Groher, Florian ; Suess, Beatrix (2014)
Synthetic riboswitches - A tool comes of age.
In: Biochimica et biophysica acta - Gene regulation mechanisms, 1839 (10)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Within the last decade, it has become obvious that RNA plays an important role in regulating gene expression. This has led to a plethora of approaches aiming at exploiting the outstanding chemical properties of RNA to develop artificial RNA regulators for conditional gene expression systems. Consequently, many different regulators have been developed to act on various stages of gene expression. They can be engineered to respond to almost any ligand of choice and are, therefore, of great interest for applications in synthetic biology. This review presents an overview of such engineered riboswitches, discusses their applicability and points out recent trends in their development. This article is part of a Special Issue entitled: Riboswitches.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2014 |
| Autor(en): | Groher, Florian ; Suess, Beatrix |
| Art des Eintrags: | Bibliographie |
| Titel: | Synthetic riboswitches - A tool comes of age. |
| Sprache: | Englisch |
| Publikationsjahr: | 2014 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Biochimica et biophysica acta - Gene regulation mechanisms |
| Jahrgang/Volume einer Zeitschrift: | 1839 |
| (Heft-)Nummer: | 10 |
| Kurzbeschreibung (Abstract): | Within the last decade, it has become obvious that RNA plays an important role in regulating gene expression. This has led to a plethora of approaches aiming at exploiting the outstanding chemical properties of RNA to develop artificial RNA regulators for conditional gene expression systems. Consequently, many different regulators have been developed to act on various stages of gene expression. They can be engineered to respond to almost any ligand of choice and are, therefore, of great interest for applications in synthetic biology. This review presents an overview of such engineered riboswitches, discusses their applicability and points out recent trends in their development. This article is part of a Special Issue entitled: Riboswitches. |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Synthetic Genetic Circuits (2020 umbenannt in "Synthetic RNA biology") |
| Hinterlegungsdatum: | 27 Mai 2014 11:14 |
| Letzte Änderung: | 20 Nov 2014 09:25 |
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