Englisch

Brackmann, Lara Kim ; Foraita, Ronja ; Schwarz, Heike ; Galetzka, Danuta ; Zahnreich, Sebastian ; Hankeln, Thomas ; Löbrich, Markus ; Poplawski, Alicia ; Grabow, Desiree ; Blettner, Maria ; Schmidberger, Heinz ; Marron, Manuela (2022)
Late health effects and changes in lifestyle factors after cancer in childhood with and without subsequent second primary cancers - the KiKme case-control study.
In: Frontiers in oncology, 12
doi: 10.3389/fonc.2022.1037276
Artikel, Bibliographie

Llorens-Agost, Marta ; Ensminger, Michael ; Le, Hang Phuong ; Gawai, Anugrah ; Liu, Jie ; Cruz-García, Andrés ; Bhetawal, Sarita ; Wood, Richard D. ; Heyer, Wolf-Dietrich ; Löbrich, Markus (2021)
Publisher Correction: POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.
In: Nature cell biology
doi: 10.1038/s41556-021-00797-5
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Llorens-Agost, Marta ; Ensminger, Michael ; Le, Hang Phuong ; Gawai, Anugrah ; Liu, Jie ; Cruz-García, Andrés ; Bhetawal, Sarita ; Wood, Richard D. ; Heyer, Wolf-Dietrich ; Löbrich, Markus (2021)
POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.
In: Nature cell biology, 23 (10)
doi: 10.1038/s41556-021-00764-0
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Elbakry, Amira ; Löbrich, Markus (2021)
Homologous Recombination Subpathways : a Tangle to Resolve.
In: Frontiers in genetics, 12
doi: 10.3389/fgene.2021.723847
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Elbakry, Amira ; Juhász, Szilvia ; Chan, Ki Choi ; Löbrich, Markus (2021)
ATRX and RECQ5 define distinct homologous recombination subpathways.
In: Proceedings of the National Academy of Sciences of the United States of America, 118 (3)
doi: 10.1073/pnas.2010370118
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Llorens-Agost, Marta ; Ensminger, Michael ; Le, Hang Phuong ; Heyer, Wolf-Dietrich ; Löbrich, Markus (2021)
Turning end-joining upside down in mitosis.
In: Molecular & cellular oncology, 8 (6)
doi: 10.1080/23723556.2021.2007029
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Mirsch, Johanna ; Hintz, Lisa ; Maier, Andreas ; Fournier, Claudia ; Löbrich, Markus (2020)
An assessment of radiation doses from radon exposures using a mouse model system.
In: International journal of radiation oncology, biology, physics, 108 (3)
doi: 10.1016/j.ijrobp.2020.05.031
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Zahnreich, Sebastian ; Poplawski, Alicia ; Hartel, Carola ; Eckhard, Lukas Stefan ; Galetzka, Danuta ; Hankeln, Thomas ; Löbrich, Markus ; Marron, Manuela ; Mirsch, Johanna ; Ritter, Sylvia ; Scholz-Kreisel, Peter ; Spix, Claudia ; Schmidberger, Heinz (2020)
Spontaneous and Radiation-Induced Chromosome Aberrations in Primary Fibroblasts of Patients With Pediatric First and Second Neoplasms.
In: Frontiers in oncology, 10
doi: 10.3389/fonc.2020.01338
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Freund, Isabel ; Hehlgans, Stephanie ; Martin, Daniel ; Ensminger, Michael ; Fokas, Emmanouil ; Rödel, Claus ; Löbrich, Markus ; Rödel, Franz (2020)
Fractionation-Dependent Radiosensitization by Molecular Targeting of Nek1.
In: Cells, 9 (5)
doi: 10.3390/cells9051235
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Frohns, Florian ; Frohns, Antonia ; Kramer, Johanna ; Meurer, Katharina ; Rohrer-Bley, Carla ; Solovei, Irina ; Hicks, David ; Layer, Paul G. ; Löbrich, Markus (2020)
Differences in the Response to DNA Double-Strand Breaks between Rod Photoreceptors of Rodents, Pigs, and Humans.
In: Cells, 9 (4)
doi: 10.3390/cells9040947
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Ensminger, Michael ; Löbrich, Markus (2020)
One end to rule them all: Non-homologous end-joining and homologous recombination at DNA double-strand breaks.
In: The British journal of radiology, 93 (1115)
doi: 10.1259/bjr.20191054
Artikel, Bibliographie

