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The Importance of Dean Flow in Microfluidic Nanoparticle Synthesis: A ZIF-8 Case Study

Yu, Xiangjiang ; Andreo, Jacopo ; Walden, Madeline ; del Campo, Javier F. ; Basabe-Desmonts, Lourdes ; Benito-Lopez, Fernando ; Burg, Thomas P. ; Wuttke, Stefan (2023)
The Importance of Dean Flow in Microfluidic Nanoparticle Synthesis: A ZIF-8 Case Study.
In: Small Methods, 8 (1)
doi: 10.1002/smtd.202300603
Artikel, Bibliographie

Kurzbeschreibung (Abstract)

The Dean Flow, a physics phenomenon that accounts for the impact of channel curvature on fluid dynamics, has great potential to be used in microfluidic synthesis of nanoparticles. This study explores the impact of the Dean Flow on the synthesis of ZIF-8 particles. Several variables that influence the Dean Equation (the mathematical expression of Dean Flow) are tested to validate the applicability of this expression in microfluidic synthesis, including the flow rate, radius of curvature, channel cross sectional area, and reagent concentration. It is demonstrated that the current standard of reporting, providing only the flow rate and crucially not the radius of curvature, is an incomplete description that will invariably lead to irreproducible syntheses across different laboratories. An alternative standard of reporting is presented and it is demonstrated how the sleek and simple math of the Dean Equation can be used to precisely tune the final dimensions of high quality, monodisperse ZIF-8 nanoparticles between 40 and 700 nm.

Typ des Eintrags: Artikel
Erschienen: 2023
Autor(en): Yu, Xiangjiang ; Andreo, Jacopo ; Walden, Madeline ; del Campo, Javier F. ; Basabe-Desmonts, Lourdes ; Benito-Lopez, Fernando ; Burg, Thomas P. ; Wuttke, Stefan
Art des Eintrags: Bibliographie
Titel: The Importance of Dean Flow in Microfluidic Nanoparticle Synthesis: A ZIF-8 Case Study
Sprache: Englisch
Publikationsjahr: 29 September 2023
Verlag: Wiley-VCH
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Small Methods
Jahrgang/Volume einer Zeitschrift: 8
(Heft-)Nummer: 1
DOI: 10.1002/smtd.202300603
URL / URN: https://onlinelibrary.wiley.com/doi/full/10.1002/smtd.202300...
Kurzbeschreibung (Abstract):

The Dean Flow, a physics phenomenon that accounts for the impact of channel curvature on fluid dynamics, has great potential to be used in microfluidic synthesis of nanoparticles. This study explores the impact of the Dean Flow on the synthesis of ZIF-8 particles. Several variables that influence the Dean Equation (the mathematical expression of Dean Flow) are tested to validate the applicability of this expression in microfluidic synthesis, including the flow rate, radius of curvature, channel cross sectional area, and reagent concentration. It is demonstrated that the current standard of reporting, providing only the flow rate and crucially not the radius of curvature, is an incomplete description that will invariably lead to irreproducible syntheses across different laboratories. An alternative standard of reporting is presented and it is demonstrated how the sleek and simple math of the Dean Equation can be used to precisely tune the final dimensions of high quality, monodisperse ZIF-8 nanoparticles between 40 and 700 nm.

Fachbereich(e)/-gebiet(e): 18 Fachbereich Elektrotechnik und Informationstechnik
18 Fachbereich Elektrotechnik und Informationstechnik > Integrierte Mikro-Nano-Systeme
Hinterlegungsdatum: 11 Sep 2024 08:24
Letzte Änderung: 24 Okt 2024 07:06
PPN: 522447260
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