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Federated Stain Normalization for Computational Pathology

Wagner, Nicolas ; Fuchs, Moritz ; Tolkach, Yuri ; Mukhopadhyay, Anirban (2022)
Federated Stain Normalization for Computational Pathology.
25th International Conference on Medical Image Computing and Computer-Assisted Intervention. Singapore (18.-22.09.2022)
doi: 10.1007/978-3-031-16434-7_2
Konferenzveröffentlichung, Bibliographie

Kurzbeschreibung (Abstract)

Although deep federated learning has received much attentionin recent years, progress has been made mainly in the context ofnatural images and barely for computational pathology. However, deep federated learning is an opportunity to create datasets that reflect the data diversity of many laboratories. Further, the effort of dataset construction can be divided among many. Unfortunately, existing algorithms cannot be easily applied to computational pathology since previous work presupposes that data distributions of laboratories must be similar. Thisis an unlikely assumption, mainly since different laboratories have different staining styles. As a solution, we propose BottleGAN, a generative model that can computationally align the staining styles of many laboratories and can be trained in a privacy-preserving manner to foster federated learning in computational pathology. We construct a heterogenic multi-institutional dataset based on the PESO segmentation dataset and improve the IOU by 42% compared to existing federated learning algorithms. An implementation of BottleGAN is available thttps://github.com/MECLabTUDA/BottleGAN.

Typ des Eintrags: Konferenzveröffentlichung
Erschienen: 2022
Autor(en): Wagner, Nicolas ; Fuchs, Moritz ; Tolkach, Yuri ; Mukhopadhyay, Anirban
Art des Eintrags: Bibliographie
Titel: Federated Stain Normalization for Computational Pathology
Sprache: Englisch
Publikationsjahr: 16 September 2022
Verlag: Springer
Buchtitel: Medical Image Computing and Computer Assisted Intervention - MICCAI 2022
Reihe: Lecture Notes in Computer Science
Band einer Reihe: 13432
Veranstaltungstitel: 25th International Conference on Medical Image Computing and Computer-Assisted Intervention
Veranstaltungsort: Singapore
Veranstaltungsdatum: 18.-22.09.2022
DOI: 10.1007/978-3-031-16434-7_2
Kurzbeschreibung (Abstract):

Although deep federated learning has received much attentionin recent years, progress has been made mainly in the context ofnatural images and barely for computational pathology. However, deep federated learning is an opportunity to create datasets that reflect the data diversity of many laboratories. Further, the effort of dataset construction can be divided among many. Unfortunately, existing algorithms cannot be easily applied to computational pathology since previous work presupposes that data distributions of laboratories must be similar. Thisis an unlikely assumption, mainly since different laboratories have different staining styles. As a solution, we propose BottleGAN, a generative model that can computationally align the staining styles of many laboratories and can be trained in a privacy-preserving manner to foster federated learning in computational pathology. We construct a heterogenic multi-institutional dataset based on the PESO segmentation dataset and improve the IOU by 42% compared to existing federated learning algorithms. An implementation of BottleGAN is available thttps://github.com/MECLabTUDA/BottleGAN.

Freie Schlagworte: Federated learning, Computational pathology, Deep learning
Fachbereich(e)/-gebiet(e): 20 Fachbereich Informatik
20 Fachbereich Informatik > Graphisch-Interaktive Systeme
Hinterlegungsdatum: 15 Jun 2023 07:40
Letzte Änderung: 10 Aug 2023 15:00
PPN: 510504329
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