Löbrich, Markus ; Jeggo, Penny A. (2019)
Hazards of human spaceflight.
In: Science (New York, N.Y.), 364 (6436)
doi: 10.1126/science.aaw7086
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Lengert, Nicor ; Mirsch, Johanna ; Weimer, Ratna N. ; Schumann, Eik ; Haub, Peter ; Drossel, Barbara ; Löbrich, Markus (2018)
AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair.
In: Scientific reports, 8 (1)
Artikel, Bibliographie

Shibata, Atsushi ; Jeggo, Penny ; Löbrich, Markus (2018)
The pendulum of the Ku-Ku clock.
In: DNA repair, 71
Artikel, Bibliographie

Elbakry, Amira ; Juhász, Szilvia ; Mathes, Arthur ; Löbrich, Markus (2018)
DNA repair synthesis and histone deposition partner during homologous recombination.
In: Molecular & cellular oncology, 5 (5)
Artikel, Bibliographie

Juhász, Szilvia ; Elbakry, Amira ; Mathes, Arthur ; Löbrich, Markus (2018)
ATRX Promotes DNA Repair Synthesis and Sister Chromatid Exchange during Homologous Recombination.
In: Molecular cell, 71 (1)
Artikel, Bibliographie

Jeggo, Penny A. ; Löbrich, Markus (2017)
DNA non-homologous end-joining enters the resection arena.
In: Oncotarget, 8 (55)
Artikel, Bibliographie

Löbrich, Markus ; Jeggo, Penny (2017)
A Process of Resection-Dependent Nonhomologous End Joining Involving the Goddess Artemis.
In: Trends in biochemical sciences, 42 (9)
Artikel, Bibliographie

Essary, T. ; Oppermann, J. ; Weipert, F. ; Löbrich, Markus ; Roedel, C. ; Roedel, F. ; Hehlgans, S. (2017)
Modulation of the cellular Radiation Response in colorectal Cells after Inhibition of the DNA-Repair Factor Nek1.
In: Strahlentherapie und Onkologie, 193
Artikel, Bibliographie

Biehs, Ronja ; Steinlage, Monika ; Barton, Olivia ; Juhász, Szilvia ; Künzel, Julia ; Spies, Julian ; Shibata, Atsushi ; Jeggo, Penny A. ; Löbrich, Markus (2017)
DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination.
In: Molecular cell, 65 (4)
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Spies, Julian ; Waizenegger, Anja ; Barton, Olivia ; Sürder, Michael ; Wright, William D. ; Heyer, Wolf-Dietrich ; Löbrich, Markus (2016)
Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.
In: Molecular cell, 62 (6)
Artikel, Bibliographie

Mirsch, Johanna ; Tommasino, Francesco ; Frohns, Antonia ; Conrad, Sandro ; Durante, Marco ; Scholz, Michael ; Friedrich, Thomas ; Löbrich, Markus (2015)
Direct measurement of the 3-dimensional DNA lesion distribution induced by energetic charged particles in a mouse model tissue.
In: Proceedings of the National Academy of Sciences of the United States of America, 112 (40)
Artikel, Bibliographie

Jeggo, Penny A. ; Löbrich, Markus (2015)
How cancer cells hijack DNA double-strand break repair pathways to gain genomic instability.
In: The Biochemical journal, 471 (1)
Artikel, Bibliographie

Makharashvili, Nodar ; Tubbs, Anthony T. ; Yang, Soo-Hyun ; Wang, Hailong ; Barton, Olivia ; Zhou, Yi ; Deshpande, Rajashree A. ; Lee, Ji-Hoon ; Löbrich, Markus ; Sleckman, Barry P. ; Wu, Xiaohua ; Paull, Tanya T. (2014)
Catalytic and Noncatalytic Roles of the CtIP Endonuclease in Double-Strand Break End Resection.
In: Molecular cell, 54 (6)
Artikel, Bibliographie

