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Anzahl der Einträge: 81.

Kruse, Elisabeth ; Göringer, H. Ulrich (2023)
Nanopore-based direct RNA sequencing of the Trypanosoma brucei transcriptome identifies novel lncRNAs.
In: Genes, 14 (3)
doi: 10.3390/genes14030610
Artikel, Bibliographie

Göringer, H. Ulrich ; Knieß, Robert ; Leeder, Wolf-Matthias ; Reißig, Paul ; Geyer, Felix Klaus (2022)
Core-shell DNA-cholesterol nanoparticles exert lysosomolytic activity in African trypanosomes.
In: Chembiochem : a European journal of chemical biology, 23 (20)
doi: 10.1002/cbic.202200410
Artikel, Bibliographie

Leeder, Wolf-Matthias ; Geyer, Felix Klaus ; Göringer, H. Ulrich (2022)
Fuzzy RNA recognition by the Trypanosoma brucei editosome.
In: Nucleic acids research, 50 (10)
doi: 10.1093/nar/gkac357
Artikel, Bibliographie

Mueh, Mario ; Knieß, Robert ; Göringer, H. Ulrich ; Damm, Christian (2022)
Concepts for millimeter wave-based detection of African trypanosomes in field-compatible liquid systems.
In: Frequenz
doi: 10.1515/freq-2022-0113
Artikel, Bibliographie

Leeder, Wolf-Matthias ; Kruse, Elisabeth ; Göringer, H. Ulrich (2021)
Trypanosomatid, fluorescence-based U-insertion/U-deletion RNA-editing (FIDE).
In: Bio-protocol, 11 (5)
doi: 10.21769/BioProtoc.3935
Artikel, Bibliographie

Campo, Cristian del ; Leeder, Wolf-Matthias ; Reißig, Paul ; Göringer, H. Ulrich (2020)
Analyzing editosome function in high-throughput.
In: Nucleic acids research, 48 (17)
doi: 10.1093/nar/gkaa658
Artikel, Bibliographie

Aphasizheva, Inna ; Alfonzo, Juan ; Carnes, Jason ; Cestari, Igor ; Cruz-Reyes, Jorge ; Göringer, H. Ulrich ; Hajduk, Stephen ; Lukeš, Julius ; Madison-Antenucci, Susan ; Maslov, Dmitri A. ; McDermott, Suzanne M. ; Ochsenreiter, Torsten ; Read, Laurie K. ; Salavati, Reza ; Schnaufer, Achim ; Schneider, André ; Simpson, Larry ; Stuart, Kenneth ; Yurchenko, Vyacheslav ; Zhou, Z. Hong ; Zíková, Alena ; Zhang, Liye ; Zimmer, Sara ; Aphasizhev, Ruslan (2020)
Lexis and Grammar of Mitochondrial RNA Processing in Trypanosomes.
In: Trends in parasitology, 36 (4)
doi: 10.1016/j.pt.2020.01.006
Artikel, Bibliographie

Leeder, W.-Matthias ; Göringer, H. Ulrich (2020)
Mapping the RNA Chaperone Activity of the T. brucei Editosome Using SHAPE Chemical Probing.
In: Methods in molecular biology (Clifton, N.J.), 2106
doi: 10.1007/978-1-0716-0231-7_10
Artikel, Bibliographie

Lehr, François-Xavier ; Hanst, Maleen ; Vogel, Marc ; Kremer, Jennifer ; Göringer, H. Ulrich ; Suess, Beatrix ; Koeppl, Heinz (2019)
Cell-free prototyping of AND-logic gates based on heterogeneous RNA activators.
In: ACS Synthetic Biology, 8 (9)
doi: 10.1021/acssynbio.9b00238
Artikel, Bibliographie

Göringer, H. Ulrich ; Leeder, W.-Matthias ; Giehler, Fabian ; Joswig, Juliane (2019)
Bioinspired Design of Lysolytic Triterpenoid-Peptide Conjugates that Kill African Trypanosomes.
In: Chembiochem : a European journal of chemical biology, 20 (10)
doi: 10.1002/cbic.201800674
Artikel, Bibliographie

