Artikel

Tewes, Noel ; Kubitzki, Beatrice ; Bytyqi, Flandrit ; Metko, Nikola ; Mach, Sebastian ; Thiel, Gerhard ; Rauh, Oliver (2024)
Mutation in pore-helix modulates interplay between filter gate and Ba2+ block in a Kcv channel pore.
In: The Journal of general physiology, 156 (5)
doi: 10.1085/jgp.202313514
Artikel, Bibliographie

Eisenhauer, Klara ; Weber, Wadim ; Kemp, Philipp ; Gebhardt, Carolin ; Kaufmann, Marwan ; Tewes, Noel ; Zhdanova, Hanna ; Tietze, Alesia ; Rauh, Oliver ; Stein, Viktor (2024)
Scaling the Functional Nanopore (FuN) Screen: systematic evaluation of self-assembling membrane peptides and extension with a K+-responsive fluorescent protein sensor.
In: ACS synthetic biology, 13 (4)
doi: 10.1021/acssynbio.3c00671
Artikel, Bibliographie

Krumbach, Jan H. ; Bauer, Daniel ; Sharifzadeh, Atiyeh Sadat ; Saponaro, Andrea ; Lautenschläger, Rene ; Lange, Kristina ; Rauh, Oliver ; DiFrancesco, Dario ; Moroni, Anna ; Thiel, Gerhard ; Hamacher, Kay (2023)
Alkali metal cations modulate the geometry of different binding sites in HCN4 selectivity filter for permeation or block.
In: The Journal of general physiology, 155 (10)
doi: 10.1085/jgp.202313364
Artikel, Bibliographie

Engel, Anja J. ; Paech, Steffen ; Langhans, Markus ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2023)
Combination of hydrophobicity and codon usage bias determines sorting of model K+ channel protein to either mitochondria or endoplasmic reticulum.
In: Traffic, 24 (11)
doi: 10.1111/tra.12915
Artikel, Bibliographie

Höler, Sebastian ; Degreif, Daniel ; Stix, Florentine ; Yang, Shang ; Gao, Shiqiang ; Nagel, Georg ; Moroni, Anna ; Thiel, Gerhard ; Bertl, Adam ; Rauh, Oliver (2023)
Tailoring baker's yeast Saccharomyces cerevisiae for functional testing of channelrhodopsin.
In: PloS one, 18 (4)
doi: 10.1371/journal.pone.0280711
Artikel, Bibliographie

Rauh, Oliver ; Opper, Jennifer ; Sturm, Maximilian ; Drexler, Nils ; Scheub, Deborah D. ; Hansen, Ulf-Peter ; Thiel, Gerhard ; Schroeder, Indra (2022)
Role of ion distribution and energy barriers for concerted motion of subunits in selectivity filter gating of a K+ channel.
In: Journal of molecular biology, 434 (9)
doi: 10.1016/j.jmb.2022.167522
Artikel, Bibliographie

Carvalho-de-Souza, Joao Luis ; Saponaro, Andrea ; Bassetto, C. A. Z. ; Rauh, Oliver ; Schroeder, Indra ; Franciolini, Fabio ; Catacuzzeno, Luigi ; Bezanilla, Francisco ; Thiel, Gerhard ; Moroni, Anna (2022)
Experimental challenges in ion channel research : uncovering basic principles of permeation and gating in potassium channels.
In: Advances in Physics: X, 7 (1)
doi: 10.1080/23746149.2021.1978317
Artikel, Bibliographie

Köhs, Lukas ; Kukovetz, Kerri ; Rauh, Oliver ; Koeppl, Heinz (2022)
Nonparametric Bayesian inference for meta-stable conformational dynamics.
In: Physical Biology, 19 (5)
doi: 10.1088/1478-3975/ac885e
Artikel, Bibliographie

