Thiel, Gerhard ; Baumeister, Dirk ; Schroeder, Indra ; Kast, Stefan M. ; Etten, James L. van ; Moroni, Anna (2011)
Minimal art: or why small viral K(+) channels are good tools for understanding basic structure and function relations.
In: Biochimica et biophysica acta, 1808 (2)
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Some algal viruses contain genes that encode proteins with the hallmarks of K(+) channels. One feature of these proteins is that they are less than 100 amino acids in size, which make them truly minimal for a K(+) channel protein. That is, they consist of only the pore module present in more complex K(+) channels. The combination of miniature size and the functional robustness of the viral K(+) channels make them ideal model systems for studying how K(+) channels work. Here we summarize recent structure/function correlates from these channels, which provide insight into functional properties such as gating, pharmacology and sorting in cells.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2011 |
| Autor(en): | Thiel, Gerhard ; Baumeister, Dirk ; Schroeder, Indra ; Kast, Stefan M. ; Etten, James L. van ; Moroni, Anna |
| Art des Eintrags: | Bibliographie |
| Titel: | Minimal art: or why small viral K(+) channels are good tools for understanding basic structure and function relations. |
| Sprache: | Englisch |
| Publikationsjahr: | 2011 |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Biochimica et biophysica acta |
| Jahrgang/Volume einer Zeitschrift: | 1808 |
| (Heft-)Nummer: | 2 |
| Kurzbeschreibung (Abstract): | Some algal viruses contain genes that encode proteins with the hallmarks of K(+) channels. One feature of these proteins is that they are less than 100 amino acids in size, which make them truly minimal for a K(+) channel protein. That is, they consist of only the pore module present in more complex K(+) channels. The combination of miniature size and the functional robustness of the viral K(+) channels make them ideal model systems for studying how K(+) channels work. Here we summarize recent structure/function correlates from these channels, which provide insight into functional properties such as gating, pharmacology and sorting in cells. |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie ?? fb10_botanik ?? 10 Fachbereich Biologie > Plant Membrane Biophyscis (am 20.12.23 umbenannt in Biologie der Algen und Protozoen) |
| Hinterlegungsdatum: | 21 Jun 2011 11:57 |
| Letzte Änderung: | 20 Aug 2021 09:43 |
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