2024

Kubaczka, Erik ; Gehringer, Maximilian ; Marlhens, Jérémie J. M. ; Schwarz, Tobias ; Molderings, Maik ; Engelmann, Nicolai ; Garcia, Hernan G. ; Hochberger, Christian ; Koeppl, Heinz (2024)
Energy Aware Technology Mapping of Genetic Logic Circuits.
In: ACS Synthetic Biology, 13 (10)
doi: 10.1021/acssynbio.4c00395
Artikel, Bibliographie

Suleiman, Dario ; Zoll, Thomas ; Eiermann, Aron ; Spiehl, Dieter ; Dörsam, Edgar ; Kabisch, Johannes (2024)
Skynet: low-cost, laser guided loading assistance for life science robotic platforms.
In: TechRxiv
doi: 10.36227/techrxiv.172720421.12920033/v1
Artikel, Bibliographie

Pfeifer Serrahima, Jordi ; Schoenfeld, Katrin ; Kühnel, Ines ; Harwardt, Julia ; Macarrón Palacios, Arturo ; Prüfer, Maren ; Kolaric, Margareta ; Oberoi, Pranav ; Kolmar, Harald ; Wels, Winfried S. (2024)
Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies.
In: Frontiers in Immunology, 15
doi: 10.3389/fimmu.2024.1457887
Artikel, Bibliographie

Thiem, Daniel B. ; Szabo, Greta ; Burg, Thomas P. (2024)
Model-Based Optimization of Solid-Supported Micro-Hotplates for Microfluidic Cryofixation.
In: Micromachines, (9)
doi: 10.3390/mi15091069
Artikel, Bibliographie

Grotz, Melanie ; Gijzel, Lieke van ; Bitsch, Peter ; Carrara, Stefania C. ; Kolmar, Harald ; Garg, Sakshi (2024)
Mimicking the immunosuppressive impact of fibroblasts in a 3D multicellular spheroid model.
In: Frontiers in Drug Discovery, 4
doi: 10.3389/fddsv.2024.1427407
Artikel, Bibliographie

Ulitzka, Michael ; Harwardt, Julia ; Lipinski, Britta ; Tran, Hue ; Hock, Björn ; Kolmar, Harald (2024)
Potent apoptosis induction by a novel trispecific B7-H3xCD16xTIGIT 2+1 common light chain natural killer cell engager.
In: Molecules, 29 (5)
doi: 10.3390/molecules29051140
Artikel, Bibliographie

Zhou, Xueyuan ; Geyer, Felix Klaus ; Happel, Dominic ; Takimoto, Jeffrey ; Kolmar, Harald ; Rabinovich, Brian (2024)
Using protein geometry to optimize cytotoxicity and the cytokine window of a ROR1 specific T cell engager.
In: Frontiers in Immunology, 15
doi: 10.3389/fimmu.2024.1323049
Artikel, Bibliographie

Kramat, Janice ; Kraus, Leon ; Gunawan, Vincent J. ; Smyej, Elias ; Froehlich, Philipp ; Weber, Tim E. ; Spiehl, Dieter ; Koeppl, Heinz ; Blaeser, Andreas ; Suess, Beatrix (2024)
Sensing levofloxacin with an RNA aptamer as a bioreceptor.
In: Biosensors, 14 (1)
doi: 10.3390/bios14010056
Artikel, Bibliographie

Geiger, Thomas M. ; Walz, Michael ; Meyners, Christian ; Kuehn, Angela ; Dreizler, Johannes K. ; Sugiarto, Wisely O. ; Maciel, Edvaldo V. S. ; Zheng, Min ; Lermyte, Frederik ; Hausch, Felix (2024)
Discovery of a potent proteolysis targeting chimera enables targeting the scaffolding functions of FK506‐binding protein 51 (FKBP51).
In: Angewandte Chemie International Edition, 63 (3)
doi: 10.1002/anie.202309706
Artikel, Bibliographie

Fritschen, Anna ; Lindner, Nils ; Scholpp, Sebastian ; Richthof, Philipp ; Dietz, Jonas ; Linke, Philipp ; Guttenberg, Zeno ; Blaeser, Andreas (2024)
High-scale 3D-bioprinting platform for the automated production of vascularized organs-on-a-chip.
In: Advanced Healthcare Materials, 13 (17)
doi: 10.1002/adhm.202304028
Artikel, Bibliographie

