Boscolo, Daria ; Kostyleva, Daria ; Safari, Mohammad Javad ; Anagnostatou, Vasiliki ; Äystö, Juha ; Bagchi, Soumya ; Binder, Tim ; Dedes, Georgios ; Dendooven, Peter ; Dickel, Timo ; Drozd, Vasyl ; Franczack, Bernhard ; Geissel, Hans ; Gianoli, Chiara ; Graeff, Christian ; Grahn, Tuomas ; Greiner, Florian ; Haettner, Emma ; Haghani, Roghieh ; Harakeh, Muhsin N. ; Horst, Felix ; Hornung, Christine ; Hucka, Jan-Paul ; Kalantar-Nayestanaki, Nasser ; Kazantseva, Erika ; Kindler, Birgit ; Knöbel, Ronja ; Kuzminchuk-Feuerstein, Natalia ; Lommel, Bettina ; Mukha, Ivan ; Nociforo, Chiara ; Ishikawa, Shunki ; Lovatti, Giulio ; Nitta, Munetaka ; Ozoemelam, Ikechi ; Pietri, Stephane ; Plaß, Wolfgang R. ; Prochazka, Andrej ; Purushothaman, Sivaji ; Reidel, Claire-Anne ; Roesch, Heidi ; Schirru, Fabio ; Schuy, Christoph ; Sokol, Olga ; Steinsberger, Timo ; Tanaka, Yoshiki K. ; Tanihata, Isao ; Thirolf, Peter ; Tinganelli, Walter ; Voss, Bernd ; Weber, Uli ; Weick, Helmut ; Winfield, John S. ; Winkler, Martin ; Zhao, Jianwei ; Scheidenberger, Christoph ; Parodi, Katia ; Durante, Marco (2024)
Radioactive Beams for Image-Guided Particle Therapy: The BARB Experiment at GSI.
In: Frontiers in Oncology, 2021, 11
doi: 10.26083/tuprints-00019576
Artikel, Zweitveröffentlichung, Verlagsversion
 | Es ist eine neuere Version dieses Eintrags verfügbar. |
Kurzbeschreibung (Abstract)
Several techniques are under development for image-guidance in particle therapy. Positron (β⁺) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human body. In heavy ion therapy, a major part of the PET signals is produced by β⁺-emitters generated via projectile fragmentation. A much higher intensity for the PET signal can be obtained using β⁺-radioactive beams directly for treatment. This idea has always been hampered by the low intensity of the secondary beams, produced by fragmentation of the primary, stable beams. With the intensity upgrade of the SIS-18 synchrotron and the isotopic separation with the fragment separator FRS in the FAIR-phase-0 in Darmstadt, it is now possible to reach radioactive ion beams with sufficient intensity to treat a tumor in small animals. This was the motivation of the BARB (Biomedical Applications of Radioactive ion Beams) experiment that is ongoing at GSI in Darmstadt. This paper will present the plans and instruments developed by the BARB collaboration for testing the use of radioactive beams in cancer therapy.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2024 |
| Autor(en): | Boscolo, Daria ; Kostyleva, Daria ; Safari, Mohammad Javad ; Anagnostatou, Vasiliki ; Äystö, Juha ; Bagchi, Soumya ; Binder, Tim ; Dedes, Georgios ; Dendooven, Peter ; Dickel, Timo ; Drozd, Vasyl ; Franczack, Bernhard ; Geissel, Hans ; Gianoli, Chiara ; Graeff, Christian ; Grahn, Tuomas ; Greiner, Florian ; Haettner, Emma ; Haghani, Roghieh ; Harakeh, Muhsin N. ; Horst, Felix ; Hornung, Christine ; Hucka, Jan-Paul ; Kalantar-Nayestanaki, Nasser ; Kazantseva, Erika ; Kindler, Birgit ; Knöbel, Ronja ; Kuzminchuk-Feuerstein, Natalia ; Lommel, Bettina ; Mukha, Ivan ; Nociforo, Chiara ; Ishikawa, Shunki ; Lovatti, Giulio ; Nitta, Munetaka ; Ozoemelam, Ikechi ; Pietri, Stephane ; Plaß, Wolfgang R. ; Prochazka, Andrej ; Purushothaman, Sivaji ; Reidel, Claire-Anne ; Roesch, Heidi ; Schirru, Fabio ; Schuy, Christoph ; Sokol, Olga ; Steinsberger, Timo ; Tanaka, Yoshiki K. ; Tanihata, Isao ; Thirolf, Peter ; Tinganelli, Walter ; Voss, Bernd ; Weber, Uli ; Weick, Helmut ; Winfield, John S. ; Winkler, Martin ; Zhao, Jianwei ; Scheidenberger, Christoph ; Parodi, Katia ; Durante, Marco |
| Art des Eintrags: | Zweitveröffentlichung |
| Titel: | Radioactive Beams for Image-Guided Particle Therapy: The BARB Experiment at GSI |
| Sprache: | Englisch |
| Publikationsjahr: | 12 März 2024 |
| Ort: | Darmstadt |
| Publikationsdatum der Erstveröffentlichung: | 19 August 2021 |
| Ort der Erstveröffentlichung: | Lausanne |
| Verlag: | Frontiers Media S.A. |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Frontiers in Oncology |
| Jahrgang/Volume einer Zeitschrift: | 11 |
| Kollation: | 15 Seiten |
| DOI: | 10.26083/tuprints-00019576 |
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/19576 |
| Zugehörige Links: | |
| Herkunft: | Zweitveröffentlichung DeepGreen |
| Kurzbeschreibung (Abstract): | Several techniques are under development for image-guidance in particle therapy. Positron (β⁺) emission tomography (PET) is in use since many years, because accelerated ions generate positron-emitting isotopes by nuclear fragmentation in the human body. In heavy ion therapy, a major part of the PET signals is produced by β⁺-emitters generated via projectile fragmentation. A much higher intensity for the PET signal can be obtained using β⁺-radioactive beams directly for treatment. This idea has always been hampered by the low intensity of the secondary beams, produced by fragmentation of the primary, stable beams. With the intensity upgrade of the SIS-18 synchrotron and the isotopic separation with the fragment separator FRS in the FAIR-phase-0 in Darmstadt, it is now possible to reach radioactive ion beams with sufficient intensity to treat a tumor in small animals. This was the motivation of the BARB (Biomedical Applications of Radioactive ion Beams) experiment that is ongoing at GSI in Darmstadt. This paper will present the plans and instruments developed by the BARB collaboration for testing the use of radioactive beams in cancer therapy. |
| Freie Schlagworte: | particle therapy, radioactive ion beams, carbon ions, oxygen ions, PET |
| ID-Nummer: | Artikel-ID: 737050 |
| Status: | Verlagsversion |
| URN: | urn:nbn:de:tuda-tuprints-195769 |
| Zusätzliche Informationen: | This article is part of the Research Topic: Image-guided Particle Therapy Specialty section: This article was submitted to Cancer Imaging and Image-directed Interventions, a section of the journal Frontiers in Oncology |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 530 Physik 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin, Gesundheit |
| Fachbereich(e)/-gebiet(e): | 05 Fachbereich Physik 05 Fachbereich Physik > Institut für Physik Kondensierter Materie (IPKM) 05 Fachbereich Physik > Institut für Kernphysik 05 Fachbereich Physik > Institut für Kernphysik > Experimentelle Kernphysik |
| Hinterlegungsdatum: | 12 Mär 2024 13:19 |
| Letzte Änderung: | 19 Mär 2024 10:34 |
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| Suche nach Titel in: | TUfind oder in Google |
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- Radioactive Beams for Image-Guided Particle Therapy: The BARB Experiment at GSI. (deposited 12 Mär 2024 13:19) [Gegenwärtig angezeigt]
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