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Radioactive Beams in Particle Therapy: Past, Present, and Future

Durante, Marco ; Parodi, Katia (2024)
Radioactive Beams in Particle Therapy: Past, Present, and Future.
In: Frontiers in Physics, 2020, 8
doi: 10.26083/tuprints-00017019
Artikel, Zweitveröffentlichung, Verlagsversion

WarnungEs ist eine neuere Version dieses Eintrags verfügbar.

Kurzbeschreibung (Abstract)

Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize the beam. Positron-emitting ions that can be visualized with PET imaging were already studied for therapy application during the pilot therapy project at the Lawrence Berkeley Laboratory, and later within the EULIMA EU project, the GSI therapy trial in Germany, MEDICIS at CERN, and at HIMAC in Japan. The results show that radioactive ion beams provide a large improvement in image quality and signal-to-noise ratio compared to stable ions. The main hindrance toward a clinical use of radioactive ions is their challenging production and the low intensities of the beams. New research projects are ongoing in Europe and Japan to assess the advantages of radioactive ion beams for therapy, to develop new detectors, and to build sources of radioactive ions for medical synchrotrons.

Typ des Eintrags: Artikel
Erschienen: 2024
Autor(en): Durante, Marco ; Parodi, Katia
Art des Eintrags: Zweitveröffentlichung
Titel: Radioactive Beams in Particle Therapy: Past, Present, and Future
Sprache: Englisch
Publikationsjahr: 12 März 2024
Ort: Darmstadt
Publikationsdatum der Erstveröffentlichung: 28 August 2020
Ort der Erstveröffentlichung: Lausanne
Verlag: Frontiers Media S.A.
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Frontiers in Physics
Jahrgang/Volume einer Zeitschrift: 8
Kollation: 13 Seiten
DOI: 10.26083/tuprints-00017019
URL / URN: https://tuprints.ulb.tu-darmstadt.de/17019
Zugehörige Links:
Herkunft: Zweitveröffentlichung DeepGreen
Kurzbeschreibung (Abstract):

Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize the beam. Positron-emitting ions that can be visualized with PET imaging were already studied for therapy application during the pilot therapy project at the Lawrence Berkeley Laboratory, and later within the EULIMA EU project, the GSI therapy trial in Germany, MEDICIS at CERN, and at HIMAC in Japan. The results show that radioactive ion beams provide a large improvement in image quality and signal-to-noise ratio compared to stable ions. The main hindrance toward a clinical use of radioactive ions is their challenging production and the low intensities of the beams. New research projects are ongoing in Europe and Japan to assess the advantages of radioactive ion beams for therapy, to develop new detectors, and to build sources of radioactive ions for medical synchrotrons.

Freie Schlagworte: particle therapy, radioactive ion beams, carbon ions, oxygen ions, PET
ID-Nummer: Artikel-ID: 326
Status: Verlagsversion
URN: urn:nbn:de:tuda-tuprints-170194
Zusätzliche Informationen:

This article is part of the Research Topic: Applied Nuclear Physics at Accelerators

Specialty section: This article was submitted to Medical Physics and Imaging, a section of the journal Frontiers in Physics

Sachgruppe der Dewey Dezimalklassifikatin (DDC): 500 Naturwissenschaften und Mathematik > 530 Physik
Fachbereich(e)/-gebiet(e): 05 Fachbereich Physik
05 Fachbereich Physik > Institut für Physik Kondensierter Materie (IPKM)
Hinterlegungsdatum: 12 Mär 2024 13:03
Letzte Änderung: 19 Mär 2024 10:20
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