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Surface Properties of Aqueous Dispersions of Bovine Serum Albumin Fibrils

Akentiev, Alexander ; Lin, Shi-Yow ; Loglio, Giuseppe ; Miller, Reinhard ; Noskov, Boris (2023)
Surface Properties of Aqueous Dispersions of Bovine Serum Albumin Fibrils.
In: Colloids and Interfaces, 7 (3)
doi: 10.3390/colloids7030059
Artikel, Bibliographie

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Kurzbeschreibung (Abstract)

The surface properties of aqueous dispersions of worm-like fibril aggregates of bovine serum albumin (BSA) differ from those of the adsorption layers of the native protein. The dispersions of BSA fibrils are characterized by slower changes of the surface tension and dynamic surface elasticity and also have different steady-state values of the surface properties. The fourfold compression of the adsorption layer of BSA fibrils leads to noticeably higher surface pressures than those of a compressed layer of the native protein, indicating the formation of a more rigid layer structure in the former case. The spreading of BSA fibrils onto a liquid surface from a concentrated dispersion reduces the effect of surface-active admixtures on the layer properties. The dependencies of the dynamic surface elasticity on surface pressure almost coincide for the spread layers of fibrils and the native protein in the range of low surface pressures, but only the spreading of the native protein can lead to surface pressures higher than 4 mN/m. This distinction is presumably caused by the formation of stable clusters of BSA fibrils at the interface and their slow propagation along the liquid surface.

Typ des Eintrags: Artikel
Erschienen: 2023
Autor(en): Akentiev, Alexander ; Lin, Shi-Yow ; Loglio, Giuseppe ; Miller, Reinhard ; Noskov, Boris
Art des Eintrags: Bibliographie
Titel: Surface Properties of Aqueous Dispersions of Bovine Serum Albumin Fibrils
Sprache: Englisch
Publikationsjahr: 14 September 2023
Verlag: MDPI
Titel der Zeitschrift, Zeitung oder Schriftenreihe: Colloids and Interfaces
Jahrgang/Volume einer Zeitschrift: 7
(Heft-)Nummer: 3
Kollation: 12 Seiten
DOI: 10.3390/colloids7030059
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Kurzbeschreibung (Abstract):

The surface properties of aqueous dispersions of worm-like fibril aggregates of bovine serum albumin (BSA) differ from those of the adsorption layers of the native protein. The dispersions of BSA fibrils are characterized by slower changes of the surface tension and dynamic surface elasticity and also have different steady-state values of the surface properties. The fourfold compression of the adsorption layer of BSA fibrils leads to noticeably higher surface pressures than those of a compressed layer of the native protein, indicating the formation of a more rigid layer structure in the former case. The spreading of BSA fibrils onto a liquid surface from a concentrated dispersion reduces the effect of surface-active admixtures on the layer properties. The dependencies of the dynamic surface elasticity on surface pressure almost coincide for the spread layers of fibrils and the native protein in the range of low surface pressures, but only the spreading of the native protein can lead to surface pressures higher than 4 mN/m. This distinction is presumably caused by the formation of stable clusters of BSA fibrils at the interface and their slow propagation along the liquid surface.

Freie Schlagworte: bovine serum albumin fibrils, adsorbed layers, spread layers, surface dilational viscoelasticity, atomic force microscopy
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Erstveröffentlichung; Art.No.: 59

Sachgruppe der Dewey Dezimalklassifikatin (DDC): 500 Naturwissenschaften und Mathematik > 530 Physik
500 Naturwissenschaften und Mathematik > 540 Chemie
600 Technik, Medizin, angewandte Wissenschaften > 620 Ingenieurwissenschaften und Maschinenbau
Fachbereich(e)/-gebiet(e): 05 Fachbereich Physik
05 Fachbereich Physik > Institut für Physik Kondensierter Materie (IPKM)
Hinterlegungsdatum: 05 Mär 2024 11:36
Letzte Änderung: 05 Mär 2024 11:36
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