Geissler, Marcus ; Neubauer, Christoph ; Sheludko, Yuriy V. ; Brückner, Adrian ; Warzecha, Heribert (2024)
Nepeta cataria L. (catnip) can serve as a chassis for the engineering of secondary metabolic pathways.
In: Biotechnology letters, 46 (5)
doi: 10.1007/s10529-024-03489-w
Artikel, Bibliographie

Juteršek, Mojca ; Gerasymenko, Iryna M. ; Petek, Marko ; Haumann, Elisabeth ; Vacas, Sandra ; Kallam, Kalyani ; Gianoglio, Silvia ; Navarro-Llopis, Vicente ; Heethoff, Michael ; Fuertes, Ismael Navarro ; Patron, Nicola ; Orzáez, Diego ; Gruden, Kristina ; Warzecha, Heribert ; Baebler, Špela (2024)
Transcriptome-informed identification and characterization of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes.
In: iScience, 27 (4)
doi: 10.1016/j.isci.2024.109441
Artikel, Bibliographie

Sator, Christian ; Lico, Chiara ; Pannucci, Elisa ; Marchetti, Luca ; Baschieri, Selene ; Warzecha, Heribert ; Santi, Luca (2024)
Plant-produced viral nanoparticles as a functionalized catalytic support for metabolic engineering.
In: Plants (Basel, Switzerland), 13 (4)
doi: 10.3390/plants13040503
Artikel, Bibliographie

Benvenuto, Eugenio ; Broer, Inge ; D'Aoust, Marc-André ; Hitzeroth, Inga ; Hundleby, Penny ; Menassa, Rima ; Oksman-Caldentey, Kirsi-Marja ; Peyret, Hadrien ; Salgueiro, Sancha ; Saxena, Pooja ; Stander, Jennifer ; Warzecha, Heribert ; Ma, Julian (2023)
Plant molecular farming in the wake of the closure of Medicago Inc.
In: Nature biotechnology, 41 (7)
doi: 10.1038/s41587-023-01812-w
Artikel, Bibliographie

Sheludko, Y. V. ; Gerasymenko, I. M. ; Herrmann, F. J. ; Warzecha, Heribert (2022)
Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6.
In: Transgenic research, 31 (3)
doi: 10.1007/s11248-022-00305-x
Artikel, Bibliographie

Gerasymenko, Iryna ; Sheludko, Yuriy V. ; Fuertes, Ismael Navarro ; Schmidts, Volker ; Steinel, Lara ; Haumann, Elisabeth ; Warzecha, Heribert (2022)
Engineering of a plant isoprenyl diphosphate synthase for development of irregular coupling activity.
In: Chembiochem : a European journal of chemical biology, 23 (1)
doi: 10.1002/cbic.202100465
Artikel, Bibliographie

Stanbekova, Gulshan ; Beisenov, Daniyar ; Nizkorodova, Anna ; Iskakov, Bulat ; Warzecha, Heribert (2021)
Production of the sheep pox virus structural protein SPPV117 in tobacco chloroplasts.
In: Biotechnology letters, 43 (7)
doi: 10.1007/s10529-021-03117-x
Artikel, Bibliographie

Sheludko, Yuriy ; Volk, Jascha ; Brandt, Wolfgang ; Warzecha, Heribert (2020)
Expanding the diversity of plant monoterpenoid indole alkaloids employing human cytochrome P450 3A4.
In: Chembiochem : a European journal of chemical biology
doi: 10.1002/cbic.202000020
Artikel, Bibliographie

Volk, Jascha ; Sarafeddinov, Alla ; Unver, Turgay ; Marx, Stefan ; Tretzel, Joachim ; Zotzel, Jens ; Warzecha, Heribert (2019)
Correction to: Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters.
In: Planta, 250 (6)
doi: 10.1007/s00425-019-03291-3
Artikel, Bibliographie

Volk, Jascha ; Sarafeddinov, Alla ; Unver, Turgay ; Marx, Stefan ; Tretzel, Joachim ; Zotzel, Jens ; Warzecha, Heribert (2019)
Two novel methylesterases from Olea europaea contribute to the catabolism of oleoside-type secoiridoid esters.
In: Planta, 250 (6)
doi: 10.1007/s00425-019-03286-0
Artikel, Bibliographie

Gerasymenko, Iryna ; Sheludko, Yuriy ; Fräbel, Sabine ; Staniek, Agata ; Warzecha, Heribert (2019)
Combinatorial biosynthesis of small molecules in plants: Engineering strategies and tools.
In: Methods in enzymology, 617
Artikel, Bibliographie