Ensminger, Michael ; Iloff, Lucie ; Ebel, Christian ; Nikolova, Teodora ; Kaina, Bernd ; Löbrich, Markus (2014)
DNA breaks and chromosomal aberrations arise when replication meets base excision repair.
In: The Journal of cell biology, 206 (1)
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Frohns, Antonia ; Frohns, Florian ; Naumann, Steffen C. ; Layer, Paul G. ; Löbrich, Markus (2014)
Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin Organization.
In: Current biology : CB, 24 (10)
Artikel, Bibliographie

Wang, Jiadong ; Aroumougame, Asaithamby ; Löbrich, Markus ; Li, Yujing ; Chen, David ; Chen, Junjie ; Gong, Zihua (2014)
PTIP associates with Artemis to dictate DNA repair pathway choice.
In: Genes & development, 28 (24)
Artikel, Bibliographie

Barton, Olivia ; Naumann, Steffen C. ; Diemer-Biehs, Ronja ; Künzel, Julia ; Steinlage, Monika ; Conrad, Sandro ; Makharashvili, Nodar ; Wang, Jiadong ; Feng, Lin ; Lopez, Bernard S. ; Paull, Tanya T. ; Chen, Junjie ; Jeggo, Penny A. ; Löbrich, Markus (2014)
Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.
In: The Journal of cell biology, 206 (7)
Artikel, Bibliographie

Kakarougkas, Andreas ; Ismail, Amani ; Chambers, Anna L. ; Riballo, Enriqueta ; Herbert, Alex D. ; Künzel, Julia ; Löbrich, Markus ; Jeggo, Penny A. ; Downs, Jessica A. (2014)
Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin.
In: Molecular cell, 55 (5)
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Singh, Mayank ; Hunt, Clayton R. ; Pandita, Raj K. ; Kumar, Rakesh ; Yang, Chin-Rang ; Horikoshi, Nobuo ; Bachoo, Robert ; Serag, Sara ; Story, Michael D. ; Shay, Jerry W. ; Powell, Simon N. ; Gupta, Arun ; Jeffery, Jessie ; Pandita, Shruti ; Chen, Benjamin P. C. ; Deckbar, Dorothee ; Löbrich, Markus ; Yang, Qin ; Khanna, Kum Kum ; Worman, Howard J. ; Pandita, Tej K. (2013)
Lamin A/C depletion enhances DNA damage-induced stalled replication fork arrest.
In: Molecular and cellular biology, 33 (6)
Artikel, Bibliographie

Geuting, Verena ; Reul, Christian ; Löbrich, Markus (2013)
ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination.
In: PLoS genetics, 9 (8)
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Fischer, Ulrike ; Rheinheimer, Stefanie ; Krempler, Andrea ; Löbrich, Markus ; Meese, Eckart (2013)
Glioma-amplified sequence KUB3 influences double-strand break repair after ionizing radiation.
In: International journal of oncology, 43 (1)
Artikel, Bibliographie

Kakarougkas, Andreas ; Ismail, Amani ; Klement, Karolin ; Goodarzi, Aaron A. ; Conrad, Sandro ; Freire, Raimundo ; Shibata, Atsushi ; Löbrich, Markus ; Jeggo, Penny A. (2013)
Opposing roles for 53BP1 during homologous recombination.
In: Nucleic acids research, 41 (21)
Artikel, Bibliographie

Löbrich, Markus (2012)
Double strand break repair and checkpoint control after low radiation doses [Abstracts of the 34th Annual Meeting of the United Kingdom Environmental Mutagen Society, 29th June – 1st July 2011].
In: Mutagenesis, 27 (1)
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Brand, Michael ; Sommer, Matthias ; Achenbach, Stephan ; Anders, Katharina ; Lell, Michael ; Löbrich, Markus ; Uder, Michael ; Kuefner, Michael A. (2012)
X-ray induced DNA double-strand breaks in coronary CT angiography: Comparison of sequential, low-pitch helical and high-pitch helical data acquisition.
In: European journal of radiology, 81 (3)
Artikel, Bibliographie

