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A refined model of water and CO2 membrane diffusion: Effects and contribution of sterols and proteins.

Kai, Lei ; Kaldenhoff, Ralf (2014)
A refined model of water and CO2 membrane diffusion: Effects and contribution of sterols and proteins.
In: Scientific reports, 4
Artikel, Bibliographie

Kurzbeschreibung (Abstract)

Black lipid bilayers, a general model system for biomembranes were studied for diffusion rates of small molecules such as water or CO2 using advanced analysis techniques and cell free synthesized proteins. We provide evidence that by simple insertion of proteins or sterols the diffusion rates of water or those of CO2 decrease. Insertion of cell free synthesized water permeable aquaporins restored water diffusion rates as well as insertion of CO2-facilitating aquaporins the CO2 diffusion. Insertion of water or CO2 impermeable proteins decreased the respective diffusion rates. Therefore, for normal high cellular CO2 diffusion rates specific aquaporins are mandatory.

Typ des Eintrags: Artikel
Erschienen: 2014
Autor(en): Kai, Lei ; Kaldenhoff, Ralf
Art des Eintrags: Bibliographie
Titel: A refined model of water and CO2 membrane diffusion: Effects and contribution of sterols and proteins.
Sprache: Englisch
Publikationsjahr: 2014
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Scientific reports
Jahrgang/Volume einer Zeitschrift: 4
Kurzbeschreibung (Abstract):

Black lipid bilayers, a general model system for biomembranes were studied for diffusion rates of small molecules such as water or CO2 using advanced analysis techniques and cell free synthesized proteins. We provide evidence that by simple insertion of proteins or sterols the diffusion rates of water or those of CO2 decrease. Insertion of cell free synthesized water permeable aquaporins restored water diffusion rates as well as insertion of CO2-facilitating aquaporins the CO2 diffusion. Insertion of water or CO2 impermeable proteins decreased the respective diffusion rates. Therefore, for normal high cellular CO2 diffusion rates specific aquaporins are mandatory.

Fachbereich(e)/-gebiet(e): 10 Fachbereich Biologie
10 Fachbereich Biologie > Applied Plant Sciences
Hinterlegungsdatum: 30 Okt 2014 06:58
Letzte Änderung: 30 Okt 2014 06:58
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