Shojaeian, Mostafa ; Lehr, François-Xavier ; Göringer, H. Ulrich ; Hardt, Steffen (2019)
On-Demand Production of Femtoliter Drops in Microchannels and Their Use as Biological Reaction Compartments.
In: Analytical Chemistry, 91 (5)
doi: 10.1021/acs.analchem.8b05063
Artikel, Bibliographie

Voigt, Christin ; Dobrychlop, Mateusz ; Kruse, Elisabeth ; Czerwoniec, Anna ; Kasprzak, Joanna M. ; Bytner, Patrycja ; Campo, Cristian del ; Leeder, W.-Matthias ; Bujnicki, Janusz M. ; Göringer, H. Ulrich (2018)
The OB-fold proteins of the Trypanosoma brucei editosome execute RNA-chaperone activity.
In: Nucleic acids research, 46 (19)
doi: 10.1093/nar/gky668
Artikel, Bibliographie

Kniess, Robert ; Wagner, Carolin B. ; Göringer, H. Ulrich ; Mueh, Mario ; Damm, Christian ; Sawallich, Simon ; Chmielak, Bartos ; Plachetka, Ulrich ; Lemme, Max (2018)
Towards the Development of THz-Sensors for the Detection of African Trypanosomes.
In: Frequenz, 72 (3-4)
Artikel, Bibliographie

Mueh, M. ; Maasch, M. ; Knieß, R. A. ; Göringer, H. Ulrich ; Damm, C. (2017)
Detection of African Trypanosomes Using Asymmetric Double-Split Ring Based THz Sensors.
In: IEEE Journal of Electromagnetics, RF and Microwaves in Medicine and Biology, 1 (2)
doi: 10.1109/JERM.2017.2771152
Artikel, Bibliographie

Leeder, Wolf-Matthias ; Voskuhl, Stephan ; Göringer, H. Ulrich (2017)
The 2D Structure of the T. brucei Preedited RPS12 mRNA Is Not Affected by Macromolecular Crowding.
In: Journal of nucleic acids
Artikel, Bibliographie

Leeder, W.-Matthias ; Hummel, Niklas F. C. ; Göringer, H. Ulrich (2016)
Multiple G-quartet structures in pre-edited mRNAs suggest evolutionary driving force for RNA editing in trypanosomes.
In: Scientific reports, 6
Artikel, Bibliographie

Leeder, W.-Matthias ; Voigt, Christin ; Brecht, Michael ; Göringer, H. Ulrich (2016)
The RNA chaperone activity of the Trypanosoma brucei editosome raises the dynamic of bound pre-mRNAs.
In: Scientific reports, 6
Artikel, Bibliographie

Leeder, W.-Matthias ; Reuss, Andreas J. ; Brecht, Michael ; Kratz, Katja ; Wachtveitl, Josef ; Göringer, H. Ulrich (2015)
Charge Reduction and Thermodynamic Stabilization of Substrate RNAs Inhibit RNA Editing.
In: PloS one, 10 (3)
Artikel, Bibliographie

Hofmeyer, Thomas ; Bulani, Siyavuya Ishmael ; Grzeschik, Julius ; Krah, Simon ; Glotzbach, Bernhard ; Uth, Christina ; Avrutina, Olga ; Brecht, Michael ; Göringer, H. Ulrich ; van Zyl, Petrus ; Kolmar, Harald (2014)
Protein Production in Yarrowia lipolytica Via Fusion to the Secreted Lipase Lip2p.
In: Molecular biotechnology, 56 (1)
Artikel, Bibliographie

Katari, Venkata Subbaraju ; Esdonk, Lea van ; Göringer, H. Ulrich (2013)
Molecular crowding inhibits u-insertion/deletion RNA editing in vitro: consequences for the in vivo reaction.
In: PloS one, 8 (12)
Artikel, Bibliographie

Kruse, Elisabeth ; Voigt, Christin ; Leeder, W.-Matthias ; Göringer, H. Ulrich (2013)
RNA helicases involved in U-insertion/deletion-type RNA editing.
In: Biochimica et biophysica acta - Gene regulation mechanisms, 1829 (8)
Artikel, Bibliographie

