Varol, H. Samet ; Förster, Claire ; Andrieu‐Brunsen, Annette (2023)
Ligand‐Binding Mediated Gradual Ionic Transport in Nanopores.
In: Advanced Materials Interfaces, 10 (8)
doi: 10.1002/admi.202201902
Artikel, Bibliographie
Dies ist die neueste Version dieses Eintrags.
Kurzbeschreibung (Abstract)
Selective binding of metal ions to their receptors at the cell membranes is essential for immune reactions, signaling, and opening/closing of the ion channels. Such ligand-binding-based pore activities inspire scientists to build metal-ion-responsive mesoporous films that can interact with metal ions to tune the ionic nanopore transport. However, to apply these mesoporous films in novel sensing and separation applications, their ligand-binding-triggered ionic pore transport needs to be understood fundamentally toward programming the transport of both anions and cations simultaneously and gradually. Herein, it is shown how Ca²⁺ ion concentration and attachment to the different chemistry silica nanopores tunes finely the nanopore transport of both anions and cations, especially for phosphate-containing polyelectrolyte (PMEP) functionalized mesopores. This biased ligand binding can gradually regulate the transport of anions and cations, whereas pores without polymers can gradually regulate only the anionic transport. Last, pore polymer functionality related to Ca²⁺ ion binding also diverts the pores’ adsorption/desorption (reversibility) response. Almost fully reversible Ca²⁺ binding is observed in non-functional pores and non-reversible C²⁺ binding at the PMEP-modified pores. It is also demonstrated that non/functional pores, even at sub-µm concentrations, bind only divalent Ca²⁺ ions, but they are not selective to trivalent Al³⁺ ions.
| Typ des Eintrags: | Artikel |
|---|---|
| Erschienen: | 2023 |
| Autor(en): | Varol, H. Samet ; Förster, Claire ; Andrieu‐Brunsen, Annette |
| Art des Eintrags: | Bibliographie |
| Titel: | Ligand‐Binding Mediated Gradual Ionic Transport in Nanopores |
| Sprache: | Englisch |
| Publikationsjahr: | 2023 |
| Ort: | Weinheim |
| Verlag: | Wiley |
| Titel der Zeitschrift, Zeitung oder Schriftenreihe: | Advanced Materials Interfaces |
| Jahrgang/Volume einer Zeitschrift: | 10 |
| (Heft-)Nummer: | 8 |
| Kollation: | 11 Seiten |
| DOI: | 10.1002/admi.202201902 |
| Zugehörige Links: | |
| Kurzbeschreibung (Abstract): | Selective binding of metal ions to their receptors at the cell membranes is essential for immune reactions, signaling, and opening/closing of the ion channels. Such ligand-binding-based pore activities inspire scientists to build metal-ion-responsive mesoporous films that can interact with metal ions to tune the ionic nanopore transport. However, to apply these mesoporous films in novel sensing and separation applications, their ligand-binding-triggered ionic pore transport needs to be understood fundamentally toward programming the transport of both anions and cations simultaneously and gradually. Herein, it is shown how Ca²⁺ ion concentration and attachment to the different chemistry silica nanopores tunes finely the nanopore transport of both anions and cations, especially for phosphate-containing polyelectrolyte (PMEP) functionalized mesopores. This biased ligand binding can gradually regulate the transport of anions and cations, whereas pores without polymers can gradually regulate only the anionic transport. Last, pore polymer functionality related to Ca²⁺ ion binding also diverts the pores’ adsorption/desorption (reversibility) response. Almost fully reversible Ca²⁺ binding is observed in non-functional pores and non-reversible C²⁺ binding at the PMEP-modified pores. It is also demonstrated that non/functional pores, even at sub-µm concentrations, bind only divalent Ca²⁺ ions, but they are not selective to trivalent Al³⁺ ions. |
| Fachbereich(e)/-gebiet(e): | DFG-Sonderforschungsbereiche (inkl. Transregio) DFG-Sonderforschungsbereiche (inkl. Transregio) > Sonderforschungsbereiche DFG-Sonderforschungsbereiche (inkl. Transregio) > Sonderforschungsbereiche > SFB 1194: Wechselseitige Beeinflussung von Transport- und Benetzungsvorgängen DFG-Sonderforschungsbereiche (inkl. Transregio) > Sonderforschungsbereiche > SFB 1194: Wechselseitige Beeinflussung von Transport- und Benetzungsvorgängen > Projektbereich C: Neue und verbesserte Anwendungen DFG-Sonderforschungsbereiche (inkl. Transregio) > Sonderforschungsbereiche > SFB 1194: Wechselseitige Beeinflussung von Transport- und Benetzungsvorgängen > Projektbereich C: Neue und verbesserte Anwendungen > C04: Dynamische Benetzungssteuerung und der Einfluss auf ionischen Stofftransport in mesoporöse Filme 07 Fachbereich Chemie 07 Fachbereich Chemie > Ernst-Berl-Institut > Fachgebiet Makromolekulare Chemie |
| Hinterlegungsdatum: | 07 Dez 2023 11:39 |
| Letzte Änderung: | 07 Dez 2023 11:41 |
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| Suche nach Titel in: | TUfind oder in Google |
Verfügbare Versionen dieses Eintrags
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Ligand‐Binding Mediated Gradual Ionic Transport in Nanopores. (deposited 12 Mai 2023 08:39)
- Ligand‐Binding Mediated Gradual Ionic Transport in Nanopores. (deposited 07 Dez 2023 11:39) [Gegenwärtig angezeigt]
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