Artikel

Geissler, Marcus ; Neubauer, Christoph ; Sheludko, Yuriy V. ; Brückner, Adrian ; Warzecha, Heribert (2024)
Nepeta cataria L. (catnip) can serve as a chassis for the engineering of secondary metabolic pathways.
In: Biotechnology letters, 46 (5)
doi: 10.1007/s10529-024-03489-w
Artikel, Bibliographie

Juteršek, Mojca ; Gerasymenko, Iryna M. ; Petek, Marko ; Haumann, Elisabeth ; Vacas, Sandra ; Kallam, Kalyani ; Gianoglio, Silvia ; Navarro-Llopis, Vicente ; Heethoff, Michael ; Fuertes, Ismael Navarro ; Patron, Nicola ; Orzáez, Diego ; Gruden, Kristina ; Warzecha, Heribert ; Baebler, Špela (2024)
Transcriptome-informed identification and characterization of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes.
In: iScience, 27 (4)
doi: 10.1016/j.isci.2024.109441
Artikel, Bibliographie

Sator, Christian ; Lico, Chiara ; Pannucci, Elisa ; Marchetti, Luca ; Baschieri, Selene ; Warzecha, Heribert ; Santi, Luca (2024)
Plant-produced viral nanoparticles as a functionalized catalytic support for metabolic engineering.
In: Plants (Basel, Switzerland), 13 (4)
doi: 10.3390/plants13040503
Artikel, Bibliographie

Benvenuto, Eugenio ; Broer, Inge ; D'Aoust, Marc-André ; Hitzeroth, Inga ; Hundleby, Penny ; Menassa, Rima ; Oksman-Caldentey, Kirsi-Marja ; Peyret, Hadrien ; Salgueiro, Sancha ; Saxena, Pooja ; Stander, Jennifer ; Warzecha, Heribert ; Ma, Julian (2023)
Plant molecular farming in the wake of the closure of Medicago Inc.
In: Nature biotechnology, 41 (7)
doi: 10.1038/s41587-023-01812-w
Artikel, Bibliographie

Sheludko, Y. V. ; Gerasymenko, I. M. ; Herrmann, F. J. ; Warzecha, Heribert (2022)
Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6.
In: Transgenic research, 31 (3)
doi: 10.1007/s11248-022-00305-x
Artikel, Bibliographie

Gerasymenko, Iryna ; Sheludko, Yuriy V. ; Fuertes, Ismael Navarro ; Schmidts, Volker ; Steinel, Lara ; Haumann, Elisabeth ; Warzecha, Heribert (2022)
Engineering of a plant isoprenyl diphosphate synthase for development of irregular coupling activity.
In: Chembiochem : a European journal of chemical biology, 23 (1)
doi: 10.1002/cbic.202100465
Artikel, Bibliographie

Stanbekova, Gulshan ; Beisenov, Daniyar ; Nizkorodova, Anna ; Iskakov, Bulat ; Warzecha, Heribert (2021)
Production of the sheep pox virus structural protein SPPV117 in tobacco chloroplasts.
In: Biotechnology letters, 43 (7)
doi: 10.1007/s10529-021-03117-x
Artikel, Bibliographie

Stanbekova, Gulshan ; Beisenov, Daniyar ; Nizkorodova, Anna ; Iskakov, Bulat ; Warzecha, Heribert (2021)
Production of the sheep pox virus structural protein SPPV117 in tobacco chloroplasts.
In: Biotechnology Letters, 43 (7)
doi: 10.1007/s10529-021-03117-x
Artikel, Bibliographie

Sheludko, Yuriy ; Volk, Jascha ; Brandt, Wolfgang ; Warzecha, Heribert (2020)
Expanding the diversity of plant monoterpenoid indole alkaloids employing human cytochrome P450 3A4.
In: Chembiochem : a European journal of chemical biology
doi: 10.1002/cbic.202000020
Artikel, Bibliographie