Stanbekova, Gulshan ; Beisenov, Daniyar ; Nadirova, Leila ; Iskakov, Bulat ; Warzecha, Heribert (2018)
Recombinant sheep pox virus antigens expression in chloroplasts.
In: Journal of Biotechnology, 280
doi: 10.1016/j.jbiotec.2018.06.280
Artikel, Bibliographie

Geissler, Marcus ; Volk, Jascha ; Stehle, Felix ; Kayser, Oliver ; Warzecha, Heribert (2018)
Subcellular localization defines modification and production of Δ-tetrahydrocannabinolic acid synthase in transiently transformed Nicotiana benthamiana.
In: Biotechnology letters, 40 (6)
Artikel, Bibliographie

Sheludko, Yuriy V. ; Gerasymenko, Iryna M. ; Warzecha, Heribert (2018)
Transient expression of human cytochrome P450s 2D6 and 3A4 in Nicotiana benthamiana provides a possibility for rapid substrate testing and production of novel compounds.
In: Biotechnology journal, 13 (11)
Artikel, Bibliographie

Schachtsiek, Julia ; Warzecha, Heribert ; Kayser, Oliver ; Stehle, Felix (2018)
Current Perspectives on Biotechnological Cannabinoid Production in Plants.
In: Planta medica, 84 (4)
Artikel, Bibliographie

Fräbel, Sabine ; Wagner, Bastian ; Krischke, Markus ; Schmidts, Volker ; Thiele, Christina M. ; Staniek, Agata ; Warzecha, Heribert (2018)
Engineering of new-to-nature halogenated indigo precursors in plants.
In: Metabolic Engineering, 46
doi: 10.1016/j.ymben.2018.02.003
Artikel, Bibliographie

Warzecha, Heribert (2016)
Lights, P450, action! Metabolite formation in chloroplasts.
In: Journal of experimental botany, 67 (8)
Artikel, Bibliographie

Fräbel, Sabine ; Krischke, Markus ; Staniek, Agata ; Warzecha, Heribert (2016)
Recombinant flavin-dependent halogenases are functional in tobacco chloroplasts without co-expression of flavin reductase genes.
In: Biotechnology journal, 11 (12)
Artikel, Bibliographie

Zahin, Maryam ; Joh, Joongho ; Khanal, Sujita ; Husk, Adam ; Mason, Hugh ; Warzecha, Heribert ; Ghim, Shin-Je ; Miller, Donald M. ; Matoba, Nobuyuki ; Jenson, Alfred Bennett (2016)
Scalable Production of HPV16 L1 Protein and VLPs from Tobacco Leaves.
In: PloS one, 11 (8)
Artikel, Bibliographie

Topp, Edward ; Irwin, Rebecca ; McAllister, Tim ; Lessard, Martin ; Joensuu, Jussi J. ; Kolotilin, Igor ; Conrad, Udo ; Stöger, Eva ; Mor, Tsafrir ; Warzecha, Heribert ; Hall, J. Chris ; McLean, Michael D. ; Cox, Eric ; Devriendt, Bert ; Potter, Andrew ; Depicker, Ann ; Virdi, Vikram ; Holbrook, Larry ; Doshi, Ketan ; Dussault, Marike ; Friendship, Robert ; Yarosh, Oksana ; Yoo, Han Sang ; MacDonald, Jacqueline ; Menassa, Rima (2016)
The case for plant-made veterinary immunotherapeutics.
In: Biotechnology advances, 34 (5)
doi: 10.1016/j.biotechadv.2016.02.007
Artikel, Bibliographie

Geissler, Marcus ; Burghard, Marie ; Volk, Jascha ; Staniek, Agata ; Warzecha, Heribert (2016)
A novel cinnamyl alcohol dehydrogenase (CAD)-like reductase contributes to the structural diversity of monoterpenoid indole alkaloids in Rauvolfia.
In: Planta, 243 (3)
Artikel, Bibliographie

Xia, Liqun ; Lin, Haili ; Staniek, Agata ; Panjikar, Santosh ; Ruppert, Martin ; Hilgers, Petra ; Williardt, Jörg ; Rajendran, Chitra ; Wang, Meitian ; Warzecha, Heribert ; Jäger, Volker ; Stöckigt, Joachim (2015)
Ligand structures of synthetic deoxa-pyranosylamines with raucaffricine and strictosidine glucosidases provide structural insights into their binding and inhibitory behaviours.
In: Journal of enzyme inhibition and medicinal chemistry, 30 (3)
Artikel, Bibliographie

