batchelor, Eric and Mock, Caroline S. and Bhan, Irun and Loewer, Alexander and Lahav, Galit (2008):
Recurrent initiation: a mechanism for triggering p53 pulses in response to DNA damage.
In: Molecular cell, 30 (3), pp. 277-89. ISSN 1097-4164,


Chamiolo, Jasmine and Fang, Ge‐min and Hövelmann, Felix and Friedrich, Dhana and Knoll, Andrea and Loewer, Alexander and Seitz, Oliver (2019):
Comparing Agent‐Based Delivery of DNA and PNA Forced Intercalation (FIT) Probes for Multicolor mRNA Imaging.
In: ChemBioChem, 20 (4), pp. 595-604. ISSN 1439-4227,
DOI: 10.1002/cbic.201800526,


Erbeldinger, Nadine (2017):
Microvascular Damage as Initial Event of Scar Formation after Carbon Ion Irradiation of Cardiac Substructures.
Darmstadt, Technische Universität,
[Ph.D. Thesis]


Friedel, Laura and Loewer, Alexander (2021):
The guardian's choice: How p53 enables context-specific decision making in individual cells.
In: The FEBS journal, ISSN 1742-4658,
DOI: 10.1111/febs.15767,

Friedrich, Dhana and Friedel, Laura and Finzel, Ana and Herrmann, Andreas and Preibisch, Stephan and Loewer, Alexander (2019):
Stochastic transcription in the p53-mediated response to DNA damage is modulated by burst frequency.
In: Molecular systems biology, 15 (12), pp. e9068. ISSN 1744-4292,
DOI: 10.15252/msb.20199068,

Friedrich, Dhana and Friedel, Laura and Finzel, Ana and Herrmann, Andreas and Preibisch, Stephan and Loewer, Alexander (2019):
Stochastic transcription in the p53‐mediated response to DNA damage is modulated by burst frequency.
In: Molecular Systems Biology, 15 (12), EMBOpress, e-ISSN 1744-4292,
DOI: 10.25534/tuprints-00011601,

Fang, Ge-Min and Chamiolo, Jasmine and Kankowski, Svenja and Hövelmann, Felix and Friedrich, Dhana and Loewer, Alexander and Meier, Jochen C. and Seitz, Oliver (2018):
A bright FIT-PNA hybridization probe for the hybridization state specific analysis of a C → U RNA edit via FRET in a binary system.
In: Chemical science, 9 (21), pp. 4794-4800. ISSN 2041-6520,

Finzel, Ana and Grybowski, Andrea and Strasen, Jette and Cristiano, Elena and Loewer, Alexander (2016):
Hyper-activation of ATM upon DNA-PKcs inhibition modulates p53 dynamics and cell fate in response to DNA damage.
In: Molecular biology of the cell, 27 (15), pp. 2360-2367. ISSN 1939-4586,


González, Erik and Rother, Marion and Kerr, Markus C. and Al-Zeer, Munir A. and Abu-Lubad, Mohammad and Kessler, Mirjana and Brinkmann, Volker and Loewer, Alexander and Meyer, Thomas F. (2014):
Chlamydia infection depends on a functional MDM2-p53 axis.
In: Nature communications, 5, p. 5201. ISSN 2041-1723,


Jentsch, Marcel (2020):
Computational Approaches to Examine Cellular Signalling Networks.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00011498,
[Ph.D. Thesis]

Jentsch, Marcel and Snyder, Petra and Sheng, Caibin and Cristiano, Elena and Loewer, Alexander (2020):
p53 dynamics in single cells are temperature-sensitive.
In: Scientific Reports, 10 (1), ISSN 2045-2322,
DOI: 10.25534/tuprints-00011576,


Konrath, Fabian and Mittermeier, Anna and Cristiano, Elena and Wolf, Jana and Loewer, Alexander (2020):
A systematic approach to decipher crosstalk in the p53 signaling pathway using single cell dynamics.
In: PLoS computational biology, 16 (6), pp. e1007901. ISSN 1553-7358,
DOI: 10.1371/journal.pcbi.1007901,

Karanam, Ketki and Loewer, Alexander and Lahav, Galit (2013):
Dynamics of the DNA damage response: insights from live-cell imaging.
In: Briefings in functional genomics, 12 (2), pp. 109-17. ISSN 2041-2657,