Zelada-Guillén, Gustavo A. ; Tweed-Kent, Ailis ; Niemann, Moritz ; Göringer, H. Ulrich ; Riu, Jordi ; Rius, F. Xavier (2013)
Ultrasensitive and real-time detection of proteins in blood using a potentiometric carbon-nanotube aptasensor.
In: Biosensors & bioelectronics, 41
Artikel, Bibliographie

Göringer, H. Ulrich (2012)
'Gestalt,' Composition and Function of the Trypanosoma brucei Editosome.
In: Annual review of microbiology, 66
Artikel, Bibliographie

Göringer, H. Ulrich (2012)
Parasite-specific aptamers as biosynthetic reagents and potential pharmaceuticals.
In: Trends in parasitology, 28 (3)
Artikel, Bibliographie

Böhm, Cordula ; Katari, Venkata Subbaraju ; Brecht, Michael ; Göringer, H. Ulrich (2012)
Trypanosoma brucei 20S editosomes have one RNA substrate-binding site and execute RNA unwinding activity.
In: The Journal of biological chemistry, 287 (31)
Artikel, Bibliographie

Prescott, C. D. ; Kleuvers, B. ; Göringer, H. Ulrich (2011)
A rRNA-mRNA base pairing model for UGA-dependent termination.
In: Biochimie, 73 (7-8)
Artikel, Bibliographie

Göringer, H. Ulrich ; Stark, Holger ; Böhm, Cordula ; Sander, Bjoern ; Golas, Monika M. (2011)
Three-dimensional reconstruction of Trypanosoma brucei editosomes using single-particle electron microscopy.
In: Methods in molecular biology (Clifton, N.J.), 718
Artikel, Bibliographie

Göringer, H. Ulrich ; Katari, Venkata Subbaraju ; Böhm, Cordula (2011)
The structural landscape of native editosomes in African trypanosomes.
In: Wiley interdisciplinary reviews. RNA, 2 (3)
Artikel, Bibliographie

Kölzer, Michael ; Weitzel, Kerstin ; Göringer, H. Ulrich ; Thines, Eckhard ; Opatz, Till (2010)
Synthesis of bioactive 2-aza-analogues of ipecac and alangium alkaloids.
In: ChemMedChem, 5 (9)
Artikel, Bibliographie

Niemann, Moritz ; Kaibel, Heike ; Schlüter, Elke ; Weitzel, Kerstin ; Brecht, Michael ; Göringer, H. Ulrich (2009)
Kinetoplastid RNA editing involves a 3' nucleotidyl phosphatase activity.
In: Nucleic acids research, 37 (6)
Artikel, Bibliographie

Golas, Monika M. ; Böhm, Cordula ; Sander, Bjoern ; Effenberger, Kerstin ; Brecht, Michael ; Stark, Holger ; Göringer, H. Ulrich (2009)
Snapshots of the RNA editing machine in trypanosomes captured at different assembly stages in vivo.
In: The EMBO journal, 28 (6)
Artikel, Bibliographie

Madej, Monika J. ; Niemann, Moritz ; Hüttenhofer, Alexander ; Göringer, H. Ulrich (2008)
Identification of novel guide RNAs from the mitochondria of Trypanosoma brucei.
In: RNA biology, 5 (2)
Artikel, Bibliographie

Adler, Annette ; Forster, Nicole ; Homann, Matthias ; Göringer, H. Ulrich (2008)
Post-SELEX chemical optimization of a trypanosome-specific RNA aptamer.
In: Combinatorial chemistry & high throughput screening, 11 (1)
Artikel, Bibliographie

Hrsg.: Göringer, H. Ulrich (2008)
RNA editing.
Buch, Bibliographie

Niemann, Moritz ; Brecht, Michael ; Schlüter, Elke ; Weitzel, Kerstin ; Zacharias, Martin ; Göringer, H. Ulrich (2008)
TbMP42 is a structure-sensitive ribonuclease that likely follows a metal ion catalysis mechanism.
In: Nucleic acids research, 36 (13)
Artikel, Bibliographie

König, Julian ; Julius, Christian ; Baumann, Sebastian ; Homann, Matthias ; Göringer, H. Ulrich ; Feldbrügge, Michael (2007)
Combining SELEX and the yeast three-hybrid system for in vivo selection and classification of RNA aptamers.
In: RNA (New York, N.Y.), 13 (4)
Artikel, Bibliographie

