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DNA repair synthesis and histone deposition partner during homologous recombination.

Elbakry, Amira and Juhász, Szilvia and Mathes, Arthur and Löbrich, Markus :
DNA repair synthesis and histone deposition partner during homologous recombination.
In: Molecular & cellular oncology, 5 (5) e1511210. ISSN 2372-3556
[Article] , (2018)

Abstract

Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chromatin remodeling complex regulates DNA repair synthesis during homologous recombination.

Item Type: Article
Erschienen: 2018
Creators: Elbakry, Amira and Juhász, Szilvia and Mathes, Arthur and Löbrich, Markus
Title: DNA repair synthesis and histone deposition partner during homologous recombination.
Language: English
Abstract:

Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and the death domain associated protein (DAXX) chromatin remodeling complex regulates DNA repair synthesis during homologous recombination.

Journal or Publication Title: Molecular & cellular oncology
Volume: 5
Number: 5
Divisions: 10 Department of Biology
10 Department of Biology > Radiation Biology and DNA Repair
Date Deposited: 09 Oct 2018 08:03
Identification Number: pmid:30263950
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