Karanam, Ketki and Kafri, Ran and Loewer, Alexander and Lahav, Galit (2012):
Quantitative live cell imaging reveals a gradual shift between DNA repair mechanisms and a maximal use of HR in mid S phase.
In: Molecular cell, 47 (2), pp. 320-9. ISSN 1097-4164,


Loewer, Alexander and Karanam, Ketki and Mock, Caroline and Lahav, Galit (2013):
The p53 response in single cells is linearly correlated to the number of DNA breaks without a distinct threshold.
In: BMC biology, 11, p. 114. ISSN 1741-7007,

Loewer, Alexander and Lahav, Galit (2011):
We are all individuals: causes and consequences of non-genetic heterogeneity in mammalian cells.
In: Current opinion in genetics & development, 21 (6), pp. 753-8. ISSN 1879-0380,

Loewer, Alexander and Batchelor, Eric and Gaglia, Giorgio and Lahav, Galit (2010):
Basal dynamics of p53 reveal transcriptionally attenuated pulses in cycling cells.
In: Cell, 142 (1), pp. 89-100. ISSN 1097-4172,

Loewer, Alexander and Lahav, Galit (2006):
Cellular conference call: external feedback affects cell-fate decisions.
In: Cell, 124 (6), pp. 1128-30. ISSN 0092-8674,

Loewer, Alexander and Soba, Peter and Beyreuther, Konrad and Paro, Renato and Merdes, Gunter (2004):
Cell-type-specific processing of the amyloid precursor protein by Presenilin during Drosophila development.
In: EMBO reports, 5 (4), pp. 405-11. ISSN 1469-221X,


Mönke, Gregor and Cristiano, Elena and Finzel, Ana and Friedrich, Dhana and Herzel, Hanspeter and Falcke, Martin and Loewer, Alexander (2017):
Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells.
In: Scientific Reports, 7, ISSN 2045-2322,
DOI: 10.1038/srep46571,

Memczak, Sebastian and Jens, Marvin and Elefsinioti, Antigoni and Torti, Francesca and Krueger, Janna and Rybak, Agnieszka and Maier, Luisa and Mackowiak, Sebastian D. and Gregersen, Lea H. and Munschauer, Mathias and Loewer, Alexander and Ziebold, Ulrike and Landthaler, Markus and Kocks, Christine and Le Noble, Ferdinand and Rajewsky, Nikolaus (2013):
Circular RNAs are a large class of animal RNAs with regulatory potency.
In: Nature, 495 (7441), pp. 333-8. ISSN 1476-4687,

Merdes, Gunter and Soba, Peter and Loewer, Alexander and Bilic, Michaela V. and Beyreuther, Konrad and Paro, Renato (2004):
Interference of human and Drosophila APP and APP-like proteins with PNS development in Drosophila.
In: The EMBO journal, 23 (20), pp. 4082-95. ISSN 0261-4189,


Orth, James D. and Loewer, Alexander and Lahav, Galit and Mitchison, Timothy J. (2012):
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction.
In: Molecular biology of the cell, 23 (4), pp. 567-76. ISSN 1939-4586,


Philippe, Grégoire J.-B. and Mittermeier, Anna and Lawrence, Nicole and Huang, Yen-Hua and Condon, Nicholas D. and Loewer, Alexander and Craik, David J. and Henriques, Sónia T. (2021):
Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells.
In: ACS chemical biology, 16 (2), pp. 414-428. ISSN 1554-8937,
DOI: 10.1021/acschembio.0c00988,

Patasic, Lea (2020):
DARPin-targeted Chimeric Antigen Receptor T cells: CD4 as a cellular target shows potential to evade HIV latency reservoir.
Darmstadt, Technische Universität,
DOI: 10.25534/tuprints-00013332,
[Ph.D. Thesis]

Philippe, Grégoire J.-B. and Gaspar, Diana and Sheng, Caibin and Huang, Yen-Hua and Benfield, Aurélie H. and Condon, Nicholas D. and Weidmann, Joachim and Lawrence, Nicole and Loewer, Alexander and Castanho, Miguel A. R. B. and Craik, David J. and Troeira Henriques, Sónia (2019):
Cell Membrane Composition Drives Selectivity and Toxicity of Designed Cyclic Helix–Loop–Helix Peptides with Cell Penetrating and Tumor Suppressor Properties.
In: ACS Chemical Biology, 14 (9), pp. 2071-2087. ISSN 1554-8929,
DOI: 10.1021/acschembio.9b00593,

