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Ulitzka, Michael ; Harwardt, Julia ; Lipinski, Britta ; Tran, Hue ; Hock, Björn ; Kolmar, Harald (2024)
Potent apoptosis induction by a novel trispecific B7-H3xCD16xTIGIT 2+1 common light chain natural killer cell engager.
In: Molecules, 29 (5)
doi: 10.3390/molecules29051140
Article, Bibliographie
Bogen, Jan Patrick ; Carrara, Stefania Candela ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Supplemental information with antibody sequences.
doi: 10.26083/tuprints-00017895
Other, Primary publication, Publisher's Version
Harwardt, Julia ; Carrara, Stefania C. ; Bogen, Jan P. ; Schoenfeld, Katrin ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2023)
Generation of a symmetrical trispecific NK cell engager based on a two-in-one antibody.
In: Frontiers in Immunology, 14
doi: 10.3389/fimmu.2023.1170042
Article, Bibliographie
Oliviero, Claudia ; Hinz, Steffen C. ; Bogen, Jan P. ; Kornmann, Henri ; Hock, Björn ; Kolmar, Harald ; Hagens, Gerrit (2022)
Generation of a host cell line containing a MAR-rich landing pad for site-specific integration and expression of transgenes.
In: Biotechnology Progress, 38 (4)
doi: 10.1002/btpr.3254
Article, Bibliographie
Harwardt, Julia ; Bogen, Jan P. ; Carrara, Stefania C. ; Ulitzka, Michael ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.888838
Article, Bibliographie
Fibing, David ; Bogen, Jan P. ; Carrara, Stefania C. ; Deweid, Lukas ; Zielonka, Stefan ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Streamlining the Transition From Yeast Surface Display of Antibody Fragment Immune Libraries to the Production as IgG Format in Mammalian Cells.
In: Frontiers in Bioengineering and Biotechnology, 10
doi: 10.3389/fbioe.2022.794389
Article, Bibliographie
Carrara, Stefania C. ; Bogen, Jan P. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
Targeted phagocytosis induction for cancer immunotherapy via bispecific MerTK-engaging antibodies.
In: International Journal of Molecular Sciences, 23 (24)
doi: 10.3390/ijms232415673
Article, Bibliographie
Carrara, Stefania C. ; Harwardt, Julia ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2022)
TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome.
In: Frontiers in Immunology, 13
doi: 10.3389/fimmu.2022.1051875
Article, Bibliographie
Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Design of a Trispecific Checkpoint Inhibitor and Natural Killer Cell Engager Based on a 2 + 1 Common Light Chain Antibody Architecture.
In: Frontiers in Immunology, 12
doi: 10.3389/fimmu.2021.669496
Article, Bibliographie
Elter, Adrian ; Bogen, Jan P. ; Hinz, Steffen C. ; Fiebig, David ; Macarrón Palacios, Arturo ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Humanization of chicken‐derived scFv using yeast surface display and NGS data mining.
In: Biotechnology Journal : Systems & Synthetic Biology, Nanobiotech, Medicine, 16 (3)
doi: 10.1002/biot.202000231
Article, Bibliographie
Carrara, Stefania C. ; Fiebig, David ; Bogen, Jan P. ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2021)
Recombinant antibody production using a dual-promoter single plasmid system.
In: Antibodies, 10 (2)
doi: 10.3390/antib10020018
Article, Bibliographie
Bogen, Jan Patrick ; Grzeschik, Julius ; Jakobsen, Jørn ; Bähre, Alexandra ; Hock, Björn ; Kolmar, Harald (2021)
Treating Bladder Cancer: Engineering of Current and Next Generation Antibody-, Fusion Protein-, mRNA-, Cell- and Viral-Based Therapeutics.
In: Frontiers in Oncology, 11
doi: 10.3389/fonc.2021.672262
Article, Bibliographie
Bogen, Jan P. ; Carrara, Stefania C. ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2020)
Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening.
In: Frontiers in Immunology, 11
doi: 10.3389/fimmu.2020.606878
Article, Bibliographie
Bogen, Jan P. ; Storka, Juliana ; Yanakieva, Desislava ; Fiebig, David ; Grzeschik, Julius ; Hock, Björn ; Kolmar, Harald (2020)
Isolation of common light chain antibodies from immunized chickens using yeast biopanning and fluorescence‐activated cell sorting.
In: Biotechnology Journal : Systems and Synthetic Biology, Nanobiotech, Medicine, 16 (3)
doi: 10.1002/biot.202000240
Article, Bibliographie
Schröter, Christian ; Becker, Jan ; Krah, Simon ; Zielonka, Stefan ; Doerner, Achim ; Rhiel, Laura ; Günther, Ralf ; Toleikis, Lars ; Kolmar, Harald ; Hock, Björn ; Becker, Stefan (2018)
Selection of antibodies with tailored properties by application of high-throughput multiparameter fluorescence-activated cell sorting of yeast-displayed immune libraries.
In: Molecular Biotechnology, 60
doi: 10.1007/s12033-018-0109-0
Article, Bibliographie
Hock, Björn (2017)
Engineering of monoclonal antibodies and other modalities of potential therapeutic relevance.
Habilitation, Bibliographie
Rhiel, Laura ; Krah, Simon ; Günther, Ralf ; Becker, Stefan ; Kolmar, Harald ; Hock, Björn (2014)
REAL-select: full-length antibody display and library screening by surface capture on yeast cells.
In: PLOS ONE, 9 (12)
doi: 10.1371/journal.pone.0114887
Article, Bibliographie