Göringer, H. Ulrich ; Homann, M. ; Zacharias, M. ; Adler, A. (2006)
RNA aptamers as potential pharmaceuticals against infections with African trypanosomes.
In: Handbook of experimental pharmacology, (173)
Artikel, Bibliographie

Homann, Matthias ; Lorger, Mihaela ; Engstler, Markus ; Zacharias, Martin ; Göringer, H. Ulrich (2006)
Serum-stable RNA aptamers to an invariant surface domain of live African trypanosomes.
In: Combinatorial chemistry & high throughput screening, 9 (7)
Artikel, Bibliographie

Best, Alexander ; Handoko, Lusy ; Schlüter, Elke ; Göringer, H. Ulrich (2005)
In vitro synthesized small interfering RNAs elicit RNA interference in african trypanosomes: an in vitro and in vivo analysis.
In: The Journal of biological chemistry, 280 (21)
Artikel, Bibliographie

Brecht, Michael ; Niemann, Moritz ; Schlüter, Elke ; Müller, Ulrich F. ; Stuart, Ken ; Göringer, H. Ulrich (2005)
TbMP42, a protein component of the RNA editing complex in African trypanosomes, has endo-exoribonuclease activity.
In: Molecular cell, 17 (5)
Artikel, Bibliographie

Göringer, H. Ulrich ; Homann, Matthias ; Lorger, Mihaela (2003)
In vitro selection of high-affinity nucleic acid ligands to parasite target molecules.
In: International journal for parasitology, 33 (12)
Artikel, Bibliographie

Lorger, Mihaela ; Engstler, Markus ; Homann, Matthias ; Göringer, H. Ulrich (2003)
Targeting the variable surface of African trypanosomes with variant surface glycoprotein-specific, serum-stable RNA aptamers.
In: Eukaryotic cell, 2 (1)
Artikel, Bibliographie

Müller, Ulrich F. ; Göringer, H. Ulrich (2002)
Mechanism of the gBP21-mediated RNA/RNA annealing reaction: matchmaking and charge reduction.
In: Nucleic acids research, 30 (2)
Artikel, Bibliographie

Müller, U. F. ; Lambert, L. ; Göringer, H. Ulrich (2001)
Annealing of RNA editing substrates facilitated by guide RNA-binding protein gBP21.
In: The EMBO journal, 20 (6)
Artikel, Bibliographie

Homann, M. ; Göringer, H. Ulrich (2001)
Uptake and intracellular transport of RNA aptamers in African trypanosomes suggest therapeutic "piggy-back" approach.
In: Bioorganic & medicinal chemistry, 9 (10)
Artikel, Bibliographie

Homann, M. ; Göringer, H. Ulrich (1999)
Combinatorial selection of high affinity RNA ligands to live African trypanosomes.
In: Nucleic acids research, 27 (9)
Artikel, Bibliographie

Missel, A. ; Lambert, L. ; Nörskau, G. ; Göringer, H. Ulrich (1999)
DEAD-box protein HEL64 from Trypanosoma brucei: subcellular localization and gene knockout analysis.
In: Parasitology research, 85 (4)
Artikel, Bibliographie

Hinz, S. ; Göringer, H. Ulrich (1999)
The guide RNA database (3.0).
In: Nucleic acids research, 27 (1)
Artikel, Bibliographie

Lambert, L. ; Müller, U. F. ; Souza, A. E. ; Göringer, H. Ulrich (1999)
The involvement of gRNA-binding protein gBP21 in RNA editing-an in vitro and in vivo analysis.
In: Nucleic acids research, 27 (6)
Artikel, Bibliographie

Allen, T. E. ; Heidmann, S. ; Reed, R. ; Myler, P. J. ; Göringer, H. Ulrich ; Stuart, K. D. (1998)
Association of guide RNA binding protein gBP21 with active RNA editing complexes in Trypanosoma brucei.
In: Molecular and cellular biology, 18 (10)
Artikel, Bibliographie

Shu, H. H. ; Göringer, H. Ulrich (1998)
Trypanosoma brucei mitochondrial ribonucleoprotein complexes which contain 12S and 9S ribosomal RNAs.
In: Parasitology, 116 (2)
Artikel, Bibliographie

