Wesp, Svenja ; Wolf, Kai ; Immel, Stefan ; Reggelin, Michael (2022)
Poly(arylisocyanides) as Versatile, Enantiodiscriminating Alignment Media for Small Molecules.
In: ChemPlusChem, 87 (1)
doi: 10.1002/cplu.202100507
Artikel, Bibliographie
Dies ist die neueste Version dieses Eintrags.
Kurzbeschreibung (Abstract)
Lyotropic liquid crystalline (LLC) phases of amino acid derived polyarylisocyanides were employed as chiral alignment media for the measurement of residual dipolar couplings (RDCs) of small chiral organic molecules. Anisotropic samples in CDCl₃ displayed quadrupolar splittings of the deuterium signal in the range of several hundreds of Hertz. The LLC phases showed excellent orienting properties for a broad range of analytes bearing various functional groups. The precise extraction of RDCs in the range of up to ±40 Hertz from F2‐coupled HSQC spectra was possible. Additionally, the chiral environment offers the opportunity for diastereomorphous interactions with the enantiomers of chiral analytes leading to two different sets of RDCs. This differential order effect was particularly pronounced with ketones and alcohols.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2022 |
| Autor(en): | Wesp, Svenja ; Wolf, Kai ; Immel, Stefan ; Reggelin, Michael |
| Art des Eintrags: | Bibliographie |
| Titel: | Poly(arylisocyanides) as Versatile, Enantiodiscriminating Alignment Media for Small Molecules |
| Sprache: | Englisch |
| Publikationsjahr: | 2022 |
| Ort: | Darmstadt |
| Verlag: | Wiley-VCH |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | ChemPlusChem |
| Jahrgang/Volume einer Zeitschrift: | 87 |
| (Heft-)Nummer: | 1 |
| Kollation: | 8 Seiten |
| DOI: | 10.1002/cplu.202100507 |
| Zugehörige Links: | |
| Kurzbeschreibung (Abstract): | Lyotropic liquid crystalline (LLC) phases of amino acid derived polyarylisocyanides were employed as chiral alignment media for the measurement of residual dipolar couplings (RDCs) of small chiral organic molecules. Anisotropic samples in CDCl₃ displayed quadrupolar splittings of the deuterium signal in the range of several hundreds of Hertz. The LLC phases showed excellent orienting properties for a broad range of analytes bearing various functional groups. The precise extraction of RDCs in the range of up to ±40 Hertz from F2‐coupled HSQC spectra was possible. Additionally, the chiral environment offers the opportunity for diastereomorphous interactions with the enantiomers of chiral analytes leading to two different sets of RDCs. This differential order effect was particularly pronounced with ketones and alcohols. |
| Freie Schlagworte: | anisotropic phases, helical chirality, lyotropic liquid crystals, NMR, polymers |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 540 Chemie |
| Fachbereich(e)/-gebiet(e): | 07 Fachbereich Chemie 07 Fachbereich Chemie > Clemens-Schöpf-Institut 07 Fachbereich Chemie > Clemens-Schöpf-Institut > Fachgebiet Organische Chemie |
| Hinterlegungsdatum: | 02 Aug 2024 12:42 |
| Letzte Änderung: | 02 Aug 2024 12:42 |
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| Suche nach Titel in: | TUfind oder in Google |
Verfügbare Versionen dieses Eintrags
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Poly(arylisocyanides) as Versatile, Enantiodiscriminating Alignment Media for Small Molecules. (deposited 24 Jun 2022 12:45)
- Poly(arylisocyanides) as Versatile, Enantiodiscriminating Alignment Media for Small Molecules. (deposited 02 Aug 2024 12:42) [Gegenwärtig angezeigt]
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