Gabriel, Tobias S. ; Hansen, Ulf-Peter ; Urban, Martin ; Drexler, Nils ; Winterstein, Tobias ; Rauh, Oliver ; Thiel, Gerhard ; Kast, Stefan M. ; Schroeder, Indra (2021)
Asymmetric Interplay Between K+ and Blocker and Atomistic Parameters From Physiological Experiments Quantify K+ Channel Blocker Release.
In: Frontiers in physiology, 12
doi: 10.3389/fphys.2021.737834
Artikel, Bibliographie

Conti Nibali, Stefano ; Di Rosa, Maria Carmela ; Rauh, Oliver ; Thiel, Gerhard ; Reina, Simona ; De Pinto, Vito (2021)
Cell-free electrophysiology of human VDACs incorporated into nanodiscs : an improved method.
In: Biophysical reports, 1 (1)
doi: 10.1016/j.bpr.2021.100002
Artikel, Bibliographie

Engel, Anja J. ; Kithil, Marina ; Langhans, Markus ; Rauh, Oliver ; Cartolano, Matea ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard (2021)
Codon Bias Can Determine Sorting of a Potassium Channel Protein.
In: Cells, 10 (5)
doi: 10.3390/cells10051128
Artikel, Bibliographie

Rauh, Oliver ; Kukovetz, Kerri ; Winterstein, Laura ; Introini, Bianca ; Thiel, Gerhard (2021)
Combining in vitro translation with nanodisc technology and functional reconstitution of channels in planar lipid bilayers.
In: Methods in enzymology, 652
doi: 10.1016/bs.mie.2021.02.003
Artikel, Bibliographie

Winterstein, Laura-Marie ; Kukovetz, Kerri ; Hansen, Ulf-Peter ; Schroeder, Indra ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2021)
Distinct lipid bilayer compositions have general and protein-specific effects on K+ channel function.
In: The Journal of general physiology, 153 (2)
doi: 10.1085/jgp.202012731
Artikel, Bibliographie

Scheiper-Welling, Stefanie ; Zuccolini, Paolo ; Rauh, Oliver ; Beckmann, Britt-Maria ; Geisen, Christof ; Moroni, Anna ; Thiel, Gerhard ; Kauferstein, Silke (2020)
Characterization of an N-terminal Na v 1.5 channel variant - a potential risk factor for arrhythmias and sudden death?
In: BMC medical genetics, 21 (1)
doi: 10.1186/s12881-020-01170-3
Artikel, Bibliographie

Kukovetz, Kerri ; Hertel, Brigitte ; Schvarcz, Christopher R. ; Saponaro, Andrea ; Manthey, Mirja ; Burk, Ulrike ; Greiner, Timo ; Steward, Grieg F. ; Etten, James L. van ; Moroni, Anna ; Thiel, Gerhard ; Rauh, Oliver (2020)
A Functional K+ Channel from Tetraselmis Virus 1, a Member of the Mimiviridae.
In: Viruses, 12 (10)
doi: 10.3390/v12101107
Artikel, Bibliographie

Murry, Carter R. ; Agarkova, Irina V. ; Ghosh, Jayadri S. ; Fitzgerald, Fiona C. ; Carlson, Roger M. ; Hertel, Brigitte ; Kukovetz, Kerri ; Rauh, Oliver ; Thiel, Gerhard ; Etten, James L. van (2020)
Genetic Diversity of Potassium Ion Channel Proteins Encoded by Chloroviruses That Infect Chlorella heliozoae.
In: Viruses, 12 (6)
doi: 10.3390/v12060678
Artikel, Bibliographie

Kleuter, Marietheres ; Thiel, Gerhard ; Rauh, Oliver (2020)
Asymmetric Mutations in Selectivity Filter of K+ Channel Pore Generate C-type Inactivation.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.1030
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2020)
Camp-Induced Conformational Changes in the C-Linker of HCN4.
In: Biophysical Journal, 118 (3)
doi: 10.1016/j.bpj.2019.11.2365
Artikel, Bibliographie

