2023

Bogen, Jan Patrick ; Carrara, Stefania Candela ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Supplemental information with antibody sequences.
doi: 10.26083/tuprints-00017895
Anderes, Erstveröffentlichung, Verlagsversion

Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 14
doi: 10.3389/fimmu.2023.1170042
Artikel, Bibliographie

2022

Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.888838
Artikel, Bibliographie

Fibing, David ; Bogen, Jan P. ; Carrara, Stefania C. ; Deweid, Lukas ; Zielonka, Stefan ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells.
In: Frontiers in Bioengineering and Biotechnology, 10
doi: 10.3389/fbioe.2022.794389
Artikel, Bibliographie

Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Targeted phagocytosis induction for cancer immunotherapy via bispecific MerTK-engaging antibodies.
In: International Journal of Molecular Sciences, 23 (24)
doi: 10.3390/ijms232415673
Artikel, Bibliographie

Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.1051875
Artikel, Bibliographie

2021

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.669496
Artikel, Bibliographie

Elter, Adrian ; Bogen, Jan P. ; Hinz, Steffen C. ; Fiebig, David ; Macarrón Palacios, Arturo ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Humanization of chicken‐derived scFv using yeast surface display and NGS data mining.
In: Biotechnology Journal : Systems & Synthetic Biology, Nanobiotech, Medicine, 16 (3)
doi: 10.1002/biot.202000231
Artikel, Bibliographie

Carrara, Stefania C. ; Fiebig, David ; Bogen, Jan P. ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Recombinant antibody production using a dual-promoter single plasmid system.
In: Antibodies, 10 (2)
doi: 10.3390/antib10020018
Artikel, Bibliographie

Bogen, Jan Patrick ; Grzeschik, Julius ; Jakobsen, Jørn ; Bähre, Alexandra ; Hock, Björn ; Kolmar, Harald (2021)
Treating Bladder Cancer: Engineering of Current and Next Generation Antibody-, Fusion Protein-, mRNA-, Cell- and Viral-Based Therapeutics.
In: Frontiers in Oncology, 11
doi: 10.3389/fonc.2021.672262
Artikel, Bibliographie

2020

Macarrón Palacios, Arturo ; Grzeschik, Julius ; Deweid, Lukas ; Krah, Simon ; Zielonka, Stefan ; Rösner, Thies ; Peipp, Matthias ; Valerius, Thomas ; Kolmar, Harald (2020)
Specific targeting of lymphoma cells using semisynthetic anti-idiotype shark antibodies.
In: Frontiers in Immunology, 11
doi: 10.3389/fimmu.2020.560244
Artikel, Bibliographie

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2020)
Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening.
In: Frontiers in Immunology, 11
doi: 10.3389/fimmu.2020.606878
Artikel, Bibliographie

Bogen, Jan P. ; Storka, Juliana ; Yanakieva, Desislava ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2020)
Isolation of common light chain antibodies from immunized chickens using yeast biopanning and fluorescence‐activated cell sorting.
In: Biotechnology Journal : Systems and Synthetic Biology, Nanobiotech, Medicine, 16 (3)
doi: 10.1002/biot.202000240
Artikel, Bibliographie

2019

Bogen, Jan P. ; Hinz, Steffen C. ; Grzeschik, Julius ; Ebenig, Aileen ; Krah, Simon ; Zielonka, Stefan ; Kolmar, Harald (2019)
Dual function pH responsive bispecific antibodies for tumor targeting and antigen depletion in plasma.
In: Frontiers in Immunology, 10
doi: 10.3389/fimmu.2019.01892
Artikel, Bibliographie

Grzeschik, Julius (2019)
Enabling technologies for the generation of high-affinity binders based on immunoglobulin scaffolds.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

2017

Könning, Doreen ; Rhiel, Laura ; Empting, Martin ; Grzeschik, Julius ; Sellmann, Carolin ; Schröter, Christian ; Zielonka, Stefan ; Dickgießer, Stephan ; Pirzer, Thomas ; Yanakieva, Desislava ; Becker, Stefan ; Kolmar, Harald (2017)
Semi-synthetic vNAR libraries screened against therapeutic antibodies primarily deliver anti-idiotypic binders.
In: Scientific Reports, 7 (1)
doi: 10.1038/s41598-017-10513-9
Artikel, Bibliographie

2014

Hofmeyer, Thomas ; Bulani, Siyavuya Ishmael ; Grzeschik, Julius ; Krah, Simon ; Glotzbach, Bernhard ; Uth, Christina ; Avrutina, Olga ; Brecht, Michael ; Göringer, H. Ulrich ; van Zyl, Petrus ; Kolmar, Harald (2014)
Protein Production in Yarrowia lipolytica Via Fusion to the Secreted Lipase Lip2p.
In: Molecular biotechnology, 56 (1)
Artikel, Bibliographie