Souza, A. E. ; Göringer, H. Ulrich (1998)
The guide RNA database.
In: Nucleic acids research, 26 (1)
Artikel, Bibliographie

Missel, A. ; Souza, A. E. ; Nörskau, G. ; Göringer, H. Ulrich (1997)
Disruption of a gene encoding a novel mitochondrial DEAD-box protein in Trypanosoma brucei affects edited mRNAs.
In: Molecular and cellular biology, 17 (9)
Artikel, Bibliographie

Köller, J. ; Müller, U. F. ; Schmid, B. ; Missel, A. ; Kruft, V. ; Stuart, K. ; Göringer, H. Ulrich (1997)
Trypanosoma brucei gBP21. An arginine-rich mitochondrial protein that binds to guide RNA with high affinity.
In: The Journal of biological chemistry, 272 (6)
Artikel, Bibliographie

Souza, A. E. ; Hermann, T. ; Göringer, H. Ulrich (1997)
The guide RNA database.
In: Nucleic acids research, 25 (1)
Artikel, Bibliographie

Hermann, T. ; Schmid, B. ; Heumann, H. ; Göringer, H. Ulrich (1997)
A three-dimensional working model for a guide RNA from Trypanosoma brucei.
In: Nucleic acids research, 25 (12)
Artikel, Bibliographie

Schmid, B. ; Read, L. K. ; Stuart, K. ; Göringer, H. Ulrich (1996)
Experimental verification of the secondary structures of guide RNA-pre-mRNA chimaeric molecules in Trypanosoma brucei.
In: European journal of biochemistry / FEBS, 240 (3)
Artikel, Bibliographie

Shu, H. H. ; Stuart, K. ; Göringer, H. Ulrich (1995)
Guide RNA molecules not engaged in RNA editing form ribonucleoprotein complexes free of mRNA.
In: Biochimica et biophysica acta, 1261 (3)
Artikel, Bibliographie

Missel, A. ; Nörskau, G. ; Shu, H. H. ; Göringer, H. Ulrich (1995)
A putative RNA helicase of the DEAD box family from Trypanosoma brucei.
In: Molecular and biochemical parasitology, 75 (1)
Artikel, Bibliographie

Schmid, B. ; Riley, G. R. ; Stuart, K. ; Göringer, H. Ulrich (1995)
The secondary structure of guide RNA molecules from Trypanosoma brucei.
In: Nucleic acids research, 23 (16)
Artikel, Bibliographie

Read, L. K. ; Göringer, H. Ulrich ; Stuart, K. (1994)
Assembly of mitochondrial ribonucleoprotein complexes involves specific guide RNA (gRNA)-binding proteins and gRNA domains but does not require preedited mRNA.
In: Molecular and cellular biology, 14 (4)
Artikel, Bibliographie

Köller, J. ; Nörskau, G. ; Paul, A. S. ; Stuart, K. ; Göringer, H. Ulrich (1994)
Different Trypanosoma brucei guide RNA molecules associate with an identical complement of mitochondrial proteins in vitro.
In: Nucleic acids research, 22 (11)
Artikel, Bibliographie

Missel, A. ; Göringer, H. Ulrich (1994)
Trypanosoma brucei mitochondria contain RNA helicase activity.
In: Nucleic acids research, 22 (20)
Artikel, Bibliographie

Göringer, H. Ulrich ; Koslowsky, D. J. ; Morales, T. H. ; Stuart, K. (1994)
The formation of mitochondrial ribonucleoprotein complexes involving guide RNA molecules in Trypanosoma brucei.
In: Proceedings of the National Academy of Sciences of the United States of America, 91 (5)
Artikel, Bibliographie

Zacharias, M. ; Göringer, H. Ulrich ; Wagner, R. (1992)
Analysis of the Fis-dependent and Fis-independent transcription activation mechanisms of the Escherichia coli ribosomal RNA P1 promoter.
In: Biochemistry, 31 (9)
Artikel, Bibliographie

Koslowsky, D. J. ; Göringer, H. Ulrich ; Morales, T. H. ; Stuart, K. (1992)
In vitro guide RNA/mRNA chimaera formation in Trypanosoma brucei RNA editing.
In: Nature, 356 (6372)
Artikel, Bibliographie

O'Connor, M. ; Göringer, H. Ulrich ; Dahlberg, A. E. (1992)
A ribosomal ambiguity mutation in the 530 loop of E. coli 16S rRNA.
In: Nucleic acids research, 20 (16)
Artikel, Bibliographie

Göringer, H. Ulrich ; Hijazi, K. A. ; Murgola, E. J. ; Dahlberg, A. E. (1991)
Mutations in 16S rRNA that affect UGA (stop codon)-directed translation termination.
In: Proceedings of the National Academy of Sciences of the United States of America, 88 (15)
Artikel, Bibliographie

Zacharias, M. ; Wagner, R. ; Göringer, H. Ulrich (1990)
Polyacrylamide gradient gel electrophoresis for the detection of bended DNA fragments.
In: Nucleic acids research, 18 (9)
Artikel, Bibliographie

Hänfler, A. ; Kleuvers, B. ; Göringer, H. Ulrich (1990)
The involvement of base 1054 in 16S rRNA for UGA stop codon dependent translational termination.
In: Nucleic acids research, 18 (19)
Artikel, Bibliographie

Zacharias, M. ; Göringer, H. Ulrich ; Wagner, R. (1990)
The signal for growth rate control and stringent sensitivity in E. coli is not restricted to a particular sequence motif within the promoter region.
In: Nucleic acids research, 18 (21)
Artikel, Bibliographie

Prescott, C. D. ; Göringer, H. Ulrich (1990)
A single mutation in 16S rRNA that affects mRNA binding and translation-termination.
In: Nucleic acids research, 18 (18)
Artikel, Bibliographie

Zacharias, M. ; Göringer, H. Ulrich ; Wagner, R. (1989)
Influence of the GCGC discriminator motif introduced into the ribosomal RNA P2- and tac promoter on growth-rate control and stringent sensitivity.
In: The EMBO journal, 8 (11)
Artikel, Bibliographie

Göringer, H. Ulrich ; Wagner, R. (1988)
5S RNA structure and function.
In: Methods in enzymology, 164
Artikel, Bibliographie

Murgola, E. J. ; Hijazi, K. A. ; Göringer, H. Ulrich ; Dahlberg, A. E. (1988)
Mutant 16S ribosomal RNA: a codon-specific translational suppressor.
In: Proceedings of the National Academy of Sciences of the United States of America, 85 (12)
Artikel, Bibliographie

Göringer, H. Ulrich ; Wagner, R. (1986)
Construction and functional analysis of ribosomal 5S RNA from Escherichia coli with single base changes in the ribosomal protein binding sites.
In: Biological chemistry Hoppe-Seyler, 367 (8)
Artikel, Bibliographie

Göringer, H. Ulrich ; Wagner, R. (1986)
Does 5S RNA from E. coli have a pseudoknotted structure?
In: Nucleic acids research, 14 (18)
Artikel, Bibliographie

Meier, N. ; Göringer, H. Ulrich ; Kleuvers, B. ; Scheibe, U. ; Eberle, J. ; Szymkowiak, C. ; Zacharias, M. ; Wagner, R. (1986)
The importance of individual nucleotides for the structure and function of rRNA molecules in E. coli. A mutagenesis study.
In: FEBS letters, 204 (1)
Artikel, Bibliographie

Göringer, H. Ulrich ; Szymkowiak, C. ; Wagner, R. (1984)
Escherichia coli 5S RNA A and B conformers. Characterisation by enzymatic and chemical methods.
In: European journal of biochemistry / FEBS, 144 (1)
Artikel, Bibliographie

Göringer, H. Ulrich ; Wagner, R. ; Jacob, W. F. ; Dahlberg, A. E. ; Zwieb, C. (1984)
Oligonucleotide directed mutagenesis of Escherichia coli 5S ribosomal RNA: construction of mutant and structural analysis.
In: Nucleic acids research, 12 (18)
Artikel, Bibliographie

Göringer, H. Ulrich ; Bertram, S. ; Wagner, R. (1984)
The effect of tRNA binding on the structure of 5 S RNA in Escherichia coli. A chemical modification study.
In: The Journal of biological chemistry, 259 (1)
Artikel, Bibliographie

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