Arras, Paul ; Zimmermann, Jasmin ; Lipinski, Britta ; Valldorf, Bernhard ; Evers, Andreas ; Elter, Desislava ; Krah, Simon ; Doerner, Achim ; Guarnera, Enrico ; Siegmund, Vanessa ; Kolmar, Harald ; Pekar, Lukas ; Zielonka, Stefan (2024)
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features.
In: Biological Chemistry
doi: 10.1515/hsz-2023-0370
Artikel, Bibliographie

Lipinski, Britta ; Arras, Paul ; Pekar, Lukas ; Klewinghaus, Daniel ; Boje, Ammelie Svea ; Krah, Simon ; Zimmermann, Jasmin ; Klausz, Katja ; Peipp, Matthias ; Siegmund, Vanessa ; Evers, Andreas ; Zielonka, Stefan (2023)
NKp46‐specific single domain antibodies enable facile engineering of various potent NK cell engager formats.
In: Protein Science, 32 (3)
doi: 10.1002/pro.4593
Artikel, Bibliographie

Klewinghaus, Daniel ; Pekar, Lukas ; Arras, Paul ; Krah, Simon ; Valldorf, Bernhard ; Kolmar, Harald ; Zielonka, Stefan (2022)
Grabbing the Bull by Both Horns: Bovine Ultralong CDR-H3 Paratopes Enable Engineering of ‘Almost Natural’ Common Light Chain Bispecific Antibodies Suitable For Effector Cell Redirection.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.801368
Artikel, Bibliographie

Pekar, Lukas ; Klewinghaus, Daniel ; Arras, Paul ; Carrara, Stefania C. ; Harwardt, Julia ; Krah, Simon ; Yanakieva, Desislava ; Toleikis, Lars ; Smider, Vaughn V. ; Kolmar, Harald ; Zielonka, Stefan (2021)
Milking the cow: cattle-derived chimeric ultralong CDR-H3 antibodies and their engineered CDR-H3-only knobbody counterparts targeting epidermal growth factor receptor elicit potent NK cell-mediated cytotoxicity.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.742418
Artikel, Bibliographie

Macarrón Palacios, Arturo ; Grzeschik, Julius ; Deweid, Lukas ; Krah, Simon ; Zielonka, Stefan ; Rösner, Thies ; Peipp, Matthias ; Valerius, Thomas ; Kolmar, Harald (2020)
Specific targeting of lymphoma cells using semisynthetic anti-idiotype shark antibodies.
In: Frontiers in Immunology, 11
doi: 10.3389/fimmu.2020.560244
Artikel, Bibliographie

Bogen, Jan P. ; Hinz, Steffen C. ; Grzeschik, Julius ; Ebenig, Aileen ; Krah, Simon ; Zielonka, Stefan ; Kolmar, Harald (2019)
Dual function pH responsive bispecific antibodies for tumor targeting and antigen depletion in plasma.
In: Frontiers in Immunology, 10
doi: 10.3389/fimmu.2019.01892
Artikel, Bibliographie

Krah, Simon ; Kolmar, Harald ; Becker, Stefan ; Zielonka, Stefan (2018)
Engineering IgG-like bispecific antibodies — an overview.
In: Antibodies, 7 (3)
doi: 10.3390/antib7030028
Artikel, Bibliographie

Schröter, Christian ; Becker, Jan ; Krah, Simon ; Zielonka, Stefan ; Doerner, Achim ; Rhiel, Laura ; Günther, Ralf ; Toleikis, Lars ; Kolmar, Harald ; Hock, Björn ; Becker, Stefan (2018)
Selection of antibodies with tailored properties by application of high-throughput multiparameter fluorescence-activated cell sorting of yeast-displayed immune libraries.
In: Molecular Biotechnology, 60
doi: 10.1007/s12033-018-0109-0
Artikel, Bibliographie

Krah, Simon (2017)
Novel yeast display based screening technologies for the generation of tailor-made human antibodies.
Technische Universität Darmstadt
Dissertation, Bibliographie

Hofmeyer, Thomas ; Bulani, Siyavuya Ishmael ; Grzeschik, Julius ; Krah, Simon ; Glotzbach, Bernhard ; Uth, Christina ; Avrutina, Olga ; Brecht, Michael ; Göringer, H. Ulrich ; van Zyl, Petrus ; Kolmar, Harald (2014)
Protein Production in Yarrowia lipolytica Via Fusion to the Secreted Lipase Lip2p.
In: Molecular biotechnology, 56 (1)
Artikel, Bibliographie

Rhiel, Laura ; Krah, Simon ; Günther, Ralf ; Becker, Stefan ; Kolmar, Harald ; Hock, Björn (2014)
REAL-select: full-length antibody display and library screening by surface capture on yeast cells.
In: PLOS ONE, 9 (12)
doi: 10.1371/journal.pone.0114887
Artikel, Bibliographie