Volk, Jascha ; Sarafeddinov, Alla ; Unver, Turgay ; Marx, Stefan ; Tretzel, Joachim ; Zotzel, Jens ; Warzecha, Heribert (2019)
Correction to: Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters.
In: Planta, 250 (6)
doi: 10.1007/s00425-019-03291-3
Artikel, Bibliographie

Volk, Jascha ; Sarafeddinov, Alla ; Unver, Turgay ; Marx, Stefan ; Tretzel, Joachim ; Zotzel, Jens ; Warzecha, Heribert (2019)
Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters.
In: Planta, 250 (6)
doi: 10.1007/s00425-019-03286-0
Artikel, Bibliographie

Gerasymenko, Iryna ; Sheludko, Yuriy ; Fräbel, Sabine ; Staniek, Agata ; Warzecha, Heribert (2019)
Combinatorial biosynthesis of small molecules in plants: Engineering strategies and tools.
In: Methods in enzymology, 617
Artikel, Bibliographie

Stanbekova, Gulshan ; Beisenov, Daniyar ; Nadirova, Leila ; Iskakov, Bulat ; Warzecha, Heribert (2018)
Recombinant sheep pox virus antigens expression in chloroplasts.
In: Journal of Biotechnology, 280
doi: 10.1016/j.jbiotec.2018.06.280
Artikel, Bibliographie

Geissler, Marcus ; Volk, Jascha ; Stehle, Felix ; Kayser, Oliver ; Warzecha, Heribert (2018)
Subcellular localization defines modification and production of Δ-tetrahydrocannabinolic acid synthase in transiently transformed Nicotiana benthamiana.
In: Biotechnology letters, 40 (6)
Artikel, Bibliographie

Sheludko, Yuriy V. ; Gerasymenko, Iryna M. ; Warzecha, Heribert (2018)
Transient expression of human cytochrome P450s 2D6 and 3A4 in Nicotiana benthamiana provides a possibility for rapid substrate testing and production of novel compounds.
In: Biotechnology journal, 13 (11)
Artikel, Bibliographie

Schachtsiek, Julia ; Warzecha, Heribert ; Kayser, Oliver ; Stehle, Felix (2018)
Current Perspectives on Biotechnological Cannabinoid Production in Plants.
In: Planta medica, 84 (4)
Artikel, Bibliographie

Fräbel, Sabine ; Wagner, Bastian ; Krischke, Markus ; Schmidts, Volker ; Thiele, Christina M. ; Staniek, Agata ; Warzecha, Heribert (2018)
Engineering of new-to-nature halogenated indigo precursors in plants.
In: Metabolic Engineering, 46
doi: 10.1016/j.ymben.2018.02.003
Artikel, Bibliographie

Geissler, Marcus ; Burghard, Marie ; Volk, Jascha ; Staniek, Agata ; Warzecha, Heribert (2016)
A novel cinnamyl alcohol dehydrogenase (CAD)-like reductase contributes to the structural diversity of monoterpenoid indole alkaloids in Rauvolfia.
In: Planta, 243 (3)
Artikel, Bibliographie

Topp, Edward ; Irwin, Rebecca ; McAllister, Tim ; Lessard, Martin ; Joensuu, Jussi J. ; Kolotilin, Igor ; Conrad, Udo ; Stöger, Eva ; Mor, Tsafrir ; Warzecha, Heribert ; Hall, J. Chris ; McLean, Michael D. ; Cox, Eric ; Devriendt, Bert ; Potter, Andrew ; Depicker, Ann ; Virdi, Vikram ; Holbrook, Larry ; Doshi, Ketan ; Dussault, Marike ; Friendship, Robert ; Yarosh, Oksana ; Yoo, Han Sang ; MacDonald, Jacqueline ; Menassa, Rima (2016)
The case for plant-made veterinary immunotherapeutics.
In: Biotechnology advances, 34 (5)
doi: 10.1016/j.biotechadv.2016.02.007
Artikel, Bibliographie

