Detsch, Rainer ; Guillon, Olivier ; Wondraczek, Lothar ; Boccaccini, Aldo R. (2012)
Initial Attatchment of rMSC and MG-63 Cells on Patterned Bioglass® Substrates.
In: Advanced Engineering Materials, 14 (3)
doi: 10.1002/adem.201180068
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
A soft lithography technique was used to introduce surface patterns on the surface of sintered bioactive glass substrates. Osteoblast-like MG-63 cells and rat mesenchymal stem cells (rMSC) seeded on micropatterned bioactive glass surfaces showed different behavior with rMSC exhibiting a better initial attachment than MG-63 cells. Both cytoskeleton formation and cell spreading of rMSC were supported by the bioactive surfaces. In addition, the structured surfaces seemed to guide MG-63 cells to a larger extent than rMSC. The in vitro results are important considering the continuous development of bone tissue scaffolds based on silicate bioactive glasses.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2012 |
| Autor(en): | Detsch, Rainer ; Guillon, Olivier ; Wondraczek, Lothar ; Boccaccini, Aldo R. |
| Art des Eintrags: | Bibliographie |
| Titel: | Initial Attatchment of rMSC and MG-63 Cells on Patterned Bioglass® Substrates |
| Sprache: | Englisch |
| Publikationsjahr: | März 2012 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Advanced Engineering Materials |
| Jahrgang/Volume einer Zeitschrift: | 14 |
| (Heft-)Nummer: | 3 |
| DOI: | 10.1002/adem.201180068 |
| Kurzbeschreibung (Abstract): | A soft lithography technique was used to introduce surface patterns on the surface of sintered bioactive glass substrates. Osteoblast-like MG-63 cells and rat mesenchymal stem cells (rMSC) seeded on micropatterned bioactive glass surfaces showed different behavior with rMSC exhibiting a better initial attachment than MG-63 cells. Both cytoskeleton formation and cell spreading of rMSC were supported by the bioactive surfaces. In addition, the structured surfaces seemed to guide MG-63 cells to a larger extent than rMSC. The in vitro results are important considering the continuous development of bone tissue scaffolds based on silicate bioactive glasses. |
| Fachbereich(e)/-gebiet(e): | 11 Fachbereich Material- und Geowissenschaften > Materialwissenschaft > Fachgebiet Nichtmetallisch-Anorganische Werkstoffe 11 Fachbereich Material- und Geowissenschaften > Materialwissenschaft 11 Fachbereich Material- und Geowissenschaften |
| Hinterlegungsdatum: | 07 Jan 2013 13:06 |
| Letzte Änderung: | 05 Mär 2013 10:04 |
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