Martens, Stefan ; Hein, Sascha ; Beekwilder, Jules ; Hall, Robert ; Daran, Jean-Marc G. ; Warzecha, Heribert (2015)
Shame on yeast - challenges and bottlenecks to engineer red anthocyanin-producing yeasts.
In: Yeast, 32
Artikel, Bibliographie

Patron, Nicola J. ; Orzaez, Diego ; Marillonnet, Sylvestre ; Warzecha, Heribert ; Matthewman, Colette ; Youles, Mark ; Raitskin, Oleg ; Leveau, Aymeric ; Farré, Gemma ; Rogers, Christian ; Smith, Alison ; Hibberd, Julian ; Webb, Alex A. R. ; Locke, James ; Schornack, Sebastian ; Ajioka, Jim ; Baulcombe, David C. ; Zipfel, Cyril ; Kamoun, Sophien ; Jones, Jonathan D. G. ; Kuhn, Hannah ; Robatzek, Silke ; Esse, H. Peter van ; Sanders, Dale ; Oldroyd, Giles ; Martin, Cathie ; Field, Rob ; O'Connor, Sarah ; Fox, Samantha ; Wulff, Brande ; Miller, Ben ; Breakspear, Andy ; Radhakrishnan, Guru ; Delaux, Pierre-Marc ; Loqué, Dominique ; Granell, Antonio ; Tissier, Alain ; Shih, Patrick ; Brutnell, Thomas P. ; Quick, W. Paul ; Rischer, Heiko ; Fraser, Paul D. ; Aharoni, Asaph ; Raines, Christine ; South, Paul F. ; Ané, Jean-Michel ; Hamberger, Björn R. ; Langdale, Jane ; Stougaard, Jens ; Bouwmeester, Harro ; Udvardi, Michael ; Murray, James A. H. ; Ntoukakis, Vardis ; Schäfer, Patrick ; Denby, Katherine ; Edwards, Keith J. ; Osbourn, Anne ; Haseloff, Jim (2015)
Standards for plant synthetic biology: a common syntax for exchange of DNA parts.
In: The New phytologist, 208 (1)
Artikel, Bibliographie

Vafaee, Yavar ; Staniek, Agata ; Mancheno-Solano, Maria ; Warzecha, Heribert (2014)
A Modular Cloning Toolbox for the Generation of Chloroplast Transformation Vectors.
In: PloS one, 9 (10)
Artikel, Bibliographie

Staniek, Agata ; Bouwmeester, Harro ; Fraser, Paul D. ; Kayser, Oliver ; Martens, Stefan ; Tissier, Alain ; Krol, Sander van der ; Wessjohann, Ludger ; Warzecha, Heribert (2014)
Natural products – learning chemistry from plants.
In: Biotechnology journal, 9 (3)
Artikel, Bibliographie

Kolotilin, Igor ; Topp, Ed ; Cox, Eric ; Devriendt, Bert ; Conrad, Udo ; Joensuu, Jussi ; Stöger, Eva ; Warzecha, Heribert ; McAllister, Tim ; Potter, Andrew ; McLean, Michael D. ; Hall, J. Christopher ; Menassa, Rima (2014)
Plant-based solutions for veterinary immunotherapeutics and prophylactics.
In: Veterinary research, 45 (1)
Artikel, Bibliographie

Staniek, Agata ; Bouwmeester, Harro ; Fraser, Paul D. ; Kayser, Oliver ; Martens, Stefan ; Tissier, Alain ; Krol, Sander van der ; Wessjohann, Ludger ; Warzecha, Heribert (2013)
Natural products - modifying metabolite pathways in plants.
In: Biotechnology journal, 8 (10)
Artikel, Bibliographie

Michoux, Franck ; Ahmad, Niaz ; Hennig, Anna ; Nixon, Peter J. ; Warzecha, Heribert (2013)
Production of leafy biomass using temporary immersion bioreactors: an alternative platform to express proteins in transplastomic plants with drastic phenotypes.
In: Planta, 237 (3)
Artikel, Bibliographie

Panjikar, S. ; Stoeckigt, J. ; O'Connor, S. ; Warzecha, Heribert (2012)
The impact of structural biology on alkaloid biosynthesis research.
In: Natural product reports, 29 (10)
Artikel, Bibliographie

