2024

Grotz, Melanie ; Gijzel, Lieke van ; Bitsch, Peter ; Carrara, Stefania C. ; Kolmar, Harald ; Garg, Sakshi (2024)
Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model.
In: Frontiers in Drug Discovery, 4
doi: 10.3389/fddsv.2024.1427407
Artikel, Bibliographie

2023

Carrara, Stefania C. (2023)
Generation of Multispecific Antibodies with Immune Cell Modulating Functions.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023023
Dissertation, Erstveröffentlichung, Verlagsversion

Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 14
doi: 10.3389/fimmu.2023.1170042
Artikel, Bibliographie

2022

Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.888838
Artikel, Bibliographie

Fibing, David ; Bogen, Jan P. ; Carrara, Stefania C. ; Deweid, Lukas ; Zielonka, Stefan ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells.
In: Frontiers in Bioengineering and Biotechnology, 10
doi: 10.3389/fbioe.2022.794389
Artikel, Bibliographie

Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Targeted phagocytosis induction for cancer immunotherapy via bispecific MerTK-engaging antibodies.
In: International Journal of Molecular Sciences, 23 (24)
doi: 10.3390/ijms232415673
Artikel, Bibliographie

Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.1051875
Artikel, Bibliographie

2021

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.669496
Artikel, Bibliographie

Pekar, Lukas ; Klewinghaus, Daniel ; Arras, Paul ; Carrara, Stefania C. ; Harwardt, Julia ; Krah, Simon ; Yanakieva, Desislava ; Toleikis, Lars ; Smider, Vaughn V. ; Kolmar, Harald ; Zielonka, Stefan (2021)
Milking the cow: cattle-derived chimeric ultralong CDR-H3 antibodies and their engineered CDR-H3-only knobbody counterparts targeting epidermal growth factor receptor elicit potent NK cell-mediated cytotoxicity.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.742418
Artikel, Bibliographie

Carrara, Stefania C. ; Fiebig, David ; Bogen, Jan P. ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Recombinant antibody production using a dual-promoter single plasmid system.
In: Antibodies, 10 (2)
doi: 10.3390/antib10020018
Artikel, Bibliographie

2020

Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2020)
Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening.
In: Frontiers in Immunology, 11
doi: 10.3389/fimmu.2020.606878
Artikel, Bibliographie