Warzecha, Heribert (2016)
Lights, P450, action! Metabolite formation in chloroplasts.
In: Journal of experimental botany, 67 (8)
Artikel, Bibliographie

Zahin, Maryam ; Joh, Joongho ; Khanal, Sujita ; Husk, Adam ; Mason, Hugh ; Warzecha, Heribert ; Ghim, Shin-Je ; Miller, Donald M. ; Matoba, Nobuyuki ; Jenson, Alfred Bennett (2016)
Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves.
In: PloS one, 11 (8)
Artikel, Bibliographie

Fräbel, Sabine ; Krischke, Markus ; Staniek, Agata ; Warzecha, Heribert (2016)
Recombinant flavin-dependent halogenases are functional in tobacco chloroplasts without co-expression of flavin reductase genes.
In: Biotechnology journal, 11 (12)
Artikel, Bibliographie

Xia, Liqun ; Lin, Haili ; Staniek, Agata ; Panjikar, Santosh ; Ruppert, Martin ; Hilgers, Petra ; Williardt, Jörg ; Rajendran, Chitra ; Wang, Meitian ; Warzecha, Heribert ; Jäger, Volker ; Stöckigt, Joachim (2015)
Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours.
In: Journal of enzyme inhibition and medicinal chemistry, 30 (3)
Artikel, Bibliographie

Patron, Nicola J. ; Orzaez, Diego ; Marillonnet, Sylvestre ; Warzecha, Heribert ; Matthewman, Colette ; Youles, Mark ; Raitskin, Oleg ; Leveau, Aymeric ; Farré, Gemma ; Rogers, Christian ; Smith, Alison ; Hibberd, Julian ; Webb, Alex A. R. ; Locke, James ; Schornack, Sebastian ; Ajioka, Jim ; Baulcombe, David C. ; Zipfel, Cyril ; Kamoun, Sophien ; Jones, Jonathan D. G. ; Kuhn, Hannah ; Robatzek, Silke ; Esse, H. Peter van ; Sanders, Dale ; Oldroyd, Giles ; Martin, Cathie ; Field, Rob ; O'Connor, Sarah ; Fox, Samantha ; Wulff, Brande ; Miller, Ben ; Breakspear, Andy ; Radhakrishnan, Guru ; Delaux, Pierre-Marc ; Loqué, Dominique ; Granell, Antonio ; Tissier, Alain ; Shih, Patrick ; Brutnell, Thomas P. ; Quick, W. Paul ; Rischer, Heiko ; Fraser, Paul D. ; Aharoni, Asaph ; Raines, Christine ; South, Paul F. ; Ané, Jean-Michel ; Hamberger, Björn R. ; Langdale, Jane ; Stougaard, Jens ; Bouwmeester, Harro ; Udvardi, Michael ; Murray, James A. H. ; Ntoukakis, Vardis ; Schäfer, Patrick ; Denby, Katherine ; Edwards, Keith J. ; Osbourn, Anne ; Haseloff, Jim (2015)
Standards for plant synthetic biology: a common syntax for exchange of DNA parts.
In: The New phytologist, 208 (1)
Artikel, Bibliographie

Martens, Stefan ; Hein, Sascha ; Beekwilder, Jules ; Hall, Robert ; Daran, Jean-Marc G. ; Warzecha, Heribert (2015)
Shame on yeast - challenges and bottlenecks to engineer red anthocyanin-producing yeasts.
In: Yeast, 32
Artikel, Bibliographie

Staniek, Agata ; Bouwmeester, Harro ; Fraser, Paul D. ; Kayser, Oliver ; Martens, Stefan ; Tissier, Alain ; Krol, Sander van der ; Wessjohann, Ludger ; Warzecha, Heribert (2014)
Natural products – learning chemistry from plants.
In: Biotechnology journal, 9 (3)
Artikel, Bibliographie