Quennet, Verena ; Beucher, Andrea ; Barton, Olivia ; Takeda, Shunichi ; Löbrich, Markus (2011)
CtIP and MRN promote non-homologous end-joining of etoposide-induced DNA double-strand breaks in G1.
In: Nucleic acids research, 39 (6)
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Jakob, Burkhard ; Splinter, Jörn ; Conrad, Sandro ; Voss, Kay-Obbe ; Zink, Daniele ; Durante, Marco ; Löbrich, Markus ; Taucher-Scholz, Gisela (2011)
DNA double-strand breaks in heterochromatin elicit fast repair protein recruitment, histone H2AX phosphorylation and relocation to euchromatin.
In: Nucleic acids research, 39 (15)
Artikel, Bibliographie

Beucher, Andrea ; Deckbar, Dorothee ; Schumann, Eik ; Krempler, Andrea ; Frankenberg-Schwager, Marlis ; Löbrich, Markus (2011)
Elevated radiation-induced γH2AX foci in G2 phase heterozygous BRCA2 fibroblasts.
In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 101 (1)
Artikel, Bibliographie

Shibata, Atsushi ; Conrad, Sandro ; Birraux, Julie ; Geuting, Verena ; Barton, Olivia ; Ismail, Amani ; Kakarougkas, Andreas ; Meek, Katheryn ; Taucher-Scholz, Gisela ; Löbrich, Markus ; Jeggo, Penny A. (2011)
Factors determining DNA double-strand break repair pathway choice in G2 phase.
In: The EMBO journal
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Conrad, Sandro ; Künzel, Julia ; Löbrich, Markus (2011)
Sister chromatid exchanges occur in G2-irradiated cells.
In: Cell cycle (Georgetown, Tex.), 10 (2)
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Deckbar, Dorothee ; Jeggo, Penny A. ; Löbrich, Markus (2011)
Understanding the limitations of radiation-induced cell cycle checkpoints.
In: Critical reviews in biochemistry and molecular biology, 46 (4)
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Jeggo, Penny A. ; Geuting, Verena ; Löbrich, Markus (2011)
The role of homologous recombination in radiation-induced double-strand break repair.
In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 101 (1)
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Nikolova, Teodora ; Ensminger, Michael ; Löbrich, Markus ; Kaina, Bernd (2010)
Homologous recombination protects mammalian cells from replication-associated DNA double-strand breaks arising in response to methyl methanesulfonate.
In: DNA repair, 9 (10)
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Grudzenski, Saskia ; Raths, Antonia ; Conrad, Sandro ; Rübe, Claudia E. ; Löbrich, Markus (2010)
Inducible response required for repair of low-dose radiation damage in human fibroblasts.
In: Proceedings of the National Academy of Sciences of the United States of America, 107 (32)
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Kuefner, Michael A. ; Hinkmann, Fabian M. ; Alibek, Sedat ; Azoulay, Sascha ; Anders, Katharina ; Kalender, Willi A. ; Achenbach, Stephan ; Grudzenski, Saskia ; Löbrich, Markus ; Uder, Michael (2010)
Reduction of X-ray induced DNA double-strand breaks in blood lymphocytes during coronary CT angiography using high-pitch spiral data acquisition with prospective ECG-triggering.
In: Investigative radiology, 45 (4)
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Shibata, Atsushi ; Barton, Olivia ; Noon, Angela T. ; Dahm, Kirsten ; Deckbar, Dorothee ; Goodarzi, Aaron A. ; Löbrich, Markus ; Jeggo, Penny A. (2010)
Role of ATM and the damage response mediator proteins 53BP1 and MDC1 in the maintenance of G(2)/M checkpoint arrest.
In: Molecular and cellular biology, 30 (13)
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Löbrich, Markus ; Shibata, Atsushi ; Beucher, Andrea ; Fisher, Anna ; Ensminger, Michael ; Goodarzi, Aaron A. ; Barton, Olivia ; Jeggo, Penny A. (2010)
gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization.
In: Cell cycle (Georgetown, Tex.), 9 (4)
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Goodarzi, Aaron A. ; Jeggo, Penny ; Löbrich, Markus (2010)
The influence of heterochromatin on DNA double strand break repair: Getting the strong, silent type to relax.
In: DNA repair, 9 (12)
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Deckbar, Dorothee ; Stiff, Thomas ; Koch, Barbara ; Reis, Caroline ; Löbrich, Markus ; Jeggo, Penny A. (2010)
The limitations of the G1-S checkpoint.
In: Cancer research, 70 (11)
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