Noon, Angela T. ; Shibata, A. ; Rief, N. ; Löbrich, M. ; Stewart, G. S. ; Jeggo, P. A. ; Goodarzi, A. A. (2010)
53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
In: Nature Cell Biology, 12 (2)
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Beucher, A. ; Birraux, J. ; Tchouandong, L. ; Barton, O. ; Shibata, A. ; Conrad, S. ; Goodarzi, A. A. ; Krempler, A. ; Jeggo, P. A. ; Löbrich, M. (2009)
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2.
In: EMBO Journal, 28 (21)
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Goodarzi, A. A. ; Noon, A. ; Deckbar, D. ; Ziv, Y. ; Shiloh, Y. ; Löbrich, M. ; Jeggo, P. A. (2008)
ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin.
In: Molecular Cell, 31 (2)
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Jeggo, P. A. ; Löbrich, M. (2007)
DNA double-strand breaks: their cellular and clinical impact?
In: Oncogene, 26 (56)
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Kegel, P. ; Riballo, E. ; Kühne, M. ; Jeggo, P. A. ; Löbrich, M. (2007)
X-irradiation of cells on glass slides has a dose doubling impact.
In: DNA Repair, 6 (11)
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Löbrich, M. ; Jeggo, P. A. (2007)
The impact of a negligent G2/M checkpoint on genomic instability and cancer induction.
In: Nature Reviews Cancer, 7 (11)
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Krempler, A. ; Deckbar, D. ; Jeggo, P. A. ; Löbrich, M. (2007)
An imperfect G2M checkpoint contributes to chromosome instability following irradiation of S and G2 phase cells.
In: Cell Cycle, 6 (14)
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Deckbar, D. ; Birraux, J. ; Krempler, A. ; Tchouandong, L. ; Beucher, A. ; Walker, S. ; Stiff, T. ; Jeggo, P. A. ; Löbrich, M. (2007)
Chromosome breakage after G2 checkpoint release.
In: Journal of Cell Biology, 176 (6)
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Jeggo, P. A. ; Löbrich, M. (2006)
Contribution of DNA repair and cell cycle checkpoint arrest to the maintenance of genomic stability.
In: DNA Repair, 5 (9-10)
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Jeggo, P. A. ; Löbrich, M. (2006)
Radiation-induced DNA damage responses.
In: Radiation Protection Dosimetry, 122 (1-4)
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Löbrich, M. ; Jeggo, P. A. (2005)
The two edges of the ATM sword: co-operation between repair and checkpoint functions.
In: Radiotherapy and Oncology, 76 (2)
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Löbrich, M. ; Jeggo, P. A. (2005)
Harmonising the response to DSBs: a new string in the ATM bow.
In: DNA Repair, 4 (7)
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Jeggo, P. A. ; Löbrich, M. (2005)
Artemis links ATM to double strand break rejoining.
In: Cell Cycle, 4 (3)
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Riballo, E. ; Kühne, M. ; Rief, N. ; Doherty, A. ; Smith, G. C. M. ; Recio, M. J. ; Reis, C. ; Dahm, K. ; Fricke, A. ; Krempler, A. ; Parker, A. R. ; Jackson, S. P. ; Gennery, A. ; Jeggo, P. A. ; Löbrich, M. (2004)
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.
In: Molecular Cell, 16 (5)
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Stiff, T. ; O'Driscoll, M. ; Rief, N. ; Iwabuchi, K. ; Löbrich, M. ; Jeggo, P. A. (2004)
ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation.
In: Cancer Research, 64 (7)
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Kühne, M. ; Riballo, E. ; Rief, N. ; Rothkamm, K. ; Jeggo, P. A. ; Löbrich, M. (2004)
A double-strand break repair defect in ATM-deficient cells contributes to radiosensitivity.
In: Cancer Research, 64 (2)
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Rothkamm, K. ; Kühne, M. ; Jeggo, P. A. ; Löbrich, M. (2001)
Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks.
In: Cancer Research, 61 (10)
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