Vafaee, Yavar ; Staniek, Agata ; Mancheno-Solano, Maria ; Warzecha, Heribert (2014)
A Modular Cloning Toolbox for the Generation of Chloroplast Transformation Vectors.
In: PloS one, 9 (10)
Artikel, Bibliographie

Kolotilin, Igor ; Topp, Ed ; Cox, Eric ; Devriendt, Bert ; Conrad, Udo ; Joensuu, Jussi ; Stöger, Eva ; Warzecha, Heribert ; McAllister, Tim ; Potter, Andrew ; McLean, Michael D. ; Hall, J. Christopher ; Menassa, Rima (2014)
Plant-based solutions for veterinary immunotherapeutics and prophylactics.
In: Veterinary research, 45 (1)
Artikel, Bibliographie

Michoux, Franck ; Ahmad, Niaz ; Hennig, Anna ; Nixon, Peter J. ; Warzecha, Heribert (2013)
Production of leafy biomass using temporary immersion bioreactors: an alternative platform to express proteins in transplastomic plants with drastic phenotypes.
In: Planta, 237 (3)
Artikel, Bibliographie

Staniek, Agata ; Bouwmeester, Harro ; Fraser, Paul D. ; Kayser, Oliver ; Martens, Stefan ; Tissier, Alain ; Krol, Sander van der ; Wessjohann, Ludger ; Warzecha, Heribert (2013)
Natural products - modifying metabolite pathways in plants.
In: Biotechnology journal, 8 (10)
Artikel, Bibliographie

Panjikar, S. ; Stoeckigt, J. ; O'Connor, S. ; Warzecha, Heribert (2012)
The impact of structural biology on alkaloid biosynthesis research.
In: Natural product reports, 29 (10)
Artikel, Bibliographie

Pasquevich, K. A. ; Ibañez, A. E. ; Coria, L. M. ; García Samartino, C. ; Estein, S. M. ; Zwerdling, A. ; Barrionuevo, P. ; Oliveira, F. S. ; Seither, C. ; Warzecha, Heribert ; Oliveira, S. C. ; Giambartolomei, G. H. ; Cassataro, J. (2011)
An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
In: PloS one, 6 (1)
Artikel, Bibliographie

Warzecha, Heribert ; Ferme, D. ; Peer, M. ; Frank, A. ; Unger, M. (2010)
Bioconversion of the antihistaminc drug loratadine by tobacco cell suspension cultures expressing human cytochrome P450 3A4.
In: Journal of bioscience and bioengineering, 109 (3)
Artikel, Bibliographie

Pasquevich, K. A. ; García Samartino, C. ; Coria, L. M. ; Estein, S. M. ; Zwerdling, A. ; Ibañez, A. E. ; Barrionuevo, P. ; Oliveira, F. S. ; Carvalho, N. B. ; Borkowski, J. ; Oliveira, S. C. ; Warzecha, Heribert ; Giambartolomei, G. H. ; Cassataro, J. (2010)
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
In: Journal of immunology (Baltimore, Md. : 1950), 184 (9)
Artikel, Bibliographie

Sun, L. ; Ruppert, M. ; Sheludko, Y. ; Warzecha, Heribert ; Zhao, Y. ; Stöckigt, J. (2008)
Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia.
In: Plant molecular biology, 67 (5)
Artikel, Bibliographie

Reichwein, S. ; Warzecha, Heribert (2008)
Non-Hodgkin's lymphoma: personalized therapy with plants.
In: Pharmazie in unserer Zeit, 37 (6)
Artikel, Bibliographie

Hennig, A. ; Reinders, Y. ; Giritch, A. ; Reinders, J. ; Warzecha, Heribert (2008)
Assessment of different expression strategies for the production of a recombinant lipoprotein vaccine in plants.
In: Open Biotech. J., 2
Artikel, Bibliographie

Hennig, A. ; Bonfig, K. ; Roitsch, T. ; Warzecha, Heribert (2007)
Expression of the recombinant bacterial outer surface protein A in tobacco chloroplasts leads to thylakoid localization and loss of photosynthesis.
In: The FEBS journal, 274 (21)
Artikel, Bibliographie

Warzecha, Heribert ; Frank, A. ; Peer, M. ; Gillam, E. M. J. ; Guengerich, F. P. ; Unger, M. (2007)
Formation of the indigo precursor indican in genetically engineered tobacco plants and cell cultures.
In: Plant biotechnology journal, 5 (1)
Artikel, Bibliographie

Warzecha, Heribert (2007)
Die schwierige Suche nach geeignetem Blutersatz.
In: Deutsche Apothekerzeitung, (36)
Artikel, Bibliographie

Warzecha, Heribert (2007)
Lyme-Borreliose.
In: Deutsche Apothekerzeitung, (9)
Artikel, Bibliographie

Glenz, K. ; Bouchon, B. ; Stehle, T. ; Wallich, R. ; Simon, M. M. ; Warzecha, Heribert (2006)
Production of a recombinant bacterial lipoprotein in higher plant chloroplasts.
In: Nature biotechnology, 24 (1)
Artikel, Bibliographie

Glenz, K. ; Warzecha, Heribert (2006)
New medicinal plants for the production of vaccines.
In: J. Verbr. Lebensm. Supp., (1)
Artikel, Bibliographie

Dueckershoff, K. ; Unger, M. ; Frank, A. ; Gillam, E. M. J. ; Guengerich, F. P. ; Warzecha, Heribert (2005)
Modified nicotine metabolism in transgenic tobacco plants expressing the human cytochrome P450 2A6 cDNA.
In: FEBS letters, 579 (11)
Artikel, Bibliographie

Stuhlfelder, C. ; Mueller, M. J. ; Warzecha, Heribert (2004)
Cloning and expression of a tomato cDNA encoding a methyl jasmonate cleaving esterase.
In: European journal of biochemistry / FEBS, 271 (14)
Artikel, Bibliographie

Warzecha, Heribert ; Mason, H. S. ; Lane, C. ; Tryggvesson, A. ; Rybicki, E. ; Williamson, A.-L. ; Clements, J. D. ; Rose, R. C. (2003)
Oral immunogenicity of human papillomavirus-like particles expressed in potato.
In: Journal of virology, 77 (16)
Artikel, Bibliographie

Warzecha, Heribert ; Mason, H. S. (2003)
Benefits and risks of antibody and vaccine production in transgenic plants.
In: Journal of plant physiology, 160 (7)
Artikel, Bibliographie

Mason, H. S. ; Warzecha, Heribert ; Mor, T. ; Arntzen, C. J. (2002)
Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine.
In: Trends in molecular medicine, 8 (7)
Artikel, Bibliographie

Stöckigt, J. ; Sheludko, Y. ; Unger, M. ; Gerasimenko, I. ; Warzecha, Heribert ; Stöckigt, D. (2002)
High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups.
In: Journal of chromatography. A, 967 (1)
Artikel, Bibliographie

Hefner, T. ; Arend, J. ; Warzecha, Heribert ; Siems, K. ; Stöckigt, J. (2002)
Arbutin synthase, a novel member of the NRD1beta glycosyltransferase family, is a unique multifunctional enzyme converting various natural products and xenobiotics.
In: Bioorganic & medicinal chemistry, 10 (6)
Artikel, Bibliographie

Arend, J. ; Warzecha, Heribert ; Hefner, T. ; Stöckigt, J. (2001)
Utilizing genetically engineered bacteria to produce plant-specific glucosides.
In: Biotechnology and bioengineering, 76 (2)
Artikel, Bibliographie

Warzecha, Heribert (2001)
Neue Arzneipflanzen.
In: Zeitschrift für Phytotherapie, (4)
Artikel, Bibliographie

Warzecha, Heribert ; Gerasimenko, I. ; Kutchan, T. M. ; Stöckigt, J. (2000)
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis.
In: Phytochemistry, 54 (7)
Artikel, Bibliographie

Dogru, E. ; Warzecha, Heribert ; Seibel, F. ; Haebel, S. ; Lottspeich, F. ; Stöckigt, J. (2000)
The gene encoding polyneuridine aldehyde esterase of monoterpenoid indole alkaloid biosynthesis in plants is an ortholog of the alpha/betahydrolase super family.
In: European journal of biochemistry / FEBS, 267 (5)
Artikel, Bibliographie

Arend, J. ; Warzecha, Heribert ; Stöckigt, J. (2000)
Hydroquinone: O-glucosyltransferase from cultivated Rauvolfia cells: enrichment and partial amino acid sequences.
In: Phytochemistry, 53 (2)
Artikel, Bibliographie

Warzecha, Heribert (2000)
Essbare Impfstoffe.
In: Deutsche Apothekerzeitung, (31)
Artikel, Bibliographie

Warzecha, Heribert ; Obitz, P. ; Stöckigt, J. (1999)
Purification, partial amino acid sequence and structure of the product of raucaffricine-O-beta-D-glucosidase from plant cell cultures of Rauwolfia serpentina.
In: Phytochemistry, 50 (7)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Incredible edible veggie vaccines.
In: Sabin Vaccine Report, 3 (2)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Interaktionen von Arzneimitteln und Grapefruitsaft.
In: Deutsche Apothekerzeitung, (19)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Neue Möglichkeiten bei der Suche nach Wirkstoffen.
In: Deutsche Apothekerzeitung, (2)
Artikel, Bibliographie

Warzecha, Heribert (1998)
Biotransformation N-haltiger funktioneller Gruppen in Arznei- und Wirkstoffen.
In: Deutsche Apothekerzeitung, (50)
Artikel, Bibliographie

Buchkapitel

Hennig, A. ; Warzecha, Heribert
Hrsg.: Kempken, F. (2010)
Plastid transformation.
In: Genetic modification of plants - agriculture, horticulture and forestry
Buchkapitel, Bibliographie

Reichwein, S. ; Warzecha, Heribert
Hrsg.: Arora, R. (2010)
Novel medicinal plants for the production and delivery of vaccines.
In: Medicinal plant biotechnology
Buchkapitel, Bibliographie

Warzecha, Heribert (2008)
Biopharmaceuticals from plants : a multitude of options for posttranslational modifications.
In: Biotechnology and Genetic Engineering Reviews
Buchkapitel, Bibliographie

Konferenzveröffentlichung

Warzecha, Heribert ; Stöckigt, J.
Hrsg.: Zongmu, W. (1998)
New enzymes of indole alkaloid biosynthesis.
3rd Symposium of Frontiers in Protein Chemistry and Biotechnology. Changchun, P.R. China
Konferenzveröffentlichung, Bibliographie

Dissertation

Lin, Yen-Ju (2022)
Immunological characterization of Man2 as a novel adjuvant and rFlaA:Betv1 as a therapeutic candidate for allergy treatment.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00022284
Dissertation, Erstveröffentlichung, Verlagsversion

Geißler, Marcus Frank (2021)
Metabolic engineering of cannabinoid biosynthesis in tobacco.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00019075
Dissertation, Erstveröffentlichung, Verlagsversion

Volk, Jascha (2019)
Identification and characterization of esterases involved in the conversion of oleosides in Olea europaea.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Pennekamp, Henning (2015)
Alternative Strategien gegen Malaria mit Hilfe transgener Pflanzen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Reichwein, Simone (2013)
Expression und Analyse plasmodialer und antiplasmodialer Proteine in Pflanzen.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

Forschungsdaten

Fräbel, Sabine (2016)
Characterization of flavin-dependent tryptophan halogenases and their application in plant metabolic engineering.
Forschungsdaten, Erstveröffentlichung