Brust, M. ; Schäfer, C. ; Dörr, Roland ; Pan, L. ; Garcia, M. ; Arratia, P. E. ; Wagner, C. (2013)
Rheology of human blood plasma: Viscoelastic versus Newtonian behavior.
In: Physical Review Letters, 110
doi: 10.1103/PhysRevLett.110.078305
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in the pure extensional flow of a capillary break-up rheometer. The influence of the viscoelasticity of blood plasma on capillary blood flow is tested in a microfluidic device with a contraction-expansion geometry. Differential pressure measurements revealed that the plasma has a pronounced flow resistance compared to that of pure water. Supple- mentary measurements indicate that the viscoelasticity of the plasma might even lead to viscoelastic instabilities under certain conditions. Our findings show that the viscoelastic properties of plasma should not be ignored in future studies on blood flow.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2013 |
| Autor(en): | Brust, M. ; Schäfer, C. ; Dörr, Roland ; Pan, L. ; Garcia, M. ; Arratia, P. E. ; Wagner, C. |
| Art des Eintrags: | Bibliographie |
| Titel: | Rheology of human blood plasma: Viscoelastic versus Newtonian behavior |
| Sprache: | Englisch |
| Publikationsjahr: | 15 Februar 2013 |
| Verlag: | American Physical Society |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Physical Review Letters |
| Jahrgang/Volume einer Zeitschrift: | 110 |
| DOI: | 10.1103/PhysRevLett.110.078305 |
| URL / URN: | https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.11... |
| Kurzbeschreibung (Abstract): | We investigate the rheological characteristics of human blood plasma in shear and elongational flows. While we can confirm a Newtonian behavior in shear flow within experimental resolution, we find a viscoelastic behavior of blood plasma in the pure extensional flow of a capillary break-up rheometer. The influence of the viscoelasticity of blood plasma on capillary blood flow is tested in a microfluidic device with a contraction-expansion geometry. Differential pressure measurements revealed that the plasma has a pronounced flow resistance compared to that of pure water. Supple- mentary measurements indicate that the viscoelasticity of the plasma might even lead to viscoelastic instabilities under certain conditions. Our findings show that the viscoelastic properties of plasma should not be ignored in future studies on blood flow. |
| Freie Schlagworte: | Blood, Blood plasma, Viscoelastic behavior, Newtonian Behavior, Rheology |
| Fachbereich(e)/-gebiet(e): | 18 Fachbereich Elektrotechnik und Informationstechnik 18 Fachbereich Elektrotechnik und Informationstechnik > Institut für Elektromechanische Konstruktionen (aufgelöst 18.12.2018) 18 Fachbereich Elektrotechnik und Informationstechnik > Mikrotechnik und Elektromechanische Systeme |
| Hinterlegungsdatum: | 07 Nov 2017 08:42 |
| Letzte Änderung: | 09 Mär 2022 08:39 |
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