Durante, Marco ; Parodi, Katia (2020)
Radioactive Beams in Particle Therapy: Past, Present, and Future.
In: Frontiers in Physics, 8
doi: 10.3389/fphy.2020.00326
Artikel, Bibliographie
Dies ist die neueste Version dieses Eintrags.
Kurzbeschreibung (Abstract)
Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize the beam. Positron-emitting ions that can be visualized with PET imaging were already studied for therapy application during the pilot therapy project at the Lawrence Berkeley Laboratory, and later within the EULIMA EU project, the GSI therapy trial in Germany, MEDICIS at CERN, and at HIMAC in Japan. The results show that radioactive ion beams provide a large improvement in image quality and signal-to-noise ratio compared to stable ions. The main hindrance toward a clinical use of radioactive ions is their challenging production and the low intensities of the beams. New research projects are ongoing in Europe and Japan to assess the advantages of radioactive ion beams for therapy, to develop new detectors, and to build sources of radioactive ions for medical synchrotrons.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2020 |
| Autor(en): | Durante, Marco ; Parodi, Katia |
| Art des Eintrags: | Bibliographie |
| Titel: | Radioactive Beams in Particle Therapy: Past, Present, and Future |
| Sprache: | Englisch |
| Publikationsjahr: | 28 August 2020 |
| Ort: | Lausanne |
| Verlag: | Frontiers Media S.A. |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Frontiers in Physics |
| Jahrgang/Volume einer Zeitschrift: | 8 |
| Kollation: | 13 Seiten |
| DOI: | 10.3389/fphy.2020.00326 |
| Zugehörige Links: | |
| Kurzbeschreibung (Abstract): | Heavy ion therapy can deliver high doses with high precision. However, image guidance is needed to reduce range uncertainty. Radioactive ions are potentially ideal projectiles for radiotherapy because their decay can be used to visualize the beam. Positron-emitting ions that can be visualized with PET imaging were already studied for therapy application during the pilot therapy project at the Lawrence Berkeley Laboratory, and later within the EULIMA EU project, the GSI therapy trial in Germany, MEDICIS at CERN, and at HIMAC in Japan. The results show that radioactive ion beams provide a large improvement in image quality and signal-to-noise ratio compared to stable ions. The main hindrance toward a clinical use of radioactive ions is their challenging production and the low intensities of the beams. New research projects are ongoing in Europe and Japan to assess the advantages of radioactive ion beams for therapy, to develop new detectors, and to build sources of radioactive ions for medical synchrotrons. |
| Freie Schlagworte: | particle therapy, radioactive ion beams, carbon ions, oxygen ions, PET |
| ID-Nummer: | Artikel-ID: 326 |
| Zusätzliche Informationen: | This article is part of the Research Topic: Applied Nuclear Physics at Accelerators Specialty section: This article was submitted to Medical Physics and Imaging, a section of the journal Frontiers in Physics |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 530 Physik |
| Fachbereich(e)/-gebiet(e): | 05 Fachbereich Physik 05 Fachbereich Physik > Institut für Physik Kondensierter Materie (IPKM) |
| Hinterlegungsdatum: | 19 Mär 2024 10:20 |
| Letzte Änderung: | 19 Mär 2024 10:20 |
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| Suche nach Titel in: | TUfind oder in Google |
Verfügbare Versionen dieses Eintrags
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Radioactive Beams in Particle Therapy: Past, Present, and Future. (deposited 12 Mär 2024 13:03)
- Radioactive Beams in Particle Therapy: Past, Present, and Future. (deposited 19 Mär 2024 10:20) [Gegenwärtig angezeigt]
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