Bauer, Gesine ; Suess, Beatrix (2006)
Engineered riboswitches as novel tools in molecular biology.
In: Journal of biotechnology, 124 (1)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
During the last years the great importance of RNA for regulating gene expression in all organisms has become obvious. Consequently, several recent approaches aim to utilize the outstanding chemical properties of RNA to develop artificial RNA regulators for conditional gene expression systems. A combination of rational design, in vitro selection and in vivo screening systems has been used to create a versatile set of RNA based molecular switches. These tools rely on diverse mechanisms and exhibit activity in several organisms. In this review, we summarize recent developments in the application of engineered riboswitches for gene regulation in vivo.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2006 |
| Autor(en): | Bauer, Gesine ; Suess, Beatrix |
| Art des Eintrags: | Bibliographie |
| Titel: | Engineered riboswitches as novel tools in molecular biology. |
| Sprache: | Englisch |
| Publikationsjahr: | 2006 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Journal of biotechnology |
| Jahrgang/Volume einer Zeitschrift: | 124 |
| (Heft-)Nummer: | 1 |
| Kurzbeschreibung (Abstract): | During the last years the great importance of RNA for regulating gene expression in all organisms has become obvious. Consequently, several recent approaches aim to utilize the outstanding chemical properties of RNA to develop artificial RNA regulators for conditional gene expression systems. A combination of rational design, in vitro selection and in vivo screening systems has been used to create a versatile set of RNA based molecular switches. These tools rely on diverse mechanisms and exhibit activity in several organisms. In this review, we summarize recent developments in the application of engineered riboswitches for gene regulation in vivo. |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie > Synthetic Genetic Circuits (2020 umbenannt in "Synthetic RNA biology") 10 Fachbereich Biologie |
| Hinterlegungsdatum: | 22 Feb 2012 10:36 |
| Letzte Änderung: | 05 Mär 2013 09:59 |
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