Paek, Andrew L. and Liu, Julia C. and Loewer, Alexander and Forrester, William C. and Lahav, Galit (2016):
Cell-to-Cell Variation in p53 Dynamics Leads to Fractional Killing.
In: Cell, 165 (3), pp. 631-42. ISSN 1097-4172,

Purvis, Jeremy E. and Karhohs, Kyle W. and Mock, Caroline and Batchelor, Eric and Loewer, Alexander and Lahav, Galit (2012):
p53 dynamics control cell fate.
In: Science (New York, N.Y.), 336 (6087), pp. 1440-4. ISSN 1095-9203,

Peshkin, L. and Goni, J. and Loewer, Alexander and Kolluri, R. S. and Lahav, Galit and Wall, D. (2009):
Morphology from texture in cytometry.
In: IJTS, 16 (s10), pp. 41-55. [Article]


Rusu, Patricia and Jansen, Anna and Soba, Peter and Kirsch, Joachim and Loewer, Alexander and Merdes, Gunter and Kuan, Yung-Hui and Jung, Anita and Beyreuther, Konrad and Kjaerulff, Ole and Kins, Stefan (2007):
Axonal accumulation of synaptic markers in APP transgenic Drosophila depends on the NPTY motif and is paralleled by defects in synaptic plasticity.
In: The European journal of neuroscience, 25 (4), pp. 1079-86. ISSN 0953-816X,


Sheng, Caibin and Mendler, Isabella-Hilda and Rieke, Sara and Snyder, Petra and Jentsch, Marc and Friedrich, Dhana and Drossel, Barbara and Loewer, Alexander (2019):
PCNA-Mediated Degradation of p21 Coordinates the DNA Damage Response and Cell Cycle Regulation in Individual Cells.
In: Cell Reports, 27 (1), pp. 47-58.e7. DOI: 10.1016/j.celrep.2019.03.031,

Strasen, Jette and Sarma, Uddipan and Jentsch, Marcel and Bohn, Stefan and Sheng, Caibin and Horbelt, Daniel and Knaus, Petra and Legewie, Stefan and Loewer, Alexander (2018):
Cell-specific responses to the cytokine TGFβ are determined by variability in protein levels.
In: Molecular systems biology, 14 (1), pp. e7733. ISSN 1744-4292,

Schrenk-Siemens, Katrin and Wende, Hagen and Prato, Vincenzo and Song, Kun and Rostock, Charlotte and Loewer, Alexander and Utikal, Jochen and Lewin, Gary R. and Lechner, Stefan G. and Siemens, Jan (2015):
PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors.
In: Nature neuroscience, 18 (1), pp. 10-6. ISSN 1546-1726,

Schueler, Markus and Munschauer, Mathias and Gregersen, Lea Haarup and Finzel, Ana and Loewer, Alexander and Chen, Wei and Landthaler, Markus and Dieterich, Christoph (2014):
Differential protein occupancy profiling of the mRNA transcriptome.
In: Genome biology, 15 (1), pp. R15. ISSN 1474-760X,

Stempfle, Denise and Kanwar, Ritu and Loewer, Alexander and Fortini, Mark E. and Merdes, Gunter (2010):
In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.
In: Molecular and cellular biology, 30 (13), pp. 3165-75. ISSN 1098-5549,

Soba, Peter and Eggert, Simone and Wagner, Katja and Zentgraf, Hanswalter and Siehl, Katjuscha and Kreger, Sylvia and Loewer, Alexander and Langer, Andreas and Merdes, Gunter and Paro, Renato and Masters, Colin L. and Müller, Ulrike and Kins, Stefan and Beyreuther, Konrad (2006):
Cell interactions are promoted by transdimerization of APP family members, arranged as homo- or heterocomplexes in synaptic membranes.
In: The EMBO journal, 25 (3), p. 653. ISSN 0261-4189,


Toettcher, Jared E. and Mock, Caroline and Batchelor, Eric and Loewer, Alexander and Lahav, Galit (2010):
A synthetic-natural hybrid oscillator in human cells.
In: Proceedings of the National Academy of Sciences of the United States of America, 107 (39), pp. 17047-52. ISSN 1091-6490,

Toettcher, Jared E. and Loewer, Alexander and Ostheimer, Gerard J. and Yaffe, Michael B. and Tidor, Bruce and Lahav, Galit (2009):
Distinct mechanisms act in concert to mediate cell cycle arrest.
In: Proceedings of the National Academy of Sciences of the United States of America, 106 (3), pp. 785-90. ISSN 1091-6490,

This list was generated on Sun May 9 01:32:58 2021 CEST.