Eckert, Denise ; Schulze, Tobias ; Stahl, Julian ; Rauh, Oliver ; Etten, James L. van ; Hertel, Brigitte ; Schroeder, Indra ; Moroni, Anna ; Thiel, Gerhard (2019)
A small viral potassium ion channel with an inherent inward rectification.
In: Channels (Austin, Tex.), 13 (1)
Artikel, Bibliographie

Introini, Bianca ; Saponaro, Andrea ; Bonucci, Alessio ; Rauh, Oliver ; Cantini, Francesca ; Banci, Lucia ; Thiel, Gerhard ; Moroni, Anna (2019)
Chimeric HCN Channels for Studying Camp-Induced Conformational Changes in the C-Linker.
In: Biophysical Journal, 116 (3)
doi: 10.1016/j.bpj.2018.11.1631
Artikel, Bibliographie

Winterstein, Laura-Marie ; Kukovetz, Kerri ; Rauh, Oliver ; Turman, Daniel L. ; Braun, Christian ; Moroni, Anna ; Schroeder, Indra ; Thiel, Gerhard (2018)
Reconstitution and functional characterization of ion channels from nanodiscs in lipid bilayers.
In: The Journal of general physiology, 150 (4)
Artikel, Bibliographie

Kukovetz, Kerri ; Engel, Anja ; Gutsfeld, Sebastian ; Kithil, Marina ; Rauh, Oliver ; Moroni, Anna ; Thiel, Gerhard (2018)
Codon Usage Influences Gating of Small K+ Channels.
In: Biophysical journal, 114 (3)
Artikel, Bibliographie

Saponaro, Andrea ; Porro, Alessandro ; Chaves-Sanjuan, Antonio ; Nardini, Marco ; Rauh, Oliver ; Thiel, Gerhard ; Moroni, Anna (2017)
Fusicoccin Activates KAT1 Channels by Stabilizing their Interaction with 14-3-3- Proteins.
In: The Plant cell, 29 (10)
Artikel, Bibliographie

Voos, Patrick ; Yazar, Mehtap ; Lautenschläger, René ; Rauh, Oliver ; Moroni, Anna ; Thiel, Gerhard (2017)
The small neurotoxin apamin blocks not only small conductance Ca(2+) activated K(+) channels (SK type) but also the voltage dependent Kv1.3 channel.
In: European biophysics journal : EBJ, 46 (6)
Artikel, Bibliographie

Rauh, Oliver ; Urban, Martin ; Henkes, Leonhard M. ; Winterstein, Tobias ; Greiner, Timo ; Etten, James L. van ; Moroni, Anna ; Kast, Stefan M. ; Thiel, Gerhard ; Schroeder, Indra (2017)
Identification of Intrahelical Bifurcated H-Bonds as a New Type of Gate in K(+) Channels.
In: Journal of the American Chemical Society, 139 (22)
Artikel, Bibliographie

Rauh, Oliver ; Hansen, Ulf-Peter ; Mach, Sebastian ; Hartel, Andreas J. W. ; Shepard, Kenneth L. ; Thiel, Gerhard ; Schroeder, Indra (2017)
Extended beta distributions open the access to fast gating in bilayer experiments-assigning the voltage-dependent gating to the selectivity filter.
In: FEBS Letters, 591 (23)
doi: 10.1002/1873-3468.12898
Artikel, Bibliographie

Hansen, Ulf-Peter ; Rauh, Oliver ; Schroeder, Indra (2016)
A simple recipe for setting up the flux equations of cyclic and linear reaction schemes of ion transport with a high number of states: The arrow scheme.
In: Channels, 10 (2)
doi: 10.1080/19336950.2015.1120391
Artikel, Bibliographie

Siotto, Fenja ; Martin, Corinna ; Rauh, Oliver ; Etten, James L. van ; Schroeder, Indra ; Moroni, Anna ; Thiel, Gerhard (2014)
Viruses infecting marine picoplancton encode functional potassium ion channels.
In: Virology, 466-467
Artikel, Bibliographie

Dissertation

Rauh, Oliver (2018)
Molecular explanations for gating in simple model K+ channels.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung