Chandra, Siddharth ; Kassens-Noor, Eva (2014)
The evolution of pandemic influenza: evidence from India, 1918–19.
In: BMC infectious diseases, 14
doi: 10.1186/1471-2334-14-510
Artikel, Bibliographie
Kurzbeschreibung (Abstract)
Background The 1918–19 ‘Spanish’ Influenza was the most devastating pandemic in recent history, with estimates of global mortality ranging from 20 to 50 million. The focal point of the pandemic was India, with an estimated death toll of between 10 and 20 million. We will characterize the pattern of spread, mortality, and evolution of the 1918 influenza across India using spatial or temporal data.
Methods This study estimates weekly deaths in 213 districts from nine provinces in India. We compute statistical measures of the severity, speed, and duration of the virulent autumn wave of the disease as it evolved and diffused throughout India. These estimates create a clear picture of the spread of the pandemic across India.
Results Analysis of the timing and mortality patterns of the disease reveals a striking pattern of speed deceleration, reduction in peak-week mortality, a prolonging of the epidemic wave, and a decrease in overall virulence of the pandemic over time.
Conclusions The findings are consistent with a variety of possible causes, including the changing nature of the dominant viral strain and the timing and severity of the monsoon. The results significantly advance our knowledge of this devastating pandemic at its global focal point.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2014 |
| Autor(en): | Chandra, Siddharth ; Kassens-Noor, Eva |
| Art des Eintrags: | Bibliographie |
| Titel: | The evolution of pandemic influenza: evidence from India, 1918–19 |
| Sprache: | Englisch |
| Publikationsjahr: | Dezember 2014 |
| Verlag: | BioMed Central |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | BMC infectious diseases |
| Jahrgang/Volume einer Zeitschrift: | 14 |
| Kollation: | 10 Seiten |
| DOI: | 10.1186/1471-2334-14-510 |
| Kurzbeschreibung (Abstract): | Background The 1918–19 ‘Spanish’ Influenza was the most devastating pandemic in recent history, with estimates of global mortality ranging from 20 to 50 million. The focal point of the pandemic was India, with an estimated death toll of between 10 and 20 million. We will characterize the pattern of spread, mortality, and evolution of the 1918 influenza across India using spatial or temporal data. Methods This study estimates weekly deaths in 213 districts from nine provinces in India. We compute statistical measures of the severity, speed, and duration of the virulent autumn wave of the disease as it evolved and diffused throughout India. These estimates create a clear picture of the spread of the pandemic across India. Results Analysis of the timing and mortality patterns of the disease reveals a striking pattern of speed deceleration, reduction in peak-week mortality, a prolonging of the epidemic wave, and a decrease in overall virulence of the pandemic over time. Conclusions The findings are consistent with a variety of possible causes, including the changing nature of the dominant viral strain and the timing and severity of the monsoon. The results significantly advance our knowledge of this devastating pandemic at its global focal point. |
| Zusätzliche Informationen: | Artikel-ID: 510 |
| Fachbereich(e)/-gebiet(e): | 13 Fachbereich Bau- und Umweltingenieurwissenschaften 13 Fachbereich Bau- und Umweltingenieurwissenschaften > Verbund Institute für Verkehr 13 Fachbereich Bau- und Umweltingenieurwissenschaften > Verbund Institute für Verkehr > Institut für Verkehrsplanung und Verkehrstechnik |
| Hinterlegungsdatum: | 25 Mär 2024 09:14 |
| Letzte Änderung: | 25 Mär 2024 09:14 |
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