Cai, Weidong ; Warren, Stacie L. ; Duberg, Katherine ; Yu, Angela ; Hinshaw, Stephen P. ; Menon, Vinod (2023)
Both reactive and proactive control are deficient in children with ADHD and predictive of clinical symptoms.
In: Translational Psychiatry, 13
doi: 10.1038/s41398-023-02471-w
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Cognitive control deficits are a hallmark of attention deficit hyperactivity disorder (ADHD) in children. Theoretical models posit that cognitive control involves reactive and proactive control processes but their distinct roles and inter-relations in ADHD are not known, and the contributions of proactive control remain vastly understudied. Here, we investigate the dynamic dual cognitive control mechanisms associated with both proactive and reactive control in 50 children with ADHD (16F/34M) and 30 typically developing (TD) children (14F/16M) aged 9-12 years across two different cognitive controls tasks using a within-subject design. We found that while TD children were capable of proactively adapting their response strategies, children with ADHD demonstrated significant deficits in implementing proactive control strategies associated with error monitoring and trial history. Children with ADHD also showed weaker reactive control than TD children, and this finding was replicated across tasks. Furthermore, while proactive and reactive control functions were correlated in TD children, such coordination between the cognitive control mechanisms was not present in children with ADHD. Finally, both reactive and proactive control functions were associated with behavioral problems in ADHD, and multi-dimensional features derived from the dynamic dual cognitive control framework predicted inattention and hyperactivity/impulsivity clinical symptoms. Our findings demonstrate that ADHD in children is characterized by deficits in both proactive and reactive control, and suggest that multi-componential cognitive control measures can serve as robust predictors of clinical symptoms.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2023 |
| Autor(en): | Cai, Weidong ; Warren, Stacie L. ; Duberg, Katherine ; Yu, Angela ; Hinshaw, Stephen P. ; Menon, Vinod |
| Art des Eintrags: | Bibliographie |
| Titel: | Both reactive and proactive control are deficient in children with ADHD and predictive of clinical symptoms |
| Sprache: | Englisch |
| Publikationsjahr: | Mai 2023 |
| Ort: | London |
| Verlag: | Nature Publishing Group |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Translational Psychiatry |
| Jahrgang/Volume einer Zeitschrift: | 13 |
| DOI: | 10.1038/s41398-023-02471-w |
| URL / URN: | https://www.nature.com/articles/s41398-023-02471-w |
| Kurzbeschreibung (Abstract): | Cognitive control deficits are a hallmark of attention deficit hyperactivity disorder (ADHD) in children. Theoretical models posit that cognitive control involves reactive and proactive control processes but their distinct roles and inter-relations in ADHD are not known, and the contributions of proactive control remain vastly understudied. Here, we investigate the dynamic dual cognitive control mechanisms associated with both proactive and reactive control in 50 children with ADHD (16F/34M) and 30 typically developing (TD) children (14F/16M) aged 9-12 years across two different cognitive controls tasks using a within-subject design. We found that while TD children were capable of proactively adapting their response strategies, children with ADHD demonstrated significant deficits in implementing proactive control strategies associated with error monitoring and trial history. Children with ADHD also showed weaker reactive control than TD children, and this finding was replicated across tasks. Furthermore, while proactive and reactive control functions were correlated in TD children, such coordination between the cognitive control mechanisms was not present in children with ADHD. Finally, both reactive and proactive control functions were associated with behavioral problems in ADHD, and multi-dimensional features derived from the dynamic dual cognitive control framework predicted inattention and hyperactivity/impulsivity clinical symptoms. Our findings demonstrate that ADHD in children is characterized by deficits in both proactive and reactive control, and suggest that multi-componential cognitive control measures can serve as robust predictors of clinical symptoms. |
| Zusätzliche Informationen: | 1 citations (Crossref) 2023-10-13; Article number: 179 |
| Fachbereich(e)/-gebiet(e): | 03 Fachbereich Humanwissenschaften 03 Fachbereich Humanwissenschaften > Institut für Psychologie |
| Hinterlegungsdatum: | 26 Okt 2023 12:59 |
| Letzte Änderung: | 27 Okt 2023 06:32 |
| PPN: | 512714665 |
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| Suche nach Titel in: | TUfind oder in Google |
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