2021

Kaiser, Christoph ; Schneider, Jeannine ; Groher, Florian ; Suess, Beatrix ; Wachtveitl, Josef (2021)
What defines a synthetic riboswitch? - Conformational dynamics of ciprofloxacin aptamers with similar binding affinities but varying regulatory potentials.
In: Nucleic acids research, 49 (7)
doi: 10.1093/nar/gkab166
Artikel, Bibliographie

2020

Schmidt, Michael ; Hamacher, Kay ; Reinhardt, Felix ; Lotz, Thea S. ; Groher, Florian ; Suess, Beatrix ; Jager, Sven (2020)
SICOR: Subgraph Isomorphism Comparison of RNA Secondary Structures.
In: IEEE/ACM Transactions on Computational Biology and Bioinformatics, 17 (6)
doi: 10.1109/TCBB.2019.2926711
Artikel, Bibliographie

Grau, Florian C. ; Jaeger, Jeannine ; Groher, Florian ; Suess, Beatrix ; Muller, Yves A. (2020)
The complex formed between a synthetic RNA aptamer and the transcription repressor TetR is a structural and functional twin of the operator DNA-TetR regulator complex.
In: Nucleic acids research, 48 (6)
doi: 10.1093/nar/gkaa083
Artikel, Bibliographie

2019

Mol, Adam A. ; Groher, Florian ; Schreiber, Britta ; Rühmkorff, Ciaran ; Suess, Beatrix (2019)
Robust gene expression control in human cells with a novel universal TetR aptamer splicing module.
In: Nucleic acids research, 47 (20)
doi: 10.1093/nar/gkz753
Artikel, Bibliographie

Boussebayle, Adrien ; Torka, Daniel ; Ollivaud, Sandra ; Braun, Johannes ; Bofill-Bosch, Cristina ; Dombrowski, Max ; Groher, Florian ; Hamacher, Kay ; Suess, Beatrix (2019)
Next-level riboswitch development-implementation of Capture-SELEX facilitates identification of a new synthetic riboswitch.
In: Nucleic acids research, 47 (9)
doi: 10.1093/nar/gkz216
Artikel, Bibliographie

Boussebayle, Adrien ; Groher, Florian ; Suess, Beatrix (2019)
RNA-based Capture-SELEX for the selection of small molecule-binding aptamers.
In: Methods (San Diego, Calif.), 161
doi: 10.1016/j.ymeth.2019.04.004
Artikel, Bibliographie

Lotz, Thea S. ; Halbritter, Thomas ; Kaiser, Christoph ; Rudolph, Martin M. ; Kraus, Leon ; Groher, Florian ; Steinwand, Sabrina ; Wachtveitl, Josef ; Heckel, Alexander ; Suess, Beatrix (2019)
A light-responsive RNA aptamer for an azobenzene derivative.
In: Nucleic acids research, 47 (4)
doi: 10.1093/nar/gky1225
Artikel, Bibliographie

Jaeger, Jeannine ; Groher, Florian ; Stamm, Jacqueline ; Spiehl, Dieter ; Braun, Johannes ; Dörsam, Edgar ; Suess, Beatrix (2019)
Characterization and Inkjet Printing of an RNA Aptamer for Paper-Based Biosensing of Ciprofloxacin.
In: Biosensors, 9 (1)
doi: 10.3390/bios9010007
Artikel, Bibliographie

Groher, Ann-Christin ; Jager, Sven ; Schneider, Christopher ; Groher, Florian ; Hamacher, Kay ; Suess, Beatrix (2019)
Tuning the Performance of Synthetic Riboswitches using Machine Learning.
In: ACS Synthetic Biology, 8 (1)
doi: 10.1021/acssynbio.8b00207
Artikel, Bibliographie

Stamm, Jacqueline ; Spiehl, Dieter ; Jaeger, Jeannine ; Groher, Florian ; Meckel, Tobias ; Suess, Beatrix ; Dörsam, Edgar (2019)
A test system for the printing of functional nucleic acids onto different carriers and verification of its functionality by DNA dyes.
In: Journal of Print and Media Technology Research, 8 (1)
doi: 10.14622/JPMTR-1821
Artikel, Bibliographie