Nuber, Ulrike A. (2024)
The fabrication-assembly challenge in tissue engineering.
In: at - Automatisierungstechnik, 72 (7)
doi: 10.1515/auto-2024-0024
Artikel, Bibliographie

Kelvin, Daniel ; Suess, Beatrix (2024)
RNA aptamers: promising tools in synthetic biology.
In: at - Automatisierungstechnik, 72 (7)
doi: 10.1515/auto-2024-0002
Artikel, Bibliographie

Lindner, Nils ; Mejia-Wille, Andres ; Fritschen, Anna ; Blaeser, Andreas (2024)
Development of a robotic-assisted handling and manipulation system for the high-scale bioproduction of 3D-bioprinted organ-on-a-chip devices.
In: HardwareX, 19
doi: 10.1016/j.ohx.2024.e00572
Artikel, Bibliographie

2023

Belluati, Andrea ; Harley, Iain ; Lieberwirth, Ingo ; Bruns, Nico (2023)
An outer membrane‐inspired polymer coating protects and endows Escherichia coli with novel functionalities.
In: Small : nano micro, 19 (46)
doi: 10.1002/smll.202303384
Artikel, Bibliographie

Deutscher, Robin C. E. ; Safa Karagöz, M. ; Purder, Patrick L. ; Kolos, Jürgen M. ; Meyners, Christian ; Oki Sugiarto, Wisely ; Krajczy, Patryk ; Tebbe, Frederike ; Geiger, Thomas M. ; Ünal, Can ; Hellmich, Ute A. ; Steinert, Michael ; Hausch, Felix (2023)
[4.3.1]Bicyclic FKBP ligands inhibit Legionella Pneumophila infection by LpMip‐dependent and LpMip‐independent mechanisms.
In: ChemBioChem, 24 (21)
doi: 10.1002/cbic.202300442
Artikel, Bibliographie

Mathony, Jan ; Aschenbrenner, Sabine ; Becker, Philipp ; Niopek, Dominik (2023)
Dissecting the Determinants of Domain Insertion Tolerance and Allostery in Proteins.
In: Advanced Science, 10 (28)
doi: 10.1002/advs.202303496
Artikel, Bibliographie

Klein, Thomas ; Funke, Franziska ; Rossbach, Oliver ; Lehmann, Gerhard ; Vockenhuber, Michael ; Medenbach, Jan ; Suess, Beatrix ; Meister, Gunter ; Babinger, Patrick (2023)
Investigating the Prevalence of RNA-Binding Metabolic Enzymes in E. coli.
In: International Journal of Molecular Sciences, 24 (14)
doi: 10.3390/ijms241411536
Artikel, Bibliographie

Engelmann, Nicolai ; Schwarz, Tobias ; Kubaczka, Erik ; Hochberger, Christian ; Koeppl, Heinz (2023)
Context-Aware Technology Mapping in Genetic Design Automation.
In: ACS Synthetic Biology, 12 (2)
doi: 10.1021/acssynbio.2c00361
Artikel, Bibliographie

Mathony, Jan (2023)
Engineering Proteins by Domain Insertion.
Technische Universität Darmstadt
doi: 10.26083/tuprints-00023638
Dissertation, Erstveröffentlichung, Verlagsversion

Bitsch, Peter ; Baum, Eva S. ; Beltrán Hernández, Irati ; Bitsch, Sebastian Harald ; Harwood, Jakob ; Oliveira, Sabrina ; Kolmar, Harald (2023)
Penetration of nanobody-dextran polymer conjugates through tumor spheroids.
In: Pharmaceutics, 15 (10)
doi: 10.3390/pharmaceutics15102374
Artikel, Bibliographie

Russell, Sam ; Bruns, Nico (2023)
Encapsulation of fragrances in micro‐ and nano‐capsules, polymeric micelles, and polymersomes.
In: Macromolecular Rapid Communications, 44 (16)
doi: 10.1002/marc.202300120
Artikel, Bibliographie

Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 14
doi: 10.3389/fimmu.2023.1170042
Artikel, Bibliographie

