Velasquez, Sara T. R. ; Jang, Daseul ; Jenkins, Peter ; Liu, Peng ; Yang, Liu ; Korley, LaShanda T. J. ; Bruns, Nico (2024)
Peptide‐reinforced amphiphilic polymer conetworks.
In: Advanced Functional Materials, 2022, 32 (51)
doi: 10.26083/tuprints-00023688
Artikel, Zweitveröffentlichung, Verlagsversion
 | Es ist eine neuere Version dieses Eintrags verfügbar. |
Kurzbeschreibung (Abstract)
Amphiphilic polymer conetworks (APCNs) are polymer networks composed of hydrophilic and hydrophobic chain segments. Their applications range from soft contact lenses to membranes and biomaterials. APCNs based on polydimethylsiloxane (PDMS) and poly(2‐hydroxyethyl acrylate) are flexible and elastic in the dry and swollen state. However, they are not good at resisting deformation under load, i.e., their toughness is low. A bio‐inspired approach to reinforce APCNs is presented based on the incorporation of poly(β‐benzyl‐L‐aspartate) (PBLA) blocks between cross‐linking points and PDMS chain segments. The mechanical properties of the resulting peptide‐reinforced APCNs can be tailored by the secondary structure of the peptide chains (β‐sheets or a mixture of α‐helices and β‐sheets). Compared to non‐reinforced APCNs, the peptide‐reinforced networks have higher extensibility (53 vs. up to 341%), strength (0.71 ± 0.16 vs. 22.28 ± 2.81 MPa), and toughness (0.10 ± 0.04 vs. up to 4.85 ± 1.32 MJ m⁻³), as measured in their dry state. The PBLA peptides reversibly toughen and reinforce the APCNs, while other key material properties of APCNs are retained, such as optical transparency and swellability in water and organic solvents. This paves the way for applications of APCNs that benefit from significantly increased mechanical properties.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2024 |
| Autor(en): | Velasquez, Sara T. R. ; Jang, Daseul ; Jenkins, Peter ; Liu, Peng ; Yang, Liu ; Korley, LaShanda T. J. ; Bruns, Nico |
| Art des Eintrags: | Zweitveröffentlichung |
| Titel: | Peptide‐reinforced amphiphilic polymer conetworks |
| Sprache: | Englisch |
| Publikationsjahr: | 22 Januar 2024 |
| Ort: | Darmstadt |
| Publikationsdatum der Erstveröffentlichung: | 2022 |
| Ort der Erstveröffentlichung: | Weinheim |
| Verlag: | Wiley-VCH |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Advanced Functional Materials |
| Jahrgang/Volume einer Zeitschrift: | 32 |
| (Heft-)Nummer: | 51 |
| Kollation: | 15 Seiten |
| DOI: | 10.26083/tuprints-00023688 |
| URL / URN: | https://tuprints.ulb.tu-darmstadt.de/23688 |
| Zugehörige Links: | |
| Herkunft: | Zweitveröffentlichung DeepGreen |
| Kurzbeschreibung (Abstract): | Amphiphilic polymer conetworks (APCNs) are polymer networks composed of hydrophilic and hydrophobic chain segments. Their applications range from soft contact lenses to membranes and biomaterials. APCNs based on polydimethylsiloxane (PDMS) and poly(2‐hydroxyethyl acrylate) are flexible and elastic in the dry and swollen state. However, they are not good at resisting deformation under load, i.e., their toughness is low. A bio‐inspired approach to reinforce APCNs is presented based on the incorporation of poly(β‐benzyl‐L‐aspartate) (PBLA) blocks between cross‐linking points and PDMS chain segments. The mechanical properties of the resulting peptide‐reinforced APCNs can be tailored by the secondary structure of the peptide chains (β‐sheets or a mixture of α‐helices and β‐sheets). Compared to non‐reinforced APCNs, the peptide‐reinforced networks have higher extensibility (53 vs. up to 341%), strength (0.71 ± 0.16 vs. 22.28 ± 2.81 MPa), and toughness (0.10 ± 0.04 vs. up to 4.85 ± 1.32 MJ m⁻³), as measured in their dry state. The PBLA peptides reversibly toughen and reinforce the APCNs, while other key material properties of APCNs are retained, such as optical transparency and swellability in water and organic solvents. This paves the way for applications of APCNs that benefit from significantly increased mechanical properties. |
| Freie Schlagworte: | amphiphilic polymer networks, bio‐inspired polymeric materials, hydrogels, mechanical properties, peptide‐polymer hybrids, peptides, polymer reinforcements |
| ID-Nummer: | 2207317 |
| Status: | Verlagsversion |
| URN: | urn:nbn:de:tuda-tuprints-236881 |
| Sachgruppe der Dewey Dezimalklassifikatin (DDC): | 500 Naturwissenschaften und Mathematik > 540 Chemie 600 Technik, Medizin, angewandte Wissenschaften > 660 Technische Chemie |
| Fachbereich(e)/-gebiet(e): | Interdisziplinäre Forschungsprojekte Interdisziplinäre Forschungsprojekte > Centre for Synthetic Biology 07 Fachbereich Chemie 07 Fachbereich Chemie > Ernst-Berl-Institut > Fachgebiet Makromolekulare Chemie |
| Hinterlegungsdatum: | 22 Jan 2024 13:50 |
| Letzte Änderung: | 23 Jan 2024 09:09 |
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| Suche nach Titel in: | TUfind oder in Google |
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- Peptide‐reinforced amphiphilic polymer conetworks. (deposited 22 Jan 2024 13:50) [Gegenwärtig angezeigt]
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