Schachtsiek, Julia ; Warzecha, Heribert ; Kayser, Oliver ; Stehle, Felix (2018)
Current Perspectives on Biotechnological Cannabinoid Production in Plants.
In: Planta medica, 84 (4)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
The plant Cannabis sativa contains a number of psychoactive chemical compounds, the cannabinoids, which possess a significant pharmaceutical potential. Recently, the usage of Cannabis for medicinal purposes was legalized in many countries. Thus, the study on the influence of different cannabinoids in combination with other Cannabis-derived compounds with respect to the treatment of various diseases becomes increasingly important. Besides the production of distinct cannabinoids in a heterologous host, like tobacco or yeast, transgenic Cannabis plants would be a suitable alternative to modify and therefore optimize the cannabinoid profile. This perspective highlights the current efforts on Cannabis cell culture systems, in vitro propagation, and transformation of the plant and reveals the resulting opportunities concerning biotechnological production of cannabinoids. Furthermore, alternative platform organisms for the heterologous production of cannabinoids, like tobacco, are considered and evaluated.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2018 |
| Autor(en): | Schachtsiek, Julia ; Warzecha, Heribert ; Kayser, Oliver ; Stehle, Felix |
| Art des Eintrags: | Bibliographie |
| Titel: | Current Perspectives on Biotechnological Cannabinoid Production in Plants. |
| Sprache: | Englisch |
| Publikationsjahr: | März 2018 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Planta medica |
| Jahrgang/Volume einer Zeitschrift: | 84 |
| (Heft-)Nummer: | 4 |
| Kurzbeschreibung (Abstract): | The plant Cannabis sativa contains a number of psychoactive chemical compounds, the cannabinoids, which possess a significant pharmaceutical potential. Recently, the usage of Cannabis for medicinal purposes was legalized in many countries. Thus, the study on the influence of different cannabinoids in combination with other Cannabis-derived compounds with respect to the treatment of various diseases becomes increasingly important. Besides the production of distinct cannabinoids in a heterologous host, like tobacco or yeast, transgenic Cannabis plants would be a suitable alternative to modify and therefore optimize the cannabinoid profile. This perspective highlights the current efforts on Cannabis cell culture systems, in vitro propagation, and transformation of the plant and reveals the resulting opportunities concerning biotechnological production of cannabinoids. Furthermore, alternative platform organisms for the heterologous production of cannabinoids, like tobacco, are considered and evaluated. |
| ID-Nummer: | pmid:29301148 |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Plant Biotechnology and Metabolic Engineering |
| Hinterlegungsdatum: | 09 Jan 2018 09:29 |
| Letzte Änderung: | 15 Mär 2018 07:46 |
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