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The role of neurotrophins in developmental cortical plasticity.

Galuske, Ralf A. W. and Kim, D. S. and Singer, W. (1999):
The role of neurotrophins in developmental cortical plasticity.
In: Restorative neurology and neuroscience, pp. 115-24, 15, (2-3), ISSN 0922-6028,
[Article]

Abstract

The present data support the concept of an involvement of neurotrophins in cortical plasticity. However, our observations suggest for both neurotrophins, NGF and BDNF, a more complex role in the developing neocortex than serving simply as the substrate of an activity dependent competition process within the visual cortex. Moreover, the outcome of our study indicaties strong differences between BDNF and NGF concerning their involvement and locus of action in developmental plasticity.

Item Type: Article
Erschienen: 1999
Creators: Galuske, Ralf A. W. and Kim, D. S. and Singer, W.
Title: The role of neurotrophins in developmental cortical plasticity.
Language: English
Abstract:

The present data support the concept of an involvement of neurotrophins in cortical plasticity. However, our observations suggest for both neurotrophins, NGF and BDNF, a more complex role in the developing neocortex than serving simply as the substrate of an activity dependent competition process within the visual cortex. Moreover, the outcome of our study indicaties strong differences between BDNF and NGF concerning their involvement and locus of action in developmental plasticity.

Journal or Publication Title: Restorative neurology and neuroscience
Volume: 15
Number: 2-3
Divisions: 10 Department of Biology > Systems Neurophysiology
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10 Department of Biology
Date Deposited: 21 Feb 2012 13:24
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