2018

Jaeger, Jeannine ; Stamm, Jacqueline ; Spiehl, Dieter ; Groher, Florian ; Braun, Johannes ; Dörsam, Edgar ; Suess, Beatrix (2018)
Druckbare Biosensoren - Ein RNA basiertes Nachweissystem auf Papier. (Poster).
2. Tag der Interdisziplinarität, Forum für interdisziplinäre Forschung. Darmstadt (05.11.2018-05.11.2018)
Konferenzveröffentlichung, Bibliographie

Stamm, Jacqueline ; Spiehl, Dieter ; Jaeger, Jeannine ; Groher, Florian ; Meckel, Tobias ; Suess, Beatrix ; Dörsam, Edgar (2018)
DNA and DNA staining as a test system for the development of an aptamer-based biosensor for sensing of antibiotics.
45th International Research Conference of IARIGAI. Warsaw, Poland (03.10.2018-07.10.2018)
Konferenzveröffentlichung, Bibliographie

Groher, Florian ; Bofill-Bosch, Cristina ; Schneider, Christopher ; Braun, Johannes ; Jager, Sven ; Geißler, Katharina ; Hamacher, Kay ; Suess, Beatrix (2018)
Riboswitching with ciprofloxacin-development and characterization of a novel RNA regulator.
In: Nucleic acids research, 46 (4)
Artikel, Bibliographie

2017

Atanasov, Janina ; Groher, Florian ; Weigand, Julia E. ; Suess, Beatrix (2017)
Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals.
In: Nucleic acids research, 45 (22)
doi: 10.1093/nar/gkx858
Artikel, Bibliographie

Saul, Meike J. ; Groher, Florian ; Hegewald, Anett B. ; Müller-McNicoll, Michaela ; Marschalek, Rolf ; Suess, Beatrix ; Steinhilber, Dieter (2017)
TGFβ/SMAD signalling modulates MLL and MLL-AF4 mediated 5-lipoxygenase promoter activation.
In: Prostaglandins & other lipid mediators, 133
Artikel, Bibliographie

2016

Groher, Florian ; Suess, Beatrix (2016)
In vitro selection of antibiotic-binding aptamers.
In: Methods (San Diego, Calif.), 106
Artikel, Bibliographie

Groher, Florian (2016)
Kontrolle des prä-mRNA Spleißens durch synthetische Riboswitche.
Technische Universität Darmstadt
Dissertation, Erstveröffentlichung

2015

Berens, Christian ; Groher, Florian ; Suess, Beatrix (2015)
RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expression.
In: Biotechnology journal, 10 (2)
Artikel, Bibliographie

Özçoban, Cem ; Halbritter, Thomas ; Steinwand, Sabrina ; Herzig, Lisa-Marie ; Kohl-Landgraf, Jörg ; Askari, Noushin ; Groher, Florian ; Fürtig, Boris ; Richter, Christian ; Schwalbe, Harald ; Suess, Beatrix ; Wachtveitl, Josef ; Heckel, Alexander (2015)
Water-Soluble Py-BIPS Spiropyrans as Photoswitches for Biological Applications.
In: Organic letters, 17 (6)
Artikel, Bibliographie

2014

Gottstein-Schmidtke, Sina R. ; Duchardt-Ferner, Elke ; Groher, Florian ; Weigand, Julia E. ; Gottstein, Daniel ; Suess, Beatrix ; Wöhnert, Jens (2014)
Building a stable RNA U-turn with a protonated cytidine.
In: RNA (New York, N.Y.), 20 (8)
Artikel, Bibliographie

Weigand, Julia E. ; Gottstein-Schmidtke, Sina R. ; Demolli, Shemsi ; Groher, Florian ; Duchardt-Ferner, Elke ; Wöhnert, Jens ; Suess, Beatrix (2014)
Sequence Elements Distal to the Ligand Binding Pocket Modulate the Efficiency of a Synthetic Riboswitch.
In: Chembiochem : a European journal of chemical biology, 15 (11)
Artikel, Bibliographie

Groher, Florian ; Suess, Beatrix (2014)
Synthetic riboswitches - A tool comes of age.
In: Biochimica et biophysica acta - Gene regulation mechanisms, 1839 (10)
Artikel, Bibliographie