Pasquevich, K. A. ; Ibañez, A. E. ; Coria, L. M. ; García Samartino, C. ; Estein, S. M. ; Zwerdling, A. ; Barrionuevo, P. ; Oliveira, F. S. ; Seither, C. ; Warzecha, Heribert ; Oliveira, S. C. ; Giambartolomei, G. H. ; Cassataro, J. (2011)
An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
In: PloS one, 6 (1)
Artikel, Bibliographie

Warzecha, Heribert ; Ferme, D. ; Peer, M. ; Frank, A. ; Unger, M. (2010)
Bioconversion of the antihistaminc drug loratadine by tobacco cell suspension cultures expressing human cytochrome P450 3A4.
In: Journal of bioscience and bioengineering, 109 (3)
Artikel, Bibliographie

Reichwein, S. ; Warzecha, Heribert
Hrsg.: Arora, R. (2010)
Novel medicinal plants for the production and delivery of vaccines.
In: Medicinal plant biotechnology
Buchkapitel, Bibliographie

Hennig, A. ; Warzecha, Heribert
Hrsg.: Kempken, F. (2010)
Plastid transformation.
In: Genetic modification of plants - agriculture, horticulture and forestry
Buchkapitel, Bibliographie

Pasquevich, K. A. ; García Samartino, C. ; Coria, L. M. ; Estein, S. M. ; Zwerdling, A. ; Ibañez, A. E. ; Barrionuevo, P. ; Oliveira, F. S. ; Carvalho, N. B. ; Borkowski, J. ; Oliveira, S. C. ; Warzecha, Heribert ; Giambartolomei, G. H. ; Cassataro, J. (2010)
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
In: Journal of immunology (Baltimore, Md. : 1950), 184 (9)
Artikel, Bibliographie

Hennig, A. ; Reinders, Y. ; Giritch, A. ; Reinders, J. ; Warzecha, Heribert (2008)
Assessment of different expression strategies for the production of a recombinant lipoprotein vaccine in plants.
In: Open Biotech. J., 2
Artikel, Bibliographie

Warzecha, Heribert (2008)
Biopharmaceuticals from plants : a multitude of options for posttranslational modifications.
In: Biotechnology and Genetic Engineering Reviews
Buchkapitel, Bibliographie

Reichwein, S. ; Warzecha, Heribert (2008)
Non-Hodgkin's lymphoma: personalized therapy with plants.
In: Pharmazie in unserer Zeit, 37 (6)
Artikel, Bibliographie

Sun, L. ; Ruppert, M. ; Sheludko, Y. ; Warzecha, Heribert ; Zhao, Y. ; Stöckigt, J. (2008)
Purification, cloning, functional expression and characterization of perakine reductase: the first example from the AKR enzyme family, extending the alkaloidal network of the plant Rauvolfia.
In: Plant molecular biology, 67 (5)
Artikel, Bibliographie

Warzecha, Heribert (2007)
Die schwierige Suche nach geeignetem Blutersatz.
In: Deutsche Apothekerzeitung, (36)
Artikel, Bibliographie

Hennig, A. ; Bonfig, K. ; Roitsch, T. ; Warzecha, Heribert (2007)
Expression of the recombinant bacterial outer surface protein A in tobacco chloroplasts leads to thylakoid localization and loss of photosynthesis.
In: The FEBS journal, 274 (21)
Artikel, Bibliographie

Warzecha, Heribert ; Frank, A. ; Peer, M. ; Gillam, E. M. J. ; Guengerich, F. P. ; Unger, M. (2007)
Formation of the indigo precursor indican in genetically engineered tobacco plants and cell cultures.
In: Plant biotechnology journal, 5 (1)
Artikel, Bibliographie

Warzecha, Heribert (2007)
Lyme-Borreliose.
In: Deutsche Apothekerzeitung, (9)
Artikel, Bibliographie

Glenz, K. ; Warzecha, Heribert (2006)
New medicinal plants for the production of vaccines.
In: J. Verbr. Lebensm. Supp., (1)
Artikel, Bibliographie

Glenz, K. ; Bouchon, B. ; Stehle, T. ; Wallich, R. ; Simon, M. M. ; Warzecha, Heribert (2006)
Production of a recombinant bacterial lipoprotein in higher plant chloroplasts.
In: Nature biotechnology, 24 (1)
Artikel, Bibliographie

Dueckershoff, K. ; Unger, M. ; Frank, A. ; Gillam, E. M. J. ; Guengerich, F. P. ; Warzecha, Heribert (2005)
Modified nicotine metabolism in transgenic tobacco plants expressing the human cytochrome P450 2A6 cDNA.
In: FEBS letters, 579 (11)
Artikel, Bibliographie

Stuhlfelder, C. ; Mueller, M. J. ; Warzecha, Heribert (2004)
Cloning and expression of a tomato cDNA encoding a methyl jasmonate cleaving esterase.
In: European journal of biochemistry / FEBS, 271 (14)
Artikel, Bibliographie

Warzecha, Heribert ; Mason, H. S. (2003)
Benefits and risks of antibody and vaccine production in transgenic plants.
In: Journal of plant physiology, 160 (7)
Artikel, Bibliographie

Warzecha, Heribert ; Mason, H. S. ; Lane, C. ; Tryggvesson, A. ; Rybicki, E. ; Williamson, A.-L. ; Clements, J. D. ; Rose, R. C. (2003)
Oral immunogenicity of human papillomavirus-like particles expressed in potato.
In: Journal of virology, 77 (16)
Artikel, Bibliographie

Hefner, T. ; Arend, J. ; Warzecha, Heribert ; Siems, K. ; Stöckigt, J. (2002)
Arbutin synthase, a novel member of the NRD1beta glycosyltransferase family, is a unique multifunctional enzyme converting various natural products and xenobiotics.
In: Bioorganic & medicinal chemistry, 10 (6)
Artikel, Bibliographie

Mason, H. S. ; Warzecha, Heribert ; Mor, T. ; Arntzen, C. J. (2002)
Edible plant vaccines: applications for prophylactic and therapeutic molecular medicine.
In: Trends in molecular medicine, 8 (7)
Artikel, Bibliographie

Stöckigt, J. ; Sheludko, Y. ; Unger, M. ; Gerasimenko, I. ; Warzecha, Heribert ; Stöckigt, D. (2002)
High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups.
In: Journal of chromatography. A, 967 (1)
Artikel, Bibliographie

Warzecha, Heribert (2001)
Neue Arzneipflanzen.
In: Zeitschrift für Phytotherapie, (4)
Artikel, Bibliographie

Arend, J. ; Warzecha, Heribert ; Hefner, T. ; Stöckigt, J. (2001)
Utilizing genetically engineered bacteria to produce plant-specific glucosides.
In: Biotechnology and bioengineering, 76 (2)
Artikel, Bibliographie

Warzecha, Heribert (2000)
Essbare Impfstoffe.
In: Deutsche Apothekerzeitung, (31)
Artikel, Bibliographie

Arend, J. ; Warzecha, Heribert ; Stöckigt, J. (2000)
Hydroquinone: O-glucosyltransferase from cultivated Rauvolfia cells: enrichment and partial amino acid sequences.
In: Phytochemistry, 53 (2)
Artikel, Bibliographie

Warzecha, Heribert ; Gerasimenko, I. ; Kutchan, T. M. ; Stöckigt, J. (2000)
Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis.
In: Phytochemistry, 54 (7)
Artikel, Bibliographie

Dogru, E. ; Warzecha, Heribert ; Seibel, F. ; Haebel, S. ; Lottspeich, F. ; Stöckigt, J. (2000)
The gene encoding polyneuridine aldehyde esterase of monoterpenoid indole alkaloid biosynthesis in plants is an ortholog of the alpha/betahydrolase super family.
In: European journal of biochemistry / FEBS, 267 (5)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Incredible edible veggie vaccines.
In: Sabin Vaccine Report, 3 (2)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Interaktionen von Arzneimitteln und Grapefruitsaft.
In: Deutsche Apothekerzeitung, (19)
Artikel, Bibliographie

Warzecha, Heribert (1999)
Neue Möglichkeiten bei der Suche nach Wirkstoffen.
In: Deutsche Apothekerzeitung, (2)
Artikel, Bibliographie

Warzecha, Heribert ; Obitz, P. ; Stöckigt, J. (1999)
Purification, partial amino acid sequence and structure of the product of raucaffricine-O-beta-D-glucosidase from plant cell cultures of Rauwolfia serpentina.
In: Phytochemistry, 50 (7)
Artikel, Bibliographie

Warzecha, Heribert (1998)
Biotransformation N-haltiger funktioneller Gruppen in Arznei- und Wirkstoffen.
In: Deutsche Apothekerzeitung, (50)
Artikel, Bibliographie

Warzecha, Heribert ; Stöckigt, J.
Hrsg.: Zongmu, W. (1998)
New enzymes of indole alkaloid biosynthesis.
3rd Symposium of Frontiers in Protein Chemistry and Biotechnology. Changchun, P.R. China
Konferenzveröffentlichung, Bibliographie