Sethmann, Ingo ; Völkel, Sabrina ; Pfeifer, Felicitas ; Kleebe, Hans-Joachim (2018)
Development of Phosphatized Calcium Carbonate Biominerals as Bioactive Bone Graft Substitute Materials. Part II: Functionalization with Antibacterial Silver Ions.
In: Journal of Functional Biomaterials, 9 (4)
doi: 10.3390/jfb9040067
Artikel, Bibliographie
Dies ist die neueste Version dieses Eintrags.
Kurzbeschreibung (Abstract)
Porous calcium phosphate (CaP) materials as bone graft substitutes can be prepared from Ca carbonate biomineral structures by hydrothermal conversion into pseudomorphic CaP scaffolds. The present study aims at furnishing such phosphatized Ca carbonate biomineral (PCCB) materials with antibacterial Ag ions in order to avoid perisurgical wound infections. Prior to this study, PCCB materials with Mg and/or Sr ions incorporated for stimulating bone formation were prepared from coral skeletons and sea urchin spines as starting materials. The porous PCCB materials were treated with aqueous solutions of Ag nitrate with concentrations of 10 or 100 mmol/L, resulting in the formation of Ag phosphate nanoparticles on the sample surfaces through a replacement reaction. The materials were characterized using scanning electron microscopy (SEM) energy-dispersive X-ray spectroscopy (EDS) and X-ray diffractometry (XRD). In contact with Ringer‘s solution, the Ag phosphate nanoparticles dissolved and released Ag ions with concentrations up to 0.51 mg/L, as shown by atomic absorption spectroscopy (AAS) analyses. In tests against Pseudomonas aeruginosa and Staphylococcus aureus on agar plates, antibacterial properties were similar for both types of Ag-modified PCCB materials. Concerning the antibacterial performance, the treatment with AgNO3 solutions with 10 mmol/L was almost as effective as with 100 mmol/L.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2018 |
| Autor(en): | Sethmann, Ingo ; Völkel, Sabrina ; Pfeifer, Felicitas ; Kleebe, Hans-Joachim |
| Art des Eintrags: | Bibliographie |
| Titel: | Development of Phosphatized Calcium Carbonate Biominerals as Bioactive Bone Graft Substitute Materials. Part II: Functionalization with Antibacterial Silver Ions |
| Sprache: | Englisch |
| Publikationsjahr: | 2018 |
| Verlag: | MDPI |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Journal of Functional Biomaterials |
| Jahrgang/Volume einer Zeitschrift: | 9 |
| (Heft-)Nummer: | 4 |
| DOI: | 10.3390/jfb9040067 |
| URL / URN: | https://www.mdpi.com/2079-4983/9/4/67 |
| Zugehörige Links: | |
| Kurzbeschreibung (Abstract): | Porous calcium phosphate (CaP) materials as bone graft substitutes can be prepared from Ca carbonate biomineral structures by hydrothermal conversion into pseudomorphic CaP scaffolds. The present study aims at furnishing such phosphatized Ca carbonate biomineral (PCCB) materials with antibacterial Ag ions in order to avoid perisurgical wound infections. Prior to this study, PCCB materials with Mg and/or Sr ions incorporated for stimulating bone formation were prepared from coral skeletons and sea urchin spines as starting materials. The porous PCCB materials were treated with aqueous solutions of Ag nitrate with concentrations of 10 or 100 mmol/L, resulting in the formation of Ag phosphate nanoparticles on the sample surfaces through a replacement reaction. The materials were characterized using scanning electron microscopy (SEM) energy-dispersive X-ray spectroscopy (EDS) and X-ray diffractometry (XRD). In contact with Ringer‘s solution, the Ag phosphate nanoparticles dissolved and released Ag ions with concentrations up to 0.51 mg/L, as shown by atomic absorption spectroscopy (AAS) analyses. In tests against Pseudomonas aeruginosa and Staphylococcus aureus on agar plates, antibacterial properties were similar for both types of Ag-modified PCCB materials. Concerning the antibacterial performance, the treatment with AgNO3 solutions with 10 mmol/L was almost as effective as with 100 mmol/L. |
| ID-Nummer: | pmid:30477123 |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 550 Geowissenschaften |
| Fachbereich(e)/-gebiet(e): | 10 Fachbereich Biologie 10 Fachbereich Biologie > Microbiology and Archaea 11 Fachbereich Material- und Geowissenschaften 11 Fachbereich Material- und Geowissenschaften > Geowissenschaften 11 Fachbereich Material- und Geowissenschaften > Geowissenschaften > Fachgebiet Geomaterialwissenschaft |
| Hinterlegungsdatum: | 02 Jul 2024 23:05 |
| Letzte Änderung: | 02 Jul 2024 23:05 |
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Development of Phosphatized Calcium Carbonate Biominerals as Bioactive Bone Graft Substitute Materials. Part II: Functionalization with Antibacterial Silver Ions. (deposited 10 Feb 2019 20:55)
- Development of Phosphatized Calcium Carbonate Biominerals as Bioactive Bone Graft Substitute Materials. Part II: Functionalization with Antibacterial Silver Ions. (deposited 02 Jul 2024 23:05) [Gegenwärtig angezeigt]
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