Cichos, Simon ; Schätzlein, Eva ; Wiesmann-Imilowski, Nadine ; Blaeser, Andreas ; Henrich, Dirk ; Frank, Johannes ; Drees, Philipp ; Gercek, Erol ; Ritz, Ulrike (2023)
A new 3D-printed polylactic acid-bioglass composite for bone tissue engineering induces angiogenesis in vitro and in ovo.
In: International Journal of Bioprinting, 9 (5)
doi: 10.18063/ijb.751
Artikel, Bibliographie

2022

Fritschen, Anna ; Bell, Alena K. ; Königstein, Inga ; Stühn, Lukas ; Stark, Robert W. ; Blaeser, Andreas (2022)
Investigation and comparison of resin materials in transparent DLP-printing for application in cell culture and organs-on-a-chip.
In: Biomaterials Science, 10 (8)
doi: 10.1039/D1BM01794B
Artikel, Bibliographie

Köhs, Lukas ; Kukovetz, Kerri ; Rauh, Oliver ; Koeppl, Heinz (2022)
Nonparametric Bayesian inference for meta-stable conformational dynamics.
In: Physical Biology, 19 (5)
doi: 10.1088/1478-3975/ac885e
Artikel, Bibliographie

Velasquez, Sara T. R. ; Jang, Daseul ; Jenkins, Peter ; Liu, Peng ; Yang, Liu ; Korley, LaShanda T. J. ; Bruns, Nico (2022)
Peptide‐reinforced amphiphilic polymer conetworks.
In: Advanced Functional Materials, 32 (51)
doi: 10.1002/adfm.202207317
Artikel, Bibliographie

Karakaya, Emine ; Bider, Faina ; Frank, Andreas ; Teßmar, Jörg ; Schöbel, Lisa ; Forster, Leonard ; Schrüfer, Stefan ; Schmidt, Hans-Werner ; Schubert, Dirk Wolfram ; Blaeser, Andreas ; Boccaccini, Aldo R. ; Detsch, Rainer (2022)
Targeted Printing of Cells: Evaluation of ADA-PEG Bioinks for Drop on Demand Approaches.
In: Gels, 8 (4)
doi: 10.3390/gels8040206
Artikel, Bibliographie

Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.888838
Artikel, Bibliographie

Mirdamadi Esfahani, Maleknaz ; Goerlitzer, Eric Sidney Aaron ; Kunz, Ulrike ; Vogel, Nicolas ; Engstler, Joerg ; Andrieu-Brunsen, Annette (2022)
N-Methyl-2-pyrrolidone as a Reaction Medium for Gold(III)-Ion Reduction and Star-like Gold Nanostructure Formation.
In: ACS Omega, 7 (11)
doi: 10.1021/acsomega.1c06835
Artikel, Bibliographie

Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.1051875
Artikel, Bibliographie

Lerma Romero, Jorge A. ; Meyners, Christian ; Christmann, Andreas ; Reinbold, Lisa M. ; Charalampidou, Anna ; Hausch, Felix ; Kolmar, Harald (2022)
Binding pocket stabilization by high-throughput screening of yeast display libraries.
In: Frontiers in Molecular Biosciences, 9
doi: 10.3389/fmolb.2022.1023131
Artikel, Bibliographie

Ali, Ataurehman ; Happel, Dominic ; Habermann, Jan ; Schoenfeld, Katrin ; Macarrón Palacios, Arturo ; Bitsch, Sebastian ; Englert, Simon ; Schneider, Hendrik ; Avrutina, Olga ; Fabritz, Sebastian ; Kolmar, Harald (2022)
Sactipeptide Engineering by Probing the Substrate Tolerance of a Thioether‐Bond‐Forming Sactisynthase.
In: Angewandte Chemie International Edition, 61 (45)
doi: 10.1002/anie.202210883
Artikel, Bibliographie

Ali, Ataurehman ; Happel, Dominic ; Habermann, Jan ; Schoenfeld, Katrin ; Macarrón Palacios, Arturo ; Bitsch, Sebastian ; Englert, Simon ; Schneider, Hendrik ; Avrutina, Olga ; Fabritz, Sebastian ; Kolmar, Harald (2022)
Untersuchungen zur Substrattoleranz von Sactisynthasen für die Generierung Thioether‐verbrückter Sactipeptide mit neuen Eigenschaften.
In: Angewandte Chemie, 134 (45)
doi: 10.1002/ange.202210883
Artikel, Bibliographie

Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Targeted phagocytosis induction for cancer immunotherapy via bispecific MerTK-engaging antibodies.
In: International Journal of Molecular Sciences, 23 (24)
doi: 10.3390/ijms232415673
Artikel, Bibliographie

Hadjabdelhafid-Parisien, Adem ; Bitsch, Sebastian ; Macarrón Palacios, Arturo ; Deweid, Lukas ; Kolmar, Harald ; Pelletier, Joelle N. (2022)
Tag-free, specific conjugation of glycosylated IgG1 antibodies using microbial transglutaminase.
In: RSC Advances, 12 (52)
doi: 10.1039/D2RA05630E
Artikel, Bibliographie

2021

Lehr, François-Xavier ; Kuzembayeva, Alina ; Bailey, Megan E. ; Kleindienst, Werner ; Kabisch, Johannes ; Koeppl, Heinz (2021)
Functionalizing cell-free systems with CRISPR-associated proteins: Application to RNA-based circuit engineering.
In: ACS Synthetic Biology, 10 (9)
doi: 10.1021/acssynbio.0c00386
Artikel, Bibliographie

Ion, Ion Gabriel ; Wildner, C. ; Loukrezis, D. ; Koeppl, H. ; De Gersem, H. (2021)
Tensor-train approximation of the chemical master equation and its application for parameter inference.
In: The Journal of Chemical Physics, 155 (3)
doi: 10.1063/5.0045521
Artikel, Bibliographie

Glinkowska, Monika ; Waldminghaus, Torsten ; Riber, Leise (2021)
Editorial: Bacterial chromosomes under changing environmental conditions.
In: Frontiers in Microbiology, 12
doi: 10.3389/fmicb.2021.633466
Artikel, Bibliographie

Ali, Mubarak ; Nasir, Saima ; Froehlich, Kristina ; Ramirez, Patricio ; Cervera, Javier ; Mafe, Salvador ; Ensinger, Wolfgang (2021)
Size‐Based Cationic Molecular Sieving through Solid‐State Nanochannels.
In: Advanced Materials Interfaces
doi: 10.1002/admi.202001766
Artikel, Bibliographie

Reich, C. ; Prangemeier, T. ; Özdemir, C. ; Koeppl, H. (2021)
OSS-Net: Memory Efficient High Resolution Semantic Segmentation of 3D Medical Data.
32nd British Machine Vision Conference. virtual Conference (22.11.2021-25.11.2021)
Konferenzveröffentlichung, Bibliographie

2020

Li, Yaya ; Rehbock, Christoph ; Nachev, Milen ; Stamm, Jacqueline ; Sures, Bernd ; Blaeser, Andreas ; Barcikowski, Stephan (2020)
Matrix-specific mechanism of Fe ion release from laser-generated 3D-printable nanoparticle-polymer composites and their protein adsorption properties.
In: Nanotechnology, 31 (40)
doi: 10.1088/1361-6528/ab94da
Artikel, Bibliographie

Sinzger, M. ; Gehri, M. ; Koeppl, H. (2020)
Poisson channel with binary Markov input and average sojourn time constraint.
ISIT'20 - International Symposium on Information Theory. virtual online conference (21.06.2020-26.06.2020)
doi: 10.1109/ISIT44484.2020.9174360
Konferenzveröffentlichung, Bibliographie

Sozhamannan, Shanmuga ; Waldminghaus, Torsten (2020)
Exception to the exception rule: synthetic and naturally occurring single chromosome Vibrio cholerae.
In: Environmental Microbiology, 22 (10)
doi: 10.1111/1462-2920.15002
Artikel, Bibliographie

2016

Sulaimanov, Nurgazy ; Koeppl, Heinz (2016)
Graph reconstruction using covariance-based methods.
In: EURASIP Journal on Bioinformatics and Systems Biology
doi: 10.1186/s13637-016-0052-y
Artikel, Bibliographie