Richter, Christian ; Hohmann, Katharina F. ; Toews, Sabrina ; Mathieu, Daniel ; Altincekic, Nadide ; Bains, Jasleen Kaur ; Binas, Oliver ; Ceylan, Betül ; Duchardt-Ferner, Elke ; Ferner, Jan ; Fürtig, Boris ; Grün, J. Tassilo ; Hengesbach, Martin ; Hymon, Daniel ; Jonker, Hendrik R. A. ; Knezic, Bozana ; Korn, Sophie M. ; Landgraf, Tom ; Löhr, Frank ; Peter, Stephen A. ; Pyper, Dennis J. ; Qureshi, Nusrat S. ; Schlundt, Andreas ; Schnieders, Robbin ; Stirnal, Elke ; Sudakov, Alexey ; Vögele, Jennifer ; Weigand, Julia E. ; Wirmer-Bartoschek, Julia ; Witt, Kerstin ; Wöhnert, Jens ; Schwalbe, Harald ; Wacker, Anna (2021)
¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2.
In: Biomolecular NMR Assignments, 15 (2)
doi: 10.1007/s12104-021-10047-2
Artikel, Bibliographie
Dies ist die neueste Version dieses Eintrags.
Kurzbeschreibung (Abstract)
The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the ¹H, ¹³C and ¹⁵N chemical shift assignment of the 29 nucleotides-RNA construct 5_SL1, which denotes the native 27mer SL1 stabilized by an additional terminal G-C base-pair.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2021 |
| Autor(en): | Richter, Christian ; Hohmann, Katharina F. ; Toews, Sabrina ; Mathieu, Daniel ; Altincekic, Nadide ; Bains, Jasleen Kaur ; Binas, Oliver ; Ceylan, Betül ; Duchardt-Ferner, Elke ; Ferner, Jan ; Fürtig, Boris ; Grün, J. Tassilo ; Hengesbach, Martin ; Hymon, Daniel ; Jonker, Hendrik R. A. ; Knezic, Bozana ; Korn, Sophie M. ; Landgraf, Tom ; Löhr, Frank ; Peter, Stephen A. ; Pyper, Dennis J. ; Qureshi, Nusrat S. ; Schlundt, Andreas ; Schnieders, Robbin ; Stirnal, Elke ; Sudakov, Alexey ; Vögele, Jennifer ; Weigand, Julia E. ; Wirmer-Bartoschek, Julia ; Witt, Kerstin ; Wöhnert, Jens ; Schwalbe, Harald ; Wacker, Anna |
| Art des Eintrags: | Bibliographie |
| Titel: | ¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2 |
| Sprache: | Englisch |
| Publikationsjahr: | 2021 |
| Ort: | Dordrecht |
| Verlag: | Springer Netherlands |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Biomolecular NMR Assignments |
| Jahrgang/Volume einer Zeitschrift: | 15 |
| (Heft-)Nummer: | 2 |
| DOI: | 10.1007/s12104-021-10047-2 |
| Zugehörige Links: | |
| Kurzbeschreibung (Abstract): | The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7–33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the ¹H, ¹³C and ¹⁵N chemical shift assignment of the 29 nucleotides-RNA construct 5_SL1, which denotes the native 27mer SL1 stabilized by an additional terminal G-C base-pair. |
| Freie Schlagworte: | SARS-CoV-2, 5'-UTR, SL1, Solution NMR spectroscopy, COVID19-NMR |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 540 Chemie 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > RNA Biochemie |
| Hinterlegungsdatum: | 04 Okt 2024 08:32 |
| Letzte Änderung: | 04 Okt 2024 08:32 |
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| Suche nach Titel in: | TUfind oder in Google |
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¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2. (deposited 30 Sep 2024 12:07)
- ¹H, ¹³C and ¹⁵N assignment of stem-loop SL1 from the 5'-UTR of SARS-CoV-2. (deposited 04 Okt 2024 08:32) [Gegenwärtig angezeigt]
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